Rattus norvegicus

0 known processes

Efs

embryonal Fyn-associated substrate

Efs biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 283 0.087
cellular lipid metabolic process GO:0044255 208 0.079
nucleic acid templated transcription GO:0097659 379 0.063
positive regulation of phosphate metabolic process GO:0045937 262 0.060
rna metabolic process GO:0016070 406 0.053
intracellular signal transduction GO:0035556 314 0.050
transcription dna templated GO:0006351 377 0.044
rna biosynthetic process GO:0032774 380 0.043
regulation of rna metabolic process GO:0051252 391 0.042
regulation of cell proliferation GO:0042127 359 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.038
response to inorganic substance GO:0010035 377 0.037
regulation of canonical wnt signaling pathway GO:0060828 4 0.035
negative regulation of biosynthetic process GO:0009890 168 0.032
negative regulation of rna metabolic process GO:0051253 123 0.032
regulation of signal transduction GO:0009966 318 0.032
regulation of transcription dna templated GO:0006355 374 0.032
negative regulation of signal transduction GO:0009968 83 0.032
regulation of cell differentiation GO:0045595 320 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
negative regulation of gene expression GO:0010629 199 0.030
non canonical wnt signaling pathway GO:0035567 3 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
positive regulation of developmental process GO:0051094 283 0.028
organophosphate metabolic process GO:0019637 370 0.028
carboxylic acid metabolic process GO:0019752 289 0.027
oxoacid metabolic process GO:0043436 290 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
protein phosphorylation GO:0006468 345 0.027
negative regulation of transcription dna templated GO:0045892 116 0.026
organic acid metabolic process GO:0006082 292 0.026
regulation of stem cell differentiation GO:2000736 2 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
organophosphate biosynthetic process GO:0090407 143 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
organelle organization GO:0006996 266 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
nucleoside metabolic process GO:0009116 179 0.024
regulation of apoptotic process GO:0042981 335 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.023
mapk cascade GO:0000165 140 0.023
single organism biosynthetic process GO:0044711 342 0.023
heart morphogenesis GO:0003007 3 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
defense response GO:0006952 194 0.023
regulation of catabolic process GO:0009894 113 0.022
organic substance catabolic process GO:1901575 316 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
gland development GO:0048732 155 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
positive regulation of molecular function GO:0044093 230 0.022
salivary gland development GO:0007431 3 0.021
positive regulation of mapk cascade GO:0043410 92 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
regulation of cell development GO:0060284 263 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
localization of cell GO:0051674 202 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
apoptotic process GO:0006915 381 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.020
secretion GO:0046903 307 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
regulation of mapk cascade GO:0043408 116 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
response to external biotic stimulus GO:0043207 221 0.019
cellular catabolic process GO:0044248 295 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
cation homeostasis GO:0055080 195 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
purine containing compound metabolic process GO:0072521 253 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
response to cytokine GO:0034097 215 0.018
regulation of response to stress GO:0080134 126 0.018
salivary gland morphogenesis GO:0007435 1 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
positive regulation of protein modification process GO:0031401 142 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
small gtpase mediated signal transduction GO:0007264 36 0.017
cell projection organization GO:0030030 302 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
cellular response to external stimulus GO:0071496 118 0.017
cellular homeostasis GO:0019725 252 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
negative regulation of metabolic process GO:0009892 331 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of cell development GO:0010720 176 0.017
cellular component morphogenesis GO:0032989 155 0.017
response to metal ion GO:0010038 253 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
single organism reproductive process GO:0044702 297 0.016
muscle cell proliferation GO:0033002 84 0.016
locomotion GO:0040011 237 0.016
ras protein signal transduction GO:0007265 29 0.016
response to corticosteroid GO:0031960 235 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
cellular amine metabolic process GO:0044106 38 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
chemical homeostasis GO:0048878 292 0.016
vesicle mediated transport GO:0016192 181 0.015
response to growth factor GO:0070848 189 0.015
neuron differentiation GO:0030182 368 0.015
ion homeostasis GO:0050801 212 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
organ formation GO:0048645 3 0.015
catabolic process GO:0009056 351 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
response to biotic stimulus GO:0009607 226 0.015
response to oxidative stress GO:0006979 186 0.015
positive regulation of gene expression GO:0010628 244 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
circulatory system process GO:0003013 183 0.015
cell motility GO:0048870 202 0.015
purine containing compound catabolic process GO:0072523 138 0.015
protein complex subunit organization GO:0071822 302 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
growth GO:0040007 165 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
cell migration GO:0016477 197 0.014
aging GO:0007568 241 0.014
intracellular transport GO:0046907 185 0.014
cellular component movement GO:0006928 248 0.014
regulation of secretion GO:0051046 224 0.014
negative regulation of cell death GO:0060548 229 0.014
cation transmembrane transport GO:0098655 263 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of stem cell proliferation GO:0072091 14 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
cellular component biogenesis GO:0044085 368 0.014
response to other organism GO:0051707 220 0.014
actin filament based process GO:0030029 86 0.014
reproductive process GO:0022414 372 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
wnt signaling pathway GO:0016055 17 0.014
regulation of cellular component organization GO:0051128 368 0.014
regulation of phosphorylation GO:0042325 248 0.014
cellular component assembly GO:0022607 360 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
proteolysis GO:0006508 175 0.013
heterocycle catabolic process GO:0046700 167 0.013
lung development GO:0030324 43 0.013
regulation of neurogenesis GO:0050767 247 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cellular ketone metabolic process GO:0042180 51 0.013
cellular ion homeostasis GO:0006873 184 0.013
nucleotide metabolic process GO:0009117 279 0.013
b cell differentiation GO:0030183 2 0.013
transmembrane transport GO:0055085 412 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
secretion by cell GO:0032940 248 0.013
regulation of metanephros development GO:0072215 4 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
response to oxygen levels GO:0070482 265 0.013
ion transmembrane transport GO:0034220 365 0.013
blood circulation GO:0008015 183 0.013
neuron projection development GO:0031175 273 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
ribonucleotide catabolic process GO:0009261 136 0.012
cellular response to peptide GO:1901653 133 0.012
regulation of molecular function GO:0065009 398 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
response to hydrogen peroxide GO:0042542 89 0.012
cellular chemical homeostasis GO:0055082 247 0.012
regulation of response to external stimulus GO:0032101 106 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
regulation of secretion by cell GO:1903530 208 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
negative regulation of secretion GO:0051048 82 0.012
immune effector process GO:0002252 53 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
response to glucose GO:0009749 136 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
neural crest cell differentiation GO:0014033 2 0.012
multi organism reproductive process GO:0044703 262 0.012
protein complex assembly GO:0006461 263 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
metal ion homeostasis GO:0055065 186 0.011
cell morphogenesis GO:0000902 142 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
macromolecular complex assembly GO:0065003 273 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
protein complex biogenesis GO:0070271 263 0.011
response to peptide GO:1901652 292 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
homeostatic process GO:0042592 331 0.011
gonad development GO:0008406 104 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
small molecule biosynthetic process GO:0044283 124 0.011
respiratory system development GO:0060541 45 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of catalytic activity GO:0050790 304 0.011
skeletal system development GO:0001501 41 0.011
embryonic pattern specification GO:0009880 1 0.011
neuron development GO:0048666 286 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
positive regulation of signal transduction GO:0009967 175 0.011
reproduction GO:0000003 245 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
organ regeneration GO:0031100 101 0.011
membrane fusion GO:0061025 26 0.011
central nervous system development GO:0007417 311 0.011
regulation of programmed cell death GO:0043067 341 0.011
single organism catabolic process GO:0044712 283 0.011
nitrogen compound transport GO:0071705 229 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of hormone levels GO:0010817 187 0.011
regeneration GO:0031099 163 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
positive regulation of cell communication GO:0010647 271 0.011
membrane organization GO:0061024 94 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of protein metabolic process GO:0051246 289 0.011
negative regulation of secretion by cell GO:1903531 72 0.010
cellular response to lipid GO:0071396 201 0.010
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.010
exocytosis GO:0006887 60 0.010
response to acid chemical GO:0001101 222 0.010
protein oligomerization GO:0051259 191 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
head development GO:0060322 247 0.010
response to carbohydrate GO:0009743 183 0.010
response to hypoxia GO:0001666 231 0.010
response to estrogen GO:0043627 232 0.010
regulation of neuron death GO:1901214 115 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
sexual reproduction GO:0019953 148 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
regulation of mesenchymal cell proliferation GO:0010464 4 0.010

Efs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
gastrointestinal system disease DOID:77 0 0.028
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
nervous system disease DOID:863 0 0.011