Rattus norvegicus

39 known processes

Brsk1

BR serine/threonine kinase 1

(Aliases: Sad-b,RGD1563268)

Brsk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron development GO:0048666 286 0.184
neuron differentiation GO:0030182 368 0.178
neuron projection development GO:0031175 273 0.148
anatomical structure morphogenesis GO:0009653 298 0.110
cell cycle GO:0007049 101 0.104
Human
cellular component morphogenesis GO:0032989 155 0.098
cell projection organization GO:0030030 302 0.090
cell projection morphogenesis GO:0048858 123 0.083
reproduction GO:0000003 245 0.076
regulation of cellular component organization GO:0051128 368 0.076
regulation of neuron differentiation GO:0045664 208 0.074
cellular component assembly GO:0022607 360 0.074
neuron projection morphogenesis GO:0048812 122 0.074
regulation of cell development GO:0060284 263 0.070
regulation of multicellular organismal development GO:2000026 376 0.066
macromolecular complex subunit organization GO:0043933 339 0.063
synaptic transmission GO:0007268 235 0.063
cell part morphogenesis GO:0032990 123 0.062
organelle organization GO:0006996 266 0.062
negative regulation of multicellular organismal process GO:0051241 203 0.060
protein complex subunit organization GO:0071822 302 0.058
programmed cell death GO:0012501 392 0.057
positive regulation of multicellular organismal process GO:0051240 387 0.057
cell morphogenesis involved in differentiation GO:0000904 119 0.057
cellular component biogenesis GO:0044085 368 0.056
reproductive process GO:0022414 372 0.055
regulation of cell differentiation GO:0045595 320 0.055
protein phosphorylation GO:0006468 345 0.054
multi organism reproductive process GO:0044703 262 0.053
single organism organelle organization GO:1902589 180 0.052
regulation of neurogenesis GO:0050767 247 0.050
regulation of nervous system development GO:0051960 264 0.050
protein complex assembly GO:0006461 263 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.049
Fly
cell morphogenesis GO:0000902 142 0.048
positive regulation of cell communication GO:0010647 271 0.046
protein oligomerization GO:0051259 191 0.045
locomotion GO:0040011 237 0.045
chemosensory behavior GO:0007635 2 0.044
protein complex biogenesis GO:0070271 263 0.042
transcription dna templated GO:0006351 377 0.041
multicellular organismal reproductive process GO:0048609 233 0.041
regulation of programmed cell death GO:0043067 341 0.039
growth GO:0040007 165 0.039
apoptotic process GO:0006915 381 0.039
response to insulin GO:0032868 133 0.039
axon development GO:0061564 96 0.039
cell cycle process GO:0022402 57 0.039
Human
nucleotide metabolic process GO:0009117 279 0.038
tissue development GO:0009888 252 0.038
single organism reproductive process GO:0044702 297 0.038
negative regulation of metabolic process GO:0009892 331 0.037
response to oxygen levels GO:0070482 265 0.036
positive regulation of developmental process GO:0051094 283 0.036
cytoskeleton dependent cytokinesis GO:0061640 2 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
negative regulation of signaling GO:0023057 157 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
purine containing compound metabolic process GO:0072521 253 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
developmental process involved in reproduction GO:0003006 159 0.032
multicellular organism reproduction GO:0032504 233 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.032
response to hypoxia GO:0001666 231 0.032
organic substance catabolic process GO:1901575 316 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
embryonic pattern specification GO:0009880 1 0.031
positive regulation of cell development GO:0010720 176 0.031
anatomical structure formation involved in morphogenesis GO:0048646 83 0.031
regulation of signal transduction GO:0009966 318 0.030
rna metabolic process GO:0016070 406 0.030
epithelium development GO:0060429 96 0.029
cell cell signaling GO:0007267 335 0.028
cellular component movement GO:0006928 248 0.028
response to decreased oxygen levels GO:0036293 237 0.028
regulation of transcription dna templated GO:0006355 374 0.028
sexual reproduction GO:0019953 148 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
regulation of apoptotic process GO:0042981 335 0.027
positive regulation of nervous system development GO:0051962 178 0.027
regulation of protein metabolic process GO:0051246 289 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
head development GO:0060322 247 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
regeneration GO:0031099 163 0.025
axis specification GO:0009798 4 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
regulation of cell projection organization GO:0031344 175 0.025
intracellular signal transduction GO:0035556 314 0.025
brain development GO:0007420 247 0.025
limb morphogenesis GO:0035108 4 0.025
organophosphate metabolic process GO:0019637 370 0.024
single organism catabolic process GO:0044712 283 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
developmental growth GO:0048589 100 0.024
circulatory system development GO:0072359 134 0.024
cellular catabolic process GO:0044248 295 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.023
transmembrane transport GO:0055085 412 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of neuron projection development GO:0010975 161 0.023
behavior GO:0007610 205 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
olfactory behavior GO:0042048 2 0.022
heart morphogenesis GO:0003007 3 0.022
response to nutrient levels GO:0031667 370 0.022
organic acid metabolic process GO:0006082 292 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
gamete generation GO:0007276 124 0.022
macromolecular complex assembly GO:0065003 273 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
regulation of rna metabolic process GO:0051252 391 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
protein localization GO:0008104 191 0.021
feeding behavior GO:0007631 53 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
response to peptide GO:1901652 292 0.021
regulation of catalytic activity GO:0050790 304 0.021
regulation of proteasomal protein catabolic process GO:0061136 4 0.020
negative regulation of cell communication GO:0010648 158 0.020
response to peptide hormone GO:0043434 278 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
anterior posterior pattern specification GO:0009952 1 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
regulation of neuron death GO:1901214 115 0.020
positive regulation of signal transduction GO:0009967 175 0.020
regulation of molecular function GO:0065009 398 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
negative regulation of cell development GO:0010721 82 0.019
meiotic cell cycle process GO:1903046 3 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
spermatogenesis GO:0007283 99 0.019
central nervous system development GO:0007417 311 0.019
axonogenesis GO:0007409 71 0.019
response to temperature stimulus GO:0009266 94 0.019
regulation of cell growth GO:0001558 85 0.019
amine metabolic process GO:0009308 38 0.019
reproductive system development GO:0061458 128 0.019
neurological system process GO:0050877 219 0.019
response to inorganic substance GO:0010035 377 0.018
regulation of growth GO:0040008 105 0.018
cell growth GO:0016049 104 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
positive regulation of cell death GO:0010942 184 0.018
cell type specific apoptotic process GO:0097285 134 0.018
secretion GO:0046903 307 0.018
cell motility GO:0048870 202 0.018
embryonic axis specification GO:0000578 1 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
response to monosaccharide GO:0034284 159 0.018
cytoskeleton organization GO:0007010 111 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of signaling GO:0023056 270 0.018
cell migration GO:0016477 197 0.018
rhythmic process GO:0048511 156 0.018
rna biosynthetic process GO:0032774 380 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regulation of synaptic transmission GO:0050804 141 0.017
single organism behavior GO:0044708 130 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
positive regulation of gene expression GO:0010628 244 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
regulation of synaptic plasticity GO:0048167 70 0.017
establishment of protein localization GO:0045184 141 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
aromatic compound catabolic process GO:0019439 168 0.017
appendage morphogenesis GO:0035107 4 0.017
ribonucleotide catabolic process GO:0009261 136 0.016
localization of cell GO:0051674 202 0.016
positive regulation of transport GO:0051050 245 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
ras protein signal transduction GO:0007265 29 0.016
tube development GO:0035295 89 0.016
heterocycle catabolic process GO:0046700 167 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
gonad development GO:0008406 104 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
response to metal ion GO:0010038 253 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
regulation of secretion by cell GO:1903530 208 0.016
catabolic process GO:0009056 351 0.016
macromolecule localization GO:0033036 252 0.016
response to growth factor GO:0070848 189 0.016
dendrite morphogenesis GO:0048813 43 0.015
nucleoside metabolic process GO:0009116 179 0.015
signal release GO:0023061 145 0.015
regulation of hormone levels GO:0010817 187 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
embryonic skeletal system development GO:0048706 3 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
oxoacid metabolic process GO:0043436 290 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
reproductive structure development GO:0048608 128 0.015
homeostatic process GO:0042592 331 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
male gamete generation GO:0048232 99 0.015
response to nutrient GO:0007584 248 0.015
olfactory learning GO:0008355 1 0.015
cognition GO:0050890 92 0.014
chemical homeostasis GO:0048878 292 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of neuronal synaptic plasticity GO:0048168 31 0.014
protein tetramerization GO:0051262 38 0.014
neuromuscular process GO:0050905 2 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
response to extracellular stimulus GO:0009991 380 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
mitotic cell cycle GO:0000278 49 0.014
single organism biosynthetic process GO:0044711 342 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
carbohydrate homeostasis GO:0033500 75 0.014
negative regulation of nervous system development GO:0051961 79 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cell cell junction organization GO:0045216 20 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of cellular localization GO:0060341 263 0.013
embryo development GO:0009790 49 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
cytoplasmic transport GO:0016482 115 0.013
defecation GO:0030421 1 0.013
negative regulation of signal transduction GO:0009968 83 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of cell projection organization GO:0031346 111 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
positive regulation of molecular function GO:0044093 230 0.012
eye morphogenesis GO:0048592 4 0.012
neuron death GO:0070997 127 0.012
regulation of dendrite development GO:0050773 59 0.012
cellular amine metabolic process GO:0044106 38 0.012
nucleic acid templated transcription GO:0097659 379 0.012
response to wounding GO:0009611 254 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
regulation of cell migration GO:0030334 128 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
rna localization GO:0006403 4 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
response to glucose GO:0009749 136 0.012
cation transport GO:0006812 382 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
organ morphogenesis GO:0009887 75 0.012
intracellular transport GO:0046907 185 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
proteolysis GO:0006508 175 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
Fly
regulation of protein phosphorylation GO:0001932 183 0.012
circulatory system process GO:0003013 183 0.012
heart development GO:0007507 72 0.012
purine containing compound catabolic process GO:0072523 138 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of anatomical structure size GO:0090066 135 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular macromolecule localization GO:0070727 122 0.011
negative regulation of transport GO:0051051 136 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of cell cycle GO:0051726 73 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of phosphorylation GO:0042325 248 0.011
response to camp GO:0051591 91 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
organophosphate catabolic process GO:0046434 148 0.011
membrane organization GO:0061024 94 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of peptide transport GO:0090087 87 0.011
aging GO:0007568 241 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
regulation of synapse maturation GO:0090128 2 0.011
cardiovascular system development GO:0072358 134 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
cellular ketone metabolic process GO:0042180 51 0.011
negative regulation of molecular function GO:0044092 133 0.011
dna metabolic process GO:0006259 96 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.010
dendrite development GO:0016358 72 0.010
regulation of system process GO:0044057 208 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
salivary gland morphogenesis GO:0007435 1 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
actin cytoskeleton organization GO:0030036 73 0.010
muscle structure development GO:0061061 87 0.010
response to activity GO:0014823 73 0.010
neuron apoptotic process GO:0051402 88 0.010
hormone transport GO:0009914 121 0.010
cellular response to peptide GO:1901653 133 0.010
learning or memory GO:0007611 90 0.010
regulation of transmembrane transport GO:0034762 122 0.010
response to acid chemical GO:0001101 222 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
regulation of blood circulation GO:1903522 110 0.010

Brsk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012