Rattus norvegicus

0 known processes

Defa-rs1

defensin alpha-related sequence 1

Defa-rs1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.251
organic acid metabolic process GO:0006082 292 0.175
cell cell signaling GO:0007267 335 0.130
oxoacid metabolic process GO:0043436 290 0.126
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.115
positive regulation of biosynthetic process GO:0009891 319 0.111
regulation of transcription dna templated GO:0006355 374 0.104
cellular response to oxygen containing compound GO:1901701 386 0.098
purine nucleoside metabolic process GO:0042278 169 0.095
purine containing compound metabolic process GO:0072521 253 0.093
organic acid biosynthetic process GO:0016053 83 0.092
response to extracellular stimulus GO:0009991 380 0.087
nucleic acid templated transcription GO:0097659 379 0.081
regulation of nucleic acid templated transcription GO:1903506 380 0.081
regulation of apoptotic process GO:0042981 335 0.081
positive regulation of nucleotide metabolic process GO:0045981 91 0.076
regulation of secretion GO:0051046 224 0.074
response to purine containing compound GO:0014074 126 0.073
regulation of cellular ketone metabolic process GO:0010565 27 0.072
anion transmembrane transport GO:0098656 77 0.070
purine nucleotide metabolic process GO:0006163 229 0.067
neuron differentiation GO:0030182 368 0.067
nucleobase containing small molecule metabolic process GO:0055086 316 0.065
response to carbohydrate GO:0009743 183 0.062
negative regulation of multicellular organismal process GO:0051241 203 0.061
cellular ketone metabolic process GO:0042180 51 0.061
ribonucleoside metabolic process GO:0009119 174 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.058
response to external biotic stimulus GO:0043207 221 0.057
Human
programmed cell death GO:0012501 392 0.057
response to nutrient levels GO:0031667 370 0.055
positive regulation of nucleic acid templated transcription GO:1903508 197 0.055
organonitrogen compound biosynthetic process GO:1901566 167 0.055
regulation of cellular localization GO:0060341 263 0.053
transcription from rna polymerase ii promoter GO:0006366 252 0.051
negative regulation of programmed cell death GO:0043069 183 0.049
cellular amino acid metabolic process GO:0006520 107 0.049
response to oxygen levels GO:0070482 265 0.049
purine ribonucleoside metabolic process GO:0046128 168 0.048
response to camp GO:0051591 91 0.048
cellular response to organic cyclic compound GO:0071407 202 0.047
heart development GO:0007507 72 0.046
positive regulation of cellular biosynthetic process GO:0031328 295 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.044
neuron development GO:0048666 286 0.043
carboxylic acid biosynthetic process GO:0046394 83 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.041
response to cytokine GO:0034097 215 0.041
cellular response to cytokine stimulus GO:0071345 127 0.040
regulation of synaptic transmission GO:0050804 141 0.040
protein heterooligomerization GO:0051291 89 0.040
positive regulation of rna metabolic process GO:0051254 203 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
amine metabolic process GO:0009308 38 0.039
ribonucleotide metabolic process GO:0009259 231 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.039
ribose phosphate metabolic process GO:0019693 235 0.037
hormone metabolic process GO:0042445 69 0.037
action potential GO:0001508 54 0.037
head development GO:0060322 247 0.035
response to inorganic substance GO:0010035 377 0.035
regulation of secretion by cell GO:1903530 208 0.035
glycosyl compound metabolic process GO:1901657 182 0.035
regulation of ion transport GO:0043269 245 0.034
nucleotide metabolic process GO:0009117 279 0.034
transcription dna templated GO:0006351 377 0.034
protein complex biogenesis GO:0070271 263 0.034
response to alkaloid GO:0043279 132 0.033
purine ribonucleoside catabolic process GO:0046130 124 0.033
regulation of cell differentiation GO:0045595 320 0.032
neuronal action potential GO:0019228 35 0.032
protein complex assembly GO:0006461 263 0.032
regulation of rna metabolic process GO:0051252 391 0.032
response to organophosphorus GO:0046683 102 0.032
single organism catabolic process GO:0044712 283 0.032
homeostatic process GO:0042592 331 0.032
rna biosynthetic process GO:0032774 380 0.031
monocarboxylic acid biosynthetic process GO:0072330 48 0.031
cellular amine metabolic process GO:0044106 38 0.030
carbohydrate homeostasis GO:0033500 75 0.030
secretion GO:0046903 307 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
response to monosaccharide GO:0034284 159 0.028
neurological system process GO:0050877 219 0.028
single organism reproductive process GO:0044702 297 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.028
regulation of molecular function GO:0065009 398 0.028
organonitrogen compound catabolic process GO:1901565 179 0.028
reproductive process GO:0022414 372 0.027
reproductive structure development GO:0048608 128 0.027
organophosphate metabolic process GO:0019637 370 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
positive regulation of secretion GO:0051047 140 0.027
rhythmic process GO:0048511 156 0.027
regulation of programmed cell death GO:0043067 341 0.027
ribonucleoside triphosphate metabolic process GO:0009199 141 0.026
response to ethanol GO:0045471 162 0.026
negative regulation of apoptotic process GO:0043066 181 0.026
rna metabolic process GO:0016070 406 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
transmission of nerve impulse GO:0019226 42 0.025
regulation of purine nucleotide metabolic process GO:1900542 115 0.025
response to hexose GO:0009746 144 0.025
protein complex subunit organization GO:0071822 302 0.025
locomotion GO:0040011 237 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
regulation of calcium ion transport GO:0051924 77 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
response to decreased oxygen levels GO:0036293 237 0.024
blood circulation GO:0008015 183 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
alpha amino acid metabolic process GO:1901605 71 0.023
catabolic process GO:0009056 351 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.023
regulation of membrane potential GO:0042391 110 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
regulation of system process GO:0044057 208 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
synaptic transmission GO:0007268 235 0.022
response to glucose GO:0009749 136 0.022
nucleoside metabolic process GO:0009116 179 0.022
regulation of transmembrane transport GO:0034762 122 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
response to acid chemical GO:0001101 222 0.022
brain development GO:0007420 247 0.022
multicellular organismal reproductive process GO:0048609 233 0.021
central nervous system development GO:0007417 311 0.021
response to other organism GO:0051707 220 0.021
Human
monocarboxylic acid metabolic process GO:0032787 152 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
divalent inorganic cation transport GO:0072511 134 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
regulation of protein modification process GO:0031399 194 0.020
sexual reproduction GO:0019953 148 0.020
response to growth factor GO:0070848 189 0.020
macromolecular complex subunit organization GO:0043933 339 0.019
multicellular organism reproduction GO:0032504 233 0.019
negative regulation of metabolic process GO:0009892 331 0.019
positive regulation of molecular function GO:0044093 230 0.019
regulation of neurogenesis GO:0050767 247 0.019
cellular component biogenesis GO:0044085 368 0.019
proteolysis GO:0006508 175 0.018
circulatory system development GO:0072359 134 0.018
tissue development GO:0009888 252 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
cellular component movement GO:0006928 248 0.018
dna metabolic process GO:0006259 96 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of catalytic activity GO:0050790 304 0.018
positive regulation of gene expression GO:0010628 244 0.018
epithelium development GO:0060429 96 0.018
regulation of neuron differentiation GO:0045664 208 0.018
development of primary sexual characteristics GO:0045137 107 0.017
signal release GO:0023061 145 0.017
cardiovascular system development GO:0072358 134 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
anion transport GO:0006820 178 0.017
circadian rhythm GO:0007623 88 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
spermatogenesis GO:0007283 99 0.017
positive regulation of transcription dna templated GO:0045893 197 0.016
response to metal ion GO:0010038 253 0.016
axon development GO:0061564 96 0.016
response to nicotine GO:0035094 51 0.016
negative regulation of cell death GO:0060548 229 0.016
cellular response to stress GO:0033554 269 0.016
chemical homeostasis GO:0048878 292 0.016
regulation of nervous system development GO:0051960 264 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
response to bacterium GO:0009617 200 0.016
Human
nucleobase containing compound catabolic process GO:0034655 152 0.016
protein localization GO:0008104 191 0.016
negative regulation of transport GO:0051051 136 0.015
ion transmembrane transport GO:0034220 365 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
regulation of peptide secretion GO:0002791 82 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
macromolecular complex assembly GO:0065003 273 0.015
cellular chemical homeostasis GO:0055082 247 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cellular response to lipid GO:0071396 201 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
phosphatidylinositol dephosphorylation GO:0046856 4 0.014
glucose homeostasis GO:0042593 75 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
regulation of hormone levels GO:0010817 187 0.014
muscle contraction GO:0006936 88 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
positive regulation of transport GO:0051050 245 0.014
regulation of neuronal synaptic plasticity GO:0048168 31 0.014
thyroid gland development GO:0030878 1 0.014
phenol containing compound metabolic process GO:0018958 30 0.014
protein oligomerization GO:0051259 191 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
calcium ion transport GO:0006816 131 0.013
cellular catabolic process GO:0044248 295 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
response to peptide hormone GO:0043434 278 0.013
multicellular organismal signaling GO:0035637 44 0.013
telencephalon development GO:0021537 62 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
maintenance of location GO:0051235 17 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
endocrine system development GO:0035270 30 0.013
sensory organ development GO:0007423 74 0.013
metal ion transport GO:0030001 289 0.013
cellular component morphogenesis GO:0032989 155 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
cell type specific apoptotic process GO:0097285 134 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
ras protein signal transduction GO:0007265 29 0.013
gonad development GO:0008406 104 0.013
cellular response to gonadotropin stimulus GO:0071371 17 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
reproduction GO:0000003 245 0.013
male sex differentiation GO:0046661 64 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
multi organism reproductive process GO:0044703 262 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
intracellular signal transduction GO:0035556 314 0.012
regulation of protein metabolic process GO:0051246 289 0.012
regulation of hormone secretion GO:0046883 106 0.012
chromosome segregation GO:0007059 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cellular hormone metabolic process GO:0034754 49 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
fatty acid derivative metabolic process GO:1901568 38 0.012
leukocyte activation GO:0045321 76 0.012
apoptotic process GO:0006915 381 0.012
response to vitamin GO:0033273 131 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of neuron death GO:1901214 115 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regulation of insulin secretion GO:0050796 65 0.012
eye morphogenesis GO:0048592 4 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
single organism biosynthetic process GO:0044711 342 0.012
positive regulation of dna metabolic process GO:0051054 39 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
gamete generation GO:0007276 124 0.011
neuron fate commitment GO:0048663 4 0.011
cation transport GO:0006812 382 0.011
monocarboxylic acid transport GO:0015718 52 0.011
regulation of neuron projection development GO:0010975 161 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
cellular lipid metabolic process GO:0044255 208 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
nucleoside catabolic process GO:0009164 126 0.011
vesicle mediated transport GO:0016192 181 0.011
cellular response to metal ion GO:0071248 55 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
negative regulation of nervous system development GO:0051961 79 0.011
heart morphogenesis GO:0003007 3 0.011
response to fungicide GO:0060992 20 0.011
coenzyme metabolic process GO:0006732 86 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to peptide GO:1901652 292 0.011
response to insecticide GO:0017085 21 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
response to estradiol GO:0032355 164 0.011
response to gonadotropin GO:0034698 34 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
regulation of dendrite development GO:0050773 59 0.011
growth GO:0040007 165 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
cell growth GO:0016049 104 0.011
cell activation GO:0001775 97 0.011
regulation of dna metabolic process GO:0051052 60 0.011
response to histamine GO:0034776 3 0.010
response to insulin GO:0032868 133 0.010
male gamete generation GO:0048232 99 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
myelination GO:0042552 39 0.010
regulation of anion transport GO:0044070 43 0.010
hormone secretion GO:0046879 115 0.010
axonogenesis GO:0007409 71 0.010
response to oxidative stress GO:0006979 186 0.010
response to radiation GO:0009314 137 0.010
divalent metal ion transport GO:0070838 132 0.010
negative regulation of cell development GO:0010721 82 0.010
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.010
protein maturation GO:0051604 68 0.010
fatty acid derivative biosynthetic process GO:1901570 18 0.010

Defa-rs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.025
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025