Rattus norvegicus

63 known processes

Bmp15

bone morphogenetic protein 15

(Aliases: Gdf-9b)

Bmp15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.441
Rat
regulation of molecular function GO:0065009 398 0.221
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.142
regulation of cellular protein metabolic process GO:0032268 267 0.126
transmembrane transport GO:0055085 412 0.123
vesicle mediated transport GO:0016192 181 0.111
neuron development GO:0048666 286 0.106
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.098
cation transmembrane transport GO:0098655 263 0.098
regulation of phosphorus metabolic process GO:0051174 349 0.095
Rat
positive regulation of developmental process GO:0051094 283 0.092
Rat
regulation of protein metabolic process GO:0051246 289 0.090
positive regulation of gene expression GO:0010628 244 0.090
positive regulation of biosynthetic process GO:0009891 319 0.088
vascular process in circulatory system GO:0003018 96 0.088
circulatory system process GO:0003013 183 0.087
regulation of multicellular organismal development GO:2000026 376 0.082
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.081
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.074
positive regulation of phosphorus metabolic process GO:0010562 262 0.071
response to extracellular stimulus GO:0009991 380 0.067
Rat
positive regulation of cell differentiation GO:0045597 217 0.067
Rat
protein phosphorylation GO:0006468 345 0.065
regulation of catalytic activity GO:0050790 304 0.065
response to inorganic substance GO:0010035 377 0.064
Rat
anion transport GO:0006820 178 0.064
inorganic ion transmembrane transport GO:0098660 229 0.063
growth GO:0040007 165 0.063
cell projection organization GO:0030030 302 0.062
multicellular organismal reproductive process GO:0048609 233 0.062
Zebrafish Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
cellular response to endogenous stimulus GO:0071495 377 0.059
positive regulation of catalytic activity GO:0043085 184 0.059
transcription from rna polymerase ii promoter GO:0006366 252 0.059
single organism reproductive process GO:0044702 297 0.058
Zebrafish Rat
ion transmembrane transport GO:0034220 365 0.057
regulation of phosphate metabolic process GO:0019220 349 0.057
Rat
cell cell signaling GO:0007267 335 0.056
positive regulation of nervous system development GO:0051962 178 0.055
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
negative regulation of macromolecule metabolic process GO:0010605 260 0.052
regulation of protein modification process GO:0031399 194 0.051
male sex differentiation GO:0046661 64 0.048
protein oligomerization GO:0051259 191 0.046
cellular cation homeostasis GO:0030003 180 0.046
renal system development GO:0072001 67 0.045
regulation of growth GO:0040008 105 0.044
tissue development GO:0009888 252 0.043
regulation of cell proliferation GO:0042127 359 0.043
metal ion transport GO:0030001 289 0.042
mesonephros development GO:0001823 14 0.042
cell morphogenesis GO:0000902 142 0.042
cellular homeostasis GO:0019725 252 0.041
neuron projection development GO:0031175 273 0.041
muscle system process GO:0003012 115 0.041
Rat
regulation of neuron differentiation GO:0045664 208 0.039
anatomical structure morphogenesis GO:0009653 298 0.039
Rat
regulation of anatomical structure size GO:0090066 135 0.039
homeostatic process GO:0042592 331 0.039
secretion by cell GO:0032940 248 0.039
negative regulation of programmed cell death GO:0043069 183 0.039
Rat
single organism intracellular transport GO:1902582 166 0.039
Rat
organelle organization GO:0006996 266 0.038
Rat
intracellular transport GO:0046907 185 0.038
Rat
neurological system process GO:0050877 219 0.038
negative regulation of cell death GO:0060548 229 0.037
Rat
cell part morphogenesis GO:0032990 123 0.037
cell type specific apoptotic process GO:0097285 134 0.037
Rat
regulation of system process GO:0044057 208 0.037
Rat
regulation of phosphorylation GO:0042325 248 0.037
Rat
response to metal ion GO:0010038 253 0.035
macromolecule localization GO:0033036 252 0.035
Rat
regulation of nervous system development GO:0051960 264 0.035
cell motility GO:0048870 202 0.035
regulation of ion transport GO:0043269 245 0.035
positive regulation of cell proliferation GO:0008284 249 0.034
camera type eye development GO:0043010 48 0.034
positive regulation of transport GO:0051050 245 0.034
regulation of cell differentiation GO:0045595 320 0.034
Zebrafish Rat
positive regulation of neuron differentiation GO:0045666 126 0.033
negative regulation of metabolic process GO:0009892 331 0.033
positive regulation of signaling GO:0023056 270 0.033
response to hypoxia GO:0001666 231 0.033
Rat
negative regulation of molecular function GO:0044092 133 0.033
Rat
cellular amine metabolic process GO:0044106 38 0.032
response to decreased oxygen levels GO:0036293 237 0.032
Rat
positive regulation of phosphorylation GO:0042327 177 0.032
carbohydrate derivative catabolic process GO:1901136 147 0.032
protein localization GO:0008104 191 0.031
Rat
behavior GO:0007610 205 0.031
programmed cell death GO:0012501 392 0.031
Rat
regulation of cellular component organization GO:0051128 368 0.031
positive regulation of protein phosphorylation GO:0001934 135 0.031
positive regulation of molecular function GO:0044093 230 0.031
cation homeostasis GO:0055080 195 0.031
rna metabolic process GO:0016070 406 0.031
secretion GO:0046903 307 0.030
locomotion GO:0040011 237 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
cellular ion homeostasis GO:0006873 184 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
protein complex assembly GO:0006461 263 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
sensory organ development GO:0007423 74 0.030
signal transduction by phosphorylation GO:0023014 144 0.030
positive regulation of neurogenesis GO:0050769 165 0.029
positive regulation of cell projection organization GO:0031346 111 0.029
macromolecular complex assembly GO:0065003 273 0.029
regulation of rna metabolic process GO:0051252 391 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
Rat
regulation of secretion by cell GO:1903530 208 0.028
metal ion homeostasis GO:0055065 186 0.028
cellular component morphogenesis GO:0032989 155 0.027
Rat
regulation of cell projection organization GO:0031344 175 0.027
calcium ion transport GO:0006816 131 0.027
regulation of hormone levels GO:0010817 187 0.027
apoptotic process GO:0006915 381 0.026
Rat
calcium ion homeostasis GO:0055074 162 0.026
dephosphorylation GO:0016311 98 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
rna biosynthetic process GO:0032774 380 0.026
regulation of signal transduction GO:0009966 318 0.026
Rat
cellular chemical homeostasis GO:0055082 247 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
sensory perception GO:0007600 101 0.026
catabolic process GO:0009056 351 0.026
multicellular organism reproduction GO:0032504 233 0.026
Zebrafish Rat
cell growth GO:0016049 104 0.026
embryonic skeletal system development GO:0048706 3 0.025
protein transport GO:0015031 132 0.025
Rat
eye development GO:0001654 50 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
response to peptide GO:1901652 292 0.025
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
regulation of protein kinase activity GO:0045859 105 0.025
mesonephric tubule development GO:0072164 14 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
regulation of tube size GO:0035150 89 0.025
synaptic transmission GO:0007268 235 0.025
mesoderm development GO:0007498 2 0.025
chemical homeostasis GO:0048878 292 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
protein complex biogenesis GO:0070271 263 0.024
positive regulation of immune system process GO:0002684 90 0.024
cell projection morphogenesis GO:0048858 123 0.024
protein complex subunit organization GO:0071822 302 0.024
intracellular protein transport GO:0006886 79 0.024
Rat
response to oxygen levels GO:0070482 265 0.024
Rat
positive regulation of cell development GO:0010720 176 0.024
cellular component biogenesis GO:0044085 368 0.023
Rat
immune system process GO:0002376 204 0.023
brain development GO:0007420 247 0.023
Rat
negative regulation of protein metabolic process GO:0051248 114 0.023
ureteric bud development GO:0001657 14 0.023
organ morphogenesis GO:0009887 75 0.023
sex differentiation GO:0007548 113 0.022
neuron differentiation GO:0030182 368 0.022
kidney development GO:0001822 67 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
regulation of response to external stimulus GO:0032101 106 0.022
regulation of apoptotic process GO:0042981 335 0.022
Rat
regulation of blood vessel size GO:0050880 89 0.021
positive regulation of locomotion GO:0040017 102 0.021
response to external biotic stimulus GO:0043207 221 0.021
lens development in camera type eye GO:0002088 13 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
anterior posterior pattern specification GO:0009952 1 0.021
reproductive process GO:0022414 372 0.021
Zebrafish Rat
lens fiber cell differentiation GO:0070306 3 0.021
regulation of transporter activity GO:0032409 50 0.020
muscle structure development GO:0061061 87 0.020
Rat
positive regulation of response to external stimulus GO:0032103 51 0.020
aromatic compound catabolic process GO:0019439 168 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of mapk cascade GO:0043408 116 0.019
organophosphate metabolic process GO:0019637 370 0.019
cellular response to stress GO:0033554 269 0.019
Rat
signal release GO:0023061 145 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
amine metabolic process GO:0009308 38 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
proteolysis GO:0006508 175 0.019
negative regulation of gene expression GO:0010629 199 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of ion transmembrane transport GO:0034765 121 0.019
aging GO:0007568 241 0.019
hormone transport GO:0009914 121 0.018
mesoderm morphogenesis GO:0048332 1 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of transcription dna templated GO:0006355 374 0.018
chemotaxis GO:0006935 66 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
response to glucose GO:0009749 136 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
positive regulation of cell motility GO:2000147 97 0.018
regulation of transmembrane transport GO:0034762 122 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
regulation of cell growth GO:0001558 85 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
nucleoside metabolic process GO:0009116 179 0.017
gonad development GO:0008406 104 0.017
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.017
organic substance catabolic process GO:1901575 316 0.017
developmental growth GO:0048589 100 0.017
peristalsis GO:0030432 2 0.017
regulation of locomotion GO:0040012 148 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
phototransduction visible light GO:0007603 2 0.017
kidney epithelium development GO:0072073 19 0.017
regulation of neuron projection development GO:0010975 161 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.017
regulation of cell development GO:0060284 263 0.017
Zebrafish
purine nucleoside metabolic process GO:0042278 169 0.017
organophosphate biosynthetic process GO:0090407 143 0.016
establishment of protein localization GO:0045184 141 0.016
Rat
positive regulation of signal transduction GO:0009967 175 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
salivary gland development GO:0007431 3 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
regulation of intracellular transport GO:0032386 65 0.016
Rat
oxoacid metabolic process GO:0043436 290 0.016
nucleotide metabolic process GO:0009117 279 0.016
head development GO:0060322 247 0.016
Rat
positive regulation of transcription dna templated GO:0045893 197 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
Rat
cellular ketone metabolic process GO:0042180 51 0.015
dicarboxylic acid transport GO:0006835 34 0.015
regulation of cellular localization GO:0060341 263 0.015
Rat
grooming behavior GO:0007625 4 0.015
reproduction GO:0000003 245 0.015
Zebrafish Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to radiation GO:0009314 137 0.015
negative regulation of cell communication GO:0010648 158 0.015
Rat
immune response GO:0006955 104 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
sequestering of calcium ion GO:0051208 8 0.015
lipid biosynthetic process GO:0008610 128 0.015
transcription dna templated GO:0006351 377 0.015
embryonic cranial skeleton morphogenesis GO:0048701 2 0.015
regulation of muscle contraction GO:0006937 53 0.015
cation transport GO:0006812 382 0.015
heterocycle catabolic process GO:0046700 167 0.015
regulation of programmed cell death GO:0043067 341 0.015
Rat
neuron projection morphogenesis GO:0048812 122 0.014
positive regulation of protein modification process GO:0031401 142 0.014
intracellular signal transduction GO:0035556 314 0.014
Rat
positive regulation of cell migration GO:0030335 96 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
action potential GO:0001508 54 0.014
reproductive system development GO:0061458 128 0.014
cell migration GO:0016477 197 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
cardiovascular system development GO:0072358 134 0.014
regulation of hydrolase activity GO:0051336 143 0.014
cellular component assembly GO:0022607 360 0.014
Rat
circulatory system development GO:0072359 134 0.014
epithelial cell differentiation GO:0030855 71 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
mesonephric epithelium development GO:0072163 14 0.014
regulation of blood circulation GO:1903522 110 0.014
response to acid chemical GO:0001101 222 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
sensory perception of bitter taste GO:0050913 4 0.013
blood circulation GO:0008015 183 0.013
cellular catabolic process GO:0044248 295 0.013
regulation of transferase activity GO:0051338 123 0.013
eye morphogenesis GO:0048592 4 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
cellular macromolecule localization GO:0070727 122 0.013
Rat
response to alkaloid GO:0043279 132 0.013
nucleic acid templated transcription GO:0097659 379 0.013
development of primary sexual characteristics GO:0045137 107 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to other organism GO:0051707 220 0.013
regulation of muscle system process GO:0090257 79 0.013
Rat
regulation of vesicle mediated transport GO:0060627 81 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of cell migration GO:0030334 128 0.013
forebrain development GO:0030900 98 0.013
protein processing GO:0016485 68 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of response to stress GO:0080134 126 0.012
Rat
positive regulation of cell communication GO:0010647 271 0.012
reproductive structure development GO:0048608 128 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
tube development GO:0035295 89 0.012
vasoconstriction GO:0042310 54 0.012
positive regulation of biomineral tissue development GO:0070169 4 0.012
multicellular organismal signaling GO:0035637 44 0.012
embryonic skeletal system morphogenesis GO:0048704 3 0.012
localization of cell GO:0051674 202 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
cellular protein localization GO:0034613 122 0.012
Rat
response to wounding GO:0009611 254 0.012
carboxylic acid transport GO:0046942 115 0.012
single organism biosynthetic process GO:0044711 342 0.012
response to anoxia GO:0034059 4 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
response to oxidative stress GO:0006979 186 0.012
Rat
organic acid transport GO:0015849 116 0.012
regulation of secretion GO:0051046 224 0.012
regulation of axonogenesis GO:0050770 37 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
nitrogen compound transport GO:0071705 229 0.011
Rat
multicellular organism growth GO:0035264 1 0.011
protein homooligomerization GO:0051260 91 0.011
gamete generation GO:0007276 124 0.011
Zebrafish
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of immune system process GO:0002682 123 0.011
regulation of behavior GO:0050795 61 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
regulation of body fluid levels GO:0050878 90 0.011
urogenital system development GO:0001655 78 0.011
rho protein signal transduction GO:0007266 11 0.011
axis specification GO:0009798 4 0.011
ion homeostasis GO:0050801 212 0.011
retina morphogenesis in camera type eye GO:0060042 1 0.011
male gonad development GO:0008584 59 0.011
gliogenesis GO:0042063 93 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to estradiol GO:0032355 164 0.011
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
ovulation cycle GO:0042698 67 0.011
Rat
ras protein signal transduction GO:0007265 29 0.011
response to biotic stimulus GO:0009607 226 0.011
purine containing compound metabolic process GO:0072521 253 0.011
multi multicellular organism process GO:0044706 138 0.011
intestinal absorption GO:0050892 3 0.011
inner ear morphogenesis GO:0042472 1 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
developmental induction GO:0031128 2 0.010
motor neuron axon guidance GO:0008045 1 0.010
response to peptide hormone GO:0043434 278 0.010
Rat
negative regulation of transcription dna templated GO:0045892 116 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of amine transport GO:0051954 26 0.010
icosanoid biosynthetic process GO:0046456 18 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
vasculature development GO:0001944 70 0.010
posttranscriptional regulation of gene expression GO:0010608 37 0.010
central nervous system development GO:0007417 311 0.010
Rat
l glutamate import GO:0051938 2 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
mesoderm formation GO:0001707 1 0.010
regulation of kinase activity GO:0043549 117 0.010
response to estrogen GO:0043627 232 0.010
Rat
gastrulation GO:0007369 2 0.010
organophosphate catabolic process GO:0046434 148 0.010
endocytosis GO:0006897 84 0.010
circadian rhythm GO:0007623 88 0.010
regulation of membrane potential GO:0042391 110 0.010

Bmp15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.119
sensory system disease DOID:0050155 0 0.119
disease of anatomical entity DOID:7 0 0.119
Human
eye and adnexa disease DOID:1492 0 0.119
nervous system disease DOID:863 0 0.119
eye disease DOID:5614 0 0.119
retinal degeneration DOID:8466 0 0.041
vascular disease DOID:178 0 0.018
cardiovascular system disease DOID:1287 0 0.018
retinitis pigmentosa DOID:10584 0 0.017
cone rod dystrophy DOID:0050572 0 0.016
hypertension DOID:10763 0 0.013
artery disease DOID:0050828 0 0.013