Rattus norvegicus

0 known processes

Lass4

LAG1 homolog, ceramide synthase 4

Lass4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.078
neuron development GO:0048666 286 0.077
regulation of molecular function GO:0065009 398 0.075
brain development GO:0007420 247 0.071
rna metabolic process GO:0016070 406 0.069
nucleic acid templated transcription GO:0097659 379 0.069
programmed cell death GO:0012501 392 0.069
regulation of phosphorus metabolic process GO:0051174 349 0.064
protein phosphorylation GO:0006468 345 0.060
cellular amino acid metabolic process GO:0006520 107 0.058
regulation of rna metabolic process GO:0051252 391 0.058
cell type specific apoptotic process GO:0097285 134 0.056
intracellular signal transduction GO:0035556 314 0.053
rna biosynthetic process GO:0032774 380 0.051
single organism reproductive process GO:0044702 297 0.051
apoptotic process GO:0006915 381 0.050
negative regulation of metabolic process GO:0009892 331 0.050
central nervous system development GO:0007417 311 0.049
organophosphate metabolic process GO:0019637 370 0.048
regulation of rna biosynthetic process GO:2001141 381 0.048
regulation of programmed cell death GO:0043067 341 0.047
cell projection organization GO:0030030 302 0.046
oxoacid metabolic process GO:0043436 290 0.045
regulation of intracellular signal transduction GO:1902531 218 0.045
transcription dna templated GO:0006351 377 0.044
reproductive process GO:0022414 372 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
head development GO:0060322 247 0.042
tissue development GO:0009888 252 0.041
aging GO:0007568 241 0.040
Yeast
carbohydrate derivative metabolic process GO:1901135 346 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
regulation of catalytic activity GO:0050790 304 0.037
regulation of phosphorylation GO:0042325 248 0.036
response to nutrient levels GO:0031667 370 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
renal system development GO:0072001 67 0.035
regulation of transcription dna templated GO:0006355 374 0.035
organelle organization GO:0006996 266 0.034
single organism organelle organization GO:1902589 180 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.033
cellular ketone metabolic process GO:0042180 51 0.033
regulation of apoptotic process GO:0042981 335 0.033
homeostatic process GO:0042592 331 0.032
cardiovascular system development GO:0072358 134 0.032
regulation of protein metabolic process GO:0051246 289 0.032
regulation of cellular component organization GO:0051128 368 0.031
organic anion transport GO:0015711 132 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
multi organism reproductive process GO:0044703 262 0.031
positive regulation of molecular function GO:0044093 230 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
organic acid metabolic process GO:0006082 292 0.030
cellular component assembly GO:0022607 360 0.030
regulation of protein modification process GO:0031399 194 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
cellular component morphogenesis GO:0032989 155 0.030
catabolic process GO:0009056 351 0.029
regulation of cell proliferation GO:0042127 359 0.029
eye morphogenesis GO:0048592 4 0.029
cellular amine metabolic process GO:0044106 38 0.028
nitrogen compound transport GO:0071705 229 0.028
positive regulation of catalytic activity GO:0043085 184 0.027
multicellular organism reproduction GO:0032504 233 0.027
negative regulation of gene expression GO:0010629 199 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
sex differentiation GO:0007548 113 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
reproductive structure development GO:0048608 128 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
cellular component biogenesis GO:0044085 368 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
urogenital system development GO:0001655 78 0.025
macromolecular complex assembly GO:0065003 273 0.025
positive regulation of gene expression GO:0010628 244 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
synaptic transmission GO:0007268 235 0.025
reproductive system development GO:0061458 128 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
regulation of signal transduction GO:0009966 318 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
regulation of neuron differentiation GO:0045664 208 0.025
positive regulation of rna metabolic process GO:0051254 203 0.024
purine containing compound metabolic process GO:0072521 253 0.024
cell motility GO:0048870 202 0.024
gland development GO:0048732 155 0.024
b cell differentiation GO:0030183 2 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
cellular component movement GO:0006928 248 0.024
regulation of neurogenesis GO:0050767 247 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of signal transduction GO:0009967 175 0.023
amine metabolic process GO:0009308 38 0.023
lipid metabolic process GO:0006629 283 0.023
Yeast Mouse
developmental process involved in reproduction GO:0003006 159 0.023
regulation of nervous system development GO:0051960 264 0.023
neuron projection development GO:0031175 273 0.022
regulation of hydrolase activity GO:0051336 143 0.022
response to wounding GO:0009611 254 0.022
anion transport GO:0006820 178 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
neuron differentiation GO:0030182 368 0.022
secretion GO:0046903 307 0.022
organic substance catabolic process GO:1901575 316 0.022
dephosphorylation GO:0016311 98 0.022
negative regulation of cell communication GO:0010648 158 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
regulation of purine nucleotide metabolic process GO:1900542 115 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
regulation of organelle organization GO:0033043 80 0.021
cellular catabolic process GO:0044248 295 0.021
cell projection morphogenesis GO:0048858 123 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
nucleotide metabolic process GO:0009117 279 0.020
mapk cascade GO:0000165 140 0.020
cellular response to lipid GO:0071396 201 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
cation homeostasis GO:0055080 195 0.020
regulation of hormone levels GO:0010817 187 0.020
protein complex subunit organization GO:0071822 302 0.019
cellular lipid metabolic process GO:0044255 208 0.019
Yeast Mouse
organonitrogen compound catabolic process GO:1901565 179 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
response to inorganic substance GO:0010035 377 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
reproduction GO:0000003 245 0.019
chemical homeostasis GO:0048878 292 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
response to ketone GO:1901654 182 0.019
macromolecule localization GO:0033036 252 0.019
response to estrogen GO:0043627 232 0.019
regulation of mapk cascade GO:0043408 116 0.019
proteolysis GO:0006508 175 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
cell morphogenesis GO:0000902 142 0.018
gonad development GO:0008406 104 0.018
positive regulation of protein modification process GO:0031401 142 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of cell development GO:0060284 263 0.018
regulation of cell differentiation GO:0045595 320 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
regulation of system process GO:0044057 208 0.018
cellular homeostasis GO:0019725 252 0.018
gamete generation GO:0007276 124 0.018
embryonic pattern specification GO:0009880 1 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
neurological system process GO:0050877 219 0.018
positive regulation of secretion GO:0051047 140 0.018
cell cell signaling GO:0007267 335 0.018
ras protein signal transduction GO:0007265 29 0.018
development of primary sexual characteristics GO:0045137 107 0.017
biological adhesion GO:0022610 110 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
axon development GO:0061564 96 0.017
response to extracellular stimulus GO:0009991 380 0.017
rhythmic process GO:0048511 156 0.017
regulation of cellular localization GO:0060341 263 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
motor neuron axon guidance GO:0008045 1 0.017
single organism biosynthetic process GO:0044711 342 0.017
Yeast Mouse
single organism catabolic process GO:0044712 283 0.017
response to growth factor GO:0070848 189 0.017
blood circulation GO:0008015 183 0.017
positive regulation of cell proliferation GO:0008284 249 0.016
circulatory system process GO:0003013 183 0.016
regeneration GO:0031099 163 0.016
macromolecule catabolic process GO:0009057 58 0.016
response to decreased oxygen levels GO:0036293 237 0.016
circulatory system development GO:0072359 134 0.016
kidney development GO:0001822 67 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
growth GO:0040007 165 0.016
response to nutrient GO:0007584 248 0.016
cell part morphogenesis GO:0032990 123 0.016
response to oxygen levels GO:0070482 265 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
anterior posterior pattern specification GO:0009952 1 0.016
cellular response to stress GO:0033554 269 0.015
negative regulation of cell death GO:0060548 229 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
neural crest cell development GO:0014032 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
regulation of cell projection organization GO:0031344 175 0.015
neuron apoptotic process GO:0051402 88 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of kinase activity GO:0043549 117 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
neuronal action potential GO:0019228 35 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
regulation of transferase activity GO:0051338 123 0.015
negative regulation of molecular function GO:0044092 133 0.015
cellular chemical homeostasis GO:0055082 247 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
multi multicellular organism process GO:0044706 138 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
male sex differentiation GO:0046661 64 0.015
positive regulation of nucleotide catabolic process GO:0030813 53 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
negative regulation of cell development GO:0010721 82 0.015
response to acid chemical GO:0001101 222 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
cellular response to hormone stimulus GO:0032870 247 0.014
glycerolipid metabolic process GO:0046486 67 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
cell cycle GO:0007049 101 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
axis specification GO:0009798 4 0.014
positive regulation of cell communication GO:0010647 271 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
response to estradiol GO:0032355 164 0.014
metal ion transport GO:0030001 289 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
mesoderm development GO:0007498 2 0.014
protein complex biogenesis GO:0070271 263 0.014
cellular cation homeostasis GO:0030003 180 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
Yeast Mouse
negative regulation of protein metabolic process GO:0051248 114 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
axonogenesis GO:0007409 71 0.014
cellular ion homeostasis GO:0006873 184 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
peptidyl amino acid modification GO:0018193 126 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
positive regulation of nervous system development GO:0051962 178 0.013
muscle cell proliferation GO:0033002 84 0.013
positive regulation of signaling GO:0023056 270 0.013
intracellular transport GO:0046907 185 0.013
regulation of anatomical structure size GO:0090066 135 0.013
response to other organism GO:0051707 220 0.013
heart morphogenesis GO:0003007 3 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
defense response GO:0006952 194 0.013
bmp signaling pathway GO:0030509 4 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
heterocycle catabolic process GO:0046700 167 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
regulation of protein kinase activity GO:0045859 105 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
response to hypoxia GO:0001666 231 0.013
response to metal ion GO:0010038 253 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
response to toxic substance GO:0009636 133 0.013
negative regulation of transport GO:0051051 136 0.013
negative regulation of signaling GO:0023057 157 0.012
transmembrane transport GO:0055085 412 0.012
cellular response to acid chemical GO:0071229 75 0.012
negative regulation of developmental process GO:0051093 125 0.012
protein complex assembly GO:0006461 263 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
single organism intracellular transport GO:1902582 166 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
response to ethanol GO:0045471 162 0.012
neuron projection morphogenesis GO:0048812 122 0.012
regulation of secretion by cell GO:1903530 208 0.012
positive regulation of cell death GO:0010942 184 0.012
regulation of tube size GO:0035150 89 0.012
negative regulation of signal transduction GO:0009968 83 0.012
organ formation GO:0048645 3 0.012
regulation of neuron death GO:1901214 115 0.012
lipid biosynthetic process GO:0008610 128 0.012
Yeast Mouse
regulation of body fluid levels GO:0050878 90 0.012
response to alkaloid GO:0043279 132 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
developmental growth GO:0048589 100 0.012
cytoplasmic transport GO:0016482 115 0.012
salivary gland development GO:0007431 3 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
cation transport GO:0006812 382 0.012
hormone transport GO:0009914 121 0.012
hepaticobiliary system development GO:0061008 90 0.012
response to camp GO:0051591 91 0.012
localization of cell GO:0051674 202 0.012
cytoskeleton organization GO:0007010 111 0.012
gastrulation GO:0007369 2 0.012
regulation of metanephros development GO:0072215 4 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
regulation of cellular component biogenesis GO:0044087 86 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
calcium ion homeostasis GO:0055074 162 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
response to purine containing compound GO:0014074 126 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
male gonad development GO:0008584 59 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
phospholipid metabolic process GO:0006644 61 0.011
negative regulation of nervous system development GO:0051961 79 0.011
response to biotic stimulus GO:0009607 226 0.011
positive regulation of kinase activity GO:0033674 77 0.011
nucleoside metabolic process GO:0009116 179 0.011
female pregnancy GO:0007565 122 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
actin filament based process GO:0030029 86 0.011
sexual reproduction GO:0019953 148 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
organic acid transport GO:0015849 116 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
vesicle mediated transport GO:0016192 181 0.011
response to organophosphorus GO:0046683 102 0.011
organelle localization GO:0051640 55 0.011
establishment of protein localization GO:0045184 141 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
positive regulation of transport GO:0051050 245 0.011
response to cytokine GO:0034097 215 0.011
cellular macromolecular complex assembly GO:0034622 58 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
autonomic nervous system development GO:0048483 3 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
ion transmembrane transport GO:0034220 365 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
behavioral response to ethanol GO:0048149 1 0.010
response to corticosteroid GO:0031960 235 0.010
positive regulation of cell development GO:0010720 176 0.010
inflammatory response GO:0006954 150 0.010
muscle structure development GO:0061061 87 0.010
nucleoside catabolic process GO:0009164 126 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
lipid storage GO:0019915 1 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
protein autophosphorylation GO:0046777 66 0.010

Lass4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
sensory system disease DOID:0050155 0 0.012