Rattus norvegicus

0 known processes

Plekhh2

pleckstrin homology domain containing, family H (with MyTH4 domain) member 2

(Aliases: RGD1304935)

Plekhh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.073
organic acid metabolic process GO:0006082 292 0.064
cellular amino acid metabolic process GO:0006520 107 0.061
single organism reproductive process GO:0044702 297 0.047
transcription dna templated GO:0006351 377 0.046
organophosphate metabolic process GO:0019637 370 0.046
carboxylic acid metabolic process GO:0019752 289 0.044
amine metabolic process GO:0009308 38 0.042
cellular amine metabolic process GO:0044106 38 0.042
regulation of cellular ketone metabolic process GO:0010565 27 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.038
secretion GO:0046903 307 0.037
protein phosphorylation GO:0006468 345 0.036
intracellular signal transduction GO:0035556 314 0.036
organic substance catabolic process GO:1901575 316 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
regulation of hormone levels GO:0010817 187 0.035
response to inorganic substance GO:0010035 377 0.035
purine containing compound metabolic process GO:0072521 253 0.034
cellular ketone metabolic process GO:0042180 51 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cellular catabolic process GO:0044248 295 0.033
response to decreased oxygen levels GO:0036293 237 0.032
synaptic transmission GO:0007268 235 0.031
homeostatic process GO:0042592 331 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
purine nucleotide biosynthetic process GO:0006164 83 0.029
programmed cell death GO:0012501 392 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
reproductive process GO:0022414 372 0.028
rna biosynthetic process GO:0032774 380 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
apoptotic process GO:0006915 381 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
protein complex subunit organization GO:0071822 302 0.026
secretion by cell GO:0032940 248 0.026
response to extracellular stimulus GO:0009991 380 0.025
regulation of rna metabolic process GO:0051252 391 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
regulation of apoptotic process GO:0042981 335 0.025
multi organism reproductive process GO:0044703 262 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
chemical homeostasis GO:0048878 292 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
ras protein signal transduction GO:0007265 29 0.024
regulation of secretion by cell GO:1903530 208 0.024
nucleotide metabolic process GO:0009117 279 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
ion transmembrane transport GO:0034220 365 0.023
response to growth factor GO:0070848 189 0.023
cellular component assembly GO:0022607 360 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
regulation of programmed cell death GO:0043067 341 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
positive regulation of signaling GO:0023056 270 0.022
signal release GO:0023061 145 0.022
response to bacterium GO:0009617 200 0.021
organelle organization GO:0006996 266 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
regulation of cellular localization GO:0060341 263 0.021
regulation of transcription dna templated GO:0006355 374 0.021
negative regulation of metabolic process GO:0009892 331 0.021
positive regulation of nervous system development GO:0051962 178 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
single organism catabolic process GO:0044712 283 0.020
response to external biotic stimulus GO:0043207 221 0.020
rna metabolic process GO:0016070 406 0.020
cell cell signaling GO:0007267 335 0.020
transmembrane transport GO:0055085 412 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
hormone transport GO:0009914 121 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
positive regulation of molecular function GO:0044093 230 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
regulation of system process GO:0044057 208 0.019
sexual reproduction GO:0019953 148 0.019
macromolecule localization GO:0033036 252 0.019
multicellular organism reproduction GO:0032504 233 0.019
single organism biosynthetic process GO:0044711 342 0.018
central nervous system development GO:0007417 311 0.018
anion transport GO:0006820 178 0.018
regulation of phosphorylation GO:0042325 248 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
regulation of molecular function GO:0065009 398 0.018
cellular response to stress GO:0033554 269 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
regulation of ion transport GO:0043269 245 0.018
negative regulation of gene expression GO:0010629 199 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
response to corticosteroid GO:0031960 235 0.018
catabolic process GO:0009056 351 0.018
cellular component biogenesis GO:0044085 368 0.018
response to peptide hormone GO:0043434 278 0.018
neuron differentiation GO:0030182 368 0.018
response to nutrient levels GO:0031667 370 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
regulation of cell migration GO:0030334 128 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
regulation of nervous system development GO:0051960 264 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
organic anion transport GO:0015711 132 0.017
response to oxidative stress GO:0006979 186 0.017
regulation of protein modification process GO:0031399 194 0.017
regulation of membrane potential GO:0042391 110 0.017
regulation of cell differentiation GO:0045595 320 0.017
response to peptide GO:1901652 292 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
regulation of cell proliferation GO:0042127 359 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
positive regulation of developmental process GO:0051094 283 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
regulation of neurogenesis GO:0050767 247 0.016
response to oxygen levels GO:0070482 265 0.016
nucleic acid templated transcription GO:0097659 379 0.016
cell migration GO:0016477 197 0.016
ossification GO:0001503 70 0.016
ion homeostasis GO:0050801 212 0.016
regulation of catalytic activity GO:0050790 304 0.016
peptide hormone secretion GO:0030072 84 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
nitrogen compound transport GO:0071705 229 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
regulation of phosphate metabolic process GO:0019220 349 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
response to metal ion GO:0010038 253 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
negative regulation of transport GO:0051051 136 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
defense response GO:0006952 194 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
single organism organelle organization GO:1902589 180 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
response to ketone GO:1901654 182 0.015
reproduction GO:0000003 245 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
response to biotic stimulus GO:0009607 226 0.014
aging GO:0007568 241 0.014
axis specification GO:0009798 4 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
response to hexose GO:0009746 144 0.014
protein complex biogenesis GO:0070271 263 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
gamete generation GO:0007276 124 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
action potential GO:0001508 54 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
peptidyl amino acid modification GO:0018193 126 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
camp metabolic process GO:0046058 63 0.014
response to alkaloid GO:0043279 132 0.014
amide transport GO:0042886 105 0.014
protein complex assembly GO:0006461 263 0.014
response to estradiol GO:0032355 164 0.014
regulation of cell projection organization GO:0031344 175 0.014
cell adhesion GO:0007155 110 0.014
response to hypoxia GO:0001666 231 0.014
regulation of peptide transport GO:0090087 87 0.014
cellular chemical homeostasis GO:0055082 247 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
response to ethanol GO:0045471 162 0.013
alcohol metabolic process GO:0006066 77 0.013
nucleoside metabolic process GO:0009116 179 0.013
positive regulation of hormone secretion GO:0046887 65 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cellular homeostasis GO:0019725 252 0.013
negative regulation of innate immune response GO:0045824 4 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
actin cytoskeleton organization GO:0030036 73 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
response to other organism GO:0051707 220 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
peptide secretion GO:0002790 86 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of secretion GO:0051046 224 0.013
cation homeostasis GO:0055080 195 0.013
positive regulation of cell communication GO:0010647 271 0.013
chemosensory behavior GO:0007635 2 0.012
regulation of cell development GO:0060284 263 0.012
hormone secretion GO:0046879 115 0.012
cell projection organization GO:0030030 302 0.012
cell type specific apoptotic process GO:0097285 134 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
regulation of transferase activity GO:0051338 123 0.012
positive regulation of peptide secretion GO:0002793 52 0.012
bmp signaling pathway GO:0030509 4 0.012
cellular component morphogenesis GO:0032989 155 0.012
olfactory behavior GO:0042048 2 0.012
response to amino acid GO:0043200 75 0.012
cell part morphogenesis GO:0032990 123 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
organophosphate catabolic process GO:0046434 148 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
cellular component movement GO:0006928 248 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of cell adhesion GO:0030155 52 0.012
response to carbohydrate GO:0009743 183 0.012
response to cytokine GO:0034097 215 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
positive regulation of gene expression GO:0010628 244 0.012
biological adhesion GO:0022610 110 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
sensory perception of pain GO:0019233 73 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
metal ion homeostasis GO:0055065 186 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
cation transport GO:0006812 382 0.011
neuron projection development GO:0031175 273 0.011
regulation of hormone secretion GO:0046883 106 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of cell development GO:0010720 176 0.011
positive regulation of transport GO:0051050 245 0.011
positive regulation of protein modification process GO:0031401 142 0.011
heart morphogenesis GO:0003007 3 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
positive regulation of signal transduction GO:0009967 175 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of cellular component movement GO:0051270 150 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
negative regulation of developmental process GO:0051093 125 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
cellular response to external stimulus GO:0071496 118 0.011
immune response GO:0006955 104 0.011
cell cycle checkpoint GO:0000075 2 0.011
oxidation reduction process GO:0055114 304 0.011
brain development GO:0007420 247 0.011
nucleotide catabolic process GO:0009166 139 0.011
proteolysis GO:0006508 175 0.011
protein oligomerization GO:0051259 191 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
negative regulation of cell death GO:0060548 229 0.010
sex differentiation GO:0007548 113 0.010
male gamete generation GO:0048232 99 0.010
localization of cell GO:0051674 202 0.010
actin filament based process GO:0030029 86 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
regulation of blood circulation GO:1903522 110 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
limb morphogenesis GO:0035108 4 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010

Plekhh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.033
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.016
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
central nervous system disease DOID:331 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011