Rattus norvegicus

76 known processes

Syne1

spectrin repeat containing, nuclear envelope 1

(Aliases: CPG2,Myne-1)

Syne1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.166
neuron projection morphogenesis GO:0048812 122 0.150
regulation of nervous system development GO:0051960 264 0.131
homeostatic process GO:0042592 331 0.114
cellular component assembly GO:0022607 360 0.109
neuron differentiation GO:0030182 368 0.090
cellular component biogenesis GO:0044085 368 0.090
cellular cation homeostasis GO:0030003 180 0.087
neurological system process GO:0050877 219 0.086
regulation of programmed cell death GO:0043067 341 0.085
reproductive process GO:0022414 372 0.083
cell projection organization GO:0030030 302 0.082
protein complex assembly GO:0006461 263 0.080
response to inorganic substance GO:0010035 377 0.078
intracellular signal transduction GO:0035556 314 0.076
single organism reproductive process GO:0044702 297 0.075
chemical homeostasis GO:0048878 292 0.072
central nervous system development GO:0007417 311 0.071
catabolic process GO:0009056 351 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.067
synaptic transmission GO:0007268 235 0.067
regulation of neuron projection development GO:0010975 161 0.066
nucleobase containing small molecule metabolic process GO:0055086 316 0.066
programmed cell death GO:0012501 392 0.066
apoptotic process GO:0006915 381 0.065
neuron projection development GO:0031175 273 0.065
cellular chemical homeostasis GO:0055082 247 0.064
regulation of signal transduction GO:0009966 318 0.061
macromolecular complex assembly GO:0065003 273 0.060
regulation of multicellular organismal development GO:2000026 376 0.060
cation transport GO:0006812 382 0.060
positive regulation of neurogenesis GO:0050769 165 0.056
positive regulation of neuron projection development GO:0010976 99 0.055
cellular ion homeostasis GO:0006873 184 0.053
organic substance catabolic process GO:1901575 316 0.053
organophosphate catabolic process GO:0046434 148 0.053
organic acid metabolic process GO:0006082 292 0.050
neuron development GO:0048666 286 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
glycosyl compound metabolic process GO:1901657 182 0.049
protein heterooligomerization GO:0051291 89 0.048
regulation of cell development GO:0060284 263 0.046
positive regulation of developmental process GO:0051094 283 0.045
regulation of membrane potential GO:0042391 110 0.045
brain development GO:0007420 247 0.045
divalent metal ion transport GO:0070838 132 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.045
cellular response to oxygen containing compound GO:1901701 386 0.045
single organism intracellular transport GO:1902582 166 0.044
positive regulation of nervous system development GO:0051962 178 0.044
negative regulation of signaling GO:0023057 157 0.043
cellular homeostasis GO:0019725 252 0.043
positive regulation of cellular component organization GO:0051130 200 0.042
regulation of neuron differentiation GO:0045664 208 0.042
organonitrogen compound catabolic process GO:1901565 179 0.042
regulation of ion transport GO:0043269 245 0.042
regulation of molecular function GO:0065009 398 0.042
purine nucleoside triphosphate metabolic process GO:0009144 141 0.042
cellular catabolic process GO:0044248 295 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
head development GO:0060322 247 0.040
ras protein signal transduction GO:0007265 29 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
developmental process involved in reproduction GO:0003006 159 0.039
response to extracellular stimulus GO:0009991 380 0.039
carboxylic acid metabolic process GO:0019752 289 0.039
response to purine containing compound GO:0014074 126 0.039
guanosine containing compound metabolic process GO:1901068 74 0.039
nucleoside phosphate metabolic process GO:0006753 283 0.038
cell projection morphogenesis GO:0048858 123 0.038
response to metal ion GO:0010038 253 0.038
anatomical structure morphogenesis GO:0009653 298 0.037
oxoacid metabolic process GO:0043436 290 0.037
response to camp GO:0051591 91 0.036
rna metabolic process GO:0016070 406 0.036
cellular divalent inorganic cation homeostasis GO:0072503 162 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.036
multi multicellular organism process GO:0044706 138 0.036
ribonucleotide metabolic process GO:0009259 231 0.036
regulation of phosphorylation GO:0042325 248 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
purine nucleoside metabolic process GO:0042278 169 0.035
nucleoside metabolic process GO:0009116 179 0.034
cation homeostasis GO:0055080 195 0.034
negative regulation of response to stimulus GO:0048585 155 0.033
cellular response to stress GO:0033554 269 0.033
regulation of neurogenesis GO:0050767 247 0.033
protein oligomerization GO:0051259 191 0.033
nucleic acid templated transcription GO:0097659 379 0.033
regulation of catabolic process GO:0009894 113 0.032
multicellular organism reproduction GO:0032504 233 0.032
ribonucleoside triphosphate catabolic process GO:0009203 122 0.032
regulation of hydrolase activity GO:0051336 143 0.032
transcription dna templated GO:0006351 377 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
regulation of catalytic activity GO:0050790 304 0.032
protein complex biogenesis GO:0070271 263 0.032
regulation of cell projection organization GO:0031344 175 0.031
ribonucleoside metabolic process GO:0009119 174 0.031
response to nutrient levels GO:0031667 370 0.031
inorganic cation transmembrane transport GO:0098662 202 0.031
monovalent inorganic cation transport GO:0015672 172 0.031
transmission of nerve impulse GO:0019226 42 0.031
response to organophosphorus GO:0046683 102 0.031
glycosyl compound catabolic process GO:1901658 126 0.031
metal ion transport GO:0030001 289 0.031
cell type specific apoptotic process GO:0097285 134 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
oxidation reduction process GO:0055114 304 0.030
negative regulation of cell communication GO:0010648 158 0.030
reproduction GO:0000003 245 0.030
multi organism reproductive process GO:0044703 262 0.030
ribonucleotide catabolic process GO:0009261 136 0.030
aromatic compound catabolic process GO:0019439 168 0.030
positive regulation of neuron differentiation GO:0045666 126 0.030
second messenger mediated signaling GO:0019932 51 0.030
regulation of rna metabolic process GO:0051252 391 0.029
carbohydrate derivative catabolic process GO:1901136 147 0.029
purine containing compound metabolic process GO:0072521 253 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
nucleoside triphosphate metabolic process GO:0009141 144 0.029
gamete generation GO:0007276 124 0.029
organic cyclic compound catabolic process GO:1901361 175 0.029
positive regulation of cell death GO:0010942 184 0.029
negative regulation of cellular biosynthetic process GO:0031327 161 0.029
sexual reproduction GO:0019953 148 0.028
organic hydroxy compound metabolic process GO:1901615 115 0.028
negative regulation of cell death GO:0060548 229 0.028
cellular calcium ion homeostasis GO:0006874 160 0.028
ribonucleoside triphosphate metabolic process GO:0009199 141 0.028
regulation of apoptotic process GO:0042981 335 0.028
single organism catabolic process GO:0044712 283 0.028
regulation of dendrite development GO:0050773 59 0.028
reproductive system development GO:0061458 128 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
protein complex subunit organization GO:0071822 302 0.027
cell morphogenesis GO:0000902 142 0.027
organophosphate metabolic process GO:0019637 370 0.027
metal ion homeostasis GO:0055065 186 0.027
axon ensheathment GO:0008366 40 0.027
monocarboxylic acid metabolic process GO:0032787 152 0.027
regulation of cellular component organization GO:0051128 368 0.027
ensheathment of neurons GO:0007272 40 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.026
response to estrogen GO:0043627 232 0.026
secretion GO:0046903 307 0.026
protein phosphorylation GO:0006468 345 0.026
gliogenesis GO:0042063 93 0.026
nucleotide metabolic process GO:0009117 279 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
purine nucleoside catabolic process GO:0006152 124 0.026
response to nutrient GO:0007584 248 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
positive regulation of cell development GO:0010720 176 0.025
ion transmembrane transport GO:0034220 365 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
regulation of homeostatic process GO:0032844 101 0.025
purine containing compound catabolic process GO:0072523 138 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
locomotion GO:0040011 237 0.024
mitotic spindle organization GO:0007052 2 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
positive regulation of transport GO:0051050 245 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
nucleotide catabolic process GO:0009166 139 0.024
learning or memory GO:0007611 90 0.024
guanosine containing compound catabolic process GO:1901069 71 0.024
cellular protein localization GO:0034613 122 0.024
nucleobase containing compound catabolic process GO:0034655 152 0.024
secretion by cell GO:0032940 248 0.024
divalent inorganic cation homeostasis GO:0072507 165 0.024
nitrogen compound transport GO:0071705 229 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
cellular amine metabolic process GO:0044106 38 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
regulation of proteasomal protein catabolic process GO:0061136 4 0.023
cellular component movement GO:0006928 248 0.023
protein localization GO:0008104 191 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
neuron death GO:0070997 127 0.023
single organism behavior GO:0044708 130 0.023
behavior GO:0007610 205 0.022
glutamate receptor signaling pathway GO:0007215 43 0.022
regulation of nucleoside metabolic process GO:0009118 66 0.022
adult locomotory behavior GO:0008344 4 0.022
regulation of secretion by cell GO:1903530 208 0.022
heterocycle catabolic process GO:0046700 167 0.022
regulation of nucleotide metabolic process GO:0006140 117 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
rna biosynthetic process GO:0032774 380 0.021
response to decreased oxygen levels GO:0036293 237 0.021
reproductive structure development GO:0048608 128 0.021
response to oxygen levels GO:0070482 265 0.021
insulin secretion GO:0030073 69 0.021
proteolysis GO:0006508 175 0.021
regulation of transcription dna templated GO:0006355 374 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
response to oxidative stress GO:0006979 186 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
response to mechanical stimulus GO:0009612 134 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
response to toxic substance GO:0009636 133 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
intracellular transport GO:0046907 185 0.020
calcium ion transport GO:0006816 131 0.020
organelle organization GO:0006996 266 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
motor neuron axon guidance GO:0008045 1 0.020
cell part morphogenesis GO:0032990 123 0.019
sensory perception GO:0007600 101 0.019
maintenance of location GO:0051235 17 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
regulation of metal ion transport GO:0010959 118 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
negative regulation of metabolic process GO:0009892 331 0.019
response to ketone GO:1901654 182 0.019
dendrite development GO:0016358 72 0.019
calcium mediated signaling GO:0019722 23 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
gtp catabolic process GO:0006184 71 0.019
spindle organization GO:0007051 2 0.019
divalent inorganic cation transport GO:0072511 134 0.019
purine ribonucleoside catabolic process GO:0046130 124 0.018
nuclear transport GO:0051169 49 0.018
development of primary sexual characteristics GO:0045137 107 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
negative regulation of developmental process GO:0051093 125 0.018
synaptic vesicle priming GO:0016082 4 0.018
mapk cascade GO:0000165 140 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
regulation of vesicle mediated transport GO:0060627 81 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
nucleoside catabolic process GO:0009164 126 0.018
protein transport GO:0015031 132 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
response to hypoxia GO:0001666 231 0.018
positive regulation of catabolic process GO:0009896 78 0.018
localization of cell GO:0051674 202 0.018
multicellular organismal signaling GO:0035637 44 0.017
cellular ketone metabolic process GO:0042180 51 0.017
axonogenesis GO:0007409 71 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
response to corticosteroid GO:0031960 235 0.017
axon development GO:0061564 96 0.017
potassium ion transport GO:0006813 97 0.017
neuronal action potential GO:0019228 35 0.017
cellular response to camp GO:0071320 26 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
regulation of cell differentiation GO:0045595 320 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
response to reactive oxygen species GO:0000302 120 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
response to acid chemical GO:0001101 222 0.017
regulation of cellular localization GO:0060341 263 0.016
regulation of locomotion GO:0040012 148 0.016
cytoplasmic transport GO:0016482 115 0.016
response to hydrogen peroxide GO:0042542 89 0.016
positive regulation of signaling GO:0023056 270 0.016
regulation of protein metabolic process GO:0051246 289 0.016
anion transport GO:0006820 178 0.016
positive regulation of nucleoside metabolic process GO:0045979 55 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
response to estradiol GO:0032355 164 0.016
regulation of neuron death GO:1901214 115 0.016
regulation of cell cycle GO:0051726 73 0.016
positive regulation of gene expression GO:0010628 244 0.016
ion homeostasis GO:0050801 212 0.016
positive regulation of signal transduction GO:0009967 175 0.016
cellular response to organonitrogen compound GO:0071417 197 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
peptide secretion GO:0002790 86 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
response to radiation GO:0009314 137 0.015
response to cytokine GO:0034097 215 0.015
myelination GO:0042552 39 0.015
neuron apoptotic process GO:0051402 88 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
multicellular organism growth GO:0035264 1 0.015
defense response GO:0006952 194 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
aging GO:0007568 241 0.015
cell cell signaling GO:0007267 335 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
positive regulation of transcription factor import into nucleus GO:0042993 4 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
response to carbohydrate GO:0009743 183 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
anion transmembrane transport GO:0098656 77 0.014
regulation of synaptic transmission GO:0050804 141 0.014
response to growth factor GO:0070848 189 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
protein import GO:0017038 37 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
regulation of anatomical structure size GO:0090066 135 0.014
protein import into nucleus GO:0006606 35 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
amine metabolic process GO:0009308 38 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of locomotion GO:0040017 102 0.014
cell cycle checkpoint GO:0000075 2 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
membrane repolarization GO:0086009 1 0.013
regulation of ras gtpase activity GO:0032318 32 0.013
regulation of cell proliferation GO:0042127 359 0.013
neuromuscular process GO:0050905 2 0.013
protein homooligomerization GO:0051260 91 0.013
cell cycle GO:0007049 101 0.013
negative regulation of ion transport GO:0043271 51 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
gonad development GO:0008406 104 0.013
blood circulation GO:0008015 183 0.013
response to vitamin GO:0033273 131 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
gtp metabolic process GO:0046039 72 0.013
chemosensory behavior GO:0007635 2 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
signal release GO:0023061 145 0.012
telencephalon development GO:0021537 62 0.012
inflammatory response GO:0006954 150 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
cellular macromolecule localization GO:0070727 122 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cell motility GO:0048870 202 0.012
synaptic transmission glutamatergic GO:0035249 33 0.012
male gamete generation GO:0048232 99 0.012
rhythmic process GO:0048511 156 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
macromolecule catabolic process GO:0009057 58 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
positive regulation of neuron apoptotic process GO:0043525 33 0.012
erythrocyte differentiation GO:0030218 1 0.012
negative regulation of cell development GO:0010721 82 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
regulation of dendrite morphogenesis GO:0048814 33 0.012
spermatogenesis GO:0007283 99 0.012
positive regulation of ion transport GO:0043270 94 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
axis specification GO:0009798 4 0.012
protein targeting GO:0006605 61 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
negative regulation of neuron death GO:1901215 69 0.012
negative regulation of molecular function GO:0044092 133 0.012
sensory organ development GO:0007423 74 0.012
regulation of cell migration GO:0030334 128 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
cellular response to oxygen levels GO:0071453 60 0.011
tissue development GO:0009888 252 0.011
lipid storage GO:0019915 1 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
response to peptide hormone GO:0043434 278 0.011
positive regulation of synapse maturation GO:0090129 2 0.011
regulation of ras protein signal transduction GO:0046578 45 0.011
regulation of defense response GO:0031347 68 0.011
dna integrity checkpoint GO:0031570 2 0.011
rho protein signal transduction GO:0007266 11 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
negative regulation of secretion GO:0051048 82 0.011
olfactory behavior GO:0042048 2 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
growth GO:0040007 165 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
regulation of calcium ion transport GO:0051924 77 0.011
regulation of secretion GO:0051046 224 0.011
positive regulation of dendritic spine development GO:0060999 9 0.011
negative regulation of gene expression GO:0010629 199 0.011
response to biotic stimulus GO:0009607 226 0.011
dicarboxylic acid metabolic process GO:0043648 42 0.011
dendrite morphogenesis GO:0048813 43 0.011
response to wounding GO:0009611 254 0.011
regulation of protein modification process GO:0031399 194 0.011
response to glucose GO:0009749 136 0.011
mitotic cell cycle GO:0000278 49 0.011
sequestering of calcium ion GO:0051208 8 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
vesicle mediated transport GO:0016192 181 0.011
calcium ion homeostasis GO:0055074 162 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
n methyl d aspartate receptor clustering GO:0097114 2 0.011
female pregnancy GO:0007565 122 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.010
response to increased oxygen levels GO:0036296 45 0.010
cytoskeleton organization GO:0007010 111 0.010
action potential GO:0001508 54 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
amide transport GO:0042886 105 0.010
detection of visible light GO:0009584 3 0.010
positive regulation of tor signaling GO:0032008 2 0.010
response to tumor necrosis factor GO:0034612 56 0.010
circulatory system development GO:0072359 134 0.010
muscle system process GO:0003012 115 0.010
single organism organelle organization GO:1902589 180 0.010
establishment of protein localization GO:0045184 141 0.010
response to fungicide GO:0060992 20 0.010
heart morphogenesis GO:0003007 3 0.010
cell migration GO:0016477 197 0.010

Syne1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
nervous system disease DOID:863 0 0.063
central nervous system disease DOID:331 0 0.046
epilepsy syndrome DOID:1826 0 0.016
brain disease DOID:936 0 0.016
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.011