Rattus norvegicus

0 known processes

Dctn1

dynactin 1

Dctn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.555
response to nutrient GO:0007584 248 0.365
transcription from rna polymerase ii promoter GO:0006366 252 0.323
regulation of rna metabolic process GO:0051252 391 0.222
lipid metabolic process GO:0006629 283 0.202
single organism cellular localization GO:1902580 102 0.183
Fly
cell projection organization GO:0030030 302 0.148
negative regulation of metabolic process GO:0009892 331 0.144
cellular lipid metabolic process GO:0044255 208 0.111
single organism organelle organization GO:1902589 180 0.109
Fly
negative regulation of cellular component organization GO:0051129 83 0.103
growth GO:0040007 165 0.102
rna metabolic process GO:0016070 406 0.097
transcription dna templated GO:0006351 377 0.092
protein localization to membrane GO:0072657 36 0.085
regulation of nervous system development GO:0051960 264 0.084
negative regulation of cellular metabolic process GO:0031324 281 0.083
insulin like growth factor receptor signaling pathway GO:0048009 3 0.083
protein localization GO:0008104 191 0.080
Fly
regulation of rna biosynthetic process GO:2001141 381 0.075
tubulin deacetylation GO:0090042 1 0.074
response to extracellular stimulus GO:0009991 380 0.074
cellular response to hormone stimulus GO:0032870 247 0.071
protein import GO:0017038 37 0.069
response to peptide GO:1901652 292 0.068
multi multicellular organism process GO:0044706 138 0.066
neuron neuron synaptic transmission GO:0007270 60 0.066
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.066
macromolecular complex subunit organization GO:0043933 339 0.063
Fly
response to estradiol GO:0032355 164 0.062
membrane organization GO:0061024 94 0.062
regulation of nucleic acid templated transcription GO:1903506 380 0.059
single organism membrane organization GO:0044802 74 0.059
cellular amino acid metabolic process GO:0006520 107 0.058
negative regulation of cellular protein metabolic process GO:0032269 106 0.057
programmed cell death GO:0012501 392 0.055
response to decreased oxygen levels GO:0036293 237 0.055
response to nutrient levels GO:0031667 370 0.053
central nervous system development GO:0007417 311 0.053
negative regulation of nervous system development GO:0051961 79 0.053
rna biosynthetic process GO:0032774 380 0.052
nucleic acid templated transcription GO:0097659 379 0.052
neuron differentiation GO:0030182 368 0.051
Fly
negative regulation of cell proliferation GO:0008285 119 0.051
regulation of cell development GO:0060284 263 0.051
single organism intracellular transport GO:1902582 166 0.050
Fly
positive regulation of cell death GO:0010942 184 0.049
guanosine containing compound catabolic process GO:1901069 71 0.049
neuron development GO:0048666 286 0.047
Fly
synaptic transmission GO:0007268 235 0.047
Fly
spindle organization GO:0007051 2 0.047
Fly
synaptic growth at neuromuscular junction GO:0051124 1 0.046
intracellular transport GO:0046907 185 0.046
Fly
reproductive process GO:0022414 372 0.046
response to peptide hormone GO:0043434 278 0.045
negative regulation of signaling GO:0023057 157 0.044
regulation of transcription dna templated GO:0006355 374 0.043
cellular ketone metabolic process GO:0042180 51 0.043
cellular response to oxygen containing compound GO:1901701 386 0.042
negative regulation of biosynthetic process GO:0009890 168 0.042
multi organism reproductive process GO:0044703 262 0.042
amide biosynthetic process GO:0043604 10 0.042
mitotic spindle organization GO:0007052 2 0.041
Fly
positive regulation of cell differentiation GO:0045597 217 0.041
lipid biosynthetic process GO:0008610 128 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.040
response to oxygen levels GO:0070482 265 0.040
cellular protein localization GO:0034613 122 0.039
Fly
macromolecule localization GO:0033036 252 0.038
Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
neuron projection development GO:0031175 273 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
positive regulation of apoptotic process GO:0043065 154 0.038
female pregnancy GO:0007565 122 0.037
positive regulation of molecular function GO:0044093 230 0.036
regulation of cellular component organization GO:0051128 368 0.036
cellular response to nitrogen compound GO:1901699 210 0.035
negative regulation of cell communication GO:0010648 158 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
cellular chemical homeostasis GO:0055082 247 0.035
regulation of apoptotic process GO:0042981 335 0.035
protein heterooligomerization GO:0051291 89 0.035
cellular macromolecule localization GO:0070727 122 0.035
Fly
blood circulation GO:0008015 183 0.033
reproduction GO:0000003 245 0.033
cellular amine metabolic process GO:0044106 38 0.033
apoptotic process GO:0006915 381 0.033
multicellular organism reproduction GO:0032504 233 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.032
positive regulation of gene expression GO:0010628 244 0.032
ras protein signal transduction GO:0007265 29 0.032
glycerolipid metabolic process GO:0046486 67 0.032
protein import into nucleus GO:0006606 35 0.032
protein phosphorylation GO:0006468 345 0.032
cellular component biogenesis GO:0044085 368 0.031
Fly
response to insulin GO:0032868 133 0.031
phospholipid biosynthetic process GO:0008654 29 0.031
organophosphate biosynthetic process GO:0090407 143 0.031
amine metabolic process GO:0009308 38 0.031
positive regulation of growth GO:0045927 55 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
organelle organization GO:0006996 266 0.030
Fly
negative regulation of protein metabolic process GO:0051248 114 0.030
cellular response to stress GO:0033554 269 0.030
negative regulation of gene expression GO:0010629 199 0.029
tube formation GO:0035148 3 0.029
oxoacid metabolic process GO:0043436 290 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
endomembrane system organization GO:0010256 48 0.029
regulation of blood circulation GO:1903522 110 0.028
regulation of cell cycle GO:0051726 73 0.028
response to estrogen GO:0043627 232 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
chemical homeostasis GO:0048878 292 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.028
cellular response to organonitrogen compound GO:0071417 197 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
eye morphogenesis GO:0048592 4 0.027
Fly
single organism nuclear import GO:1902593 35 0.027
single organism biosynthetic process GO:0044711 342 0.026
cell cell signaling GO:0007267 335 0.026
Fly
cellular catabolic process GO:0044248 295 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
hormone transport GO:0009914 121 0.025
morphogenesis of embryonic epithelium GO:0016331 3 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
cation homeostasis GO:0055080 195 0.025
regulation of anatomical structure size GO:0090066 135 0.025
response to hexose GO:0009746 144 0.024
catabolic process GO:0009056 351 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
urinary tract smooth muscle contraction GO:0014848 4 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
regulation of cell growth GO:0001558 85 0.024
urinary bladder smooth muscle contraction GO:0014832 4 0.023
nuclear transport GO:0051169 49 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
cellular cation homeostasis GO:0030003 180 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
protein complex biogenesis GO:0070271 263 0.022
Fly
regulation of gtpase activity GO:0043087 57 0.022
regulation of growth GO:0040008 105 0.022
homeostatic process GO:0042592 331 0.022
rna localization GO:0006403 4 0.022
Fly
epithelial tube formation GO:0072175 3 0.022
anterior posterior pattern specification GO:0009952 1 0.022
response to ketone GO:1901654 182 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
neuron projection morphogenesis GO:0048812 122 0.021
intracellular signal transduction GO:0035556 314 0.021
regulation of protein modification process GO:0031399 194 0.021
response to monosaccharide GO:0034284 159 0.021
regulation of neurogenesis GO:0050767 247 0.021
regulation of nucleotide catabolic process GO:0030811 65 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of catabolic process GO:0009894 113 0.020
behavior GO:0007610 205 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
regulation of protein metabolic process GO:0051246 289 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
cellular homeostasis GO:0019725 252 0.020
cell projection morphogenesis GO:0048858 123 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
secretion by cell GO:0032940 248 0.019
response to hypoxia GO:0001666 231 0.019
regulation of signal transduction GO:0009966 318 0.019
regulation of tube size GO:0035150 89 0.019
positive regulation of gtp catabolic process GO:0033126 48 0.019
small gtpase mediated signal transduction GO:0007264 36 0.018
regulation of protein localization GO:0032880 81 0.018
regulation of secretion GO:0051046 224 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
peptide biosynthetic process GO:0043043 3 0.018
immune effector process GO:0002252 53 0.018
Fly
male mating behavior GO:0060179 3 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of system process GO:0044057 208 0.018
positive regulation of hydrolase activity GO:0051345 86 0.017
peptide secretion GO:0002790 86 0.017
signal release GO:0023061 145 0.017
phospholipid metabolic process GO:0006644 61 0.017
protein complex subunit organization GO:0071822 302 0.017
Fly
single organism reproductive process GO:0044702 297 0.017
intracellular protein transport GO:0006886 79 0.017
Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.017
synaptic transmission gabaergic GO:0051932 22 0.017
cardiovascular system development GO:0072358 134 0.017
response to other organism GO:0051707 220 0.017
response to carbohydrate GO:0009743 183 0.017
brain development GO:0007420 247 0.017
multicellular organismal reproductive process GO:0048609 233 0.016
learning or memory GO:0007611 90 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular component assembly GO:0022607 360 0.016
Fly
response to glucose GO:0009749 136 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
multicellular organismal signaling GO:0035637 44 0.016
cellular response to external stimulus GO:0071496 118 0.016
regulation of catalytic activity GO:0050790 304 0.016
positive regulation of developmental process GO:0051094 283 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
macromolecular complex assembly GO:0065003 273 0.016
Fly
limb morphogenesis GO:0035108 4 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
protein targeting to nucleus GO:0044744 35 0.016
epithelium development GO:0060429 96 0.016
Fly
regulation of protein transport GO:0051223 68 0.016
regulation of hydrolase activity GO:0051336 143 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
cell growth GO:0016049 104 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
negative regulation of epithelial cell proliferation GO:0050680 16 0.015
regulation of molecular function GO:0065009 398 0.015
gtp catabolic process GO:0006184 71 0.015
purine containing compound metabolic process GO:0072521 253 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of cell development GO:0010720 176 0.015
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of protein modification process GO:0031400 52 0.014
gtp metabolic process GO:0046039 72 0.014
cytoplasmic transport GO:0016482 115 0.014
circulatory system process GO:0003013 183 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
ion homeostasis GO:0050801 212 0.014
inflammatory response GO:0006954 150 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
response to acid chemical GO:0001101 222 0.014
head development GO:0060322 247 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of rab gtpase activity GO:0032313 3 0.014
cellular ion homeostasis GO:0006873 184 0.014
glycerophospholipid metabolic process GO:0006650 47 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
rab protein signal transduction GO:0032482 1 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
aging GO:0007568 241 0.013
peptide transport GO:0015833 97 0.013
necroptotic process GO:0070266 2 0.013
protein transport GO:0015031 132 0.013
Fly
covalent chromatin modification GO:0016569 30 0.013
regulation of hormone secretion GO:0046883 106 0.013
chromatin organization GO:0006325 34 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
multicellular organism growth GO:0035264 1 0.013
peptide hormone secretion GO:0030072 84 0.013
cognition GO:0050890 92 0.013
nucleotide metabolic process GO:0009117 279 0.013
nucleoside catabolic process GO:0009164 126 0.013
liver development GO:0001889 90 0.013
acute phase response GO:0006953 20 0.013
regulation of axonogenesis GO:0050770 37 0.013
regulation of neuron projection development GO:0010975 161 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
negative regulation of transport GO:0051051 136 0.013
response to toxic substance GO:0009636 133 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
gliogenesis GO:0042063 93 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
organophosphate metabolic process GO:0019637 370 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of insulin secretion GO:0050796 65 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
developmental growth GO:0048589 100 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
negative regulation of organ growth GO:0046621 3 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
vesicle mediated transport GO:0016192 181 0.012
Fly
cellular response to peptide GO:1901653 133 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
jak stat cascade GO:0007259 26 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of organ growth GO:0046620 13 0.012
regulation of cell projection organization GO:0031344 175 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
positive regulation of nervous system development GO:0051962 178 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
nitrogen compound transport GO:0071705 229 0.012
Fly
monosaccharide transport GO:0015749 31 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
negative regulation of developmental process GO:0051093 125 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
double strand break repair GO:0006302 1 0.012
regulation of intracellular protein transport GO:0033157 34 0.012
protein oligomerization GO:0051259 191 0.012
negative regulation of cell death GO:0060548 229 0.012
response to external biotic stimulus GO:0043207 221 0.011
regulation of developmental growth GO:0048638 45 0.011
autophagic cell death GO:0048102 4 0.011
axonogenesis GO:0007409 71 0.011
salivary gland development GO:0007431 3 0.011
plasma membrane organization GO:0007009 17 0.011
cellular response to hypoxia GO:0071456 51 0.011
regulation of phosphorylation GO:0042325 248 0.011
protein localization to nucleus GO:0034504 39 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
organic substance catabolic process GO:1901575 316 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
learning GO:0007612 33 0.011
autophagy GO:0006914 19 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
regulation of blood vessel endothelial cell migration GO:0043535 4 0.011
hormone secretion GO:0046879 115 0.011
transmembrane transport GO:0055085 412 0.011
peptidyl amino acid modification GO:0018193 126 0.011
gastrulation GO:0007369 2 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
neural tube formation GO:0001841 1 0.011
ovulation cycle GO:0042698 67 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
regulation of response to external stimulus GO:0032101 106 0.011
glial cell differentiation GO:0010001 65 0.011
insulin receptor signaling pathway GO:0008286 24 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
mrna metabolic process GO:0016071 20 0.011
regulation of body fluid levels GO:0050878 90 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
axis specification GO:0009798 4 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
nuclear import GO:0051170 35 0.010
regulation of hormone levels GO:0010817 187 0.010
response to progesterone GO:0032570 48 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
response to vitamin GO:0033273 131 0.010
developmental growth involved in morphogenesis GO:0060560 33 0.010
embryonic epithelial tube formation GO:0001838 3 0.010
amide transport GO:0042886 105 0.010
cellular response to oxygen levels GO:0071453 60 0.010
appendage morphogenesis GO:0035107 4 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
regulation of blood pressure GO:0008217 83 0.010
regulation of programmed cell death GO:0043067 341 0.010
negative regulation of signal transduction GO:0009968 83 0.010
dendrite morphogenesis GO:0048813 43 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
axon development GO:0061564 96 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
embryonic skeletal system development GO:0048706 3 0.010
regulation of intracellular transport GO:0032386 65 0.010
small molecule biosynthetic process GO:0044283 124 0.010
positive regulation of gtpase activity GO:0043547 47 0.010
response to growth factor GO:0070848 189 0.010
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
gamete generation GO:0007276 124 0.010
nucleic acid transport GO:0050657 3 0.010
Fly

Dctn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
parkinson s disease DOID:14330 0 0.360
synucleinopathy DOID:0050890 0 0.360
central nervous system disease DOID:331 0 0.360
disease of anatomical entity DOID:7 0 0.360
neurodegenerative disease DOID:1289 0 0.360
nervous system disease DOID:863 0 0.360
neuromuscular disease DOID:440 0 0.041
charcot marie tooth disease type 2 DOID:0050539 0 0.041
charcot marie tooth disease DOID:10595 0 0.041
neuropathy DOID:870 0 0.041
brain disease DOID:936 0 0.021
epilepsy syndrome DOID:1826 0 0.018
electroclinical syndrome DOID:0050701 0 0.018
cardiovascular system disease DOID:1287 0 0.015
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011