Rattus norvegicus

0 known processes

Brsk2

BR serine/threonine kinase 2

Brsk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.157
positive regulation of signaling GO:0023056 270 0.111
anatomical structure morphogenesis GO:0009653 298 0.106
Mouse
macromolecular complex subunit organization GO:0043933 339 0.085
regulation of signal transduction GO:0009966 318 0.084
positive regulation of signal transduction GO:0009967 175 0.083
protein complex biogenesis GO:0070271 263 0.072
positive regulation of developmental process GO:0051094 283 0.070
carbohydrate derivative metabolic process GO:1901135 346 0.069
Fly
regulation of phosphorylation GO:0042325 248 0.063
ribose phosphate metabolic process GO:0019693 235 0.063
neuron differentiation GO:0030182 368 0.062
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.061
transmembrane transport GO:0055085 412 0.061
muscle system process GO:0003012 115 0.060
transcription dna templated GO:0006351 377 0.059
purine containing compound metabolic process GO:0072521 253 0.059
transcription from rna polymerase ii promoter GO:0006366 252 0.058
synaptic transmission GO:0007268 235 0.058
Rat
axonogenesis GO:0007409 71 0.057
Mouse
neuron development GO:0048666 286 0.057
Mouse
protein phosphorylation GO:0006468 345 0.056
Human Mouse Rat
purine nucleoside catabolic process GO:0006152 124 0.056
purine nucleotide metabolic process GO:0006163 229 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
nucleic acid templated transcription GO:0097659 379 0.054
positive regulation of cell communication GO:0010647 271 0.054
macromolecule localization GO:0033036 252 0.054
cell projection morphogenesis GO:0048858 123 0.053
Mouse
actin filament based process GO:0030029 86 0.052
Human
muscle contraction GO:0006936 88 0.052
organophosphate catabolic process GO:0046434 148 0.051
cation transport GO:0006812 382 0.051
regulation of purine nucleotide metabolic process GO:1900542 115 0.051
single organism biosynthetic process GO:0044711 342 0.051
purine containing compound catabolic process GO:0072523 138 0.050
cellular catabolic process GO:0044248 295 0.049
neuron projection morphogenesis GO:0048812 122 0.047
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 122 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
carbohydrate derivative catabolic process GO:1901136 147 0.047
regulation of secretion GO:0051046 224 0.045
Human Mouse
glycosyl compound metabolic process GO:1901657 182 0.045
intracellular signal transduction GO:0035556 314 0.044
Human
apoptotic process GO:0006915 381 0.043
Human
regulation of molecular function GO:0065009 398 0.043
catabolic process GO:0009056 351 0.043
rna biosynthetic process GO:0032774 380 0.042
heterocycle catabolic process GO:0046700 167 0.042
regulation of cellular localization GO:0060341 263 0.042
Human Mouse
purine ribonucleotide catabolic process GO:0009154 136 0.042
nucleoside triphosphate catabolic process GO:0009143 123 0.042
cellular nitrogen compound catabolic process GO:0044270 163 0.041
regulation of neurogenesis GO:0050767 247 0.041
regulation of catabolic process GO:0009894 113 0.041
nucleoside phosphate catabolic process GO:1901292 140 0.041
response to growth factor GO:0070848 189 0.041
ribonucleotide catabolic process GO:0009261 136 0.040
nucleotide catabolic process GO:0009166 139 0.040
ribonucleotide metabolic process GO:0009259 231 0.040
nitrogen compound transport GO:0071705 229 0.039
Human Mouse
single organism reproductive process GO:0044702 297 0.039
protein transport GO:0015031 132 0.039
homeostatic process GO:0042592 331 0.039
Human Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.039
response to inorganic substance GO:0010035 377 0.039
rna metabolic process GO:0016070 406 0.038
purine ribonucleotide metabolic process GO:0009150 227 0.038
neuron projection development GO:0031175 273 0.037
Mouse
positive regulation of cell differentiation GO:0045597 217 0.036
nucleotide metabolic process GO:0009117 279 0.036
cell part morphogenesis GO:0032990 123 0.036
Mouse
organic substance catabolic process GO:1901575 316 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.036
cellular component morphogenesis GO:0032989 155 0.036
Mouse
nucleoside triphosphate metabolic process GO:0009141 144 0.035
regulation of catalytic activity GO:0050790 304 0.035
reproductive process GO:0022414 372 0.035
ribonucleoside metabolic process GO:0009119 174 0.035
glycosyl compound catabolic process GO:1901658 126 0.035
cellular component biogenesis GO:0044085 368 0.034
nucleobase containing compound catabolic process GO:0034655 152 0.034
positive regulation of nucleotide metabolic process GO:0045981 91 0.034
central nervous system development GO:0007417 311 0.033
negative regulation of cell death GO:0060548 229 0.032
regulation of hydrolase activity GO:0051336 143 0.032
protein complex subunit organization GO:0071822 302 0.031
positive regulation of molecular function GO:0044093 230 0.031
ribonucleoside triphosphate catabolic process GO:0009203 122 0.031
brain development GO:0007420 247 0.031
regulation of rna metabolic process GO:0051252 391 0.031
cell projection organization GO:0030030 302 0.031
Mouse
purine nucleotide catabolic process GO:0006195 136 0.031
cell morphogenesis involved in differentiation GO:0000904 119 0.030
Mouse
organelle organization GO:0006996 266 0.030
Human
positive regulation of multicellular organismal process GO:0051240 387 0.030
sensory perception GO:0007600 101 0.030
aromatic compound catabolic process GO:0019439 168 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
ribonucleoside triphosphate metabolic process GO:0009199 141 0.030
purine ribonucleoside catabolic process GO:0046130 124 0.030
response to metal ion GO:0010038 253 0.029
single organism catabolic process GO:0044712 283 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
locomotion GO:0040011 237 0.029
signal release GO:0023061 145 0.029
Human Mouse Rat
purine nucleoside metabolic process GO:0042278 169 0.029
regulation of system process GO:0044057 208 0.029
heart contraction GO:0060047 57 0.029
positive regulation of gene expression GO:0010628 244 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.029
positive regulation of response to stimulus GO:0048584 285 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
organic cyclic compound catabolic process GO:1901361 175 0.028
nucleoside metabolic process GO:0009116 179 0.028
regulation of neuron projection development GO:0010975 161 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
motor neuron axon guidance GO:0008045 1 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
cellular homeostasis GO:0019725 252 0.027
Human Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.027
glutamate receptor signaling pathway GO:0007215 43 0.027
programmed cell death GO:0012501 392 0.027
Human
organic anion transport GO:0015711 132 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of cell development GO:0060284 263 0.027
regulation of cellular catabolic process GO:0031329 101 0.027
aging GO:0007568 241 0.027
amine metabolic process GO:0009308 38 0.027
regulation of nucleotide catabolic process GO:0030811 65 0.026
regulation of nervous system development GO:0051960 264 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
negative regulation of metabolic process GO:0009892 331 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
response to wounding GO:0009611 254 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
protein localization GO:0008104 191 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
monovalent inorganic cation transport GO:0015672 172 0.025
regulation of programmed cell death GO:0043067 341 0.025
ribonucleoside catabolic process GO:0042454 126 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
single organism membrane organization GO:0044802 74 0.025
negative regulation of cell communication GO:0010648 158 0.025
gtp metabolic process GO:0046039 72 0.025
cell morphogenesis GO:0000902 142 0.025
Mouse
signal transduction by phosphorylation GO:0023014 144 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
guanosine containing compound catabolic process GO:1901069 71 0.024
intracellular transport GO:0046907 185 0.024
regulation of cell proliferation GO:0042127 359 0.024
positive regulation of synaptic transmission GO:0050806 62 0.024
cellular macromolecule localization GO:0070727 122 0.024
regulation of purine nucleotide catabolic process GO:0033121 65 0.023
regulation of neuron differentiation GO:0045664 208 0.023
potassium ion transport GO:0006813 97 0.023
axon development GO:0061564 96 0.023
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
nucleoside catabolic process GO:0009164 126 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
cytoskeleton organization GO:0007010 111 0.023
Human
guanosine containing compound metabolic process GO:1901068 74 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
response to radiation GO:0009314 137 0.022
regulation of response to external stimulus GO:0032101 106 0.022
regulation of membrane potential GO:0042391 110 0.022
mapk cascade GO:0000165 140 0.022
oxoacid metabolic process GO:0043436 290 0.022
carboxylic acid transport GO:0046942 115 0.022
cognition GO:0050890 92 0.022
regulation of transcription dna templated GO:0006355 374 0.022
gtp catabolic process GO:0006184 71 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
organophosphate metabolic process GO:0019637 370 0.021
organ formation GO:0048645 3 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
cellular component assembly GO:0022607 360 0.021
organic acid metabolic process GO:0006082 292 0.021
reproduction GO:0000003 245 0.021
regulation of secretion by cell GO:1903530 208 0.021
Human Mouse
cellular lipid metabolic process GO:0044255 208 0.020
protein complex assembly GO:0006461 263 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
response to light stimulus GO:0009416 52 0.020
establishment of protein localization GO:0045184 141 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.020
regulation of cell morphogenesis GO:0022604 77 0.019
positive regulation of cell development GO:0010720 176 0.019
response to nutrient levels GO:0031667 370 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
anion transport GO:0006820 178 0.019
circadian rhythm GO:0007623 88 0.019
chemical homeostasis GO:0048878 292 0.019
Human Mouse
carboxylic acid metabolic process GO:0019752 289 0.019
positive regulation of nucleotide catabolic process GO:0030813 53 0.019
lipid transport GO:0006869 61 0.019
regulation of hormone levels GO:0010817 187 0.019
Human Mouse
cell type specific apoptotic process GO:0097285 134 0.019
positive regulation of nervous system development GO:0051962 178 0.019
rhythmic process GO:0048511 156 0.019
response to corticosteroid GO:0031960 235 0.019
single organism behavior GO:0044708 130 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
ras protein signal transduction GO:0007265 29 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
Mouse
head development GO:0060322 247 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
positive regulation of peptide secretion GO:0002793 52 0.017
cation homeostasis GO:0055080 195 0.017
regulation of nucleoside metabolic process GO:0009118 66 0.017
regulation of cell differentiation GO:0045595 320 0.017
response to alkaloid GO:0043279 132 0.017
dendrite development GO:0016358 72 0.017
regulation of synaptic transmission GO:0050804 141 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
cellular protein localization GO:0034613 122 0.017
negative regulation of signaling GO:0023057 157 0.017
neurological system process GO:0050877 219 0.017
proteolysis GO:0006508 175 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
macromolecular complex assembly GO:0065003 273 0.017
cell motility GO:0048870 202 0.017
actin cytoskeleton organization GO:0030036 73 0.017
Human
organic hydroxy compound metabolic process GO:1901615 115 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
protein oligomerization GO:0051259 191 0.016
neuron projection guidance GO:0097485 24 0.016
cellular component movement GO:0006928 248 0.016
response to ethanol GO:0045471 162 0.016
single organism intracellular transport GO:1902582 166 0.016
regulation of apoptotic process GO:0042981 335 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
regulation of gtpase activity GO:0043087 57 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
sensory organ development GO:0007423 74 0.016
cellular response to stress GO:0033554 269 0.016
Human
chemotaxis GO:0006935 66 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
Fly
cellular response to oxygen containing compound GO:1901701 386 0.016
Human Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
taxis GO:0042330 67 0.015
positive regulation of catabolic process GO:0009896 78 0.015
regulation of protein kinase activity GO:0045859 105 0.015
dephosphorylation GO:0016311 98 0.015
developmental process involved in reproduction GO:0003006 159 0.015
muscle structure development GO:0061061 87 0.015
regulation of ion transport GO:0043269 245 0.015
protein homooligomerization GO:0051260 91 0.015
calcium ion homeostasis GO:0055074 162 0.015
heart morphogenesis GO:0003007 3 0.015
camp metabolic process GO:0046058 63 0.015
regulation of kinase activity GO:0043549 117 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
regulation of mapk cascade GO:0043408 116 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of protein transport GO:0051223 68 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
axis specification GO:0009798 4 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
exploration behavior GO:0035640 1 0.014
negative regulation of cell development GO:0010721 82 0.014
organic acid transport GO:0015849 116 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
regulation of transferase activity GO:0051338 123 0.014
regulation of anatomical structure size GO:0090066 135 0.014
regulation of organ formation GO:0003156 2 0.014
multicellular organism reproduction GO:0032504 233 0.014
regulation of protein metabolic process GO:0051246 289 0.014
multicellular organism growth GO:0035264 1 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
adult locomotory behavior GO:0008344 4 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of locomotion GO:0040012 148 0.014
cellular ion homeostasis GO:0006873 184 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
secretion GO:0046903 307 0.014
Human Mouse Rat
carbohydrate homeostasis GO:0033500 75 0.014
Human Mouse
ion homeostasis GO:0050801 212 0.014
response to oxygen levels GO:0070482 265 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
positive regulation of cell proliferation GO:0008284 249 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
cellular ketone metabolic process GO:0042180 51 0.013
regulation of peptide secretion GO:0002791 82 0.013
Human Mouse
negative regulation of catalytic activity GO:0043086 103 0.013
multi organism reproductive process GO:0044703 262 0.013
mechanoreceptor differentiation GO:0042490 2 0.013
metal ion transport GO:0030001 289 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
neuron fate commitment GO:0048663 4 0.013
gamete generation GO:0007276 124 0.013
regulation of gtp catabolic process GO:0033124 58 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
regulation of homeostatic process GO:0032844 101 0.013
Human Mouse
regulation of protein localization GO:0032880 81 0.013
response to transition metal nanoparticle GO:1990267 122 0.012
blood circulation GO:0008015 183 0.012
response to glucose GO:0009749 136 0.012
Human Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.012
cell cycle GO:0007049 101 0.012
Human
cell migration GO:0016477 197 0.012
regulation of blood circulation GO:1903522 110 0.012
defense response GO:0006952 194 0.012
negative regulation of molecular function GO:0044092 133 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
positive regulation of response to external stimulus GO:0032103 51 0.012
retinal ganglion cell axon guidance GO:0031290 1 0.012
response to axon injury GO:0048678 59 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
meiotic cell cycle process GO:1903046 3 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of protein modification process GO:0031399 194 0.012
cellular cation homeostasis GO:0030003 180 0.012
axon guidance GO:0007411 24 0.012
regulation of actin filament based process GO:0032970 42 0.012
sexual reproduction GO:0019953 148 0.012
cellular response to external stimulus GO:0071496 118 0.012
response to decreased oxygen levels GO:0036293 237 0.012
lipid metabolic process GO:0006629 283 0.012
camp biosynthetic process GO:0006171 47 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
locomotory exploration behavior GO:0035641 1 0.011
sensory perception of pain GO:0019233 73 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
potassium ion transmembrane transport GO:0071805 71 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
response to extracellular stimulus GO:0009991 380 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
single organism cellular localization GO:1902580 102 0.011
response to bacterium GO:0009617 200 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.011
response to ionizing radiation GO:0010212 59 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
circadian regulation of gene expression GO:0032922 3 0.011
response to carbohydrate GO:0009743 183 0.011
Human Mouse
neuron apoptotic process GO:0051402 88 0.011
glucose homeostasis GO:0042593 75 0.011
Human Mouse
behavior GO:0007610 205 0.011
cellular response to lipid GO:0071396 201 0.011
inflammatory response GO:0006954 150 0.011
lipid localization GO:0010876 62 0.011
response to ketone GO:1901654 182 0.011
response to food GO:0032094 27 0.011
response to cytokine GO:0034097 215 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.010
membrane organization GO:0061024 94 0.010
single organism organelle organization GO:1902589 180 0.010
Human
cell cell signaling GO:0007267 335 0.010
Human Mouse Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
embryonic pattern specification GO:0009880 1 0.010
regulation of transmembrane transporter activity GO:0022898 49 0.010
cell cycle process GO:0022402 57 0.010
Human
purine containing compound biosynthetic process GO:0072522 85 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
chromosome segregation GO:0007059 2 0.010

Brsk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.031
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
eye and adnexa disease DOID:1492 0 0.013
retinal disease DOID:5679 0 0.012
eye disease DOID:5614 0 0.012
musculoskeletal system disease DOID:17 0 0.012