Rattus norvegicus

0 known processes

Neu3

sialidase 3 (membrane sialidase)

Neu3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cardiac conduction GO:0061337 2 0.107
anion transport GO:0006820 178 0.104
cation homeostasis GO:0055080 195 0.104
renal system development GO:0072001 67 0.094
cation transport GO:0006812 382 0.091
regulation of cellular localization GO:0060341 263 0.084
regulation of metal ion transport GO:0010959 118 0.082
cellular component assembly GO:0022607 360 0.079
cellular response to endogenous stimulus GO:0071495 377 0.075
regulation of ion transport GO:0043269 245 0.064
cellular chemical homeostasis GO:0055082 247 0.056
cellular cation homeostasis GO:0030003 180 0.054
rna metabolic process GO:0016070 406 0.054
cellular divalent inorganic cation homeostasis GO:0072503 162 0.054
carbohydrate derivative metabolic process GO:1901135 346 0.053
membrane repolarization GO:0086009 1 0.053
locomotion GO:0040011 237 0.053
neuron development GO:0048666 286 0.050
regulation of transcription dna templated GO:0006355 374 0.050
defense response GO:0006952 194 0.049
ion homeostasis GO:0050801 212 0.048
cellular response to nitrogen compound GO:1901699 210 0.047
positive regulation of nucleic acid templated transcription GO:1903508 197 0.047
nucleic acid templated transcription GO:0097659 379 0.047
acute inflammatory response GO:0002526 58 0.046
regulation of cell differentiation GO:0045595 320 0.046
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
regulation of intracellular signal transduction GO:1902531 218 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.045
amide transport GO:0042886 105 0.045
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
transcription dna templated GO:0006351 377 0.044
positive regulation of cell proliferation GO:0008284 249 0.042
inflammatory response GO:0006954 150 0.042
hormone secretion GO:0046879 115 0.042
kidney development GO:0001822 67 0.042
blood circulation GO:0008015 183 0.042
regulation of system process GO:0044057 208 0.040
positive regulation of biosynthetic process GO:0009891 319 0.040
positive regulation of rna metabolic process GO:0051254 203 0.039
protein complex biogenesis GO:0070271 263 0.039
intracellular transport GO:0046907 185 0.039
positive regulation of immune system process GO:0002684 90 0.039
regulation of homeostatic process GO:0032844 101 0.038
catabolic process GO:0009056 351 0.038
secretion by cell GO:0032940 248 0.038
regulation of membrane repolarization GO:0060306 1 0.037
positive regulation of rna biosynthetic process GO:1902680 197 0.037
cardiac chamber development GO:0003205 1 0.037
cellular amine metabolic process GO:0044106 38 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
intracellular signal transduction GO:0035556 314 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
cellular metal ion homeostasis GO:0006875 172 0.034
potassium ion transmembrane transport GO:0071805 71 0.034
amine metabolic process GO:0009308 38 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
regulation of calcium ion transport GO:0051924 77 0.033
neuron projection development GO:0031175 273 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
homeostatic process GO:0042592 331 0.033
calcium ion homeostasis GO:0055074 162 0.033
reproductive process GO:0022414 372 0.032
organelle organization GO:0006996 266 0.032
heart contraction GO:0060047 57 0.032
transmembrane transport GO:0055085 412 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
regulation of cell proliferation GO:0042127 359 0.031
cellular homeostasis GO:0019725 252 0.030
actin filament based process GO:0030029 86 0.030
urogenital system development GO:0001655 78 0.030
immune system process GO:0002376 204 0.030
regulation of vesicle mediated transport GO:0060627 81 0.029
negative regulation of secretion GO:0051048 82 0.029
organic acid metabolic process GO:0006082 292 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
positive regulation of transport GO:0051050 245 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
cellular response to tumor necrosis factor GO:0071356 46 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
negative regulation of hormone secretion GO:0046888 46 0.028
muscle system process GO:0003012 115 0.028
protein transport GO:0015031 132 0.028
synaptic transmission GO:0007268 235 0.028
neurological system process GO:0050877 219 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
regulation of membrane potential GO:0042391 110 0.027
negative regulation of metabolic process GO:0009892 331 0.026
cellular component biogenesis GO:0044085 368 0.026
negative regulation of cell communication GO:0010648 158 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
behavioral response to nicotine GO:0035095 2 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
cellular potassium ion transport GO:0071804 72 0.026
regulation of peptide transport GO:0090087 87 0.026
circulatory system process GO:0003013 183 0.026
peptide transport GO:0015833 97 0.025
response to ethanol GO:0045471 162 0.025
Rat
regulation of peptide secretion GO:0002791 82 0.025
regulation of hormone secretion GO:0046883 106 0.025
heart process GO:0003015 57 0.025
cellular calcium ion homeostasis GO:0006874 160 0.025
response to external biotic stimulus GO:0043207 221 0.024
positive regulation of gene expression GO:0010628 244 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
cell communication involved in cardiac conduction GO:0086065 2 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
positive regulation of developmental process GO:0051094 283 0.024
Rat
regulation of molecular function GO:0065009 398 0.024
regulation of rna metabolic process GO:0051252 391 0.024
regulation of signal transduction GO:0009966 318 0.023
cellular ketone metabolic process GO:0042180 51 0.023
behavior GO:0007610 205 0.023
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
protein complex subunit organization GO:0071822 302 0.023
rna biosynthetic process GO:0032774 380 0.022
muscle cell proliferation GO:0033002 84 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
bile acid biosynthetic process GO:0006699 3 0.022
calcium ion transport GO:0006816 131 0.022
positive regulation of signaling GO:0023056 270 0.022
regulation of peptide hormone secretion GO:0090276 80 0.022
single organism reproductive process GO:0044702 297 0.021
macromolecular complex assembly GO:0065003 273 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
cellular response to molecule of bacterial origin GO:0071219 56 0.021
signal release GO:0023061 145 0.021
regulation of blood vessel size GO:0050880 89 0.021
single organism intracellular transport GO:1902582 166 0.021
circulatory system development GO:0072359 134 0.020
regulation of phosphorylation GO:0042325 248 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
response to heat GO:0009408 60 0.020
potassium ion transport GO:0006813 97 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
cell cell signaling GO:0007267 335 0.020
chemical homeostasis GO:0048878 292 0.020
regulation of kinase activity GO:0043549 117 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
positive regulation of cell communication GO:0010647 271 0.020
response to other organism GO:0051707 220 0.020
hormone transport GO:0009914 121 0.020
regulation of hormone levels GO:0010817 187 0.020
regulation of transcription regulatory region dna binding GO:2000677 4 0.019
central nervous system development GO:0007417 311 0.019
oxoacid metabolic process GO:0043436 290 0.019
metal ion transport GO:0030001 289 0.019
cellular ion homeostasis GO:0006873 184 0.019
response to ketone GO:1901654 182 0.019
protein homooligomerization GO:0051260 91 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
sequestering of metal ion GO:0051238 9 0.019
organophosphate metabolic process GO:0019637 370 0.019
protein phosphorylation GO:0006468 345 0.019
cytoplasmic transport GO:0016482 115 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
neuron death GO:0070997 127 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
response to monosaccharide GO:0034284 159 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
endocytosis GO:0006897 84 0.018
neuron differentiation GO:0030182 368 0.018
protein localization GO:0008104 191 0.018
myeloid leukocyte activation GO:0002274 36 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
exocytosis GO:0006887 60 0.018
negative regulation of secretion by cell GO:1903531 72 0.018
single organism biosynthetic process GO:0044711 342 0.018
positive regulation of cell activation GO:0050867 34 0.018
regulation of transferase activity GO:0051338 123 0.018
establishment of protein localization GO:0045184 141 0.018
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
divalent inorganic cation transport GO:0072511 134 0.017
cell morphogenesis GO:0000902 142 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
striated muscle contraction GO:0006941 44 0.017
regulation of catalytic activity GO:0050790 304 0.017
insulin secretion GO:0030073 69 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
protein complex assembly GO:0006461 263 0.017
regulation of secretion GO:0051046 224 0.017
regulation of intracellular transport GO:0032386 65 0.017
divalent metal ion transport GO:0070838 132 0.017
negative regulation of signaling GO:0023057 157 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.016
cell projection morphogenesis GO:0048858 123 0.016
peptide secretion GO:0002790 86 0.016
metal ion homeostasis GO:0055065 186 0.016
cell fate determination GO:0001709 2 0.016
vascular process in circulatory system GO:0003018 96 0.016
alpha amino acid metabolic process GO:1901605 71 0.016
acute inflammatory response to antigenic stimulus GO:0002438 9 0.016
regulation of protein modification process GO:0031399 194 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
cardiac muscle cell contraction GO:0086003 10 0.016
single organism organelle organization GO:1902589 180 0.016
response to mechanical stimulus GO:0009612 134 0.016
positive regulation of cell motility GO:2000147 97 0.016
positive regulation of response to external stimulus GO:0032103 51 0.016
secretion GO:0046903 307 0.016
regulation of fat cell differentiation GO:0045598 3 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
organic acid transport GO:0015849 116 0.016
regulation of neuron death GO:1901214 115 0.016
cellular macromolecule localization GO:0070727 122 0.016
vasodilation GO:0042311 44 0.015
positive regulation of signal transduction GO:0009967 175 0.015
neural crest cell migration GO:0001755 1 0.015
protein oligomerization GO:0051259 191 0.015
regulation of synaptic transmission GO:0050804 141 0.015
negative regulation of cell death GO:0060548 229 0.015
regulation of protein metabolic process GO:0051246 289 0.015
cellular component morphogenesis GO:0032989 155 0.015
purine containing compound metabolic process GO:0072521 253 0.015
peptide hormone secretion GO:0030072 84 0.015
receptor mediated endocytosis GO:0006898 42 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of blood pressure GO:0008217 83 0.015
response to tumor necrosis factor GO:0034612 56 0.015
response to ph GO:0009268 27 0.015
cell cycle GO:0007049 101 0.015
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.015
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.015
brain renin angiotensin system GO:0002035 3 0.015
response to hexose GO:0009746 144 0.015
peptidyl amino acid modification GO:0018193 126 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
regulation of muscle contraction GO:0006937 53 0.014
neural crest cell differentiation GO:0014033 2 0.014
head development GO:0060322 247 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
regulation of response to external stimulus GO:0032101 106 0.014
positive regulation of leukocyte migration GO:0002687 21 0.014
single organism behavior GO:0044708 130 0.014
cellular response to peptide GO:1901653 133 0.014
rhythmic process GO:0048511 156 0.014
regulation of cell development GO:0060284 263 0.014
Rat
sequestering of calcium ion GO:0051208 8 0.014
cell cycle checkpoint GO:0000075 2 0.014
regulation of immune system process GO:0002682 123 0.014
positive regulation of homeostatic process GO:0032846 49 0.014
organic substance catabolic process GO:1901575 316 0.014
regulation of catabolic process GO:0009894 113 0.014
cellular catabolic process GO:0044248 295 0.014
positive regulation of calcium ion transport GO:0051928 36 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
reproduction GO:0000003 245 0.014
regulation of blood circulation GO:1903522 110 0.013
axis specification GO:0009798 4 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
cell projection organization GO:0030030 302 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cell part morphogenesis GO:0032990 123 0.013
protein heterooligomerization GO:0051291 89 0.013
regulation of neuron projection development GO:0010975 161 0.013
leukocyte mediated immunity GO:0002443 28 0.013
cellular protein localization GO:0034613 122 0.013
positive regulation of leukocyte degranulation GO:0043302 4 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
cellular response to fluid shear stress GO:0071498 4 0.013
negative regulation of transport GO:0051051 136 0.013
spindle organization GO:0007051 2 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of immune response GO:0050778 42 0.013
positive regulation of molecular function GO:0044093 230 0.013
negative regulation of peptide hormone secretion GO:0090278 30 0.013
sterol homeostasis GO:0055092 3 0.013
response to ammonium ion GO:0060359 71 0.013
neuron projection morphogenesis GO:0048812 122 0.013
multicellular organism reproduction GO:0032504 233 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
cardiovascular system development GO:0072358 134 0.013
proteolysis GO:0006508 175 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
neural crest cell development GO:0014032 2 0.012
regulation of neurogenesis GO:0050767 247 0.012
positive regulation of cytoplasmic transport GO:1903651 32 0.012
regulation of regulated secretory pathway GO:1903305 7 0.012
mast cell activation GO:0045576 15 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
regulation of secretion by cell GO:1903530 208 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
action potential GO:0001508 54 0.012
nucleotide metabolic process GO:0009117 279 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
Rat
response to hypoxia GO:0001666 231 0.012
actin nucleation GO:0045010 2 0.012
response to lipopolysaccharide GO:0032496 191 0.012
cholesterol homeostasis GO:0042632 3 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of ion transport GO:0043270 94 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
response to starvation GO:0042594 59 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
regulation of insulin secretion GO:0050796 65 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
positive regulation of intracellular transport GO:0032388 39 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
response to peptide hormone GO:0043434 278 0.012
dicarboxylic acid metabolic process GO:0043648 42 0.012
myeloid cell activation involved in immune response GO:0002275 13 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
sexual reproduction GO:0019953 148 0.011
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
response to biotic stimulus GO:0009607 226 0.011
sensory perception of bitter taste GO:0050913 4 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
limb morphogenesis GO:0035108 4 0.011
mapk cascade GO:0000165 140 0.011
gliogenesis GO:0042063 93 0.011
positive regulation of mast cell activation GO:0033005 4 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
camp biosynthetic process GO:0006171 47 0.011
nitrogen compound transport GO:0071705 229 0.011
glutathione transport GO:0034635 2 0.011
development of primary sexual characteristics GO:0045137 107 0.011
heart morphogenesis GO:0003007 3 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
female sex differentiation GO:0046660 59 0.011
regulation of response to food GO:0032095 11 0.011
arp2 3 complex mediated actin nucleation GO:0034314 2 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
eosinophil chemotaxis GO:0048245 3 0.011
regulation of appetite GO:0032098 8 0.011
regulation of calcium ion transport into cytosol GO:0010522 25 0.011
tissue development GO:0009888 252 0.011
Rat
multi organism reproductive process GO:0044703 262 0.011
renal sodium excretion GO:0035812 20 0.010
regulation of nervous system development GO:0051960 264 0.010
organic anion transport GO:0015711 132 0.010
negative regulation of organ growth GO:0046621 3 0.010
monocarboxylic acid transport GO:0015718 52 0.010
leukocyte degranulation GO:0043299 12 0.010
cellular response to external stimulus GO:0071496 118 0.010
cofactor metabolic process GO:0051186 95 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of programmed cell death GO:0043067 341 0.010
negative regulation of homeostatic process GO:0032845 47 0.010
muscle contraction GO:0006936 88 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of defense response GO:0031347 68 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
quaternary ammonium group transport GO:0015697 6 0.010
regulation of heart contraction GO:0008016 48 0.010
apoptotic process GO:0006915 381 0.010
ion transmembrane transport GO:0034220 365 0.010
tripeptide transport GO:0042939 2 0.010

Neu3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 0 0.065
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011