Rattus norvegicus

0 known processes

Cables1

Cdk5 and Abl enzyme substrate 1

Cables1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
carboxylic acid metabolic process GO:0019752 289 0.070
oxoacid metabolic process GO:0043436 290 0.069
neuron differentiation GO:0030182 368 0.068
organic acid metabolic process GO:0006082 292 0.062
regulation of phosphorus metabolic process GO:0051174 349 0.061
single organism catabolic process GO:0044712 283 0.058
cell projection organization GO:0030030 302 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
catabolic process GO:0009056 351 0.053
organophosphate metabolic process GO:0019637 370 0.053
transcription dna templated GO:0006351 377 0.050
positive regulation of rna metabolic process GO:0051254 203 0.049
nucleic acid templated transcription GO:0097659 379 0.049
regulation of multicellular organismal development GO:2000026 376 0.048
head development GO:0060322 247 0.048
response to wounding GO:0009611 254 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
organic substance catabolic process GO:1901575 316 0.044
regulation of molecular function GO:0065009 398 0.044
regulation of transcription dna templated GO:0006355 374 0.043
protein phosphorylation GO:0006468 345 0.043
rna metabolic process GO:0016070 406 0.042
central nervous system development GO:0007417 311 0.041
intracellular signal transduction GO:0035556 314 0.039
regulation of rna biosynthetic process GO:2001141 381 0.039
regulation of cellular component organization GO:0051128 368 0.039
cellular component biogenesis GO:0044085 368 0.038
regulation of rna metabolic process GO:0051252 391 0.038
cellular response to endogenous stimulus GO:0071495 377 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.038
regulation of neurogenesis GO:0050767 247 0.037
regulation of nervous system development GO:0051960 264 0.037
positive regulation of gene expression GO:0010628 244 0.037
regulation of catalytic activity GO:0050790 304 0.037
neuron projection morphogenesis GO:0048812 122 0.037
amine metabolic process GO:0009308 38 0.037
programmed cell death GO:0012501 392 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
neuron projection development GO:0031175 273 0.036
cell cell signaling GO:0007267 335 0.036
purine nucleotide catabolic process GO:0006195 136 0.036
homeostatic process GO:0042592 331 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
response to peptide GO:1901652 292 0.035
organophosphate catabolic process GO:0046434 148 0.035
cellular ketone metabolic process GO:0042180 51 0.035
cation transport GO:0006812 382 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
response to nutrient levels GO:0031667 370 0.035
chemical homeostasis GO:0048878 292 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
purine containing compound metabolic process GO:0072521 253 0.034
locomotion GO:0040011 237 0.034
cellular lipid metabolic process GO:0044255 208 0.034
nucleotide metabolic process GO:0009117 279 0.033
purine containing compound catabolic process GO:0072523 138 0.033
protein complex subunit organization GO:0071822 302 0.033
regulation of cell differentiation GO:0045595 320 0.032
cellular response to hormone stimulus GO:0032870 247 0.032
regulation of signal transduction GO:0009966 318 0.032
cellular component assembly GO:0022607 360 0.032
apoptotic process GO:0006915 381 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
response to peptide hormone GO:0043434 278 0.030
cellular amine metabolic process GO:0044106 38 0.030
aromatic compound catabolic process GO:0019439 168 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
regulation of protein metabolic process GO:0051246 289 0.029
lipid metabolic process GO:0006629 283 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
cellular catabolic process GO:0044248 295 0.029
regulation of cell development GO:0060284 263 0.029
cellular component movement GO:0006928 248 0.029
purine nucleotide metabolic process GO:0006163 229 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
purine ribonucleotide metabolic process GO:0009150 227 0.028
localization of cell GO:0051674 202 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
nucleotide catabolic process GO:0009166 139 0.028
regulation of cell proliferation GO:0042127 359 0.028
response to inorganic substance GO:0010035 377 0.028
anion transport GO:0006820 178 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
response to extracellular stimulus GO:0009991 380 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of neuron differentiation GO:0045664 208 0.027
neurological system process GO:0050877 219 0.027
rna biosynthetic process GO:0032774 380 0.027
regulation of apoptotic process GO:0042981 335 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
epithelium development GO:0060429 96 0.027
positive regulation of nervous system development GO:0051962 178 0.027
protein oligomerization GO:0051259 191 0.027
organonitrogen compound catabolic process GO:1901565 179 0.026
cell part morphogenesis GO:0032990 123 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
aging GO:0007568 241 0.026
negative regulation of metabolic process GO:0009892 331 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
purine ribonucleotide catabolic process GO:0009154 136 0.025
regulation of membrane potential GO:0042391 110 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
regulation of phosphorylation GO:0042325 248 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
neuron development GO:0048666 286 0.024
positive regulation of molecular function GO:0044093 230 0.024
nucleoside phosphate catabolic process GO:1901292 140 0.024
regulation of neuron projection development GO:0010975 161 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
ras protein signal transduction GO:0007265 29 0.024
single organism biosynthetic process GO:0044711 342 0.023
cellular response to stress GO:0033554 269 0.023
response to oxygen levels GO:0070482 265 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
metal ion transport GO:0030001 289 0.023
protein complex biogenesis GO:0070271 263 0.023
tissue development GO:0009888 252 0.023
forebrain development GO:0030900 98 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
nucleoside metabolic process GO:0009116 179 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
reproductive process GO:0022414 372 0.022
transmembrane transport GO:0055085 412 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
positive regulation of developmental process GO:0051094 283 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
intracellular transport GO:0046907 185 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
nucleoside catabolic process GO:0009164 126 0.021
negative regulation of signaling GO:0023057 157 0.021
brain development GO:0007420 247 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
cell projection morphogenesis GO:0048858 123 0.021
response to growth factor GO:0070848 189 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
negative regulation of developmental process GO:0051093 125 0.021
protein complex assembly GO:0006461 263 0.021
positive regulation of cell projection organization GO:0031346 111 0.020
vesicle mediated transport GO:0016192 181 0.020
gland development GO:0048732 155 0.020
lipid biosynthetic process GO:0008610 128 0.020
action potential GO:0001508 54 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
secretion GO:0046903 307 0.020
response to purine containing compound GO:0014074 126 0.020
response to acid chemical GO:0001101 222 0.020
purine nucleoside catabolic process GO:0006152 124 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
negative regulation of cell development GO:0010721 82 0.020
positive regulation of cell communication GO:0010647 271 0.020
positive regulation of signaling GO:0023056 270 0.020
regulation of canonical wnt signaling pathway GO:0060828 4 0.020
cellular component morphogenesis GO:0032989 155 0.019
regulation of hydrolase activity GO:0051336 143 0.019
macromolecular complex assembly GO:0065003 273 0.019
response to monosaccharide GO:0034284 159 0.019
multi organism reproductive process GO:0044703 262 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
negative regulation of cell communication GO:0010648 158 0.019
regulation of locomotion GO:0040012 148 0.019
carbohydrate metabolic process GO:0005975 130 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
positive regulation of cell development GO:0010720 176 0.019
cellular homeostasis GO:0019725 252 0.019
response to camp GO:0051591 91 0.019
oxidation reduction process GO:0055114 304 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
ion transmembrane transport GO:0034220 365 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
regulation of cell migration GO:0030334 128 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
organelle organization GO:0006996 266 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
heterocycle catabolic process GO:0046700 167 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
response to hypoxia GO:0001666 231 0.018
cardiovascular system development GO:0072358 134 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
gastrulation GO:0007369 2 0.018
response to cytokine GO:0034097 215 0.018
cellular response to lipid GO:0071396 201 0.018
salivary gland development GO:0007431 3 0.018
single organism intracellular transport GO:1902582 166 0.018
response to biotic stimulus GO:0009607 226 0.018
regulation of protein modification process GO:0031399 194 0.018
cellular response to peptide GO:1901653 133 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of response to stress GO:0080134 126 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
response to decreased oxygen levels GO:0036293 237 0.017
regeneration GO:0031099 163 0.017
cell morphogenesis GO:0000902 142 0.017
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
response to carbohydrate GO:0009743 183 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
regulation of programmed cell death GO:0043067 341 0.017
cellular macromolecule localization GO:0070727 122 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
multicellular organismal signaling GO:0035637 44 0.017
response to other organism GO:0051707 220 0.017
response to metal ion GO:0010038 253 0.017
response to glucocorticoid GO:0051384 223 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
positive regulation of cell death GO:0010942 184 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
cellular chemical homeostasis GO:0055082 247 0.016
multicellular organism reproduction GO:0032504 233 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of cell motility GO:2000145 131 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
negative regulation of nervous system development GO:0051961 79 0.016
transmission of nerve impulse GO:0019226 42 0.016
response to alkaloid GO:0043279 132 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
regulation of cell projection organization GO:0031344 175 0.016
cardiac conduction GO:0061337 2 0.015
macromolecule localization GO:0033036 252 0.015
hormone transport GO:0009914 121 0.015
response to hexose GO:0009746 144 0.015
response to mechanical stimulus GO:0009612 134 0.015
gtp metabolic process GO:0046039 72 0.015
cognition GO:0050890 92 0.015
negative regulation of molecular function GO:0044092 133 0.015
regulation of synaptic transmission GO:0050804 141 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
response to external biotic stimulus GO:0043207 221 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
signal release GO:0023061 145 0.015
steroid metabolic process GO:0008202 73 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
reproduction GO:0000003 245 0.015
regulation of hormone levels GO:0010817 187 0.014
positive regulation of neuron migration GO:2001224 2 0.014
cell migration GO:0016477 197 0.014
circulatory system development GO:0072359 134 0.014
regulation of catabolic process GO:0009894 113 0.014
positive regulation of protein modification process GO:0031401 142 0.014
neuronal action potential GO:0019228 35 0.014
reproductive structure development GO:0048608 128 0.014
cellular protein localization GO:0034613 122 0.014
response to insulin GO:0032868 133 0.014
protein localization GO:0008104 191 0.014
sexual reproduction GO:0019953 148 0.014
small molecule biosynthetic process GO:0044283 124 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
regulation of hormone secretion GO:0046883 106 0.014
amide transport GO:0042886 105 0.014
female pregnancy GO:0007565 122 0.014
cellular response to external stimulus GO:0071496 118 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
regulation of ion transport GO:0043269 245 0.014
mesoderm development GO:0007498 2 0.014
axon development GO:0061564 96 0.014
regulation of system process GO:0044057 208 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
learning or memory GO:0007611 90 0.013
appendage morphogenesis GO:0035107 4 0.013
insulin like growth factor receptor signaling pathway GO:0048009 3 0.013
developmental process involved in reproduction GO:0003006 159 0.013
protein heterooligomerization GO:0051291 89 0.013
nitrogen compound transport GO:0071705 229 0.013
reproductive system development GO:0061458 128 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
calcium ion homeostasis GO:0055074 162 0.013
single organism behavior GO:0044708 130 0.013
single organism reproductive process GO:0044702 297 0.013
positive regulation of signal transduction GO:0009967 175 0.013
response to transition metal nanoparticle GO:1990267 122 0.012
cell motility GO:0048870 202 0.012
axis specification GO:0009798 4 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
behavior GO:0007610 205 0.012
proteolysis GO:0006508 175 0.012
response to hydrogen peroxide GO:0042542 89 0.012
organ morphogenesis GO:0009887 75 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
response to reactive oxygen species GO:0000302 120 0.012
response to nutrient GO:0007584 248 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
rho protein signal transduction GO:0007266 11 0.012
sensory perception GO:0007600 101 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
growth GO:0040007 165 0.012
metal ion homeostasis GO:0055065 186 0.012
response to corticosteroid GO:0031960 235 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
regulation of body fluid levels GO:0050878 90 0.012
hormone secretion GO:0046879 115 0.012
heart morphogenesis GO:0003007 3 0.012
protein autophosphorylation GO:0046777 66 0.012
regulation of peptide transport GO:0090087 87 0.012
response to toxic substance GO:0009636 133 0.012
regulation of secretion GO:0051046 224 0.012
anterior posterior pattern specification GO:0009952 1 0.012
hormone metabolic process GO:0042445 69 0.012
gtp catabolic process GO:0006184 71 0.012
alcohol metabolic process GO:0006066 77 0.012
dendrite development GO:0016358 72 0.011
establishment of protein localization GO:0045184 141 0.011
myelination GO:0042552 39 0.011
regulation of homeostatic process GO:0032844 101 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
response to oxidative stress GO:0006979 186 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
cell growth GO:0016049 104 0.011
protein transport GO:0015031 132 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.011
response to estrogen GO:0043627 232 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
organic acid biosynthetic process GO:0016053 83 0.011
regulation of protein kinase activity GO:0045859 105 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
synaptic transmission GO:0007268 235 0.011
regulation of anatomical structure size GO:0090066 135 0.011
circulatory system process GO:0003013 183 0.011
cell cycle checkpoint GO:0000075 2 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.011
fatty acid metabolic process GO:0006631 99 0.011
negative regulation of transport GO:0051051 136 0.011
peptide transport GO:0015833 97 0.011
cell cycle GO:0007049 101 0.011
positive regulation of catabolic process GO:0009896 78 0.011
single organism membrane organization GO:0044802 74 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
regulation of transferase activity GO:0051338 123 0.011
response to bacterium GO:0009617 200 0.011
regulation of cellular localization GO:0060341 263 0.011
gliogenesis GO:0042063 93 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.011
mapk cascade GO:0000165 140 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
response to estradiol GO:0032355 164 0.010
telencephalon development GO:0021537 62 0.010
tube formation GO:0035148 3 0.010
cation homeostasis GO:0055080 195 0.010
embryonic pattern specification GO:0009880 1 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
adult locomotory behavior GO:0008344 4 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
embryonic skeletal system development GO:0048706 3 0.010
gamete generation GO:0007276 124 0.010
organic hydroxy compound transport GO:0015850 77 0.010
limb morphogenesis GO:0035108 4 0.010
positive regulation of nucleotide catabolic process GO:0030813 53 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
male gamete generation GO:0048232 99 0.010
multicellular organism growth GO:0035264 1 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010

Cables1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.019
disease of metabolism DOID:0014667 0 0.019
central nervous system disease DOID:331 0 0.012