Rattus norvegicus

0 known processes

Lrrc8b

leucine rich repeat containing 8 family, member B

(Aliases: RGD1563429)

Lrrc8b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.082
positive regulation of multicellular organismal process GO:0051240 387 0.082
rna biosynthetic process GO:0032774 380 0.081
macromolecular complex subunit organization GO:0043933 339 0.073
neuron differentiation GO:0030182 368 0.071
neuron development GO:0048666 286 0.066
single organism biosynthetic process GO:0044711 342 0.066
anatomical structure morphogenesis GO:0009653 298 0.066
positive regulation of biosynthetic process GO:0009891 319 0.064
regulation of programmed cell death GO:0043067 341 0.060
transcription dna templated GO:0006351 377 0.059
regulation of multicellular organismal development GO:2000026 376 0.057
regulation of rna biosynthetic process GO:2001141 381 0.057
catabolic process GO:0009056 351 0.056
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
positive regulation of developmental process GO:0051094 283 0.051
programmed cell death GO:0012501 392 0.051
cellular ketone metabolic process GO:0042180 51 0.050
cellular component assembly GO:0022607 360 0.049
regulation of signal transduction GO:0009966 318 0.048
oxoacid metabolic process GO:0043436 290 0.048
organic substance catabolic process GO:1901575 316 0.048
homeostatic process GO:0042592 331 0.047
nucleic acid templated transcription GO:0097659 379 0.047
negative regulation of metabolic process GO:0009892 331 0.046
neuron projection development GO:0031175 273 0.045
cellular response to endogenous stimulus GO:0071495 377 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
transmembrane transport GO:0055085 412 0.044
cell cell signaling GO:0007267 335 0.043
neuron projection morphogenesis GO:0048812 122 0.043
regulation of transcription dna templated GO:0006355 374 0.042
lipid metabolic process GO:0006629 283 0.042
protein complex biogenesis GO:0070271 263 0.041
chemical homeostasis GO:0048878 292 0.041
response to oxygen levels GO:0070482 265 0.041
tissue development GO:0009888 252 0.040
response to decreased oxygen levels GO:0036293 237 0.040
cellular response to oxygen containing compound GO:1901701 386 0.040
negative regulation of biosynthetic process GO:0009890 168 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
apoptotic process GO:0006915 381 0.039
cellular component movement GO:0006928 248 0.039
negative regulation of signaling GO:0023057 157 0.038
rhythmic process GO:0048511 156 0.038
protein complex subunit organization GO:0071822 302 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
regulation of cell proliferation GO:0042127 359 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.036
cell morphogenesis involved in differentiation GO:0000904 119 0.036
response to inorganic substance GO:0010035 377 0.036
macromolecular complex assembly GO:0065003 273 0.035
cell projection organization GO:0030030 302 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
positive regulation of cell proliferation GO:0008284 249 0.035
protein complex assembly GO:0006461 263 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.034
response to hypoxia GO:0001666 231 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
organic acid metabolic process GO:0006082 292 0.034
protein phosphorylation GO:0006468 345 0.034
response to extracellular stimulus GO:0009991 380 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
locomotion GO:0040011 237 0.032
behavior GO:0007610 205 0.032
neurological system process GO:0050877 219 0.032
regulation of apoptotic process GO:0042981 335 0.031
single organism catabolic process GO:0044712 283 0.031
reproductive process GO:0022414 372 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
macromolecule localization GO:0033036 252 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
cellular catabolic process GO:0044248 295 0.029
aging GO:0007568 241 0.028
regulation of molecular function GO:0065009 398 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
ion transmembrane transport GO:0034220 365 0.028
metal ion transport GO:0030001 289 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
cellular component biogenesis GO:0044085 368 0.027
cation transport GO:0006812 382 0.027
single organism behavior GO:0044708 130 0.027
response to nutrient levels GO:0031667 370 0.026
organophosphate metabolic process GO:0019637 370 0.026
organelle organization GO:0006996 266 0.026
cellular amine metabolic process GO:0044106 38 0.026
negative regulation of cell communication GO:0010648 158 0.026
cellular response to alcohol GO:0097306 87 0.025
lipid biosynthetic process GO:0008610 128 0.025
response to growth factor GO:0070848 189 0.025
central nervous system development GO:0007417 311 0.025
response to estrogen GO:0043627 232 0.025
biological adhesion GO:0022610 110 0.024
rna metabolic process GO:0016070 406 0.024
axon development GO:0061564 96 0.024
intracellular signal transduction GO:0035556 314 0.024
regulation of phosphate metabolic process GO:0019220 349 0.023
cell migration GO:0016477 197 0.023
synaptic transmission GO:0007268 235 0.023
regulation of cellular component organization GO:0051128 368 0.023
reproduction GO:0000003 245 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
positive regulation of gene expression GO:0010628 244 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
response to carbohydrate GO:0009743 183 0.023
growth GO:0040007 165 0.022
regulation of phosphorylation GO:0042325 248 0.022
eye morphogenesis GO:0048592 4 0.022
regulation of cell differentiation GO:0045595 320 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
response to bacterium GO:0009617 200 0.022
response to nutrient GO:0007584 248 0.022
axis specification GO:0009798 4 0.022
dendrite morphogenesis GO:0048813 43 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
anterior posterior pattern specification GO:0009952 1 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
single organism intracellular transport GO:1902582 166 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
localization of cell GO:0051674 202 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
positive regulation of molecular function GO:0044093 230 0.021
nucleoside phosphate biosynthetic process GO:1901293 102 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
regulation of catabolic process GO:0009894 113 0.021
regulation of homeostatic process GO:0032844 101 0.021
ion homeostasis GO:0050801 212 0.021
response to other organism GO:0051707 220 0.021
negative regulation of response to stimulus GO:0048585 155 0.020
epithelium development GO:0060429 96 0.020
head development GO:0060322 247 0.020
response to peptide hormone GO:0043434 278 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
response to glucose GO:0009749 136 0.020
generation of precursor metabolites and energy GO:0006091 62 0.020
cell adhesion GO:0007155 110 0.020
multicellular organism growth GO:0035264 1 0.020
regulation of ion transport GO:0043269 245 0.020
single organism reproductive process GO:0044702 297 0.020
intracellular transport GO:0046907 185 0.020
response to cytokine GO:0034097 215 0.020
protein oligomerization GO:0051259 191 0.020
positive regulation of phosphorylation GO:0042327 177 0.019
regulation of protein modification process GO:0031399 194 0.019
dendrite development GO:0016358 72 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
single organism organelle organization GO:1902589 180 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
brain development GO:0007420 247 0.019
nucleotide metabolic process GO:0009117 279 0.019
negative regulation of cell death GO:0060548 229 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
cell projection morphogenesis GO:0048858 123 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
gastrulation GO:0007369 2 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
tube development GO:0035295 89 0.018
carbohydrate metabolic process GO:0005975 130 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
cell growth GO:0016049 104 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
response to tumor necrosis factor GO:0034612 56 0.018
response to peptide GO:1901652 292 0.018
vesicle mediated transport GO:0016192 181 0.018
cellular chemical homeostasis GO:0055082 247 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of cell development GO:0060284 263 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
positive regulation of cell development GO:0010720 176 0.018
response to lipopolysaccharide GO:0032496 191 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
positive regulation of signaling GO:0023056 270 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
regulation of nervous system development GO:0051960 264 0.017
cellular homeostasis GO:0019725 252 0.017
reproductive system development GO:0061458 128 0.017
regulation of neuron death GO:1901214 115 0.017
response to external biotic stimulus GO:0043207 221 0.017
protein localization GO:0008104 191 0.017
circulatory system development GO:0072359 134 0.017
response to monosaccharide GO:0034284 159 0.017
developmental process involved in reproduction GO:0003006 159 0.017
response to corticosteroid GO:0031960 235 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
regulation of growth GO:0040008 105 0.017
regulation of anatomical structure size GO:0090066 135 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
response to glucocorticoid GO:0051384 223 0.016
response to acid chemical GO:0001101 222 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
cellular component morphogenesis GO:0032989 155 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
purine containing compound metabolic process GO:0072521 253 0.016
glycolytic process GO:0006096 17 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
response to mechanical stimulus GO:0009612 134 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
embryonic pattern specification GO:0009880 1 0.016
circadian rhythm GO:0007623 88 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of cell migration GO:0030334 128 0.016
cell motility GO:0048870 202 0.016
reproductive structure development GO:0048608 128 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of locomotion GO:0040012 148 0.016
oxidation reduction process GO:0055114 304 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
response to oxidative stress GO:0006979 186 0.016
regulation of protein metabolic process GO:0051246 289 0.016
action potential GO:0001508 54 0.016
negative regulation of gene expression GO:0010629 199 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
motor neuron axon guidance GO:0008045 1 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.015
regulation of system process GO:0044057 208 0.015
regulation of neurogenesis GO:0050767 247 0.015
forebrain development GO:0030900 98 0.015
cellular response to peptide GO:1901653 133 0.015
amine metabolic process GO:0009308 38 0.015
response to biotic stimulus GO:0009607 226 0.015
development of primary sexual characteristics GO:0045137 107 0.015
response to hexose GO:0009746 144 0.015
response to radiation GO:0009314 137 0.015
transmission of nerve impulse GO:0019226 42 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
cardiovascular system development GO:0072358 134 0.015
regulation of cellular localization GO:0060341 263 0.015
response to ketone GO:1901654 182 0.015
regeneration GO:0031099 163 0.015
cellular protein localization GO:0034613 122 0.015
positive regulation of cell communication GO:0010647 271 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
response to insulin GO:0032868 133 0.014
lipid storage GO:0019915 1 0.014
sex differentiation GO:0007548 113 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
cellular lipid metabolic process GO:0044255 208 0.014
carbohydrate catabolic process GO:0016052 40 0.014
regulation of synaptic transmission GO:0050804 141 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
regulation of membrane potential GO:0042391 110 0.014
multicellular organismal signaling GO:0035637 44 0.014
cellular response to external stimulus GO:0071496 118 0.014
response to ethanol GO:0045471 162 0.014
organ morphogenesis GO:0009887 75 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of hormone levels GO:0010817 187 0.014
sexual reproduction GO:0019953 148 0.014
circulatory system process GO:0003013 183 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cellular response to lipid GO:0071396 201 0.014
cell part morphogenesis GO:0032990 123 0.014
multi organism reproductive process GO:0044703 262 0.014
single organism cellular localization GO:1902580 102 0.014
cognition GO:0050890 92 0.014
protein heterooligomerization GO:0051291 89 0.014
negative regulation of molecular function GO:0044092 133 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
positive regulation of signal transduction GO:0009967 175 0.014
nucleoside metabolic process GO:0009116 179 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
positive regulation of cell migration GO:0030335 96 0.014
monosaccharide metabolic process GO:0005996 61 0.013
regulation of catalytic activity GO:0050790 304 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
carbohydrate homeostasis GO:0033500 75 0.013
regulation of cell motility GO:2000145 131 0.013
urogenital system development GO:0001655 78 0.013
ras protein signal transduction GO:0007265 29 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
anion transport GO:0006820 178 0.013
cellular response to oxidative stress GO:0034599 76 0.013
cation transmembrane transport GO:0098655 263 0.013
aromatic compound catabolic process GO:0019439 168 0.013
response to metal ion GO:0010038 253 0.013
cellular response to stress GO:0033554 269 0.013
defense response GO:0006952 194 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
positive regulation of nervous system development GO:0051962 178 0.013
regulation of cell growth GO:0001558 85 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
heart morphogenesis GO:0003007 3 0.013
metal ion homeostasis GO:0055065 186 0.012
gonad development GO:0008406 104 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of neuron projection development GO:0010975 161 0.012
anion transmembrane transport GO:0098656 77 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
cellular cation homeostasis GO:0030003 180 0.012
regulation of cell projection organization GO:0031344 175 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
gliogenesis GO:0042063 93 0.012
muscle structure development GO:0061061 87 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of metal ion transport GO:0010959 118 0.012
dna metabolic process GO:0006259 96 0.012
multicellular organismal homeostasis GO:0048871 49 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
response to toxic substance GO:0009636 133 0.012
response to wounding GO:0009611 254 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
cellular response to biotic stimulus GO:0071216 59 0.012
calcium ion homeostasis GO:0055074 162 0.012
blood circulation GO:0008015 183 0.012
positive regulation of ion transport GO:0043270 94 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
organic anion transport GO:0015711 132 0.012
peptidyl amino acid modification GO:0018193 126 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
glucose homeostasis GO:0042593 75 0.012
negative regulation of transport GO:0051051 136 0.011
salivary gland development GO:0007431 3 0.011
negative regulation of developmental process GO:0051093 125 0.011
response to estradiol GO:0032355 164 0.011
peptide transport GO:0015833 97 0.011
proteolysis GO:0006508 175 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
divalent metal ion transport GO:0070838 132 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
regulation of neuron differentiation GO:0045664 208 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
heterocycle catabolic process GO:0046700 167 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
secretion by cell GO:0032940 248 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
regulation of transmembrane transport GO:0034762 122 0.011
calcium ion transport GO:0006816 131 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
response to interleukin 1 GO:0070555 55 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
maintenance of location GO:0051235 17 0.011
axonogenesis GO:0007409 71 0.011
camera type eye morphogenesis GO:0048593 2 0.011
neural crest cell differentiation GO:0014033 2 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
cell cycle GO:0007049 101 0.011
mesoderm development GO:0007498 2 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
olfactory behavior GO:0042048 2 0.011
ossification GO:0001503 70 0.010
synaptic vesicle endocytosis GO:0048488 4 0.010
signal release GO:0023061 145 0.010
response to reactive oxygen species GO:0000302 120 0.010
regulation of calcium ion transport GO:0051924 77 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
retina morphogenesis in camera type eye GO:0060042 1 0.010
positive regulation of transport GO:0051050 245 0.010
positive regulation of catabolic process GO:0009896 78 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
response to purine containing compound GO:0014074 126 0.010
response to vitamin GO:0033273 131 0.010
single organism cell adhesion GO:0098602 46 0.010
regulation of organelle organization GO:0033043 80 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
nucleotide catabolic process GO:0009166 139 0.010
neuromuscular process GO:0050905 2 0.010
muscle tissue development GO:0060537 58 0.010
organophosphate catabolic process GO:0046434 148 0.010
gamete generation GO:0007276 124 0.010
muscle system process GO:0003012 115 0.010
gland development GO:0048732 155 0.010
response to temperature stimulus GO:0009266 94 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010

Lrrc8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010