Rattus norvegicus

40 known processes

Socs1

suppressor of cytokine signaling 1

(Aliases: Socs-1,Cish1)

Socs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.182
transcription dna templated GO:0006351 377 0.168
rna biosynthetic process GO:0032774 380 0.117
regulation of nucleic acid templated transcription GO:1903506 380 0.108
regulation of rna biosynthetic process GO:2001141 381 0.099
homeostatic process GO:0042592 331 0.088
regulation of transcription dna templated GO:0006355 374 0.083
inorganic cation transmembrane transport GO:0098662 202 0.079
transmembrane transport GO:0055085 412 0.075
ion transmembrane transport GO:0034220 365 0.073
regulation of rna metabolic process GO:0051252 391 0.071
regulation of secretion GO:0051046 224 0.064
Mouse
response to corticosteroid GO:0031960 235 0.063
Rat
amino acid transport GO:0006865 70 0.061
cellular response to nitrogen compound GO:1901699 210 0.060
Mouse
protein complex subunit organization GO:0071822 302 0.060
positive regulation of gene expression GO:0010628 244 0.059
transcription from rna polymerase ii promoter GO:0006366 252 0.057
anion transport GO:0006820 178 0.055
secretion GO:0046903 307 0.055
Mouse
rna metabolic process GO:0016070 406 0.054
positive regulation of transcription dna templated GO:0045893 197 0.052
response to nutrient levels GO:0031667 370 0.048
Rat
regulation of secretion by cell GO:1903530 208 0.046
Mouse
protein complex assembly GO:0006461 263 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.045
positive regulation of transport GO:0051050 245 0.044
macromolecule localization GO:0033036 252 0.044
Mouse
nitrogen compound transport GO:0071705 229 0.044
positive regulation of cell differentiation GO:0045597 217 0.043
macromolecular complex subunit organization GO:0043933 339 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
regeneration GO:0031099 163 0.041
negative regulation of transport GO:0051051 136 0.040
response to glucocorticoid GO:0051384 223 0.039
Rat
cell cell signaling GO:0007267 335 0.039
cation transmembrane transport GO:0098655 263 0.038
carboxylic acid transport GO:0046942 115 0.038
regulation of molecular function GO:0065009 398 0.037
Mouse
inorganic ion transmembrane transport GO:0098660 229 0.036
secretion by cell GO:0032940 248 0.035
Mouse
cellular component biogenesis GO:0044085 368 0.035
programmed cell death GO:0012501 392 0.034
signal release GO:0023061 145 0.033
cellular component assembly GO:0022607 360 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
chemical homeostasis GO:0048878 292 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
Mouse
organic acid transport GO:0015849 116 0.032
organic anion transport GO:0015711 132 0.032
positive regulation of secretion GO:0051047 140 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
regulation of apoptotic process GO:0042981 335 0.031
regulation of cellular localization GO:0060341 263 0.031
Mouse
response to ketone GO:1901654 182 0.030
monovalent inorganic cation transport GO:0015672 172 0.030
response to wounding GO:0009611 254 0.029
response to growth factor GO:0070848 189 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
response to mechanical stimulus GO:0009612 134 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
inflammatory response GO:0006954 150 0.027
aging GO:0007568 241 0.027
Rat
cellular chemical homeostasis GO:0055082 247 0.026
cation transport GO:0006812 382 0.026
lipid transport GO:0006869 61 0.026
regulation of metal ion transport GO:0010959 118 0.026
macromolecular complex assembly GO:0065003 273 0.026
negative regulation of biosynthetic process GO:0009890 168 0.025
negative regulation of signaling GO:0023057 157 0.025
Zebrafish Mouse
metal ion transport GO:0030001 289 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
regulation of cell projection organization GO:0031344 175 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
cell type specific apoptotic process GO:0097285 134 0.024
regulation of hormone levels GO:0010817 187 0.024
response to cytokine GO:0034097 215 0.024
response to biotic stimulus GO:0009607 226 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
protein oligomerization GO:0051259 191 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
response to peptide GO:1901652 292 0.023
negative regulation of metabolic process GO:0009892 331 0.023
Mouse
single organism biosynthetic process GO:0044711 342 0.022
lipid metabolic process GO:0006629 283 0.022
positive regulation of molecular function GO:0044093 230 0.022
Mouse
positive regulation of cell death GO:0010942 184 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
negative regulation of cell communication GO:0010648 158 0.021
Zebrafish Mouse
cellular response to cytokine stimulus GO:0071345 127 0.021
Zebrafish Mouse Rat
positive regulation of secretion by cell GO:1903532 128 0.021
response to hypoxia GO:0001666 231 0.021
Rat
regulation of cellular component organization GO:0051128 368 0.021
organophosphate metabolic process GO:0019637 370 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
reproductive process GO:0022414 372 0.021
protein complex biogenesis GO:0070271 263 0.020
cellular response to external stimulus GO:0071496 118 0.020
positive regulation of developmental process GO:0051094 283 0.020
vasculature development GO:0001944 70 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.019
Mouse
regulation of neuron apoptotic process GO:0043523 83 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
circulatory system process GO:0003013 183 0.018
acid secretion GO:0046717 48 0.018
regulation of transmembrane transport GO:0034762 122 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to oxygen levels GO:0070482 265 0.017
Rat
regulation of protein metabolic process GO:0051246 289 0.017
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
growth GO:0040007 165 0.017
peptide secretion GO:0002790 86 0.017
learning or memory GO:0007611 90 0.017
nucleotide metabolic process GO:0009117 279 0.016
response to decreased oxygen levels GO:0036293 237 0.016
Rat
response to extracellular stimulus GO:0009991 380 0.016
Rat
amine metabolic process GO:0009308 38 0.016
regulation of membrane potential GO:0042391 110 0.016
response to bacterium GO:0009617 200 0.016
negative regulation of gene expression GO:0010629 199 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
response to external biotic stimulus GO:0043207 221 0.016
protein localization GO:0008104 191 0.016
Mouse
response to toxic substance GO:0009636 133 0.016
positive regulation of apoptotic process GO:0043065 154 0.015
oxoacid metabolic process GO:0043436 290 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
Zebrafish Mouse
positive regulation of signaling GO:0023056 270 0.015
Mouse
response to insulin GO:0032868 133 0.015
Mouse Rat
response to hexose GO:0009746 144 0.015
defense response GO:0006952 194 0.015
Zebrafish
neuron apoptotic process GO:0051402 88 0.015
response to carbohydrate GO:0009743 183 0.015
circulatory system development GO:0072359 134 0.015
cellular response to stress GO:0033554 269 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
cellular cation homeostasis GO:0030003 180 0.015
glial cell differentiation GO:0010001 65 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
multicellular organism growth GO:0035264 1 0.015
hormone metabolic process GO:0042445 69 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
cellular response to drug GO:0035690 30 0.014
regulation of neuron differentiation GO:0045664 208 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
regulation of cell differentiation GO:0045595 320 0.014
positive regulation of hormone secretion GO:0046887 65 0.014
regulation of ion transport GO:0043269 245 0.014
central nervous system development GO:0007417 311 0.014
blood circulation GO:0008015 183 0.014
muscle system process GO:0003012 115 0.014
dicarboxylic acid transport GO:0006835 34 0.014
regulation of neurogenesis GO:0050767 247 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
aromatic compound catabolic process GO:0019439 168 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
organic substance catabolic process GO:1901575 316 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of growth GO:0045927 55 0.014
negative regulation of cell death GO:0060548 229 0.014
dna metabolic process GO:0006259 96 0.013
response to peptide hormone GO:0043434 278 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
response to glucose GO:0009749 136 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
response to axon injury GO:0048678 59 0.013
divalent inorganic cation transport GO:0072511 134 0.013
positive regulation of ion transport GO:0043270 94 0.013
regulation of blood pressure GO:0008217 83 0.013
regulation of leukocyte activation GO:0002694 45 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
regulation of hormone secretion GO:0046883 106 0.013
appendage morphogenesis GO:0035107 4 0.012
lipid localization GO:0010876 62 0.012
response to lipopolysaccharide GO:0032496 191 0.012
regulation of anion transport GO:0044070 43 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
response to alkaloid GO:0043279 132 0.012
cell projection organization GO:0030030 302 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of cell proliferation GO:0042127 359 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
cellular catabolic process GO:0044248 295 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
Mouse
cellular amine metabolic process GO:0044106 38 0.012
ras protein signal transduction GO:0007265 29 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
sexual reproduction GO:0019953 148 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.012
brain development GO:0007420 247 0.012
development of primary sexual characteristics GO:0045137 107 0.012
transmission of nerve impulse GO:0019226 42 0.012
neuron death GO:0070997 127 0.011
motor neuron axon guidance GO:0008045 1 0.011
proteolysis GO:0006508 175 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
multi organism reproductive process GO:0044703 262 0.011
single organism behavior GO:0044708 130 0.011
immune system process GO:0002376 204 0.011
Zebrafish
organic hydroxy compound metabolic process GO:1901615 115 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
monosaccharide metabolic process GO:0005996 61 0.011
regulation of synaptic transmission GO:0050804 141 0.011
establishment of protein localization GO:0045184 141 0.011
Mouse
single organism organelle organization GO:1902589 180 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
Zebrafish Mouse
positive regulation of cellular component organization GO:0051130 200 0.011
negative regulation of ion transport GO:0043271 51 0.011
action potential GO:0001508 54 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
cell activation GO:0001775 97 0.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.011
sensory perception of pain GO:0019233 73 0.011
head development GO:0060322 247 0.011
regulation of signal transduction GO:0009966 318 0.011
Zebrafish Mouse
regulation of establishment of protein localization GO:0070201 69 0.011
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
regulation of peptide secretion GO:0002791 82 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
synaptic transmission GO:0007268 235 0.011
hemopoiesis GO:0030097 34 0.011
Zebrafish
response to radiation GO:0009314 137 0.011
Rat
regulation of interleukin 6 production GO:0032675 12 0.010
potassium ion transport GO:0006813 97 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
Mouse
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
regulation of programmed cell death GO:0043067 341 0.010
heterocycle catabolic process GO:0046700 167 0.010
membrane organization GO:0061024 94 0.010
immune system development GO:0002520 41 0.010
Zebrafish
regulation of growth GO:0040008 105 0.010
response to estrogen GO:0043627 232 0.010
organ formation GO:0048645 3 0.010
cell growth GO:0016049 104 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
hormone transport GO:0009914 121 0.010
regulation of peptide transport GO:0090087 87 0.010

Socs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
connective tissue disease DOID:65 0 0.011