Rattus norvegicus

0 known processes

Enpp4

ectonucleotide pyrophosphatase/phosphodiesterase 4

Enpp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein phosphorylation GO:0006468 345 0.056
intracellular signal transduction GO:0035556 314 0.056
organophosphate metabolic process GO:0019637 370 0.055
Yeast Rat
regulation of phosphorus metabolic process GO:0051174 349 0.054
cellular catabolic process GO:0044248 295 0.052
Human Rat
response to inorganic substance GO:0010035 377 0.050
organic acid metabolic process GO:0006082 292 0.048
carbohydrate derivative metabolic process GO:1901135 346 0.046
Human
carboxylic acid metabolic process GO:0019752 289 0.046
regulation of phosphate metabolic process GO:0019220 349 0.044
single organism catabolic process GO:0044712 283 0.044
Human Rat
purine containing compound metabolic process GO:0072521 253 0.044
Human
cellular amino acid metabolic process GO:0006520 107 0.043
cellular component biogenesis GO:0044085 368 0.041
cellular lipid metabolic process GO:0044255 208 0.040
Rat
regulation of intracellular signal transduction GO:1902531 218 0.040
cation transport GO:0006812 382 0.038
central nervous system development GO:0007417 311 0.036
oxoacid metabolic process GO:0043436 290 0.035
amine metabolic process GO:0009308 38 0.034
Rat
catabolic process GO:0009056 351 0.034
Human Rat
ribose phosphate metabolic process GO:0019693 235 0.033
organophosphate catabolic process GO:0046434 148 0.033
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.032
Yeast
organic substance catabolic process GO:1901575 316 0.032
Human Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
response to metal ion GO:0010038 253 0.031
establishment of protein localization GO:0045184 141 0.030
protein complex biogenesis GO:0070271 263 0.030
small gtpase mediated signal transduction GO:0007264 36 0.029
regulation of catalytic activity GO:0050790 304 0.029
regulation of signal transduction GO:0009966 318 0.029
protein localization GO:0008104 191 0.029
cellular amine metabolic process GO:0044106 38 0.029
Rat
nucleotide metabolic process GO:0009117 279 0.029
regulation of molecular function GO:0065009 398 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
single organism intracellular transport GO:1902582 166 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
neuron development GO:0048666 286 0.028
intracellular transport GO:0046907 185 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
protein complex subunit organization GO:0071822 302 0.028
cellular ketone metabolic process GO:0042180 51 0.028
neuron differentiation GO:0030182 368 0.028
regulation of cellular component organization GO:0051128 368 0.027
transmembrane transport GO:0055085 412 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
cellular component movement GO:0006928 248 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
Human
organonitrogen compound catabolic process GO:1901565 179 0.027
Human Rat
protein complex assembly GO:0006461 263 0.027
negative regulation of transport GO:0051051 136 0.027
regulation of cell projection organization GO:0031344 175 0.026
regulation of protein modification process GO:0031399 194 0.026
programmed cell death GO:0012501 392 0.026
aromatic compound catabolic process GO:0019439 168 0.026
Human
regulation of neurogenesis GO:0050767 247 0.025
cell projection organization GO:0030030 302 0.025
cell cell signaling GO:0007267 335 0.025
head development GO:0060322 247 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
neuron projection development GO:0031175 273 0.024
cellular component assembly GO:0022607 360 0.024
regulation of neuron projection development GO:0010975 161 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of neuron differentiation GO:0045664 208 0.024
nitrogen compound transport GO:0071705 229 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
regulation of apoptotic process GO:0042981 335 0.023
lipid metabolic process GO:0006629 283 0.023
Rat
regulation of multicellular organismal development GO:2000026 376 0.023
cell migration GO:0016477 197 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
regulation of programmed cell death GO:0043067 341 0.023
macromolecular complex assembly GO:0065003 273 0.023
ras protein signal transduction GO:0007265 29 0.022
cation transmembrane transport GO:0098655 263 0.022
regulation of cellular localization GO:0060341 263 0.022
regulation of phosphorylation GO:0042325 248 0.022
neuronal action potential GO:0019228 35 0.022
cellular response to stress GO:0033554 269 0.022
Yeast
positive regulation of cell proliferation GO:0008284 249 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
response to wounding GO:0009611 254 0.021
Human
ribonucleoside catabolic process GO:0042454 126 0.021
Human
secretion by cell GO:0032940 248 0.021
multicellular organismal signaling GO:0035637 44 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
heterocycle catabolic process GO:0046700 167 0.020
Human
homeostatic process GO:0042592 331 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
brain development GO:0007420 247 0.020
nucleoside metabolic process GO:0009116 179 0.020
Human
transmission of nerve impulse GO:0019226 42 0.020
regulation of protein metabolic process GO:0051246 289 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
positive regulation of molecular function GO:0044093 230 0.020
response to extracellular stimulus GO:0009991 380 0.020
Yeast
positive regulation of cell projection organization GO:0031346 111 0.020
response to acid chemical GO:0001101 222 0.020
response to estradiol GO:0032355 164 0.020
ion transmembrane transport GO:0034220 365 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
Human Yeast
anion transport GO:0006820 178 0.019
negative regulation of cell communication GO:0010648 158 0.019
negative regulation of metabolic process GO:0009892 331 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
single organism biosynthetic process GO:0044711 342 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
Human
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
cell motility GO:0048870 202 0.019
macromolecule localization GO:0033036 252 0.019
response to nutrient levels GO:0031667 370 0.019
Yeast
organic cyclic compound catabolic process GO:1901361 175 0.019
Human
purine nucleoside metabolic process GO:0042278 169 0.019
Human
cardiovascular system development GO:0072358 134 0.019
regulation of canonical wnt signaling pathway GO:0060828 4 0.019
positive regulation of developmental process GO:0051094 283 0.019
mapk cascade GO:0000165 140 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.018
apoptotic process GO:0006915 381 0.018
response to peptide hormone GO:0043434 278 0.018
aging GO:0007568 241 0.018
action potential GO:0001508 54 0.018
negative regulation of signaling GO:0023057 157 0.018
regulation of cell differentiation GO:0045595 320 0.018
nucleotide catabolic process GO:0009166 139 0.018
response to bacterium GO:0009617 200 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
secretion GO:0046903 307 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
macromolecular complex subunit organization GO:0043933 339 0.017
regulation of mapk cascade GO:0043408 116 0.017
regulation of membrane potential GO:0042391 110 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
regulation of nervous system development GO:0051960 264 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
synaptic transmission GO:0007268 235 0.017
protein transport GO:0015031 132 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
metal ion transport GO:0030001 289 0.017
positive regulation of transport GO:0051050 245 0.017
neurological system process GO:0050877 219 0.017
regulation of hydrolase activity GO:0051336 143 0.017
positive regulation of biosynthetic process GO:0009891 319 0.016
response to growth factor GO:0070848 189 0.016
potassium ion transport GO:0006813 97 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
Human
purine ribonucleotide catabolic process GO:0009154 136 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
response to estrogen GO:0043627 232 0.016
localization of cell GO:0051674 202 0.016
regulation of transferase activity GO:0051338 123 0.015
cell morphogenesis GO:0000902 142 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of catabolic process GO:0009894 113 0.015
protein oligomerization GO:0051259 191 0.015
response to other organism GO:0051707 220 0.015
organic anion transport GO:0015711 132 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
single organism organelle organization GO:1902589 180 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
glycerolipid metabolic process GO:0046486 67 0.015
Rat
organic acid transport GO:0015849 116 0.015
circulatory system development GO:0072359 134 0.015
organelle organization GO:0006996 266 0.015
cytoplasmic transport GO:0016482 115 0.015
cell cycle GO:0007049 101 0.015
cellular protein localization GO:0034613 122 0.015
anterior posterior pattern specification GO:0009952 1 0.015
nucleoside catabolic process GO:0009164 126 0.015
Human
regulation of secretion by cell GO:1903530 208 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
regulation of secretion GO:0051046 224 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
muscle system process GO:0003012 115 0.014
negative regulation of cell death GO:0060548 229 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
response to carbohydrate GO:0009743 183 0.014
rna metabolic process GO:0016070 406 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
response to reactive oxygen species GO:0000302 120 0.014
cellular macromolecule localization GO:0070727 122 0.014
regulation of rna metabolic process GO:0051252 391 0.014
ensheathment of neurons GO:0007272 40 0.014
regulation of cell development GO:0060284 263 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
protein heterooligomerization GO:0051291 89 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
vesicle mediated transport GO:0016192 181 0.014
response to nutrient GO:0007584 248 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
response to external biotic stimulus GO:0043207 221 0.014
response to lipopolysaccharide GO:0032496 191 0.014
regulation of synaptic transmission GO:0050804 141 0.014
positive regulation of signaling GO:0023056 270 0.014
eye morphogenesis GO:0048592 4 0.013
heart morphogenesis GO:0003007 3 0.013
positive regulation of cell development GO:0010720 176 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
Human
cellular response to growth factor stimulus GO:0071363 162 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
Yeast
response to peptide GO:1901652 292 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
Human
protein targeting GO:0006605 61 0.013
regulation of protein kinase activity GO:0045859 105 0.013
purine containing compound catabolic process GO:0072523 138 0.013
Human
purine nucleoside catabolic process GO:0006152 124 0.013
Human
inorganic ion transmembrane transport GO:0098660 229 0.013
gastrulation GO:0007369 2 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
axon ensheathment GO:0008366 40 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
mesoderm development GO:0007498 2 0.013
immune system process GO:0002376 204 0.013
response to oxygen levels GO:0070482 265 0.012
regulation of kinase activity GO:0043549 117 0.012
axis specification GO:0009798 4 0.012
forebrain development GO:0030900 98 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
Human
protein homooligomerization GO:0051260 91 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
positive regulation of protein modification process GO:0031401 142 0.012
reproductive process GO:0022414 372 0.012
growth GO:0040007 165 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
regulation of transcription dna templated GO:0006355 374 0.012
cellular response to lipid GO:0071396 201 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
Human
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
response to radiation GO:0009314 137 0.011
multi organism reproductive process GO:0044703 262 0.011
response to decreased oxygen levels GO:0036293 237 0.011
response to hydrogen peroxide GO:0042542 89 0.011
spindle organization GO:0007051 2 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
cellular homeostasis GO:0019725 252 0.011
positive regulation of signal transduction GO:0009967 175 0.011
response to monosaccharide GO:0034284 159 0.011
response to glucocorticoid GO:0051384 223 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of transcription factor import into nucleus GO:0042993 4 0.011
response to corticosteroid GO:0031960 235 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
cell part morphogenesis GO:0032990 123 0.011
cell projection morphogenesis GO:0048858 123 0.011
response to cytokine GO:0034097 215 0.011
regulation of cell proliferation GO:0042127 359 0.011
chemical homeostasis GO:0048878 292 0.011
dephosphorylation GO:0016311 98 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of response to external stimulus GO:0032101 106 0.011
Human
single organism cellular localization GO:1902580 102 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to hypoxia GO:0001666 231 0.011
regulation of response to stress GO:0080134 126 0.011
Human
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
chromosome segregation GO:0007059 2 0.010
defense response GO:0006952 194 0.010
gliogenesis GO:0042063 93 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
Human
response to ethanol GO:0045471 162 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
transcription dna templated GO:0006351 377 0.010
multicellular organism reproduction GO:0032504 233 0.010
behavior GO:0007610 205 0.010
heart development GO:0007507 72 0.010
calcium ion transport GO:0006816 131 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
proteolysis GO:0006508 175 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
response to biotic stimulus GO:0009607 226 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010

Enpp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.011