Rattus norvegicus

0 known processes

Il21r

interleukin 21 receptor

(Aliases: MGC108921)

Il21r biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 107 0.038
organic acid metabolic process GO:0006082 292 0.037
oxoacid metabolic process GO:0043436 290 0.036
programmed cell death GO:0012501 392 0.034
negative regulation of metabolic process GO:0009892 331 0.033
regulation of multicellular organismal development GO:2000026 376 0.032
cellular amine metabolic process GO:0044106 38 0.032
intracellular signal transduction GO:0035556 314 0.032
neuron differentiation GO:0030182 368 0.032
amine metabolic process GO:0009308 38 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
regulation of rna metabolic process GO:0051252 391 0.030
reproductive process GO:0022414 372 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
regulation of cell differentiation GO:0045595 320 0.030
response to inorganic substance GO:0010035 377 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
catabolic process GO:0009056 351 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
response to nutrient levels GO:0031667 370 0.029
transmembrane transport GO:0055085 412 0.029
response to extracellular stimulus GO:0009991 380 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.028
ion transmembrane transport GO:0034220 365 0.028
central nervous system development GO:0007417 311 0.028
cell projection organization GO:0030030 302 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
cation transport GO:0006812 382 0.028
g protein coupled receptor signaling pathway GO:0007186 242 0.028
regulation of cellular component organization GO:0051128 368 0.027
regulation of signal transduction GO:0009966 318 0.027
cellular component assembly GO:0022607 360 0.027
protein phosphorylation GO:0006468 345 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
cellular ketone metabolic process GO:0042180 51 0.026
macromolecular complex assembly GO:0065003 273 0.026
chemical homeostasis GO:0048878 292 0.026
cellular component biogenesis GO:0044085 368 0.026
neuron projection development GO:0031175 273 0.026
cation transmembrane transport GO:0098655 263 0.026
regulation of cell development GO:0060284 263 0.025
positive regulation of developmental process GO:0051094 283 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
protein complex assembly GO:0006461 263 0.025
rna metabolic process GO:0016070 406 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
organophosphate metabolic process GO:0019637 370 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
apoptotic process GO:0006915 381 0.024
regulation of apoptotic process GO:0042981 335 0.024
regulation of nervous system development GO:0051960 264 0.024
cellular component movement GO:0006928 248 0.024
protein complex subunit organization GO:0071822 302 0.024
homeostatic process GO:0042592 331 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
regulation of protein metabolic process GO:0051246 289 0.024
regulation of molecular function GO:0065009 398 0.024
transcription dna templated GO:0006351 377 0.024
rna biosynthetic process GO:0032774 380 0.023
regulation of transcription dna templated GO:0006355 374 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of programmed cell death GO:0043067 341 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
nucleic acid templated transcription GO:0097659 379 0.023
regulation of catalytic activity GO:0050790 304 0.023
multi organism reproductive process GO:0044703 262 0.022
regulation of neurogenesis GO:0050767 247 0.022
cellular chemical homeostasis GO:0055082 247 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
protein complex biogenesis GO:0070271 263 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
secretion GO:0046903 307 0.022
localization of cell GO:0051674 202 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
brain development GO:0007420 247 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
positive regulation of signaling GO:0023056 270 0.021
single organism biosynthetic process GO:0044711 342 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
positive regulation of gene expression GO:0010628 244 0.021
neuron development GO:0048666 286 0.021
regulation of secretion GO:0051046 224 0.021
regulation of protein modification process GO:0031399 194 0.021
single organism reproductive process GO:0044702 297 0.021
cell cell signaling GO:0007267 335 0.021
positive regulation of cell development GO:0010720 176 0.021
regulation of phosphorylation GO:0042325 248 0.021
multicellular organism reproduction GO:0032504 233 0.021
ion homeostasis GO:0050801 212 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
organic substance catabolic process GO:1901575 316 0.020
response to peptide hormone GO:0043434 278 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
cation homeostasis GO:0055080 195 0.020
regulation of neuron differentiation GO:0045664 208 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.020
response to nutrient GO:0007584 248 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
regulation of cell proliferation GO:0042127 359 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
ras protein signal transduction GO:0007265 29 0.020
organelle organization GO:0006996 266 0.020
positive regulation of molecular function GO:0044093 230 0.020
response to growth factor GO:0070848 189 0.020
cell migration GO:0016477 197 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to stress GO:0033554 269 0.019
reproduction GO:0000003 245 0.019
protein oligomerization GO:0051259 191 0.019
nitrogen compound transport GO:0071705 229 0.019
positive regulation of cell communication GO:0010647 271 0.019
cellular catabolic process GO:0044248 295 0.019
locomotion GO:0040011 237 0.019
cell motility GO:0048870 202 0.019
response to peptide GO:1901652 292 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.019
immune system process GO:0002376 204 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
cellular ion homeostasis GO:0006873 184 0.019
nucleotide metabolic process GO:0009117 279 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
defense response GO:0006952 194 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
cellular cation homeostasis GO:0030003 180 0.018
regulation of cellular localization GO:0060341 263 0.018
metal ion homeostasis GO:0055065 186 0.018
single organism catabolic process GO:0044712 283 0.018
aging GO:0007568 241 0.018
negative regulation of cell communication GO:0010648 158 0.018
neurological system process GO:0050877 219 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
response to ethanol GO:0045471 162 0.018
purine containing compound metabolic process GO:0072521 253 0.018
response to biotic stimulus GO:0009607 226 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
negative regulation of innate immune response GO:0045824 4 0.018
regulation of ion transport GO:0043269 245 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
positive regulation of nervous system development GO:0051962 178 0.018
secretion by cell GO:0032940 248 0.018
response to decreased oxygen levels GO:0036293 237 0.017
anion transport GO:0006820 178 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
response to cytokine GO:0034097 215 0.017
negative regulation of signaling GO:0023057 157 0.017
cellular lipid metabolic process GO:0044255 208 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
regulation of secretion by cell GO:1903530 208 0.017
metal ion transport GO:0030001 289 0.017
lipid metabolic process GO:0006629 283 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
response to oxidative stress GO:0006979 186 0.017
negative regulation of gene expression GO:0010629 199 0.017
regulation of hormone levels GO:0010817 187 0.017
regulation of locomotion GO:0040012 148 0.017
response to metal ion GO:0010038 253 0.017
response to toxic substance GO:0009636 133 0.017
regulation of cell projection organization GO:0031344 175 0.017
response to hypoxia GO:0001666 231 0.017
cellular response to organonitrogen compound GO:0071417 197 0.016
regulation of neuron projection development GO:0010975 161 0.016
calcium ion homeostasis GO:0055074 162 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
tissue development GO:0009888 252 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
cellular response to lipid GO:0071396 201 0.016
head development GO:0060322 247 0.016
response to oxygen levels GO:0070482 265 0.016
positive regulation of cell death GO:0010942 184 0.016
divalent inorganic cation transport GO:0072511 134 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
response to ketone GO:1901654 182 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
immune response GO:0006955 104 0.016
positive regulation of rna metabolic process GO:0051254 203 0.015
negative regulation of cell death GO:0060548 229 0.015
response to wounding GO:0009611 254 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
behavior GO:0007610 205 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
hormone transport GO:0009914 121 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
positive regulation of signal transduction GO:0009967 175 0.015
anterior posterior pattern specification GO:0009952 1 0.015
response to other organism GO:0051707 220 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
sexual reproduction GO:0019953 148 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of system process GO:0044057 208 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of transport GO:0051050 245 0.014
response to bacterium GO:0009617 200 0.014
proteolysis GO:0006508 175 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
response to carbohydrate GO:0009743 183 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
response to estrogen GO:0043627 232 0.014
response to external biotic stimulus GO:0043207 221 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of response to stress GO:0080134 126 0.014
blood circulation GO:0008015 183 0.014
regulation of membrane potential GO:0042391 110 0.014
synaptic transmission GO:0007268 235 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
peptidyl amino acid modification GO:0018193 126 0.014
mapk cascade GO:0000165 140 0.014
negative regulation of transport GO:0051051 136 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
regulation of cell motility GO:2000145 131 0.014
heterocycle catabolic process GO:0046700 167 0.014
negative regulation of developmental process GO:0051093 125 0.014
single organism organelle organization GO:1902589 180 0.014
signal release GO:0023061 145 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
oxidation reduction process GO:0055114 304 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
inflammatory response GO:0006954 150 0.013
gastrulation GO:0007369 2 0.013
divalent metal ion transport GO:0070838 132 0.013
gamete generation GO:0007276 124 0.013
heart morphogenesis GO:0003007 3 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of transferase activity GO:0051338 123 0.013
circulatory system process GO:0003013 183 0.013
intracellular transport GO:0046907 185 0.013
regulation of hydrolase activity GO:0051336 143 0.013
response to acid chemical GO:0001101 222 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
growth GO:0040007 165 0.013
regulation of cell migration GO:0030334 128 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
calcium ion transport GO:0006816 131 0.013
response to alkaloid GO:0043279 132 0.013
leukocyte cell cell adhesion GO:0007159 4 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
axis specification GO:0009798 4 0.013
biological adhesion GO:0022610 110 0.013
cellular response to peptide GO:1901653 133 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
developmental process involved in reproduction GO:0003006 159 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
rhythmic process GO:0048511 156 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regeneration GO:0031099 163 0.012
nucleoside metabolic process GO:0009116 179 0.012
action potential GO:0001508 54 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
response to glucocorticoid GO:0051384 223 0.012
response to vitamin GO:0033273 131 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
reproductive system development GO:0061458 128 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of catabolic process GO:0009894 113 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of immune system process GO:0002682 123 0.012
response to monosaccharide GO:0034284 159 0.012
regulation of kinase activity GO:0043549 117 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
response to lipopolysaccharide GO:0032496 191 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
sex differentiation GO:0007548 113 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
hormone secretion GO:0046879 115 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
aromatic compound catabolic process GO:0019439 168 0.012
cellular response to external stimulus GO:0071496 118 0.011
sensory perception GO:0007600 101 0.011
organic anion transport GO:0015711 132 0.011
cell adhesion GO:0007155 110 0.011
response to reactive oxygen species GO:0000302 120 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
response to glucose GO:0009749 136 0.011
macromolecule localization GO:0033036 252 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
response to corticosteroid GO:0031960 235 0.011
cell type specific apoptotic process GO:0097285 134 0.011
response to radiation GO:0009314 137 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
response to hexose GO:0009746 144 0.011
vesicle mediated transport GO:0016192 181 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
muscle system process GO:0003012 115 0.011
cell growth GO:0016049 104 0.011
purine containing compound catabolic process GO:0072523 138 0.011
circulatory system development GO:0072359 134 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
organophosphate catabolic process GO:0046434 148 0.011
eye morphogenesis GO:0048592 4 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
gland development GO:0048732 155 0.011
regulation of hormone secretion GO:0046883 106 0.011
chromosome segregation GO:0007059 2 0.011
regulation of cell growth GO:0001558 85 0.011
organic acid transport GO:0015849 116 0.011
development of primary sexual characteristics GO:0045137 107 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
gliogenesis GO:0042063 93 0.011
gonad development GO:0008406 104 0.011
response to mechanical stimulus GO:0009612 134 0.011
cardiovascular system development GO:0072358 134 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
neuron projection morphogenesis GO:0048812 122 0.011
actin filament based process GO:0030029 86 0.011
response to insulin GO:0032868 133 0.010
regulation of response to external stimulus GO:0032101 106 0.010
male gamete generation GO:0048232 99 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
multi multicellular organism process GO:0044706 138 0.010
salivary gland development GO:0007431 3 0.010
nucleotide catabolic process GO:0009166 139 0.010
positive regulation of secretion GO:0051047 140 0.010
regulation of protein kinase activity GO:0045859 105 0.010
cytokine biosynthetic process GO:0042089 3 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
response to estradiol GO:0032355 164 0.010
amide transport GO:0042886 105 0.010
cell morphogenesis GO:0000902 142 0.010
embryonic pattern specification GO:0009880 1 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
carbohydrate metabolic process GO:0005975 130 0.010
cell part morphogenesis GO:0032990 123 0.010
sequestering of calcium ion GO:0051208 8 0.010
protein localization GO:0008104 191 0.010
sequestering of metal ion GO:0051238 9 0.010
cytoplasmic transport GO:0016482 115 0.010

Il21r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.011
musculoskeletal system disease DOID:17 0 0.011