Rattus norvegicus

0 known processes

Mid2

midline 2

(Aliases: RGD1565674)

Mid2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.051
Human
regulation of phosphate metabolic process GO:0019220 349 0.049
organic acid metabolic process GO:0006082 292 0.044
oxoacid metabolic process GO:0043436 290 0.041
negative regulation of metabolic process GO:0009892 331 0.040
Human
cell projection organization GO:0030030 302 0.038
intracellular signal transduction GO:0035556 314 0.038
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
protein phosphorylation GO:0006468 345 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
central nervous system development GO:0007417 311 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
Human
cellular response to oxygen containing compound GO:1901701 386 0.033
response to extracellular stimulus GO:0009991 380 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
Human
regulation of cellular protein metabolic process GO:0032268 267 0.032
protein complex subunit organization GO:0071822 302 0.032
regulation of rna metabolic process GO:0051252 391 0.032
Human
positive regulation of protein phosphorylation GO:0001934 135 0.032
transcription dna templated GO:0006351 377 0.031
Human
apoptotic process GO:0006915 381 0.031
protein complex biogenesis GO:0070271 263 0.031
response to nutrient levels GO:0031667 370 0.031
transmembrane transport GO:0055085 412 0.030
neuron projection development GO:0031175 273 0.030
regulation of phosphorylation GO:0042325 248 0.029
rna metabolic process GO:0016070 406 0.029
Human
positive regulation of response to stimulus GO:0048584 285 0.028
Human
regulation of cell development GO:0060284 263 0.028
anion transport GO:0006820 178 0.028
regulation of molecular function GO:0065009 398 0.028
Human
negative regulation of cellular metabolic process GO:0031324 281 0.028
Human
negative regulation of gene expression GO:0010629 199 0.028
Human
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of catalytic activity GO:0050790 304 0.027
cellular homeostasis GO:0019725 252 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
macromolecular complex assembly GO:0065003 273 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
regulation of cell differentiation GO:0045595 320 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
multicellular organism reproduction GO:0032504 233 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
protein complex assembly GO:0006461 263 0.025
cellular amine metabolic process GO:0044106 38 0.025
nitrogen compound transport GO:0071705 229 0.025
regulation of nervous system development GO:0051960 264 0.025
cation transport GO:0006812 382 0.025
regulation of apoptotic process GO:0042981 335 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
rna biosynthetic process GO:0032774 380 0.025
Human
nucleic acid templated transcription GO:0097659 379 0.024
Human
response to inorganic substance GO:0010035 377 0.024
amine metabolic process GO:0009308 38 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
Human
cellular ketone metabolic process GO:0042180 51 0.024
positive regulation of biosynthetic process GO:0009891 319 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
Human
regulation of cellular component organization GO:0051128 368 0.023
programmed cell death GO:0012501 392 0.023
cellular component biogenesis GO:0044085 368 0.023
head development GO:0060322 247 0.023
response to metal ion GO:0010038 253 0.023
regulation of hormone levels GO:0010817 187 0.022
response to hypoxia GO:0001666 231 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
positive regulation of nervous system development GO:0051962 178 0.022
single organism reproductive process GO:0044702 297 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
regulation of neuron differentiation GO:0045664 208 0.021
protein localization GO:0008104 191 0.021
Human
tissue development GO:0009888 252 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
neurological system process GO:0050877 219 0.021
homeostatic process GO:0042592 331 0.021
ion transmembrane transport GO:0034220 365 0.021
neuron differentiation GO:0030182 368 0.021
response to wounding GO:0009611 254 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
Human
brain development GO:0007420 247 0.020
choline transport GO:0015871 4 0.020
regulation of programmed cell death GO:0043067 341 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
reactive oxygen species metabolic process GO:0072593 37 0.020
catabolic process GO:0009056 351 0.020
positive regulation of protein modification process GO:0031401 142 0.020
cellular response to stress GO:0033554 269 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
multicellular organismal reproductive process GO:0048609 233 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
regulation of neurogenesis GO:0050767 247 0.019
negative regulation of molecular function GO:0044092 133 0.019
regulation of kinase activity GO:0043549 117 0.019
multi organism reproductive process GO:0044703 262 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
positive regulation of transferase activity GO:0051347 81 0.019
cellular component assembly GO:0022607 360 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
regulation of protein modification process GO:0031399 194 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
reproduction GO:0000003 245 0.018
single organism catabolic process GO:0044712 283 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
regulation of protein metabolic process GO:0051246 289 0.018
positive regulation of developmental process GO:0051094 283 0.018
single organism biosynthetic process GO:0044711 342 0.017
response to acid chemical GO:0001101 222 0.017
cation transmembrane transport GO:0098655 263 0.017
macromolecule localization GO:0033036 252 0.017
Human
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of mapk cascade GO:0043408 116 0.017
purine containing compound metabolic process GO:0072521 253 0.017
regulation of cell proliferation GO:0042127 359 0.017
response to peptide GO:1901652 292 0.017
organophosphate metabolic process GO:0019637 370 0.017
reproductive process GO:0022414 372 0.017
regulation of transferase activity GO:0051338 123 0.017
positive regulation of gene expression GO:0010628 244 0.016
circulatory system process GO:0003013 183 0.016
organic substance catabolic process GO:1901575 316 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
response to decreased oxygen levels GO:0036293 237 0.016
nucleotide metabolic process GO:0009117 279 0.016
response to oxidative stress GO:0006979 186 0.016
cellular catabolic process GO:0044248 295 0.016
negative regulation of cell communication GO:0010648 158 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
protein oligomerization GO:0051259 191 0.015
blood circulation GO:0008015 183 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
positive regulation of cell death GO:0010942 184 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
response to nutrient GO:0007584 248 0.015
growth GO:0040007 165 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
Human
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
proteolysis GO:0006508 175 0.015
regulation of cell projection organization GO:0031344 175 0.015
aging GO:0007568 241 0.015
response to peptide hormone GO:0043434 278 0.015
action potential GO:0001508 54 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
regulation of cellular localization GO:0060341 263 0.015
positive regulation of molecular function GO:0044093 230 0.015
Human
neuron development GO:0048666 286 0.015
cell type specific apoptotic process GO:0097285 134 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.014
positive regulation of cell development GO:0010720 176 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
response to glucocorticoid GO:0051384 223 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
regulation of neuron projection development GO:0010975 161 0.014
peptidyl amino acid modification GO:0018193 126 0.014
response to ethanol GO:0045471 162 0.014
cellular macromolecule localization GO:0070727 122 0.014
Human
cellular chemical homeostasis GO:0055082 247 0.014
chemical homeostasis GO:0048878 292 0.014
cellular component movement GO:0006928 248 0.014
response to external biotic stimulus GO:0043207 221 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
Human
cellular protein localization GO:0034613 122 0.014
Human
monovalent inorganic cation transport GO:0015672 172 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
axis specification GO:0009798 4 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
cellular response to external stimulus GO:0071496 118 0.014
single organism intracellular transport GO:1902582 166 0.014
organic anion transport GO:0015711 132 0.014
response to bacterium GO:0009617 200 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
Human
regulation of protein kinase activity GO:0045859 105 0.013
single organism organelle organization GO:1902589 180 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
lipid metabolic process GO:0006629 283 0.013
negative regulation of cell death GO:0060548 229 0.013
organelle organization GO:0006996 266 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
response to corticosteroid GO:0031960 235 0.013
positive regulation of signaling GO:0023056 270 0.013
Human
cellular response to alcohol GO:0097306 87 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to ketone GO:1901654 182 0.013
regulation of anatomical structure size GO:0090066 135 0.013
cell part morphogenesis GO:0032990 123 0.012
metal ion transport GO:0030001 289 0.012
cellular response to peptide GO:1901653 133 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
secretion GO:0046903 307 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
response to growth factor GO:0070848 189 0.012
eye morphogenesis GO:0048592 4 0.012
regulation of signal transduction GO:0009966 318 0.012
Human
response to estrogen GO:0043627 232 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
positive regulation of cell communication GO:0010647 271 0.012
Human
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of developmental process GO:0051093 125 0.012
chromosome segregation GO:0007059 2 0.012
purine containing compound catabolic process GO:0072523 138 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
cellular cation homeostasis GO:0030003 180 0.012
positive regulation of signal transduction GO:0009967 175 0.012
Human
heart morphogenesis GO:0003007 3 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of transcription dna templated GO:0045892 116 0.011
cellular response to lipid GO:0071396 201 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of membrane potential GO:0042391 110 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
cellular component morphogenesis GO:0032989 155 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
cell projection morphogenesis GO:0048858 123 0.011
lipid storage GO:0019915 1 0.011
regulation of blood vessel size GO:0050880 89 0.011
cardiovascular system development GO:0072358 134 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
Human
organic hydroxy compound metabolic process GO:1901615 115 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
mapk cascade GO:0000165 140 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
response to alkaloid GO:0043279 132 0.011
locomotion GO:0040011 237 0.011
Human
sensory organ development GO:0007423 74 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
salivary gland development GO:0007431 3 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
glial cell differentiation GO:0010001 65 0.011
carboxylic acid transport GO:0046942 115 0.011
actin filament based process GO:0030029 86 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
behavior GO:0007610 205 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regeneration GO:0031099 163 0.011
positive regulation of kinase activity GO:0033674 77 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
cytoplasmic transport GO:0016482 115 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
response to reactive oxygen species GO:0000302 120 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
Human
response to camp GO:0051591 91 0.010
metal ion homeostasis GO:0055065 186 0.010
motor neuron axon guidance GO:0008045 1 0.010
intracellular transport GO:0046907 185 0.010
regulation of system process GO:0044057 208 0.010
neuronal action potential GO:0019228 35 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
protein transport GO:0015031 132 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
sexual reproduction GO:0019953 148 0.010

Mid2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
sensory system disease DOID:0050155 0 0.016
eye disease DOID:5614 0 0.010
eye and adnexa disease DOID:1492 0 0.010