Rattus norvegicus

0 known processes

Was

Wiskott-Aldrich syndrome homolog (human)

(Aliases: WASP)

Was biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of response to stimulus GO:0048584 285 0.070
intracellular signal transduction GO:0035556 314 0.053
protein phosphorylation GO:0006468 345 0.052
regulation of signal transduction GO:0009966 318 0.045
rna biosynthetic process GO:0032774 380 0.041
cellular amino acid metabolic process GO:0006520 107 0.040
regulation of multicellular organismal development GO:2000026 376 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
response to extracellular stimulus GO:0009991 380 0.037
organophosphate metabolic process GO:0019637 370 0.037
response to bacterium GO:0009617 200 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
regulation of apoptotic process GO:0042981 335 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
immune system process GO:0002376 204 0.035
Human
transmembrane transport GO:0055085 412 0.035
central nervous system development GO:0007417 311 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
cation transport GO:0006812 382 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
multi organism reproductive process GO:0044703 262 0.033
cellular homeostasis GO:0019725 252 0.033
regulation of protein metabolic process GO:0051246 289 0.033
response to nutrient levels GO:0031667 370 0.032
positive regulation of cell communication GO:0010647 271 0.032
positive regulation of signaling GO:0023056 270 0.032
amine metabolic process GO:0009308 38 0.031
macromolecule localization GO:0033036 252 0.031
cellular component movement GO:0006928 248 0.031
Rat
cellular ion homeostasis GO:0006873 184 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
membrane organization GO:0061024 94 0.031
Rat
cation transmembrane transport GO:0098655 263 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
rna metabolic process GO:0016070 406 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
programmed cell death GO:0012501 392 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
cellular amine metabolic process GO:0044106 38 0.030
nucleotide metabolic process GO:0009117 279 0.029
cellular chemical homeostasis GO:0055082 247 0.029
regulation of cell differentiation GO:0045595 320 0.029
single organism reproductive process GO:0044702 297 0.029
response to inorganic substance GO:0010035 377 0.029
locomotion GO:0040011 237 0.028
metal ion homeostasis GO:0055065 186 0.028
regulation of transcription dna templated GO:0006355 374 0.028
apoptotic process GO:0006915 381 0.028
regulation of rna metabolic process GO:0051252 391 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
response to biotic stimulus GO:0009607 226 0.028
defense response GO:0006952 194 0.028
oxoacid metabolic process GO:0043436 290 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
response to other organism GO:0051707 220 0.027
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.027
negative regulation of metabolic process GO:0009892 331 0.027
reproductive process GO:0022414 372 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
response to external biotic stimulus GO:0043207 221 0.027
regulation of programmed cell death GO:0043067 341 0.027
regulation of molecular function GO:0065009 398 0.026
nucleic acid templated transcription GO:0097659 379 0.026
divalent inorganic cation homeostasis GO:0072507 165 0.026
organic acid metabolic process GO:0006082 292 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
transcription dna templated GO:0006351 377 0.026
ion homeostasis GO:0050801 212 0.025
cellular cation homeostasis GO:0030003 180 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
cellular ketone metabolic process GO:0042180 51 0.025
regulation of cell development GO:0060284 263 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
protein localization GO:0008104 191 0.025
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.025
response to peptide GO:1901652 292 0.025
cation homeostasis GO:0055080 195 0.025
purine containing compound metabolic process GO:0072521 253 0.025
regulation of cell proliferation GO:0042127 359 0.025
regulation of protein phosphorylation GO:0001932 183 0.024
single organism cellular localization GO:1902580 102 0.024
Rat
regulation of secretion GO:0051046 224 0.024
ion transmembrane transport GO:0034220 365 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
negative regulation of cell death GO:0060548 229 0.023
positive regulation of cell death GO:0010942 184 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
single organism biosynthetic process GO:0044711 342 0.023
response to oxidative stress GO:0006979 186 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
cellular catabolic process GO:0044248 295 0.023
positive regulation of transport GO:0051050 245 0.023
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.023
positive regulation of gene expression GO:0010628 244 0.023
response to acid chemical GO:0001101 222 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
positive regulation of signal transduction GO:0009967 175 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
homeostatic process GO:0042592 331 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
regulation of phosphorylation GO:0042325 248 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
reproduction GO:0000003 245 0.021
chemical homeostasis GO:0048878 292 0.021
catabolic process GO:0009056 351 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
regulation of protein modification process GO:0031399 194 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
tissue development GO:0009888 252 0.021
response to wounding GO:0009611 254 0.021
protein complex assembly GO:0006461 263 0.021
aging GO:0007568 241 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
regulation of immune system process GO:0002682 123 0.021
cellular component assembly GO:0022607 360 0.021
Rat
cell projection organization GO:0030030 302 0.021
Rat
response to peptide hormone GO:0043434 278 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
calcium ion homeostasis GO:0055074 162 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
response to hypoxia GO:0001666 231 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
negative regulation of innate immune response GO:0045824 4 0.020
regulation of nervous system development GO:0051960 264 0.020
cellular component biogenesis GO:0044085 368 0.020
Rat
blood circulation GO:0008015 183 0.020
single organism intracellular transport GO:1902582 166 0.020
neuron differentiation GO:0030182 368 0.020
single organism catabolic process GO:0044712 283 0.020
positive regulation of developmental process GO:0051094 283 0.020
multicellular organism reproduction GO:0032504 233 0.020
single organism membrane organization GO:0044802 74 0.020
Rat
response to nutrient GO:0007584 248 0.020
neurological system process GO:0050877 219 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
cell cell signaling GO:0007267 335 0.020
protein complex subunit organization GO:0071822 302 0.020
response to metal ion GO:0010038 253 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
protein complex biogenesis GO:0070271 263 0.019
nitrogen compound transport GO:0071705 229 0.019
immune response GO:0006955 104 0.019
Human
positive regulation of cell proliferation GO:0008284 249 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
regulation of membrane potential GO:0042391 110 0.019
positive regulation of molecular function GO:0044093 230 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
secretion GO:0046903 307 0.019
intracellular transport GO:0046907 185 0.019
neuron development GO:0048666 286 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
response to decreased oxygen levels GO:0036293 237 0.019
localization of cell GO:0051674 202 0.019
regulation of response to stress GO:0080134 126 0.019
metal ion transport GO:0030001 289 0.018
cell migration GO:0016477 197 0.018
response to radiation GO:0009314 137 0.018
regulation of system process GO:0044057 208 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
cellular response to lipid GO:0071396 201 0.018
response to growth factor GO:0070848 189 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
macromolecular complex assembly GO:0065003 273 0.018
circulatory system process GO:0003013 183 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
muscle system process GO:0003012 115 0.018
response to ketone GO:1901654 182 0.018
cellular response to stress GO:0033554 269 0.018
response to estrogen GO:0043627 232 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of ion transport GO:0043269 245 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
neuron projection development GO:0031175 273 0.017
response to mechanical stimulus GO:0009612 134 0.017
gliogenesis GO:0042063 93 0.017
positive regulation of cell development GO:0010720 176 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
gland development GO:0048732 155 0.017
inorganic cation transmembrane transport GO:0098662 202 0.017
inflammatory response GO:0006954 150 0.017
heart morphogenesis GO:0003007 3 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
growth GO:0040007 165 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
leukocyte activation GO:0045321 76 0.017
response to oxygen levels GO:0070482 265 0.017
organic substance catabolic process GO:1901575 316 0.017
response to lipopolysaccharide GO:0032496 191 0.017
positive regulation of protein metabolic process GO:0051247 178 0.016
brain development GO:0007420 247 0.016
behavior GO:0007610 205 0.016
cell activation GO:0001775 97 0.016
positive regulation of protein modification process GO:0031401 142 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
aromatic compound catabolic process GO:0019439 168 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
proteolysis GO:0006508 175 0.016
synaptic transmission GO:0007268 235 0.016
response to corticosteroid GO:0031960 235 0.016
cellular response to external stimulus GO:0071496 118 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
response to ethanol GO:0045471 162 0.016
calcium ion transport GO:0006816 131 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
regulation of cellular localization GO:0060341 263 0.016
regeneration GO:0031099 163 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
protein transport GO:0015031 132 0.016
secretion by cell GO:0032940 248 0.016
regulation of catalytic activity GO:0050790 304 0.016
regulation of secretion by cell GO:1903530 208 0.016
regulation of protein transport GO:0051223 68 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
divalent metal ion transport GO:0070838 132 0.016
cellular response to growth factor stimulus GO:0071363 162 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
circulatory system development GO:0072359 134 0.015
establishment of protein localization GO:0045184 141 0.015
cellular protein localization GO:0034613 122 0.015
regulation of hormone levels GO:0010817 187 0.015
negative regulation of signaling GO:0023057 157 0.015
regulation of neurogenesis GO:0050767 247 0.015
response to estradiol GO:0032355 164 0.015
anterior posterior pattern specification GO:0009952 1 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of immune system process GO:0002684 90 0.015
cellular macromolecule localization GO:0070727 122 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
divalent inorganic cation transport GO:0072511 134 0.015
muscle contraction GO:0006936 88 0.015
nucleoside metabolic process GO:0009116 179 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
regulation of locomotion GO:0040012 148 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
female pregnancy GO:0007565 122 0.014
regulation of anatomical structure size GO:0090066 135 0.014
response to vitamin GO:0033273 131 0.014
negative regulation of gene expression GO:0010629 199 0.014
regulation of cellular component movement GO:0051270 150 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
sexual reproduction GO:0019953 148 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
regulation of cell migration GO:0030334 128 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to cytokine GO:0034097 215 0.014
axis specification GO:0009798 4 0.014
regulation of metal ion transport GO:0010959 118 0.014
regulation of transferase activity GO:0051338 123 0.014
negative regulation of molecular function GO:0044092 133 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
sequestering of calcium ion GO:0051208 8 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
glial cell differentiation GO:0010001 65 0.014
response to carbohydrate GO:0009743 183 0.014
carbohydrate metabolic process GO:0005975 130 0.013
cardiovascular system development GO:0072358 134 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
response to toxic substance GO:0009636 133 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
multi multicellular organism process GO:0044706 138 0.013
sequestering of metal ion GO:0051238 9 0.013
head development GO:0060322 247 0.013
protein oligomerization GO:0051259 191 0.013
developmental process involved in reproduction GO:0003006 159 0.013
oxidation reduction process GO:0055114 304 0.013
cytoplasmic transport GO:0016482 115 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
second messenger mediated signaling GO:0019932 51 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
positive regulation of secretion GO:0051047 140 0.013
response to reactive oxygen species GO:0000302 120 0.013
regulation of cellular component organization GO:0051128 368 0.013
Rat
response to monosaccharide GO:0034284 159 0.013
purine containing compound catabolic process GO:0072523 138 0.012
heterocycle catabolic process GO:0046700 167 0.012
eye morphogenesis GO:0048592 4 0.012
salivary gland development GO:0007431 3 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of transport GO:0051051 136 0.012
response to glucocorticoid GO:0051384 223 0.012
neuron projection morphogenesis GO:0048812 122 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
organelle organization GO:0006996 266 0.012
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.012
multicellular organismal signaling GO:0035637 44 0.012
epithelium development GO:0060429 96 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
neuron death GO:0070997 127 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
gastrulation GO:0007369 2 0.012
vascular process in circulatory system GO:0003018 96 0.012
regulation of cell motility GO:2000145 131 0.012
anion transport GO:0006820 178 0.012
lipid metabolic process GO:0006629 283 0.012
negative regulation of cell communication GO:0010648 158 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cell growth GO:0016049 104 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of neuron death GO:1901214 115 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regulation of hydrolase activity GO:0051336 143 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cytokine biosynthetic process GO:0042089 3 0.012
cell type specific apoptotic process GO:0097285 134 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
action potential GO:0001508 54 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
developmental growth GO:0048589 100 0.012
response to alkaloid GO:0043279 132 0.012
cell motility GO:0048870 202 0.012
regulation of defense response GO:0031347 68 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
leukocyte cell cell adhesion GO:0007159 4 0.012
wound healing GO:0042060 122 0.011
response to glucose GO:0009749 136 0.011
male gamete generation GO:0048232 99 0.011
regulation of catabolic process GO:0009894 113 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
antigen receptor mediated signaling pathway GO:0050851 1 0.011
regulation of protein kinase activity GO:0045859 105 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
t cell tolerance induction GO:0002517 3 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
regulation of cell projection organization GO:0031344 175 0.011
Rat
transmission of nerve impulse GO:0019226 42 0.011
organic acid transport GO:0015849 116 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
neuromuscular process GO:0050905 2 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
gamete generation GO:0007276 124 0.011
signal release GO:0023061 145 0.011
peptidyl amino acid modification GO:0018193 126 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of homeostatic process GO:0032844 101 0.011
cell part morphogenesis GO:0032990 123 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
sensory perception GO:0007600 101 0.011
embryonic pattern specification GO:0009880 1 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
nucleotide catabolic process GO:0009166 139 0.011
response to hydrogen peroxide GO:0042542 89 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
positive regulation of cell migration GO:0030335 96 0.010
dna metabolic process GO:0006259 96 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of mapk cascade GO:0043408 116 0.010
rhythmic process GO:0048511 156 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
regulation of tube size GO:0035150 89 0.010
regulation of growth GO:0040008 105 0.010
potassium ion transport GO:0006813 97 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
reproductive system development GO:0061458 128 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
response to hexose GO:0009746 144 0.010
negative regulation of developmental process GO:0051093 125 0.010
response to insulin GO:0032868 133 0.010
cellular component morphogenesis GO:0032989 155 0.010
regulation of neuron projection development GO:0010975 161 0.010
rna localization GO:0006403 4 0.010
neuron apoptotic process GO:0051402 88 0.010
response to purine containing compound GO:0014074 126 0.010

Was disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
Human
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.018
sensory system disease DOID:0050155 0 0.014
connective tissue disease DOID:65 0 0.011
disease of metabolism DOID:0014667 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
central nervous system disease DOID:331 0 0.010