Rattus norvegicus

0 known processes

Sox8

SRY (sex determining region Y)-box 8

Sox8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.055
oxoacid metabolic process GO:0043436 290 0.047
response to nutrient levels GO:0031667 370 0.047
response to inorganic substance GO:0010035 377 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
Human Rat
transmembrane transport GO:0055085 412 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
cation transport GO:0006812 382 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
Human Rat
response to extracellular stimulus GO:0009991 380 0.039
regulation of apoptotic process GO:0042981 335 0.039
programmed cell death GO:0012501 392 0.039
rna metabolic process GO:0016070 406 0.038
Human Rat
central nervous system development GO:0007417 311 0.038
Rat
transcription dna templated GO:0006351 377 0.038
Human Rat
anatomical structure morphogenesis GO:0009653 298 0.038
apoptotic process GO:0006915 381 0.038
neuron differentiation GO:0030182 368 0.038
Rat
regulation of molecular function GO:0065009 398 0.037
Rat
cellular amino acid metabolic process GO:0006520 107 0.036
cellular response to endogenous stimulus GO:0071495 377 0.035
cellular component biogenesis GO:0044085 368 0.034
cellular response to oxygen containing compound GO:1901701 386 0.033
cellular component assembly GO:0022607 360 0.033
ion transmembrane transport GO:0034220 365 0.033
macromolecular complex assembly GO:0065003 273 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cellular ketone metabolic process GO:0042180 51 0.032
protein phosphorylation GO:0006468 345 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
Human Rat
chemical homeostasis GO:0048878 292 0.032
rna biosynthetic process GO:0032774 380 0.031
Human Rat
amine metabolic process GO:0009308 38 0.031
regulation of rna metabolic process GO:0051252 391 0.031
Human Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
intracellular signal transduction GO:0035556 314 0.030
brain development GO:0007420 247 0.030
cellular amine metabolic process GO:0044106 38 0.030
neuron projection development GO:0031175 273 0.030
nucleic acid templated transcription GO:0097659 379 0.030
Human Rat
protein complex biogenesis GO:0070271 263 0.030
regulation of programmed cell death GO:0043067 341 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.029
response to nutrient GO:0007584 248 0.029
metal ion transport GO:0030001 289 0.029
cellular component movement GO:0006928 248 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
cell cell signaling GO:0007267 335 0.028
homeostatic process GO:0042592 331 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of transcription dna templated GO:0006355 374 0.028
Human Rat
protein complex subunit organization GO:0071822 302 0.028
secretion GO:0046903 307 0.027
head development GO:0060322 247 0.027
cell projection organization GO:0030030 302 0.027
regulation of cell proliferation GO:0042127 359 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
regulation of cell differentiation GO:0045595 320 0.027
reproductive process GO:0022414 372 0.026
Fly
regulation of cellular component organization GO:0051128 368 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
regulation of cell development GO:0060284 263 0.026
cellular chemical homeostasis GO:0055082 247 0.026
response to metal ion GO:0010038 253 0.026
catabolic process GO:0009056 351 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
single organism reproductive process GO:0044702 297 0.026
Fly
protein complex assembly GO:0006461 263 0.025
cellular response to stress GO:0033554 269 0.025
organophosphate metabolic process GO:0019637 370 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
Human Rat
response to decreased oxygen levels GO:0036293 237 0.025
negative regulation of cell death GO:0060548 229 0.025
response to oxygen levels GO:0070482 265 0.025
regulation of nervous system development GO:0051960 264 0.025
multi organism reproductive process GO:0044703 262 0.025
nitrogen compound transport GO:0071705 229 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.024
single organism biosynthetic process GO:0044711 342 0.024
lipid metabolic process GO:0006629 283 0.024
negative regulation of metabolic process GO:0009892 331 0.024
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.024
positive regulation of developmental process GO:0051094 283 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
Human Rat
multicellular organismal reproductive process GO:0048609 233 0.023
organic substance catabolic process GO:1901575 316 0.023
nucleotide metabolic process GO:0009117 279 0.023
cellular catabolic process GO:0044248 295 0.023
neuron development GO:0048666 286 0.023
reproduction GO:0000003 245 0.023
response to hypoxia GO:0001666 231 0.023
regulation of catalytic activity GO:0050790 304 0.023
single organism catabolic process GO:0044712 283 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
cellular homeostasis GO:0019725 252 0.023
aging GO:0007568 241 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
purine containing compound metabolic process GO:0072521 253 0.022
synaptic transmission GO:0007268 235 0.022
response to growth factor GO:0070848 189 0.022
positive regulation of molecular function GO:0044093 230 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
Human Rat
ion homeostasis GO:0050801 212 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
Human Rat
response to peptide GO:1901652 292 0.021
positive regulation of signaling GO:0023056 270 0.021
response to corticosteroid GO:0031960 235 0.021
response to acid chemical GO:0001101 222 0.021
secretion by cell GO:0032940 248 0.021
multicellular organism reproduction GO:0032504 233 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
positive regulation of gene expression GO:0010628 244 0.021
Human Rat
tissue development GO:0009888 252 0.021
protein oligomerization GO:0051259 191 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
regulation of cellular localization GO:0060341 263 0.021
regulation of protein metabolic process GO:0051246 289 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
Human Rat
inorganic ion transmembrane transport GO:0098660 229 0.021
regulation of neurogenesis GO:0050767 247 0.021
response to carbohydrate GO:0009743 183 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
response to estrogen GO:0043627 232 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of phosphorylation GO:0042325 248 0.020
locomotion GO:0040011 237 0.020
regulation of secretion GO:0051046 224 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
response to peptide hormone GO:0043434 278 0.020
ribonucleoside metabolic process GO:0009119 174 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
Rat
response to glucocorticoid GO:0051384 223 0.019
cation transmembrane transport GO:0098655 263 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
Human Rat
regulation of cell projection organization GO:0031344 175 0.019
regulation of membrane potential GO:0042391 110 0.019
negative regulation of cell communication GO:0010648 158 0.019
regulation of system process GO:0044057 208 0.019
response to monosaccharide GO:0034284 159 0.019
response to alkaloid GO:0043279 132 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of cell communication GO:0010647 271 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cation homeostasis GO:0055080 195 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
cellular ion homeostasis GO:0006873 184 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
regulation of neuron differentiation GO:0045664 208 0.018
regulation of ion transport GO:0043269 245 0.018
circulatory system process GO:0003013 183 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
Human Rat
ribonucleotide metabolic process GO:0009259 231 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
Human Rat
neurological system process GO:0050877 219 0.018
ras protein signal transduction GO:0007265 29 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
Human Rat
cellular cation homeostasis GO:0030003 180 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
anterior posterior pattern specification GO:0009952 1 0.018
regulation of synaptic transmission GO:0050804 141 0.017
rhythmic process GO:0048511 156 0.017
calcium ion transport GO:0006816 131 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
cellular response to lipid GO:0071396 201 0.017
positive regulation of cell development GO:0010720 176 0.017
organelle organization GO:0006996 266 0.017
negative regulation of gene expression GO:0010629 199 0.017
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.017
regulation of secretion by cell GO:1903530 208 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
oxidation reduction process GO:0055114 304 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
localization of cell GO:0051674 202 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
Rat
heterocycle catabolic process GO:0046700 167 0.017
regeneration GO:0031099 163 0.017
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of hormone levels GO:0010817 187 0.016
regulation of anatomical structure size GO:0090066 135 0.016
cell migration GO:0016477 197 0.016
reproductive system development GO:0061458 128 0.016
Fly
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
Human Rat
response to hexose GO:0009746 144 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
anion transport GO:0006820 178 0.016
cell motility GO:0048870 202 0.016
response to bacterium GO:0009617 200 0.016
nucleoside metabolic process GO:0009116 179 0.016
calcium ion homeostasis GO:0055074 162 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
heart morphogenesis GO:0003007 3 0.016
response to ethanol GO:0045471 162 0.016
regulation of protein modification process GO:0031399 194 0.016
response to ketone GO:1901654 182 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
axis specification GO:0009798 4 0.016
divalent inorganic cation transport GO:0072511 134 0.016
macromolecule localization GO:0033036 252 0.016
response to vitamin GO:0033273 131 0.016
metal ion homeostasis GO:0055065 186 0.016
cellular component morphogenesis GO:0032989 155 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
sexual reproduction GO:0019953 148 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
defense response GO:0006952 194 0.015
proteolysis GO:0006508 175 0.015
divalent metal ion transport GO:0070838 132 0.015
circulatory system development GO:0072359 134 0.015
positive regulation of transport GO:0051050 245 0.015
coenzyme metabolic process GO:0006732 86 0.015
response to lipopolysaccharide GO:0032496 191 0.015
growth GO:0040007 165 0.015
developmental process involved in reproduction GO:0003006 159 0.015
Fly
intracellular transport GO:0046907 185 0.015
regulation of mapk cascade GO:0043408 116 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
transmission of nerve impulse GO:0019226 42 0.015
cell projection morphogenesis GO:0048858 123 0.015
blood circulation GO:0008015 183 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
response to oxidative stress GO:0006979 186 0.015
multicellular organismal signaling GO:0035637 44 0.015
response to wounding GO:0009611 254 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Rat
cardiovascular system development GO:0072358 134 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
Rat
response to biotic stimulus GO:0009607 226 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
Human Rat
positive regulation of cell death GO:0010942 184 0.015
peptidyl amino acid modification GO:0018193 126 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
cofactor metabolic process GO:0051186 95 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
positive regulation of nervous system development GO:0051962 178 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
Rat
response to glucose GO:0009749 136 0.014
carbohydrate metabolic process GO:0005975 130 0.014
single organism organelle organization GO:1902589 180 0.014
regulation of cellular component movement GO:0051270 150 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
single organism intracellular transport GO:1902582 166 0.014
negative regulation of signaling GO:0023057 157 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
signal release GO:0023061 145 0.014
cell morphogenesis GO:0000902 142 0.014
action potential GO:0001508 54 0.014
response to other organism GO:0051707 220 0.014
behavior GO:0007610 205 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
neuron projection morphogenesis GO:0048812 122 0.014
eye morphogenesis GO:0048592 4 0.014
muscle system process GO:0003012 115 0.014
forebrain development GO:0030900 98 0.014
response to cytokine GO:0034097 215 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
negative regulation of developmental process GO:0051093 125 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
response to toxic substance GO:0009636 133 0.013
organic anion transport GO:0015711 132 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
positive regulation of protein modification process GO:0031401 142 0.013
regulation of hydrolase activity GO:0051336 143 0.013
response to estradiol GO:0032355 164 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
gastrulation GO:0007369 2 0.013
gland development GO:0048732 155 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
Rat
regulation of locomotion GO:0040012 148 0.013
establishment of tissue polarity GO:0007164 2 0.013
regulation of neuron projection development GO:0010975 161 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
response to external biotic stimulus GO:0043207 221 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
cell growth GO:0016049 104 0.013
actin filament based process GO:0030029 86 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
inflammatory response GO:0006954 150 0.013
response to amino acid GO:0043200 75 0.013
limb morphogenesis GO:0035108 4 0.013
positive regulation of neuron differentiation GO:0045666 126 0.012
neuronal action potential GO:0019228 35 0.012
gamete generation GO:0007276 124 0.012
negative regulation of transport GO:0051051 136 0.012
aromatic compound catabolic process GO:0019439 168 0.012
reproductive structure development GO:0048608 128 0.012
Fly
purine containing compound catabolic process GO:0072523 138 0.012
multi multicellular organism process GO:0044706 138 0.012
cellular response to peptide GO:1901653 133 0.012
positive regulation of signal transduction GO:0009967 175 0.012
development of primary sexual characteristics GO:0045137 107 0.012
Fly
signal transduction by phosphorylation GO:0023014 144 0.012
hormone secretion GO:0046879 115 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cell type specific apoptotic process GO:0097285 134 0.012
epithelium development GO:0060429 96 0.012
cellular lipid metabolic process GO:0044255 208 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
response to purine containing compound GO:0014074 126 0.012
axon development GO:0061564 96 0.012
positive regulation of ion transport GO:0043270 94 0.012
sequestering of metal ion GO:0051238 9 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of cell motility GO:2000145 131 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of transcription dna templated GO:0045892 116 0.011
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
Rat
organic acid biosynthetic process GO:0016053 83 0.011
regulation of metal ion transport GO:0010959 118 0.011
mesoderm development GO:0007498 2 0.011
vascular process in circulatory system GO:0003018 96 0.011
regulation of blood circulation GO:1903522 110 0.011
hormone transport GO:0009914 121 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
cellular response to alcohol GO:0097306 87 0.011
female pregnancy GO:0007565 122 0.011
peptide secretion GO:0002790 86 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
sequestering of calcium ion GO:0051208 8 0.011
response to radiation GO:0009314 137 0.011
mapk cascade GO:0000165 140 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
cell adhesion GO:0007155 110 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
Rat
regulation of neuron death GO:1901214 115 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of protein kinase activity GO:0045859 105 0.011
single organism behavior GO:0044708 130 0.011
vesicle mediated transport GO:0016192 181 0.011
protein localization GO:0008104 191 0.011
chromosome segregation GO:0007059 2 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
muscle contraction GO:0006936 88 0.011
dna metabolic process GO:0006259 96 0.011
cytoplasmic transport GO:0016482 115 0.011
negative regulation of molecular function GO:0044092 133 0.011
Rat
negative regulation of innate immune response GO:0045824 4 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of cell migration GO:0030334 128 0.011
positive regulation of secretion GO:0051047 140 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
salivary gland development GO:0007431 3 0.011
appendage morphogenesis GO:0035107 4 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
nucleoside catabolic process GO:0009164 126 0.011
gonad development GO:0008406 104 0.011
Fly
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of homeostatic process GO:0032844 101 0.011
organic acid transport GO:0015849 116 0.011
nucleotide catabolic process GO:0009166 139 0.011
lipid biosynthetic process GO:0008610 128 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of response to stress GO:0080134 126 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
organophosphate catabolic process GO:0046434 148 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
Rat
regulation of tube size GO:0035150 89 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
amide transport GO:0042886 105 0.010
organ regeneration GO:0031100 101 0.010
protein homooligomerization GO:0051260 91 0.010
embryonic pattern specification GO:0009880 1 0.010
cardiac chamber development GO:0003205 1 0.010
regulation of cell growth GO:0001558 85 0.010
small molecule biosynthetic process GO:0044283 124 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
developmental growth GO:0048589 100 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of hormone secretion GO:0046883 106 0.010
carboxylic acid transport GO:0046942 115 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
lipid storage GO:0019915 1 0.010
heart contraction GO:0060047 57 0.010
peptide hormone secretion GO:0030072 84 0.010
tube development GO:0035295 89 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
regulation of blood vessel size GO:0050880 89 0.010

Sox8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
sensory system disease DOID:0050155 0 0.016
disease of metabolism DOID:0014667 0 0.014
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
inherited metabolic disorder DOID:655 0 0.011
disease of cellular proliferation DOID:14566 0 0.010