Rattus norvegicus

20 known processes

Notch2

Notch homolog 2 (Drosophila)

Notch2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.515
Mouse Rat
cell motility GO:0048870 202 0.352
Fly
intracellular signal transduction GO:0035556 314 0.320
Human Fly
regulation of phosphate metabolic process GO:0019220 349 0.270
localization of cell GO:0051674 202 0.263
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.260
Rat Fly
regulation of cell proliferation GO:0042127 359 0.250
Human Mouse Rat Fly
mesenchymal cell proliferation GO:0010463 4 0.247
macromolecule localization GO:0033036 252 0.224
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.222
regulation of protein metabolic process GO:0051246 289 0.214
neuron differentiation GO:0030182 368 0.211
Rat Fly
transmembrane transport GO:0055085 412 0.201
programmed cell death GO:0012501 392 0.198
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.196
Rat Fly
regeneration GO:0031099 163 0.191
rhythmic process GO:0048511 156 0.186
positive regulation of developmental process GO:0051094 283 0.175
Mouse Rat
positive regulation of signaling GO:0023056 270 0.167
Human Mouse Fly
positive regulation of phosphorylation GO:0042327 177 0.159
response to wounding GO:0009611 254 0.156
positive regulation of locomotion GO:0040017 102 0.153
signal transduction by phosphorylation GO:0023014 144 0.150
regulation of cell differentiation GO:0045595 320 0.149
Mouse Rat Fly
regulation of mesenchymal cell proliferation GO:0010464 4 0.148
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.147
developmental growth GO:0048589 100 0.145
positive regulation of phosphorus metabolic process GO:0010562 262 0.143
regulation of programmed cell death GO:0043067 341 0.140
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.140
secretion GO:0046903 307 0.140
Mouse
single organism reproductive process GO:0044702 297 0.138
Mouse Rat Fly
regulation of cellular protein metabolic process GO:0032268 267 0.136
cellular component assembly GO:0022607 360 0.133
Fly
positive regulation of intracellular signal transduction GO:1902533 138 0.132
Human
regulation of phosphorylation GO:0042325 248 0.130
cell projection organization GO:0030030 302 0.129
Fly
reproductive process GO:0022414 372 0.129
Mouse Rat Fly
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.128
Rat Fly
regulation of molecular function GO:0065009 398 0.128
regulation of multicellular organismal development GO:2000026 376 0.127
Mouse Rat Fly
regulation of cell development GO:0060284 263 0.124
Rat Fly
cellular response to growth factor stimulus GO:0071363 162 0.123
regulation of intracellular signal transduction GO:1902531 218 0.123
Human
protein phosphorylation GO:0006468 345 0.122
Fly
inflammatory response GO:0006954 150 0.122
Mouse
protein transport GO:0015031 132 0.118
Mouse
macromolecular complex subunit organization GO:0043933 339 0.116
Fly
reproduction GO:0000003 245 0.115
Rat Fly
ion homeostasis GO:0050801 212 0.114
positive regulation of protein phosphorylation GO:0001934 135 0.112
positive regulation of cell communication GO:0010647 271 0.112
Human Mouse Fly
urogenital system development GO:0001655 78 0.112
Mouse Fly
positive regulation of protein metabolic process GO:0051247 178 0.112
organophosphate metabolic process GO:0019637 370 0.111
ion transmembrane transport GO:0034220 365 0.111
cellular response to endogenous stimulus GO:0071495 377 0.111
homeostatic process GO:0042592 331 0.111
Fly
cellular component morphogenesis GO:0032989 155 0.109
Fly
cellular response to hormone stimulus GO:0032870 247 0.106
regulation of nervous system development GO:0051960 264 0.106
Rat Fly
response to growth factor GO:0070848 189 0.106
positive regulation of cell proliferation GO:0008284 249 0.104
Mouse Rat Fly
immune system process GO:0002376 204 0.103
Mouse Fly
regulation of cellular component movement GO:0051270 150 0.103
multicellular organismal reproductive process GO:0048609 233 0.102
Rat Fly
regulation of catalytic activity GO:0050790 304 0.101
positive regulation of signal transduction GO:0009967 175 0.101
Human Mouse Fly
cellular response to nitrogen compound GO:1901699 210 0.101
blood vessel morphogenesis GO:0048514 58 0.099
Mouse
cell adhesion GO:0007155 110 0.098
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.098
Rat Fly
response to peptide hormone GO:0043434 278 0.098
multi organism reproductive process GO:0044703 262 0.098
Rat Fly
regulation of signal transduction GO:0009966 318 0.098
Human Mouse Fly
cellular response to organonitrogen compound GO:0071417 197 0.096
catabolic process GO:0009056 351 0.096
secretion by cell GO:0032940 248 0.090
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.089
Rat Fly
growth GO:0040007 165 0.088
establishment of protein localization GO:0045184 141 0.088
Mouse
regulation of mapk cascade GO:0043408 116 0.087
cell morphogenesis involved in differentiation GO:0000904 119 0.086
Fly
amine metabolic process GO:0009308 38 0.085
blood circulation GO:0008015 183 0.084
regulation of anatomical structure morphogenesis GO:0022603 141 0.084
Rat Fly
cellular response to organic cyclic compound GO:0071407 202 0.083
positive regulation of catalytic activity GO:0043085 184 0.082
organonitrogen compound biosynthetic process GO:1901566 167 0.082
regulation of secretion GO:0051046 224 0.081
circulatory system process GO:0003013 183 0.080
response to lipopolysaccharide GO:0032496 191 0.079
Rat
chemical homeostasis GO:0048878 292 0.077
leukocyte activation GO:0045321 76 0.077
Mouse
regulation of growth GO:0040008 105 0.077
Fly
positive regulation of cell differentiation GO:0045597 217 0.077
Mouse Rat
positive regulation of molecular function GO:0044093 230 0.076
wound healing GO:0042060 122 0.076
positive regulation of immune system process GO:0002684 90 0.075
Mouse
regulation of stem cell proliferation GO:0072091 14 0.075
Rat
sex differentiation GO:0007548 113 0.075
Fly
positive regulation of response to stimulus GO:0048584 285 0.074
Human Mouse Fly
vasculogenesis GO:0001570 3 0.074
innate immune response GO:0045087 35 0.073
negative regulation of metabolic process GO:0009892 331 0.073
Mouse Fly
gland development GO:0048732 155 0.072
Zebrafish Fly
response to hydrogen peroxide GO:0042542 89 0.072
regulation of system process GO:0044057 208 0.070
response to peptide GO:1901652 292 0.070
cellular response to insulin stimulus GO:0032869 81 0.070
cellular response to peptide hormone stimulus GO:0071375 120 0.069
positive regulation of cellular protein metabolic process GO:0032270 167 0.069
protein complex biogenesis GO:0070271 263 0.068
formation of primary germ layer GO:0001704 1 0.068
organic substance catabolic process GO:1901575 316 0.068
mapk cascade GO:0000165 140 0.067
purine nucleoside triphosphate catabolic process GO:0009146 122 0.067
response to hexose GO:0009746 144 0.067
salivary gland development GO:0007431 3 0.067
response to oxygen levels GO:0070482 265 0.067
response to monosaccharide GO:0034284 159 0.066
purine ribonucleotide metabolic process GO:0009150 227 0.066
regulation of cellular localization GO:0060341 263 0.066
cell projection morphogenesis GO:0048858 123 0.065
Fly
nucleoside phosphate metabolic process GO:0006753 283 0.065
regulation of protein phosphorylation GO:0001932 183 0.064
single organism biosynthetic process GO:0044711 342 0.063
cellular amino acid metabolic process GO:0006520 107 0.063
protein autophosphorylation GO:0046777 66 0.063
cell migration GO:0016477 197 0.063
Fly
muscle cell proliferation GO:0033002 84 0.063
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.063
Rat Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.062
response to molecule of bacterial origin GO:0002237 194 0.062
Rat
organophosphate biosynthetic process GO:0090407 143 0.062
purine ribonucleoside metabolic process GO:0046128 168 0.062
regulation of protein modification process GO:0031399 194 0.062
negative regulation of cell proliferation GO:0008285 119 0.061
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.061
Mouse Fly
neuron development GO:0048666 286 0.060
Fly
positive regulation of cell death GO:0010942 184 0.060
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.060
positive regulation of map kinase activity GO:0043406 46 0.060
tissue development GO:0009888 252 0.060
positive regulation of mapk cascade GO:0043410 92 0.059
ovulation cycle GO:0042698 67 0.059
locomotion GO:0040011 237 0.058
Fly
lipid metabolic process GO:0006629 283 0.058
purine nucleotide metabolic process GO:0006163 229 0.058
regulation of developmental growth GO:0048638 45 0.058
reproductive system development GO:0061458 128 0.057
Mouse Fly
nucleoside metabolic process GO:0009116 179 0.057
gliogenesis GO:0042063 93 0.057
Rat Fly
transcription dna templated GO:0006351 377 0.056
Mouse Rat Fly
female gonad development GO:0008585 53 0.056
response to external biotic stimulus GO:0043207 221 0.056
Mouse Rat Fly
positive regulation of gene expression GO:0010628 244 0.056
Rat Fly
negative regulation of biosynthetic process GO:0009890 168 0.055
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.055
regulation of immune system process GO:0002682 123 0.055
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.055
regulation of locomotion GO:0040012 148 0.055
regulation of apoptotic process GO:0042981 335 0.055
Mouse
organic hydroxy compound metabolic process GO:1901615 115 0.055
mesoderm development GO:0007498 2 0.054
Fly
positive regulation of transcription dna templated GO:0045893 197 0.054
Rat Fly
cellular amine metabolic process GO:0044106 38 0.053
multicellular organism growth GO:0035264 1 0.053
cellular component biogenesis GO:0044085 368 0.053
Fly
response to glucose GO:0009749 136 0.053
regulation of behavior GO:0050795 61 0.053
negative regulation of cellular metabolic process GO:0031324 281 0.052
Mouse
cellular catabolic process GO:0044248 295 0.052
blood vessel development GO:0001568 69 0.052
Mouse
regulation of body fluid levels GO:0050878 90 0.052
cell type specific apoptotic process GO:0097285 134 0.052
cell part morphogenesis GO:0032990 123 0.052
Fly
regulation of anatomical structure size GO:0090066 135 0.052
response to corticosteroid GO:0031960 235 0.051
Rat
cellular chemical homeostasis GO:0055082 247 0.051
purine containing compound metabolic process GO:0072521 253 0.051
regulation of ossification GO:0030278 32 0.051
negative regulation of osteoblast differentiation GO:0045668 2 0.051
aging GO:0007568 241 0.051
Fly
development of primary sexual characteristics GO:0045137 107 0.051
developmental process involved in reproduction GO:0003006 159 0.050
Mouse Fly
tissue regeneration GO:0042246 36 0.049
protein localization GO:0008104 191 0.049
Mouse
positive regulation of cell development GO:0010720 176 0.049
Rat
response to estrogen GO:0043627 232 0.049
nucleic acid templated transcription GO:0097659 379 0.049
Mouse Rat Fly
organelle organization GO:0006996 266 0.049
Fly
cellular response to peptide GO:1901653 133 0.049
negative regulation of multicellular organismal process GO:0051241 203 0.049
Rat Fly
response to decreased oxygen levels GO:0036293 237 0.048
regulation of organ growth GO:0046620 13 0.048
positive regulation of transport GO:0051050 245 0.048
protein complex subunit organization GO:0071822 302 0.048
Fly
cell cell signaling GO:0007267 335 0.048
Fly
positive regulation of growth GO:0045927 55 0.048
neuron projection development GO:0031175 273 0.048
Fly
behavior GO:0007610 205 0.048
Fly
cell cycle GO:0007049 101 0.048
Human Fly
oxoacid metabolic process GO:0043436 290 0.048
organ formation GO:0048645 3 0.048
Rat Fly
cellular homeostasis GO:0019725 252 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
regulation of cell motility GO:2000145 131 0.047
enzyme linked receptor protein signaling pathway GO:0007167 116 0.047
Mouse
immune response GO:0006955 104 0.047
Mouse
multicellular organismal signaling GO:0035637 44 0.047
cell growth GO:0016049 104 0.047
Human
small gtpase mediated signal transduction GO:0007264 36 0.047
Human
regulation of homeostatic process GO:0032844 101 0.046
regulation of response to wounding GO:1903034 69 0.046
single organism catabolic process GO:0044712 283 0.046
response to toxic substance GO:0009636 133 0.046
gonad development GO:0008406 104 0.046
regulation of neuron death GO:1901214 115 0.046
cellular component movement GO:0006928 248 0.045
Fly
positive regulation of cell motility GO:2000147 97 0.045
action potential GO:0001508 54 0.045
cellular protein localization GO:0034613 122 0.045
defense response GO:0006952 194 0.045
Mouse
regulation of defense response GO:0031347 68 0.045
cellular nitrogen compound catabolic process GO:0044270 163 0.045
gastrulation GO:0007369 2 0.045
regulation of hydrolase activity GO:0051336 143 0.045
kidney development GO:0001822 67 0.045
Mouse
regulation of neurogenesis GO:0050767 247 0.044
Rat Fly
glycerolipid metabolic process GO:0046486 67 0.044
negative regulation of cell death GO:0060548 229 0.044
smooth muscle cell proliferation GO:0048659 77 0.044
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.044
apoptotic process GO:0006915 381 0.044
Mouse
ovulation cycle process GO:0022602 50 0.044
regulation of protein kinase activity GO:0045859 105 0.043
striated muscle cell proliferation GO:0014855 9 0.043
response to oxidative stress GO:0006979 186 0.043
peptidyl tyrosine modification GO:0018212 72 0.043
development of primary female sexual characteristics GO:0046545 56 0.043
positive regulation of protein modification process GO:0031401 142 0.043
response to ketone GO:1901654 182 0.043
positive regulation of protein kinase activity GO:0045860 73 0.043
calcium ion transport GO:0006816 131 0.042
metal ion transport GO:0030001 289 0.042
muscle structure development GO:0061061 87 0.042
Fly
positive regulation of kinase activity GO:0033674 77 0.042
single organism organelle organization GO:1902589 180 0.042
Fly
organophosphate catabolic process GO:0046434 148 0.042
purine ribonucleotide catabolic process GO:0009154 136 0.041
response to hypoxia GO:0001666 231 0.041
regulation of response to stress GO:0080134 126 0.041
organic cyclic compound catabolic process GO:1901361 175 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.041
cation transport GO:0006812 382 0.041
ribonucleotide metabolic process GO:0009259 231 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.041
positive regulation of cell migration GO:0030335 96 0.041
cell activation GO:0001775 97 0.041
Mouse
response to mechanical stimulus GO:0009612 134 0.041
erk1 and erk2 cascade GO:0070371 48 0.040
sexual reproduction GO:0019953 148 0.040
Rat Fly
cell morphogenesis GO:0000902 142 0.040
Fly
cellular cation homeostasis GO:0030003 180 0.039
regulation of neuron differentiation GO:0045664 208 0.039
Rat Fly
purine nucleoside metabolic process GO:0042278 169 0.039
ossification GO:0001503 70 0.039
negative regulation of organ growth GO:0046621 3 0.038
brain development GO:0007420 247 0.038
Rat
negative regulation of programmed cell death GO:0043069 183 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
Human Zebrafish Mouse Rat Fly
nucleoside phosphate catabolic process GO:1901292 140 0.038
protein heterooligomerization GO:0051291 89 0.038
inorganic cation transmembrane transport GO:0098662 202 0.037
peptidyl tyrosine phosphorylation GO:0018108 72 0.037
metal ion homeostasis GO:0055065 186 0.037
protein complex assembly GO:0006461 263 0.037
nucleotide metabolic process GO:0009117 279 0.037
regulation of cell migration GO:0030334 128 0.037
salivary gland morphogenesis GO:0007435 1 0.037
positive regulation of defense response GO:0031349 37 0.037
cation homeostasis GO:0055080 195 0.037
regulation of transferase activity GO:0051338 123 0.037
embryonic skeletal system morphogenesis GO:0048704 3 0.037
response to reactive oxygen species GO:0000302 120 0.036
regulation of cell morphogenesis GO:0022604 77 0.036
ribose phosphate metabolic process GO:0019693 235 0.036
muscle tissue development GO:0060537 58 0.036
Fly
response to inorganic substance GO:0010035 377 0.036
glycosyl compound metabolic process GO:1901657 182 0.036
regulation of ion transport GO:0043269 245 0.036
monovalent inorganic cation transport GO:0015672 172 0.036
organic acid metabolic process GO:0006082 292 0.036
positive regulation of nervous system development GO:0051962 178 0.035
Rat
protein oligomerization GO:0051259 191 0.035
cellular lipid metabolic process GO:0044255 208 0.035
negative regulation of immune system process GO:0002683 39 0.035
biological adhesion GO:0022610 110 0.035
Fly
female pregnancy GO:0007565 122 0.035
response to extracellular stimulus GO:0009991 380 0.035
regulation of map kinase activity GO:0043405 53 0.035
activation of protein kinase activity GO:0032147 47 0.035
positive regulation of secretion GO:0051047 140 0.034
anatomical structure formation involved in morphogenesis GO:0048646 83 0.034
Mouse Rat Fly
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
Rat Fly
heterocycle catabolic process GO:0046700 167 0.034
regulation of establishment of protein localization GO:0070201 69 0.034
embryonic skeletal system development GO:0048706 3 0.034
proteolysis GO:0006508 175 0.034
ribonucleotide catabolic process GO:0009261 136 0.034
purine nucleotide catabolic process GO:0006195 136 0.034
neuronal action potential GO:0019228 35 0.034
regulation of metal ion transport GO:0010959 118 0.034
negative regulation of signaling GO:0023057 157 0.033
positive regulation of nucleotide metabolic process GO:0045981 91 0.033
single organism intracellular transport GO:1902582 166 0.033
synaptic transmission GO:0007268 235 0.033
negative regulation of cell communication GO:0010648 158 0.033
positive regulation of cellular component movement GO:0051272 102 0.033
cellular divalent inorganic cation homeostasis GO:0072503 162 0.032
protein homooligomerization GO:0051260 91 0.032
carbohydrate metabolic process GO:0005975 130 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.032
regulation of membrane potential GO:0042391 110 0.032
glial cell differentiation GO:0010001 65 0.032
Rat Fly
hepaticobiliary system development GO:0061008 90 0.032
Zebrafish
central nervous system development GO:0007417 311 0.031
Rat
negative regulation of apoptotic process GO:0043066 181 0.031
ras protein signal transduction GO:0007265 29 0.031
Human
cation transmembrane transport GO:0098655 263 0.031
cellular metal ion homeostasis GO:0006875 172 0.031
regulation of secretion by cell GO:1903530 208 0.031
regulation of cell projection organization GO:0031344 175 0.031
Fly
regulation of response to external stimulus GO:0032101 106 0.031
response to nutrient levels GO:0031667 370 0.031
response to estradiol GO:0032355 164 0.031
cellular response to corticosteroid stimulus GO:0071384 69 0.031
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.031
mesoderm morphogenesis GO:0048332 1 0.030
cell cycle process GO:0022402 57 0.030
Human Fly
carboxylic acid metabolic process GO:0019752 289 0.030
single organism cellular localization GO:1902580 102 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.030
regulation of blood vessel size GO:0050880 89 0.030
muscle contraction GO:0006936 88 0.030
intracellular transport GO:0046907 185 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
neuron death GO:0070997 127 0.029
transmission of nerve impulse GO:0019226 42 0.029
regulation of catabolic process GO:0009894 113 0.029
inorganic ion transmembrane transport GO:0098660 229 0.029
cellular ion homeostasis GO:0006873 184 0.029
regulation of protein transport GO:0051223 68 0.028
multicellular organism reproduction GO:0032504 233 0.028
Rat Fly
macromolecular complex assembly GO:0065003 273 0.028
mesoderm formation GO:0001707 1 0.028
epithelium development GO:0060429 96 0.028
Mouse Rat Fly
regulation of heart growth GO:0060420 12 0.028
vascular process in circulatory system GO:0003018 96 0.028
taxis GO:0042330 67 0.028
Fly
single organism behavior GO:0044708 130 0.028
Fly
female sex differentiation GO:0046660 59 0.028
positive regulation of programmed cell death GO:0043068 157 0.028
Mouse
purine containing compound catabolic process GO:0072523 138 0.027
synapse organization GO:0050808 46 0.027
regulation of smooth muscle cell proliferation GO:0048660 75 0.027
lymphocyte activation GO:0046649 43 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.027
Mouse
neuron projection morphogenesis GO:0048812 122 0.027
Fly
vesicle mediated transport GO:0016192 181 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
Rat Fly
head development GO:0060322 247 0.027
Zebrafish Rat
organ morphogenesis GO:0009887 75 0.026
Human Zebrafish Mouse Rat Fly
response to carbohydrate GO:0009743 183 0.026
eye morphogenesis GO:0048592 4 0.026
Mouse Fly
cell junction organization GO:0034330 21 0.026
rna biosynthetic process GO:0032774 380 0.026
Mouse Rat Fly
regulation of neuron projection development GO:0010975 161 0.026
multi multicellular organism process GO:0044706 138 0.026
liver development GO:0001889 90 0.026
Zebrafish
purine ribonucleoside catabolic process GO:0046130 124 0.026
response to glucocorticoid GO:0051384 223 0.026
b cell differentiation GO:0030183 2 0.026
regulation of dna metabolic process GO:0051052 60 0.026
immune system development GO:0002520 41 0.026
Mouse Fly
regulation of protein serine threonine kinase activity GO:0071900 64 0.025
guanosine containing compound metabolic process GO:1901068 74 0.025
purine nucleoside triphosphate metabolic process GO:0009144 141 0.025
regulation of cellular component organization GO:0051128 368 0.025
Fly
appendage morphogenesis GO:0035107 4 0.025
Mouse Fly
response to insulin GO:0032868 133 0.025
ribonucleoside triphosphate catabolic process GO:0009203 122 0.024
divalent inorganic cation transport GO:0072511 134 0.024
purine nucleoside catabolic process GO:0006152 124 0.024
response to biotic stimulus GO:0009607 226 0.024
Mouse Rat Fly
response to cytokine GO:0034097 215 0.024
aromatic compound catabolic process GO:0019439 168 0.024
tube development GO:0035295 89 0.024
Mouse Fly
positive regulation of transferase activity GO:0051347 81 0.024
reproductive structure development GO:0048608 128 0.024
Mouse Fly
negative regulation of response to stimulus GO:0048585 155 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
organ regeneration GO:0031100 101 0.024
Rat
negative regulation of signal transduction GO:0009968 83 0.023
peptidyl amino acid modification GO:0018193 126 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.023
cell cell junction organization GO:0045216 20 0.023
regulation of kinase activity GO:0043549 117 0.023
anterior posterior pattern specification GO:0009952 1 0.023
Fly
dna metabolic process GO:0006259 96 0.023
striated muscle tissue development GO:0014706 58 0.023
Fly
negative regulation of heart growth GO:0061117 3 0.023
neurological system process GO:0050877 219 0.023
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
peptide transport GO:0015833 97 0.023
anion transmembrane transport GO:0098656 77 0.023
hematopoietic or lymphoid organ development GO:0048534 36 0.023
Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.023
Mouse Rat Fly
cardiac muscle cell proliferation GO:0060038 6 0.023
negative regulation of developmental process GO:0051093 125 0.022
Rat Fly
actin filament based process GO:0030029 86 0.022
Fly
organonitrogen compound catabolic process GO:1901565 179 0.022
response to bacterium GO:0009617 200 0.022
Mouse Rat
heart valve morphogenesis GO:0003179 1 0.022
Human
cellular calcium ion homeostasis GO:0006874 160 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
negative regulation of nervous system development GO:0051961 79 0.022
Rat Fly
forebrain development GO:0030900 98 0.022
coronary vasculature morphogenesis GO:0060977 3 0.022
negative regulation of cardiac muscle tissue development GO:0055026 3 0.022
chemotaxis GO:0006935 66 0.022
Fly
protein targeting GO:0006605 61 0.022
muscle system process GO:0003012 115 0.022
cellular response to glucocorticoid stimulus GO:0071385 68 0.022
cellular ketone metabolic process GO:0042180 51 0.022
nucleotide catabolic process GO:0009166 139 0.022
regulation of osteoblast differentiation GO:0045667 14 0.022
kidney epithelium development GO:0072073 19 0.022
Mouse
telencephalon development GO:0021537 62 0.022
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.022
regulation of blood pressure GO:0008217 83 0.022
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.022
positive regulation of stem cell proliferation GO:2000648 13 0.022
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.021
regulation of synaptic transmission GO:0050804 141 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
response to organophosphorus GO:0046683 102 0.021
dendrite morphogenesis GO:0048813 43 0.021
gamete generation GO:0007276 124 0.021
Rat Fly
regulation of canonical wnt signaling pathway GO:0060828 4 0.021
regulation of neural precursor cell proliferation GO:2000177 16 0.021
Rat
nucleoside catabolic process GO:0009164 126 0.021
negative regulation of muscle cell apoptotic process GO:0010656 21 0.021
regulation of cardiac muscle tissue development GO:0055024 12 0.021
sensory perception GO:0007600 101 0.021
lipid transport GO:0006869 61 0.020
specification of organ identity GO:0010092 2 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
negative regulation of neuron differentiation GO:0045665 62 0.020
Rat Fly
response to alkaloid GO:0043279 132 0.020
regulation of cell growth GO:0001558 85 0.020
sodium ion transport GO:0006814 82 0.020
response to other organism GO:0051707 220 0.020
Mouse Rat Fly
neuron projection guidance GO:0097485 24 0.020
Fly
axonogenesis GO:0007409 71 0.020
Fly
regulation of muscle tissue development GO:1901861 25 0.020
negative regulation of neuron death GO:1901215 69 0.020
protein import GO:0017038 37 0.020
protein maturation GO:0051604 68 0.020
negative regulation of protein phosphorylation GO:0001933 44 0.020
mesodermal cell differentiation GO:0048333 1 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
ensheathment of neurons GO:0007272 40 0.020
hormone secretion GO:0046879 115 0.020
cardiac muscle tissue growth GO:0055017 20 0.019
single organismal cell cell adhesion GO:0016337 42 0.019
cardiovascular system development GO:0072358 134 0.019
Human Zebrafish Mouse Rat Fly
positive regulation of cell projection organization GO:0031346 111 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019

Notch2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.085
disease of anatomical entity DOID:7 0 0.085
Human
nervous system disease DOID:863 0 0.051
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.033
cancer DOID:162 0 0.033
connective tissue disease DOID:65 0 0.029
gastrointestinal system cancer DOID:3119 0 0.028
cardiovascular system disease DOID:1287 0 0.026
vascular disease DOID:178 0 0.022
bone disease DOID:0080001 0 0.020
bone development disease DOID:0080006 0 0.020