Rattus norvegicus

0 known processes

Eps8l1

EPS8-like 1

Eps8l1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.114
positive regulation of cell proliferation GO:0008284 249 0.096
response to peptide hormone GO:0043434 278 0.081
positive regulation of biosynthetic process GO:0009891 319 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.075
response to acid chemical GO:0001101 222 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
Human
response to inorganic substance GO:0010035 377 0.070
aromatic compound catabolic process GO:0019439 168 0.065
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.062
cellular calcium ion homeostasis GO:0006874 160 0.060
regulation of cellular component organization GO:0051128 368 0.057
Human
multi multicellular organism process GO:0044706 138 0.055
transcription dna templated GO:0006351 377 0.054
regulation of rna metabolic process GO:0051252 391 0.054
nucleic acid templated transcription GO:0097659 379 0.052
regulation of apoptotic process GO:0042981 335 0.051
rna metabolic process GO:0016070 406 0.050
programmed cell death GO:0012501 392 0.049
regulation of rna biosynthetic process GO:2001141 381 0.048
anatomical structure morphogenesis GO:0009653 298 0.048
intracellular signal transduction GO:0035556 314 0.047
Human
regulation of transcription dna templated GO:0006355 374 0.046
regulation of protein metabolic process GO:0051246 289 0.046
response to metal ion GO:0010038 253 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.044
cell growth GO:0016049 104 0.043
multi organism reproductive process GO:0044703 262 0.043
tissue development GO:0009888 252 0.043
cardiovascular system development GO:0072358 134 0.043
chemical homeostasis GO:0048878 292 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.042
circulatory system process GO:0003013 183 0.041
response to estrogen GO:0043627 232 0.040
negative regulation of apoptotic process GO:0043066 181 0.039
immune system process GO:0002376 204 0.039
positive regulation of developmental process GO:0051094 283 0.038
negative regulation of gene expression GO:0010629 199 0.038
regulation of immune system process GO:0002682 123 0.038
gland development GO:0048732 155 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
positive regulation of gene expression GO:0010628 244 0.037
cell morphogenesis involved in differentiation GO:0000904 119 0.036
negative regulation of programmed cell death GO:0043069 183 0.036
organ morphogenesis GO:0009887 75 0.035
negative regulation of biosynthetic process GO:0009890 168 0.035
negative regulation of cell death GO:0060548 229 0.035
rna biosynthetic process GO:0032774 380 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
response to extracellular stimulus GO:0009991 380 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
regulation of cellular component movement GO:0051270 150 0.034
response to oxidative stress GO:0006979 186 0.033
positive regulation of catalytic activity GO:0043085 184 0.033
Human
regulation of intracellular signal transduction GO:1902531 218 0.033
Human
regulation of programmed cell death GO:0043067 341 0.033
cellular component movement GO:0006928 248 0.033
regulation of catalytic activity GO:0050790 304 0.033
Human
cation homeostasis GO:0055080 195 0.032
cellular amine metabolic process GO:0044106 38 0.032
ribonucleoside triphosphate catabolic process GO:0009203 122 0.032
Human
reproductive process GO:0022414 372 0.032
circulatory system development GO:0072359 134 0.032
biological adhesion GO:0022610 110 0.031
female pregnancy GO:0007565 122 0.030
regulation of molecular function GO:0065009 398 0.030
Human
regulation of signal transduction GO:0009966 318 0.030
Human
cellular ketone metabolic process GO:0042180 51 0.030
neuron differentiation GO:0030182 368 0.029
cellular component assembly GO:0022607 360 0.029
Human
single organism reproductive process GO:0044702 297 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
negative regulation of metabolic process GO:0009892 331 0.029
response to peptide GO:1901652 292 0.029
cellular response to stress GO:0033554 269 0.028
positive regulation of programmed cell death GO:0043068 157 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
negative regulation of cell proliferation GO:0008285 119 0.027
response to nutrient levels GO:0031667 370 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
protein phosphorylation GO:0006468 345 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
apoptotic process GO:0006915 381 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
neuron projection development GO:0031175 273 0.026
cellular component morphogenesis GO:0032989 155 0.026
response to mechanical stimulus GO:0009612 134 0.026
cellular cation homeostasis GO:0030003 180 0.025
oxoacid metabolic process GO:0043436 290 0.025
nucleoside metabolic process GO:0009116 179 0.025
Human
response to nutrient GO:0007584 248 0.025
single organism catabolic process GO:0044712 283 0.025
Human
proteolysis GO:0006508 175 0.025
sensory organ development GO:0007423 74 0.025
defense response GO:0006952 194 0.025
multicellular organism reproduction GO:0032504 233 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
Human
regulation of cell differentiation GO:0045595 320 0.025
single organism cell adhesion GO:0098602 46 0.024
regulation of cell development GO:0060284 263 0.024
positive regulation of cell death GO:0010942 184 0.024
growth GO:0040007 165 0.024
salivary gland development GO:0007431 3 0.024
regulation of nervous system development GO:0051960 264 0.024
cell morphogenesis GO:0000902 142 0.024
ion homeostasis GO:0050801 212 0.024
small gtpase mediated signal transduction GO:0007264 36 0.023
Human
reproduction GO:0000003 245 0.023
kidney development GO:0001822 67 0.023
purine nucleoside triphosphate metabolic process GO:0009144 141 0.023
Human
positive regulation of rna metabolic process GO:0051254 203 0.023
positive regulation of cell development GO:0010720 176 0.023
purine ribonucleotide catabolic process GO:0009154 136 0.023
Human
carbohydrate derivative metabolic process GO:1901135 346 0.023
Human
cellular metal ion homeostasis GO:0006875 172 0.023
organophosphate catabolic process GO:0046434 148 0.023
Human
ras protein signal transduction GO:0007265 29 0.022
Human
positive regulation of cell communication GO:0010647 271 0.022
cellular homeostasis GO:0019725 252 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
Human
smooth muscle cell proliferation GO:0048659 77 0.022
catabolic process GO:0009056 351 0.022
Human
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
Human
positive regulation of immune system process GO:0002684 90 0.022
blood circulation GO:0008015 183 0.021
amine metabolic process GO:0009308 38 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.021
Human
regulation of neuron differentiation GO:0045664 208 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
Human
organic substance catabolic process GO:1901575 316 0.021
Human
response to oxygen levels GO:0070482 265 0.021
cellular ion homeostasis GO:0006873 184 0.021
cellular component biogenesis GO:0044085 368 0.021
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
nucleotide metabolic process GO:0009117 279 0.021
Human
regulation of membrane potential GO:0042391 110 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.020
neuron development GO:0048666 286 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
Human
purine ribonucleoside catabolic process GO:0046130 124 0.020
Human
response to ketone GO:1901654 182 0.020
heterocycle catabolic process GO:0046700 167 0.020
Human
regulation of protein modification process GO:0031399 194 0.020
antigen receptor mediated signaling pathway GO:0050851 1 0.020
regulation of cell motility GO:2000145 131 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
Human
positive regulation of nervous system development GO:0051962 178 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
Human
immune response GO:0006955 104 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
protein complex assembly GO:0006461 263 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
Human
positive regulation of molecular function GO:0044093 230 0.020
Human
positive regulation of cell differentiation GO:0045597 217 0.020
organic acid metabolic process GO:0006082 292 0.020
regulation of phosphorylation GO:0042325 248 0.019
epithelial cell differentiation GO:0030855 71 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
Human
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
aging GO:0007568 241 0.019
response to wounding GO:0009611 254 0.019
purine containing compound catabolic process GO:0072523 138 0.019
Human
activation of immune response GO:0002253 26 0.019
epithelium development GO:0060429 96 0.019
multicellular organismal homeostasis GO:0048871 49 0.019
positive regulation of transport GO:0051050 245 0.019
organelle organization GO:0006996 266 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
Human
ribonucleoside metabolic process GO:0009119 174 0.019
Human
regeneration GO:0031099 163 0.019
positive regulation of signaling GO:0023056 270 0.019
regulation of protein phosphorylation GO:0001932 183 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
homeostatic process GO:0042592 331 0.018
heart morphogenesis GO:0003007 3 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
protein complex biogenesis GO:0070271 263 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
Human
purine containing compound metabolic process GO:0072521 253 0.018
Human
carboxylic acid metabolic process GO:0019752 289 0.018
nucleoside triphosphate metabolic process GO:0009141 144 0.018
Human
negative regulation of transport GO:0051051 136 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.017
Human
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
Human
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
fatty acid biosynthetic process GO:0006633 33 0.017
muscle cell proliferation GO:0033002 84 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
Human
urogenital system development GO:0001655 78 0.017
regulation of neurogenesis GO:0050767 247 0.017
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of cell growth GO:0001558 85 0.017
response to reactive oxygen species GO:0000302 120 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
organophosphate metabolic process GO:0019637 370 0.016
Human
ribose phosphate metabolic process GO:0019693 235 0.016
Human
organic cyclic compound catabolic process GO:1901361 175 0.016
Human
metanephric comma shaped body morphogenesis GO:0072278 2 0.016
nucleotide catabolic process GO:0009166 139 0.016
Human
action potential GO:0001508 54 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
macromolecular complex assembly GO:0065003 273 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
response to decreased oxygen levels GO:0036293 237 0.016
cell adhesion GO:0007155 110 0.016
localization of cell GO:0051674 202 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
purine nucleotide catabolic process GO:0006195 136 0.015
Human
protein complex subunit organization GO:0071822 302 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
Human
negative regulation of cell communication GO:0010648 158 0.015
regulation of body fluid levels GO:0050878 90 0.015
regulation of blood pressure GO:0008217 83 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
cell projection organization GO:0030030 302 0.015
Human
nucleoside triphosphate catabolic process GO:0009143 123 0.015
Human
negative regulation of molecular function GO:0044092 133 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
cell cycle GO:0007049 101 0.015
multicellular organismal signaling GO:0035637 44 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
Human
response to hydrogen peroxide GO:0042542 89 0.015
hematopoietic progenitor cell differentiation GO:0002244 2 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of system process GO:0044057 208 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
unsaturated fatty acid metabolic process GO:0033559 39 0.014
intracellular transport GO:0046907 185 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
Human
gonad development GO:0008406 104 0.014
wound healing GO:0042060 122 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
regulation of cell projection organization GO:0031344 175 0.014
Human
peptidyl tyrosine modification GO:0018212 72 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
Human
regulation of cell adhesion GO:0030155 52 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
response to ethanol GO:0045471 162 0.014
bmp signaling pathway GO:0030509 4 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of synaptic transmission GO:0050804 141 0.014
central nervous system development GO:0007417 311 0.014
regulation of nucleoside metabolic process GO:0009118 66 0.014
Human
cellular catabolic process GO:0044248 295 0.014
Human
positive regulation of protein modification process GO:0031401 142 0.014
gamete generation GO:0007276 124 0.014
lipid storage GO:0019915 1 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
transmembrane transport GO:0055085 412 0.014
regulation of neuron projection development GO:0010975 161 0.014
salivary gland morphogenesis GO:0007435 1 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.013
Human
ion transmembrane transport GO:0034220 365 0.013
vasculature development GO:0001944 70 0.013
organic acid biosynthetic process GO:0016053 83 0.013
regulation of cellular localization GO:0060341 263 0.013
fatty acid derivative metabolic process GO:1901568 38 0.013
sexual reproduction GO:0019953 148 0.013
blood vessel development GO:0001568 69 0.013
single organism organelle organization GO:1902589 180 0.013
regulation of neuron death GO:1901214 115 0.013
embryonic pattern specification GO:0009880 1 0.013
cell projection morphogenesis GO:0048858 123 0.013
inflammatory response GO:0006954 150 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cellular response to peptide GO:1901653 133 0.013
renal system development GO:0072001 67 0.013
regulation of nucleotide catabolic process GO:0030811 65 0.013
Human
rho protein signal transduction GO:0007266 11 0.013
Human
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
cellular chemical homeostasis GO:0055082 247 0.013
spermatogenesis GO:0007283 99 0.013
muscle system process GO:0003012 115 0.013
locomotion GO:0040011 237 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
neuron projection morphogenesis GO:0048812 122 0.013
cell migration GO:0016477 197 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
positive regulation of immune response GO:0050778 42 0.012
icosanoid metabolic process GO:0006690 38 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
regulation of cell migration GO:0030334 128 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
neuron apoptotic process GO:0051402 88 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
axis specification GO:0009798 4 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
gliogenesis GO:0042063 93 0.012
negative regulation of signaling GO:0023057 157 0.012
cellular response to lipid GO:0071396 201 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
neurological system process GO:0050877 219 0.012
cellular response to external stimulus GO:0071496 118 0.012
lipid metabolic process GO:0006629 283 0.012
regulation of muscle system process GO:0090257 79 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
negative regulation of innate immune response GO:0045824 4 0.011
response to toxic substance GO:0009636 133 0.011
cell motility GO:0048870 202 0.011
regulation of hormone levels GO:0010817 187 0.011
cardiac chamber development GO:0003205 1 0.011
protein oligomerization GO:0051259 191 0.011
response to vitamin GO:0033273 131 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
Human
regulation of mapk cascade GO:0043408 116 0.011
metanephric s shaped body morphogenesis GO:0072284 2 0.011
regulation of growth GO:0040008 105 0.011
axon development GO:0061564 96 0.011
establishment of tissue polarity GO:0007164 2 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
transmission of nerve impulse GO:0019226 42 0.011
positive regulation of locomotion GO:0040017 102 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cell type specific apoptotic process GO:0097285 134 0.011
dna metabolic process GO:0006259 96 0.011
single organism cellular localization GO:1902580 102 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
Human
positive regulation of cell migration GO:0030335 96 0.011
male gamete generation GO:0048232 99 0.011
regulation of transcription regulatory region dna binding GO:2000677 4 0.011
macromolecule localization GO:0033036 252 0.011
nucleoside catabolic process GO:0009164 126 0.011
Human
calcium ion homeostasis GO:0055074 162 0.011
axonogenesis GO:0007409 71 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
retinal ganglion cell axon guidance GO:0031290 1 0.011
response to insulin GO:0032868 133 0.011
fertilization GO:0009566 3 0.011
regulation of catabolic process GO:0009894 113 0.011
Human
glomerular mesangial cell proliferation GO:0072110 4 0.011
head development GO:0060322 247 0.011
response to activity GO:0014823 73 0.011
hepaticobiliary system development GO:0061008 90 0.011
cellular response to oxidative stress GO:0034599 76 0.011
developmental process involved in reproduction GO:0003006 159 0.011
striated muscle tissue development GO:0014706 58 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
Human
regulation of response to stress GO:0080134 126 0.010
regulation of immune response GO:0050776 55 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
single organism biosynthetic process GO:0044711 342 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
Human
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
Human
small molecule biosynthetic process GO:0044283 124 0.010
cytoplasmic transport GO:0016482 115 0.010
protein processing GO:0016485 68 0.010
developmental growth GO:0048589 100 0.010
cytokine production GO:0001816 61 0.010
chromosome segregation GO:0007059 2 0.010
heart process GO:0003015 57 0.010
cellular protein localization GO:0034613 122 0.010
response to retinoic acid GO:0032526 63 0.010
positive regulation of signal transduction GO:0009967 175 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
muscle structure development GO:0061061 87 0.010
immune response regulating signaling pathway GO:0002764 19 0.010
negative regulation of neurogenesis GO:0050768 78 0.010

Eps8l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.012
connective tissue disease DOID:65 0 0.011
nervous system disease DOID:863 0 0.011