|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.399
|
Fly |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.368
|
Fly |
|
|
response to molecule of fungal origin
|
GO:0002238 |
3 |
0.336
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
81 |
0.330
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.303
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.300
|
Human Mouse |
|
|
cation transport
|
GO:0006812 |
382 |
0.292
|
Mouse |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.260
|
Human Mouse |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.245
|
Human Mouse |
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.245
|
Mouse Fly |
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
10 |
0.244
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.239
|
Fly |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.239
|
Fly |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
24 |
0.225
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.223
|
Fly |
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.219
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.216
|
Mouse |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.213
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.212
|
Fly |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.207
|
Human Mouse |
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.206
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.204
|
Fly |
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.204
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.195
|
Human Mouse |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.190
|
|
|
|
positive regulation of fc receptor mediated stimulatory signaling pathway
|
GO:0060369 |
1 |
0.187
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.183
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.179
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.176
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.169
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.162
|
Human Mouse |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.158
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.155
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.154
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.144
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.143
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.143
|
Mouse |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
5 |
0.139
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.138
|
Human Mouse |
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.137
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.134
|
Mouse |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.132
|
Mouse |
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.131
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.130
|
Fly |
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.129
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
19 |
0.128
|
Mouse |
|
|
erbb signaling pathway
|
GO:0038127 |
23 |
0.125
|
Fly |
|
|
organelle organization
|
GO:0006996 |
266 |
0.125
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.125
|
Human Mouse |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.124
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.123
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.122
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.122
|
Mouse |
|
|
regulation of fc receptor mediated stimulatory signaling pathway
|
GO:0060368 |
3 |
0.121
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.119
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.118
|
Human Mouse |
|
|
immune system process
|
GO:0002376 |
204 |
0.116
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
220 |
0.116
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.115
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.113
|
Fly |
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.113
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.113
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.111
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.110
|
Mouse |
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.108
|
Human Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.107
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
49 |
0.106
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.106
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.106
|
Fly |
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.105
|
Human Mouse |
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.104
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.103
|
Human Mouse |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.103
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
29 |
0.102
|
Mouse |
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
2 |
0.102
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.101
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.100
|
Mouse |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.098
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.097
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.097
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
19 |
0.096
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.096
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.094
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.094
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
3 |
0.094
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.092
|
Human Mouse |
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.091
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.091
|
Human Mouse Fly |
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.090
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.090
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.089
|
Human Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.087
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.087
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
25 |
0.087
|
Mouse |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.087
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.087
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.087
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
1 |
0.087
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.086
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.086
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.085
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.085
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
118 |
0.085
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.084
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.084
|
Human Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.084
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.083
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.083
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
36 |
0.082
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.082
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
33 |
0.081
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.080
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.079
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.079
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.078
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.078
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.077
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.077
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.077
|
|
|
|
histamine secretion involved in inflammatory response
|
GO:0002441 |
3 |
0.077
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.077
|
Human Mouse Rat Fly |
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.076
|
Mouse |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.076
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.076
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
152 |
0.076
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
47 |
0.075
|
Mouse |
|
|
establishment of organelle localization
|
GO:0051656 |
37 |
0.074
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.072
|
Mouse |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.072
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.071
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.070
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
19 |
0.070
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.070
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.070
|
Human Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.069
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.069
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.069
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.069
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.068
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.068
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.068
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.068
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.067
|
Mouse |
|
|
neuron death
|
GO:0070997 |
127 |
0.067
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.067
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.067
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.066
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.066
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.066
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.065
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.065
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.065
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.065
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.064
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
2 |
0.064
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
10 |
0.064
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.064
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.064
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.063
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.063
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.063
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
72 |
0.063
|
Human Mouse |
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
2 |
0.063
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
292 |
0.062
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.062
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.061
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.060
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.060
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.060
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.060
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
16 |
0.059
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.059
|
|
|
|
response to insulin
|
GO:0032868 |
133 |
0.059
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
4 |
0.059
|
Mouse |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.059
|
Human Mouse |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.059
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.058
|
Mouse |
|
|
dna metabolic process
|
GO:0006259 |
96 |
0.058
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.058
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.058
|
|
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.058
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
55 |
0.058
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.058
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.057
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.057
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.057
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
26 |
0.057
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.057
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.057
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
44 |
0.057
|
Human Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
4 |
0.057
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
2 |
0.057
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.056
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.056
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.055
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.055
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.055
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.055
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
47 |
0.054
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.054
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.054
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.054
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.053
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.052
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.052
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.052
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.052
|
|
|
|
exocytosis
|
GO:0006887 |
60 |
0.052
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.052
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.052
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
69 |
0.051
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.051
|
Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.051
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.051
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.051
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.051
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
72 |
0.051
|
|
|
|
negative regulation of arp2 3 complex mediated actin nucleation
|
GO:0034316 |
1 |
0.050
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.050
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
3 |
0.050
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.049
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.049
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.049
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.049
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.049
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
1 |
0.049
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.049
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
39 |
0.049
|
Mouse |
|
|
central nervous system development
|
GO:0007417 |
311 |
0.048
|
Fly |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.048
|
Mouse Fly |
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.048
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.048
|
Mouse |
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.048
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.048
|
Fly |
|
|
olfactory learning
|
GO:0008355 |
1 |
0.048
|
|
|
|
organelle localization
|
GO:0051640 |
55 |
0.048
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.048
|
Fly |
|
|
response to bacterium
|
GO:0009617 |
200 |
0.047
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.047
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.047
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.046
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.046
|
Human |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.046
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.046
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
3 |
0.045
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
26 |
0.045
|
Mouse |
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.045
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.044
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.044
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.044
|
Human Mouse |
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.044
|
Fly |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.044
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.044
|
|
|
|
actin filament organization
|
GO:0007015 |
42 |
0.044
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.044
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.043
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.043
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.043
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.043
|
|
|
|
hexose metabolic process
|
GO:0019318 |
58 |
0.043
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.042
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.042
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
1 |
0.042
|
Mouse |
|
|
brain development
|
GO:0007420 |
247 |
0.042
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
48 |
0.042
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.042
|
Fly |
|
|
olfactory behavior
|
GO:0042048 |
2 |
0.042
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
39 |
0.041
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.041
|
Mouse |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.041
|
Human Mouse |
|
|
salivary gland development
|
GO:0007431 |
3 |
0.040
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.040
|
Fly |
|
|
neurological system process
|
GO:0050877 |
219 |
0.040
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
29 |
0.040
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.040
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.040
|
Fly |
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.040
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.039
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
22 |
0.039
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.039
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
26 |
0.039
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.039
|
|
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.038
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.038
|
|
|
|
immune effector process
|
GO:0002252 |
53 |
0.038
|
Mouse |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.038
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.038
|
Human Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.038
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.038
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.038
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
5 |
0.038
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.038
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.037
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.037
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.037
|
Mouse |
|
|
tissue development
|
GO:0009888 |
252 |
0.037
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.037
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.037
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.037
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.036
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
3 |
0.036
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
18 |
0.036
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
130 |
0.036
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.036
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.035
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.035
|
|
|
|
positive regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010641 |
1 |
0.035
|
|
|
|
axonogenesis
|
GO:0007409 |
71 |
0.035
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.035
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.035
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.035
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.035
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
65 |
0.035
|
Mouse |
|
|
secretion by cell
|
GO:0032940 |
248 |
0.035
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
7 |
0.035
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.035
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.034
|
|
|
|
response to ph
|
GO:0009268 |
27 |
0.034
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.034
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.034
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
7 |
0.034
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
3 |
0.034
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.034
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.034
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.034
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
29 |
0.034
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.033
|
|
|
|
muscle cell migration
|
GO:0014812 |
36 |
0.033
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.033
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.033
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.033
|
Mouse |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
38 |
0.033
|
Mouse |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.033
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.033
|
Mouse |
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
25 |
0.033
|
Mouse |
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.032
|
Fly |
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.032
|
Mouse |
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.032
|
|
|
|
growth
|
GO:0040007 |
165 |
0.032
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.032
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.032
|
Mouse |
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.032
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.032
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
1 |
0.032
|
Mouse |
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.032
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
2 |
0.032
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.031
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.031
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.031
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.031
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.031
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.031
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.031
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.031
|
Fly |
|
|
b cell differentiation
|
GO:0030183 |
2 |
0.031
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
5 |
0.031
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.031
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
12 |
0.030
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.030
|
Fly |
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
25 |
0.030
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
83 |
0.030
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.030
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.030
|
Human Mouse |
|
|
glucose metabolic process
|
GO:0006006 |
52 |
0.030
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
2 |
0.030
|
|
|
|
regulation of immune response
|
GO:0050776 |
55 |
0.030
|
Mouse |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.029
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.029
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.029
|
|
|
|
response to fatty acid
|
GO:0070542 |
65 |
0.029
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.029
|
Mouse |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
41 |
0.028
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.028
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.028
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.028
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.028
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
20 |
0.028
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.028
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.028
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
14 |
0.028
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
10 |
0.028
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.027
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
46 |
0.027
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.027
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
52 |
0.027
|
Human Mouse |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
39 |
0.027
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
44 |
0.027
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
30 |
0.027
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
1 |
0.027
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
26 |
0.027
|
Mouse |
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.027
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
51 |
0.027
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.027
|
|
|
|
biological adhesion
|
GO:0022610 |
110 |
0.027
|
Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.026
|
Mouse |
|
|
neuron development
|
GO:0048666 |
286 |
0.026
|
Fly |
|
|
axis specification
|
GO:0009798 |
4 |
0.026
|
Fly |
|
|
lysosome localization
|
GO:0032418 |
10 |
0.026
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
2 |
0.026
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
26 |
0.026
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
2 |
0.026
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
61 |
0.025
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.025
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
11 |
0.025
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.025
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.025
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.025
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.025
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
16 |
0.025
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.024
|
Fly |
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.024
|
|
|
|
head development
|
GO:0060322 |
247 |
0.024
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.024
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.024
|
|
|
|
cell cycle process
|
GO:0022402 |
57 |
0.024
|
Human |
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
2 |
0.024
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
2 |
0.024
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
35 |
0.024
|
Fly |
|
|
cell cell junction organization
|
GO:0045216 |
20 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.023
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.023
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
55 |
0.023
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
2 |
0.023
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.023
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.023
|
|
|
|
t cell proliferation
|
GO:0042098 |
19 |
0.023
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
115 |
0.023
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.022
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.022
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
55 |
0.022
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.022
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.022
|
Fly |
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
2 |
0.022
|
Mouse |
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.022
|
Mouse |
|
|
aging
|
GO:0007568 |
241 |
0.022
|
|
|
|
activation of protein kinase b activity
|
GO:0032148 |
3 |
0.022
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.022
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.022
|
Mouse Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.022
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.022
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
13 |
0.022
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.021
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
61 |
0.021
|
|
|
|
skeletal system development
|
GO:0001501 |
41 |
0.021
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
19 |
0.021
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
35 |
0.021
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.021
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.021
|
Fly |
|
|
response to axon injury
|
GO:0048678 |
59 |
0.021
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
68 |
0.021
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
14 |
0.020
|
Human |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
48 |
0.020
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.020
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.020
|
Human Mouse |
|
|
protein polymerization
|
GO:0051258 |
22 |
0.020
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
1 |
0.020
|
|
|
|
activation of immune response
|
GO:0002253 |
26 |
0.020
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.020
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
16 |
0.020
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.020
|
|
|
|
mast cell degranulation
|
GO:0043303 |
10 |
0.020
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
49 |
0.020
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.020
|
Human Mouse |
|
|
localization of cell
|
GO:0051674 |
202 |
0.020
|
Fly |
|
|
lymphocyte homeostasis
|
GO:0002260 |
2 |
0.020
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.020
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
12 |
0.019
|
|
|
|
learning
|
GO:0007612 |
33 |
0.019
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
3 |
0.019
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.019
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.019
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
33 |
0.019
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
83 |
0.019
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.019
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.019
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
29 |
0.019
|
Mouse |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
56 |
0.019
|
|
|
|
response to amino acid
|
GO:0043200 |
75 |
0.019
|
|
|
|
regulation of cellular extravasation
|
GO:0002691 |
2 |
0.019
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.018
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
34 |
0.018
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.018
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.018
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
48 |
0.018
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
72 |
0.018
|
Human Mouse |
|
|
regeneration
|
GO:0031099 |
163 |
0.018
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.018
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
29 |
0.018
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
13 |
0.018
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
2 |
0.018
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.018
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
1 |
0.018
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
4 |
0.018
|
|
