Rattus norvegicus

0 known processes

Cdca2

cell division cycle associated 2

Cdca2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
spindle organization GO:0007051 2 0.111
regulation of proteasomal protein catabolic process GO:0061136 4 0.108
chromosome segregation GO:0007059 2 0.092
oxoacid metabolic process GO:0043436 290 0.092
reproductive process GO:0022414 372 0.087
regulation of molecular function GO:0065009 398 0.081
cellular component assembly GO:0022607 360 0.079
regulation of multicellular organismal development GO:2000026 376 0.067
regulation of cellular amine metabolic process GO:0033238 8 0.064
protein complex subunit organization GO:0071822 302 0.064
cellular component biogenesis GO:0044085 368 0.063
amine metabolic process GO:0009308 38 0.063
protein phosphorylation GO:0006468 345 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.060
organic acid metabolic process GO:0006082 292 0.059
regulation of phosphate metabolic process GO:0019220 349 0.057
cellular ketone metabolic process GO:0042180 51 0.057
regulation of phosphorus metabolic process GO:0051174 349 0.055
regulation of protein metabolic process GO:0051246 289 0.055
single organism reproductive process GO:0044702 297 0.052
regulation of chromosome segregation GO:0051983 1 0.052
positive regulation of phosphorus metabolic process GO:0010562 262 0.052
cellular amine metabolic process GO:0044106 38 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.051
regulation of programmed cell death GO:0043067 341 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.049
carboxylic acid metabolic process GO:0019752 289 0.048
cellular amino acid metabolic process GO:0006520 107 0.048
multi organism reproductive process GO:0044703 262 0.047
organic substance catabolic process GO:1901575 316 0.047
regulation of transferase activity GO:0051338 123 0.047
macromolecular complex subunit organization GO:0043933 339 0.047
protein complex assembly GO:0006461 263 0.046
multicellular organism reproduction GO:0032504 233 0.045
regulation of phosphorylation GO:0042325 248 0.045
regulation of cellular ketone metabolic process GO:0010565 27 0.044
programmed cell death GO:0012501 392 0.044
positive regulation of developmental process GO:0051094 283 0.044
organelle organization GO:0006996 266 0.044
cellular catabolic process GO:0044248 295 0.043
positive regulation of multicellular organismal process GO:0051240 387 0.042
regulation of protein phosphorylation GO:0001932 183 0.042
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
regulation of cell differentiation GO:0045595 320 0.042
developmental process involved in reproduction GO:0003006 159 0.042
mitotic sister chromatid separation GO:0051306 1 0.042
negative regulation of metabolic process GO:0009892 331 0.041
organophosphate metabolic process GO:0019637 370 0.041
reproduction GO:0000003 245 0.041
neuron differentiation GO:0030182 368 0.040
cytoskeleton organization GO:0007010 111 0.039
regulation of cellular component organization GO:0051128 368 0.039
anatomical structure morphogenesis GO:0009653 298 0.039
apoptotic process GO:0006915 381 0.038
mitotic spindle organization GO:0007052 2 0.038
regulation of signal transduction GO:0009966 318 0.037
regulation of catalytic activity GO:0050790 304 0.037
microtubule organizing center organization GO:0031023 1 0.037
regulation of cell development GO:0060284 263 0.037
centrosome cycle GO:0007098 1 0.037
positive regulation of cellular amine metabolic process GO:0033240 3 0.037
cell projection organization GO:0030030 302 0.035
cellular component morphogenesis GO:0032989 155 0.035
regulation of protein modification process GO:0031399 194 0.035
regulation of nervous system development GO:0051960 264 0.035
protein complex biogenesis GO:0070271 263 0.034
intracellular signal transduction GO:0035556 314 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
response to cytokine GO:0034097 215 0.033
central nervous system development GO:0007417 311 0.033
positive regulation of protein metabolic process GO:0051247 178 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
sister chromatid segregation GO:0000819 1 0.032
neuron development GO:0048666 286 0.032
macromolecular complex assembly GO:0065003 273 0.031
negative regulation of developmental process GO:0051093 125 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
positive regulation of protein modification process GO:0031401 142 0.030
synaptic transmission GO:0007268 235 0.030
organic cyclic compound catabolic process GO:1901361 175 0.030
positive regulation of cell development GO:0010720 176 0.029
regulation of apoptotic process GO:0042981 335 0.029
regulation of cell proliferation GO:0042127 359 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
cell cycle GO:0007049 101 0.028
regulation of rna metabolic process GO:0051252 391 0.028
anterior posterior pattern specification GO:0009952 1 0.028
purine containing compound catabolic process GO:0072523 138 0.028
regulation of neurogenesis GO:0050767 247 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.027
cellular response to stress GO:0033554 269 0.027
nucleoside metabolic process GO:0009116 179 0.027
negative regulation of molecular function GO:0044092 133 0.027
positive regulation of cellular component organization GO:0051130 200 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
single organism organelle organization GO:1902589 180 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
negative regulation of cell death GO:0060548 229 0.025
cytoskeleton dependent cytokinesis GO:0061640 2 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
catabolic process GO:0009056 351 0.024
negative regulation of cellular component organization GO:0051129 83 0.024
sexual reproduction GO:0019953 148 0.024
mitotic sister chromatid segregation GO:0000070 1 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
neuron projection development GO:0031175 273 0.024
reproductive structure development GO:0048608 128 0.023
single organism catabolic process GO:0044712 283 0.023
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
anatomical structure formation involved in morphogenesis GO:0048646 83 0.023
response to toxic substance GO:0009636 133 0.023
centrosome organization GO:0051297 1 0.023
purine containing compound metabolic process GO:0072521 253 0.022
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.022
regulation of transcription dna templated GO:0006355 374 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
negative regulation of gene expression GO:0010629 199 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
circulatory system development GO:0072359 134 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
rna metabolic process GO:0016070 406 0.022
reproductive system development GO:0061458 128 0.022
cellular component movement GO:0006928 248 0.021
ras protein signal transduction GO:0007265 29 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
positive regulation of signaling GO:0023056 270 0.021
gamete generation GO:0007276 124 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
metaphase anaphase transition of cell cycle GO:0044784 1 0.020
cellular lipid metabolic process GO:0044255 208 0.020
development of primary sexual characteristics GO:0045137 107 0.020
cellular macromolecular complex assembly GO:0034622 58 0.020
peptidyl amino acid modification GO:0018193 126 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
positive regulation of cell communication GO:0010647 271 0.020
blood circulation GO:0008015 183 0.020
response to extracellular stimulus GO:0009991 380 0.019
positive regulation of molecular function GO:0044093 230 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
aromatic compound catabolic process GO:0019439 168 0.019
negative regulation of cell cycle phase transition GO:1901988 4 0.019
nucleotide metabolic process GO:0009117 279 0.019
intracellular transport GO:0046907 185 0.019
heterocycle catabolic process GO:0046700 167 0.019
regulation of system process GO:0044057 208 0.019
cell cell signaling GO:0007267 335 0.019
proteolysis GO:0006508 175 0.019
positive regulation of nervous system development GO:0051962 178 0.018
response to wounding GO:0009611 254 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
response to corticosteroid GO:0031960 235 0.018
regulation of mitotic sister chromatid segregation GO:0033047 1 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
protein localization GO:0008104 191 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of cell cycle GO:0051726 73 0.018
brain development GO:0007420 247 0.018
reactive oxygen species metabolic process GO:0072593 37 0.018
cell morphogenesis GO:0000902 142 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
dna packaging GO:0006323 4 0.017
growth GO:0040007 165 0.017
response to oxygen levels GO:0070482 265 0.017
meiotic cell cycle process GO:1903046 3 0.017
cell part morphogenesis GO:0032990 123 0.017
response to bacterium GO:0009617 200 0.017
cytokinetic process GO:0032506 1 0.017
cellular macromolecule localization GO:0070727 122 0.017
regulation of catabolic process GO:0009894 113 0.017
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
cellular chemical homeostasis GO:0055082 247 0.017
positive regulation of gene expression GO:0010628 244 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
response to biotic stimulus GO:0009607 226 0.016
gonad development GO:0008406 104 0.016
response to glucocorticoid GO:0051384 223 0.016
response to external biotic stimulus GO:0043207 221 0.016
regulation of cell projection organization GO:0031344 175 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
cardiovascular system development GO:0072358 134 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
locomotion GO:0040011 237 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
dna integrity checkpoint GO:0031570 2 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.016
axis specification GO:0009798 4 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
mapk cascade GO:0000165 140 0.016
microtubule based process GO:0007017 36 0.015
regulation of response to stress GO:0080134 126 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
response to acid chemical GO:0001101 222 0.015
cellular protein complex assembly GO:0043623 44 0.015
regulation of organelle organization GO:0033043 80 0.015
single organism intracellular transport GO:1902582 166 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
cellular homeostasis GO:0019725 252 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
wound healing GO:0042060 122 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
head development GO:0060322 247 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
response to mechanical stimulus GO:0009612 134 0.015
response to oxidative stress GO:0006979 186 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
aging GO:0007568 241 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
response to nutrient levels GO:0031667 370 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
sex differentiation GO:0007548 113 0.014
response to decreased oxygen levels GO:0036293 237 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cell cycle checkpoint GO:0000075 2 0.014
regulation of neuron projection development GO:0010975 161 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
response to growth factor GO:0070848 189 0.014
rna biosynthetic process GO:0032774 380 0.014
regulation of membrane potential GO:0042391 110 0.014
metal ion transport GO:0030001 289 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
regulation of cellular localization GO:0060341 263 0.014
establishment of protein localization GO:0045184 141 0.014
epithelium development GO:0060429 96 0.014
regulation of kinase activity GO:0043549 117 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
regulation of reactive oxygen species metabolic process GO:2000377 26 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
cellular response to alcohol GO:0097306 87 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
modification dependent protein catabolic process GO:0019941 14 0.013
positive regulation of catabolic process GO:0009896 78 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
regulation of protein kinase activity GO:0045859 105 0.013
response to organophosphorus GO:0046683 102 0.013
ion homeostasis GO:0050801 212 0.013
cellular response to tumor necrosis factor GO:0071356 46 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
female pregnancy GO:0007565 122 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
microtubule polymerization or depolymerization GO:0031109 13 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
cytoplasmic transport GO:0016482 115 0.013
nucleotide catabolic process GO:0009166 139 0.013
regulation of synaptic transmission GO:0050804 141 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
ion transmembrane transport GO:0034220 365 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
cell growth GO:0016049 104 0.013
regulation of hydrolase activity GO:0051336 143 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
regulation of neuron differentiation GO:0045664 208 0.013
cell type specific apoptotic process GO:0097285 134 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
positive regulation of cell death GO:0010942 184 0.013
negative regulation of cell development GO:0010721 82 0.013
response to inorganic substance GO:0010035 377 0.013
negative regulation of transport GO:0051051 136 0.013
cell cycle process GO:0022402 57 0.013
cation homeostasis GO:0055080 195 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
response to hypoxia GO:0001666 231 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of mapk cascade GO:0043408 116 0.013
dna metabolic process GO:0006259 96 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.013
negative regulation of nervous system development GO:0051961 79 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
microtubule cytoskeleton organization GO:0000226 25 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
chromosome separation GO:0051304 1 0.012
response to estrogen GO:0043627 232 0.012
positive regulation of transferase activity GO:0051347 81 0.012
tissue development GO:0009888 252 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of sister chromatid segregation GO:0033045 1 0.012
negative regulation of microtubule depolymerization GO:0007026 3 0.012
response to peptide GO:1901652 292 0.012
transcription dna templated GO:0006351 377 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
single fertilization GO:0007338 3 0.012
regulation of mitotic sister chromatid separation GO:0010965 1 0.012
developmental growth GO:0048589 100 0.012
response to reactive oxygen species GO:0000302 120 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
salivary gland morphogenesis GO:0007435 1 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
membrane organization GO:0061024 94 0.012
regulation of dendrite development GO:0050773 59 0.011
dendrite development GO:0016358 72 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
defense response GO:0006952 194 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
mitotic cell cycle process GO:1903047 35 0.011
single organism cellular localization GO:1902580 102 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
transmembrane transport GO:0055085 412 0.011
response to lipopolysaccharide GO:0032496 191 0.011
negative regulation of cell communication GO:0010648 158 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
cation transport GO:0006812 382 0.011
cell projection morphogenesis GO:0048858 123 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
maintenance of location GO:0051235 17 0.011
cellular ion homeostasis GO:0006873 184 0.011
gliogenesis GO:0042063 93 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
muscle cell proliferation GO:0033002 84 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of protein catabolic process GO:0042176 16 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
rna localization GO:0006403 4 0.011
cellular response to lipid GO:0071396 201 0.011
negative regulation of signaling GO:0023057 157 0.011
nucleic acid templated transcription GO:0097659 379 0.011
response to ethanol GO:0045471 162 0.011
negative regulation of nuclear division GO:0051784 1 0.010
macromolecule catabolic process GO:0009057 58 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
circulatory system process GO:0003013 183 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
regulation of proteolysis GO:0030162 66 0.010
single organism membrane organization GO:0044802 74 0.010
regulation of growth GO:0040008 105 0.010
calcium ion transport GO:0006816 131 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
response to peptide hormone GO:0043434 278 0.010
negative regulation of cell division GO:0051782 1 0.010
negative regulation of protein maturation GO:1903318 47 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
protein maturation GO:0051604 68 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
neurological system process GO:0050877 219 0.010
response to vitamin GO:0033273 131 0.010
cellular response to external stimulus GO:0071496 118 0.010
rho protein signal transduction GO:0007266 11 0.010
protein modification by small protein conjugation or removal GO:0070647 35 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010

Cdca2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
sensory system disease DOID:0050155 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.012