Rattus norvegicus

109 known processes

Sox2

SRY (sex determining region Y)-box 2

(Aliases: RGD1565646)

Sox2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.195
positive regulation of phosphate metabolic process GO:0045937 262 0.130
ion transmembrane transport GO:0034220 365 0.118
central nervous system development GO:0007417 311 0.111
regulation of cellular component organization GO:0051128 368 0.103
regulation of rna biosynthetic process GO:2001141 381 0.098
response to metal ion GO:0010038 253 0.097
regulation of ion transport GO:0043269 245 0.096
positive regulation of signaling GO:0023056 270 0.090
nucleotide metabolic process GO:0009117 279 0.087
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.086
intracellular transport GO:0046907 185 0.085
cardiac muscle contraction GO:0060048 27 0.083
cell projection organization GO:0030030 302 0.081
muscle system process GO:0003012 115 0.080
cellular component biogenesis GO:0044085 368 0.077
anion transport GO:0006820 178 0.076
response to inorganic substance GO:0010035 377 0.072
regulation of nucleic acid templated transcription GO:1903506 380 0.071
purine ribonucleotide metabolic process GO:0009150 227 0.070
regulation of rna metabolic process GO:0051252 391 0.070
positive regulation of response to stimulus GO:0048584 285 0.070
regulation of mapk cascade GO:0043408 116 0.069
ribonucleotide metabolic process GO:0009259 231 0.069
regulation of catalytic activity GO:0050790 304 0.069
neuron differentiation GO:0030182 368 0.069
brain development GO:0007420 247 0.068
cellular response to hormone stimulus GO:0032870 247 0.068
transcription dna templated GO:0006351 377 0.066
regulation of phosphate metabolic process GO:0019220 349 0.064
transmembrane transport GO:0055085 412 0.064
inorganic ion transmembrane transport GO:0098660 229 0.063
purine containing compound metabolic process GO:0072521 253 0.062
rna biosynthetic process GO:0032774 380 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.061
cellular component assembly GO:0022607 360 0.060
positive regulation of intracellular signal transduction GO:1902533 138 0.059
regulation of phosphorus metabolic process GO:0051174 349 0.058
organophosphate metabolic process GO:0019637 370 0.057
nitrogen compound transport GO:0071705 229 0.057
behavior GO:0007610 205 0.057
negative regulation of nervous system development GO:0051961 79 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
neuron development GO:0048666 286 0.054
regulation of molecular function GO:0065009 398 0.054
nucleobase containing small molecule metabolic process GO:0055086 316 0.054
rna metabolic process GO:0016070 406 0.054
response to estradiol GO:0032355 164 0.054
cellular response to oxygen containing compound GO:1901701 386 0.053
positive regulation of signal transduction GO:0009967 175 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.052
positive regulation of gene expression GO:0010628 244 0.051
negative regulation of developmental process GO:0051093 125 0.051
organic anion transport GO:0015711 132 0.051
carboxylic acid transport GO:0046942 115 0.050
negative regulation of transport GO:0051051 136 0.050
aging GO:0007568 241 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
lipid metabolic process GO:0006629 283 0.049
ribose phosphate metabolic process GO:0019693 235 0.049
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.049
negative regulation of metabolic process GO:0009892 331 0.048
muscle contraction GO:0006936 88 0.048
hair follicle development GO:0001942 2 0.048
cellular response to endogenous stimulus GO:0071495 377 0.047
regulation of signal transduction GO:0009966 318 0.046
purine nucleotide metabolic process GO:0006163 229 0.046
cellular response to stress GO:0033554 269 0.046
cardiac chamber development GO:0003205 1 0.045
head development GO:0060322 247 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
positive regulation of secretion GO:0051047 140 0.045
negative regulation of biosynthetic process GO:0009890 168 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
cellular response to nitrogen compound GO:1901699 210 0.045
negative regulation of cell development GO:0010721 82 0.044
cellular response to organic cyclic compound GO:0071407 202 0.043
response to glucocorticoid GO:0051384 223 0.043
nucleic acid templated transcription GO:0097659 379 0.043
cellular lipid metabolic process GO:0044255 208 0.042
mapk cascade GO:0000165 140 0.042
chemical homeostasis GO:0048878 292 0.041
cation transmembrane transport GO:0098655 263 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
divalent inorganic cation transport GO:0072511 134 0.041
monocarboxylic acid metabolic process GO:0032787 152 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.040
regulation of muscle contraction GO:0006937 53 0.040
negative regulation of multicellular organismal process GO:0051241 203 0.040
positive regulation of cell communication GO:0010647 271 0.040
cell cell signaling GO:0007267 335 0.040
response to corticosteroid GO:0031960 235 0.040
transmission of nerve impulse GO:0019226 42 0.040
response to cytokine GO:0034097 215 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.039
divalent metal ion transport GO:0070838 132 0.039
metal ion transport GO:0030001 289 0.039
purine nucleotide catabolic process GO:0006195 136 0.039
organelle organization GO:0006996 266 0.038
gliogenesis GO:0042063 93 0.038
regulation of intracellular signal transduction GO:1902531 218 0.038
striated muscle contraction GO:0006941 44 0.038
positive regulation of biosynthetic process GO:0009891 319 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.038
chemotaxis GO:0006935 66 0.036
positive regulation of nucleotide metabolic process GO:0045981 91 0.036
regulation of hydrolase activity GO:0051336 143 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
regulation of cell development GO:0060284 263 0.035
striated muscle tissue development GO:0014706 58 0.035
cation transport GO:0006812 382 0.035
regulation of nervous system development GO:0051960 264 0.035
negative regulation of cell differentiation GO:0045596 99 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.034
developmental process involved in reproduction GO:0003006 159 0.034
purine containing compound catabolic process GO:0072523 138 0.034
defense response GO:0006952 194 0.034
negative regulation of neuron differentiation GO:0045665 62 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
regulation of phosphorylation GO:0042325 248 0.034
negative regulation of neurogenesis GO:0050768 78 0.033
enzyme linked receptor protein signaling pathway GO:0007167 116 0.033
regulation of cell proliferation GO:0042127 359 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
organic acid transport GO:0015849 116 0.033
vesicle mediated transport GO:0016192 181 0.033
single organism organelle organization GO:1902589 180 0.033
positive regulation of rna metabolic process GO:0051254 203 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.032
cellular cation homeostasis GO:0030003 180 0.032
response to estrogen GO:0043627 232 0.032
forebrain development GO:0030900 98 0.031
macromolecular complex assembly GO:0065003 273 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
response to ketone GO:1901654 182 0.031
protein complex assembly GO:0006461 263 0.031
regulation of purine nucleotide metabolic process GO:1900542 115 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.030
ribonucleotide catabolic process GO:0009261 136 0.030
hormone transport GO:0009914 121 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
mesoderm development GO:0007498 2 0.030
cellular homeostasis GO:0019725 252 0.030
negative regulation of cell communication GO:0010648 158 0.029
regulation of secretion by cell GO:1903530 208 0.029
reproductive process GO:0022414 372 0.029
inflammatory response GO:0006954 150 0.029
response to growth factor GO:0070848 189 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
ion homeostasis GO:0050801 212 0.028
single organism behavior GO:0044708 130 0.028
regulation of muscle system process GO:0090257 79 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.027
heart contraction GO:0060047 57 0.027
positive regulation of nervous system development GO:0051962 178 0.027
regulation of nucleotide metabolic process GO:0006140 117 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.027
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
single organism reproductive process GO:0044702 297 0.026
cellular response to abiotic stimulus GO:0071214 85 0.026
regulation of neurogenesis GO:0050767 247 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.026
ribonucleoside catabolic process GO:0042454 126 0.026
organophosphate catabolic process GO:0046434 148 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
positive regulation of molecular function GO:0044093 230 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
protein phosphorylation GO:0006468 345 0.024
purine nucleoside triphosphate catabolic process GO:0009146 122 0.024
muscle tissue development GO:0060537 58 0.024
regulation of ion transmembrane transport GO:0034765 121 0.024
unsaturated fatty acid metabolic process GO:0033559 39 0.024
regulation of system process GO:0044057 208 0.024
nucleoside catabolic process GO:0009164 126 0.024
multicellular organismal signaling GO:0035637 44 0.024
action potential GO:0001508 54 0.023
response to nutrient levels GO:0031667 370 0.023
regulation of secretion GO:0051046 224 0.023
negative regulation of signaling GO:0023057 157 0.023
ras protein signal transduction GO:0007265 29 0.023
regulation of cellular localization GO:0060341 263 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
nucleobase containing compound catabolic process GO:0034655 152 0.023
axis specification GO:0009798 4 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
ribonucleoside triphosphate catabolic process GO:0009203 122 0.023
ribonucleotide biosynthetic process GO:0009260 85 0.023
cation homeostasis GO:0055080 195 0.023
multicellular organism reproduction GO:0032504 233 0.023
positive regulation of secretion by cell GO:1903532 128 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
telencephalon development GO:0021537 62 0.022
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.022
nucleoside metabolic process GO:0009116 179 0.022
dephosphorylation GO:0016311 98 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
secretion GO:0046903 307 0.022
protein complex biogenesis GO:0070271 263 0.022
neuron projection development GO:0031175 273 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
glial cell differentiation GO:0010001 65 0.021
response to peptide GO:1901652 292 0.021
regulation of synaptic transmission GO:0050804 141 0.021
cell part morphogenesis GO:0032990 123 0.021
camp biosynthetic process GO:0006171 47 0.021
regulation of synaptic transmission glutamatergic GO:0051966 26 0.021
nucleotide catabolic process GO:0009166 139 0.021
regulation of nucleotide biosynthetic process GO:0030808 47 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
cellular chemical homeostasis GO:0055082 247 0.021
protein localization GO:0008104 191 0.021
response to mineralocorticoid GO:0051385 49 0.021
cellular response to external stimulus GO:0071496 118 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
smooth muscle contraction GO:0006939 37 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
cellular component movement GO:0006928 248 0.021
macromolecule localization GO:0033036 252 0.021
monocarboxylic acid biosynthetic process GO:0072330 48 0.020
metal ion homeostasis GO:0055065 186 0.020
regulation of protein metabolic process GO:0051246 289 0.020
heart morphogenesis GO:0003007 3 0.020
cardiac muscle cell contraction GO:0086003 10 0.020
regulation of calcium ion transport GO:0051924 77 0.020
negative regulation of gene expression GO:0010629 199 0.020
calcium ion transport GO:0006816 131 0.020
neurological system process GO:0050877 219 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
ribose phosphate biosynthetic process GO:0046390 87 0.020
regulation of map kinase activity GO:0043405 53 0.020
single organism intracellular transport GO:1902582 166 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
secretion by cell GO:0032940 248 0.020
positive regulation of synaptic transmission GO:0050806 62 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
nucleoside triphosphate catabolic process GO:0009143 123 0.020
cell projection morphogenesis GO:0048858 123 0.020
purine ribonucleotide biosynthetic process GO:0009152 81 0.019
glutamate receptor signaling pathway GO:0007215 43 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
insulin secretion GO:0030073 69 0.019
bmp signaling pathway GO:0030509 4 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
protein complex subunit organization GO:0071822 302 0.019
localization of cell GO:0051674 202 0.019
regulation of metal ion transport GO:0010959 118 0.019
lipid biosynthetic process GO:0008610 128 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
camp metabolic process GO:0046058 63 0.019
blood circulation GO:0008015 183 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
purine containing compound biosynthetic process GO:0072522 85 0.019
icosanoid metabolic process GO:0006690 38 0.019
inorganic cation transmembrane transport GO:0098662 202 0.018
regulation of protein modification process GO:0031399 194 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.018
cellular macromolecule localization GO:0070727 122 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
fatty acid metabolic process GO:0006631 99 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
actin mediated cell contraction GO:0070252 12 0.018
sex differentiation GO:0007548 113 0.018
respiratory system process GO:0003016 3 0.018
actin filament based process GO:0030029 86 0.018
circulatory system development GO:0072359 134 0.018
single organism catabolic process GO:0044712 283 0.018
cyclic nucleotide biosynthetic process GO:0009190 63 0.018
apoptotic process GO:0006915 381 0.018
response to decreased oxygen levels GO:0036293 237 0.018
organic acid biosynthetic process GO:0016053 83 0.017
regulation of camp biosynthetic process GO:0030817 38 0.017
cellular ketone metabolic process GO:0042180 51 0.017
catabolic process GO:0009056 351 0.017
neuromuscular process GO:0050905 2 0.017
regulation of apoptotic process GO:0042981 335 0.017
hair cycle GO:0042633 3 0.017
catecholamine transport GO:0051937 37 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
single organism biosynthetic process GO:0044711 342 0.017
response to ammonium ion GO:0060359 71 0.017
regulation of cell differentiation GO:0045595 320 0.017
calcium ion transmembrane transport GO:0070588 70 0.017
response to radiation GO:0009314 137 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
negative regulation of ion transport GO:0043271 51 0.016
gastrulation GO:0007369 2 0.016
rhythmic process GO:0048511 156 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
organ formation GO:0048645 3 0.016
response to reactive oxygen species GO:0000302 120 0.016
oxoacid metabolic process GO:0043436 290 0.016
synaptic transmission GO:0007268 235 0.016
choline transport GO:0015871 4 0.016
regulation of cell projection organization GO:0031344 175 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
negative regulation of cell projection organization GO:0031345 50 0.016
cellular ion homeostasis GO:0006873 184 0.016
regulation of neuron projection development GO:0010975 161 0.016
axon development GO:0061564 96 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
regulation of neuron differentiation GO:0045664 208 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
response to hexose GO:0009746 144 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of transport GO:0051050 245 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
purine nucleotide biosynthetic process GO:0006164 83 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
heart process GO:0003015 57 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.016
response to toxic substance GO:0009636 133 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
learning or memory GO:0007611 90 0.015
response to hypoxia GO:0001666 231 0.015
cardiac ventricle development GO:0003231 1 0.015
response to monosaccharide GO:0034284 159 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of programmed cell death GO:0043067 341 0.015
aromatic compound catabolic process GO:0019439 168 0.015
regulation of camp metabolic process GO:0030814 43 0.015
urinary tract smooth muscle contraction GO:0014848 4 0.015
potassium ion transport GO:0006813 97 0.015
cell morphogenesis GO:0000902 142 0.015
multi organism reproductive process GO:0044703 262 0.015
positive regulation of map kinase activity GO:0043406 46 0.015
molting cycle process GO:0022404 2 0.015
regulation of heart contraction GO:0008016 48 0.015
regulation of transcription dna templated GO:0006355 374 0.015
cellular amine metabolic process GO:0044106 38 0.015
heart development GO:0007507 72 0.015
multi multicellular organism process GO:0044706 138 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
negative regulation of cell death GO:0060548 229 0.015
neuron projection morphogenesis GO:0048812 122 0.014
negative regulation of developmental growth GO:0048640 15 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
lipid localization GO:0010876 62 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
positive regulation of cell development GO:0010720 176 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
programmed cell death GO:0012501 392 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
cardiovascular system development GO:0072358 134 0.014
response to peptide hormone GO:0043434 278 0.014
sexual reproduction GO:0019953 148 0.014
protein transport GO:0015031 132 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
muscle structure development GO:0061061 87 0.014
peptide secretion GO:0002790 86 0.014
hair cycle process GO:0022405 2 0.014
regulation of gtpase activity GO:0043087 57 0.014
multicellular organism growth GO:0035264 1 0.014
response to wounding GO:0009611 254 0.014
negative regulation of molecular function GO:0044092 133 0.014
heterocycle catabolic process GO:0046700 167 0.014
potassium ion transmembrane transport GO:0071805 71 0.014
erk1 and erk2 cascade GO:0070371 48 0.014
signal release GO:0023061 145 0.014
positive regulation of transferase activity GO:0051347 81 0.014
response to extracellular stimulus GO:0009991 380 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
reproductive system development GO:0061458 128 0.013
autonomic nervous system development GO:0048483 3 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.013
homeostatic process GO:0042592 331 0.013
locomotion GO:0040011 237 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
regulation of receptor activity GO:0010469 29 0.013
positive regulation of protein tyrosine kinase activity GO:0061098 2 0.013
amine metabolic process GO:0009308 38 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
reproductive structure development GO:0048608 128 0.013
single organism membrane organization GO:0044802 74 0.013
response to testosterone GO:0033574 55 0.013
molting cycle GO:0042303 3 0.013
regulation of cell cycle GO:0051726 73 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
calcium ion homeostasis GO:0055074 162 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
regulation of bmp signaling pathway GO:0030510 2 0.013
cellular macromolecular complex assembly GO:0034622 58 0.013
regulation of homeostatic process GO:0032844 101 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
fatty acid derivative metabolic process GO:1901568 38 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
l glutamate import GO:0051938 2 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
positive regulation of ion transport GO:0043270 94 0.013
negative regulation of neuron projection development GO:0010977 46 0.013
gonad development GO:0008406 104 0.013
epithelial cell differentiation GO:0030855 71 0.012
regulation of hormone levels GO:0010817 187 0.012
memory GO:0007613 54 0.012
peptide transport GO:0015833 97 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
regulation of kinase activity GO:0043549 117 0.012
circadian rhythm GO:0007623 88 0.012
positive regulation of receptor activity GO:2000273 4 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
muscle cell proliferation GO:0033002 84 0.012
liver development GO:0001889 90 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
developmental growth GO:0048589 100 0.012
regulation of organelle organization GO:0033043 80 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
circulatory system process GO:0003013 183 0.012
monoamine transport GO:0015844 43 0.012
calcium mediated signaling GO:0019722 23 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.012
lipid storage GO:0019915 1 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
pallium development GO:0021543 42 0.012
muscle tissue morphogenesis GO:0060415 1 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
negative regulation of camp metabolic process GO:0030815 14 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
cellular protein complex assembly GO:0043623 44 0.012
regulation of catecholamine secretion GO:0050433 32 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
protein homooligomerization GO:0051260 91 0.012
amide transport GO:0042886 105 0.012
regulation of anatomical structure size GO:0090066 135 0.011
protein oligomerization GO:0051259 191 0.011
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
regulation of ion homeostasis GO:2000021 63 0.011
anterior posterior pattern specification GO:0009952 1 0.011
formation of primary germ layer GO:0001704 1 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
single organism cell adhesion GO:0098602 46 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
glucose homeostasis GO:0042593 75 0.011
cellular component morphogenesis GO:0032989 155 0.011
regulation of cellular component movement GO:0051270 150 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of smooth muscle contraction GO:0006940 29 0.011
gtp metabolic process GO:0046039 72 0.011
response to carbohydrate GO:0009743 183 0.011
organic acid metabolic process GO:0006082 292 0.011
single organismal cell cell adhesion GO:0016337 42 0.011
positive regulation of protein modification process GO:0031401 142 0.011
male sex differentiation GO:0046661 64 0.011
salivary gland development GO:0007431 3 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
cellular catabolic process GO:0044248 295 0.011
acid secretion GO:0046717 48 0.011
negative regulation of secretion GO:0051048 82 0.011
response to external biotic stimulus GO:0043207 221 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.011
positive regulation of organelle organization GO:0010638 48 0.011
endocytosis GO:0006897 84 0.011
monocarboxylic acid transport GO:0015718 52 0.011
guanosine containing compound catabolic process GO:1901069 71 0.010
response to oxygen levels GO:0070482 265 0.010
regulation of transporter activity GO:0032409 50 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
anion transmembrane transport GO:0098656 77 0.010
response to nutrient GO:0007584 248 0.010
ensheathment of neurons GO:0007272 40 0.010
cell activation GO:0001775 97 0.010
skeletal muscle tissue development GO:0007519 31 0.010
establishment of organelle localization GO:0051656 37 0.010
cytoplasmic transport GO:0016482 115 0.010
dicarboxylic acid transport GO:0006835 34 0.010
phosphatidylinositol dephosphorylation GO:0046856 4 0.010

Sox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.126
musculoskeletal system disease DOID:17 0 0.126
nervous system disease DOID:863 0 0.039
sensory system disease DOID:0050155 0 0.024
connective tissue disease DOID:65 0 0.017
disease of cellular proliferation DOID:14566 0 0.016
bone disease DOID:0080001 0 0.016
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.012
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010