Rattus norvegicus

0 known processes

Leprot

leptin receptor overlapping transcript

(Aliases: Obrgrp,Ob-Rgrp)

Leprot biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 289 0.102
regulation of multicellular organismal development GO:2000026 376 0.072
negative regulation of gene expression GO:0010629 199 0.054
positive regulation of multicellular organismal process GO:0051240 387 0.052
neuron differentiation GO:0030182 368 0.051
reproductive process GO:0022414 372 0.050
purine containing compound metabolic process GO:0072521 253 0.048
organic substance catabolic process GO:1901575 316 0.046
catabolic process GO:0009056 351 0.046
carboxylic acid metabolic process GO:0019752 289 0.045
regulation of cellular protein metabolic process GO:0032268 267 0.045
cellular catabolic process GO:0044248 295 0.044
organonitrogen compound catabolic process GO:1901565 179 0.043
nitrogen compound transport GO:0071705 229 0.042
regulation of response to stress GO:0080134 126 0.041
aromatic compound catabolic process GO:0019439 168 0.039
neuron development GO:0048666 286 0.039
regulation of corticotropin secretion GO:0051459 7 0.038
membrane fusion GO:0061025 26 0.036
cellular macromolecule localization GO:0070727 122 0.035
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
proteolysis GO:0006508 175 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
platelet derived growth factor production GO:0090360 2 0.034
positive regulation of developmental process GO:0051094 283 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
purine nucleoside metabolic process GO:0042278 169 0.032
amide transport GO:0042886 105 0.031
regulation of neuron differentiation GO:0045664 208 0.030
cellular component assembly GO:0022607 360 0.030
cytokinetic process GO:0032506 1 0.030
macromolecule localization GO:0033036 252 0.029
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
single organism reproductive process GO:0044702 297 0.028
organophosphate metabolic process GO:0019637 370 0.028
multi organism reproductive process GO:0044703 262 0.028
positive regulation of cell projection organization GO:0031346 111 0.028
single organism intracellular transport GO:1902582 166 0.028
regulation of retinal cell programmed cell death GO:0046668 1 0.027
cellular component movement GO:0006928 248 0.027
purine nucleoside triphosphate catabolic process GO:0009146 122 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
positive regulation of cell death GO:0010942 184 0.027
oxoacid metabolic process GO:0043436 290 0.027
organic acid transport GO:0015849 116 0.027
rhythmic process GO:0048511 156 0.026
negative regulation of metabolic process GO:0009892 331 0.026
hormone secretion GO:0046879 115 0.026
lipid metabolic process GO:0006629 283 0.026
regulation of secretion by cell GO:1903530 208 0.026
secretion by cell GO:0032940 248 0.026
developmental process involved in reproduction GO:0003006 159 0.026
regulation of secretion GO:0051046 224 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.025
regulation of cell proliferation GO:0042127 359 0.025
hormone transport GO:0009914 121 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
purine nucleoside triphosphate metabolic process GO:0009144 141 0.025
cellular component biogenesis GO:0044085 368 0.025
gonad development GO:0008406 104 0.025
positive regulation of retinal cell programmed cell death GO:0046670 1 0.024
negative regulation of cellular protein metabolic process GO:0032269 106 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.024
cellular protein localization GO:0034613 122 0.024
organelle fusion GO:0048284 17 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
heterocycle catabolic process GO:0046700 167 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
protein complex biogenesis GO:0070271 263 0.024
intracellular transport GO:0046907 185 0.023
positive regulation of transport GO:0051050 245 0.023
response to peptide GO:1901652 292 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
nucleotide metabolic process GO:0009117 279 0.023
regulation of cellular component organization GO:0051128 368 0.023
regulation of protein localization GO:0032880 81 0.023
regulation of cell projection organization GO:0031344 175 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
reproductive system development GO:0061458 128 0.023
central nervous system development GO:0007417 311 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
development of primary sexual characteristics GO:0045137 107 0.022
macromolecular complex assembly GO:0065003 273 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
ribonucleoside metabolic process GO:0009119 174 0.021
nucleoside metabolic process GO:0009116 179 0.021
cellular lipid metabolic process GO:0044255 208 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
programmed cell death GO:0012501 392 0.021
regulation of hydrolase activity GO:0051336 143 0.021
sex differentiation GO:0007548 113 0.021
neurological system process GO:0050877 219 0.021
regulation of homotypic cell cell adhesion GO:0034110 4 0.021
regulation of interleukin 1 secretion GO:0050704 3 0.021
reproduction GO:0000003 245 0.020
tolerance induction dependent upon immune response GO:0002461 2 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
limbic system development GO:0021761 38 0.020
wound healing GO:0042060 122 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
organic acid metabolic process GO:0006082 292 0.020
positive regulation of cell development GO:0010720 176 0.020
peptide transport GO:0015833 97 0.020
positive regulation of signaling GO:0023056 270 0.019
establishment of protein localization GO:0045184 141 0.019
cellular ketone metabolic process GO:0042180 51 0.019
regulation of dendrite development GO:0050773 59 0.019
epithelial cell differentiation GO:0030855 71 0.019
response to inorganic substance GO:0010035 377 0.019
nucleotide catabolic process GO:0009166 139 0.019
female gonad development GO:0008585 53 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
neuron projection development GO:0031175 273 0.019
cellular response to stress GO:0033554 269 0.019
cell projection morphogenesis GO:0048858 123 0.019
brain development GO:0007420 247 0.018
protein transport GO:0015031 132 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
organic anion transport GO:0015711 132 0.018
peptide secretion GO:0002790 86 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
positive regulation of molecular function GO:0044093 230 0.018
regulation of molecular function GO:0065009 398 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
cellular homeostasis GO:0019725 252 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
protein localization GO:0008104 191 0.018
cell cell signaling GO:0007267 335 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
interleukin 1 beta secretion GO:0050702 3 0.017
cellular component morphogenesis GO:0032989 155 0.017
multicellular organism reproduction GO:0032504 233 0.017
carboxylic acid transport GO:0046942 115 0.017
male gonad development GO:0008584 59 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
response to acid chemical GO:0001101 222 0.017
vasculature development GO:0001944 70 0.017
protein maturation GO:0051604 68 0.017
gamete generation GO:0007276 124 0.017
protein oligomerization GO:0051259 191 0.017
response to metal ion GO:0010038 253 0.017
regulation of neuronal synaptic plasticity GO:0048168 31 0.017
vesicle mediated transport GO:0016192 181 0.017
peptide hormone secretion GO:0030072 84 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
intracellular signal transduction GO:0035556 314 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
rna metabolic process GO:0016070 406 0.016
regulation of catalytic activity GO:0050790 304 0.016
locomotion GO:0040011 237 0.016
regulation of cellular localization GO:0060341 263 0.016
regulation of interleukin 1 beta secretion GO:0050706 3 0.016
regulation of synaptic transmission GO:0050804 141 0.016
regulation of signal transduction GO:0009966 318 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
cell projection organization GO:0030030 302 0.016
interleukin 1 secretion GO:0050701 3 0.016
neuron death GO:0070997 127 0.016
single organism biosynthetic process GO:0044711 342 0.016
response to peptide hormone GO:0043434 278 0.016
lipid transport GO:0006869 61 0.016
vesicle fusion GO:0006906 14 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
apoptotic process GO:0006915 381 0.015
regulation of apoptotic process GO:0042981 335 0.015
amine metabolic process GO:0009308 38 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
luteolysis GO:0001554 5 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
transmission of nerve impulse GO:0019226 42 0.015
regulation of vasculature development GO:1901342 44 0.015
single organism organelle organization GO:1902589 180 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
regulation of cell development GO:0060284 263 0.015
multicellular organismal signaling GO:0035637 44 0.015
organophosphate catabolic process GO:0046434 148 0.015
golgi vesicle transport GO:0048193 22 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
neuron projection morphogenesis GO:0048812 122 0.014
t cell tolerance induction GO:0002517 3 0.014
regulation of hormone levels GO:0010817 187 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of interleukin 1 secretion GO:0050716 3 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
protein processing GO:0016485 68 0.014
sexual reproduction GO:0019953 148 0.014
positive regulation of secretion GO:0051047 140 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.013
single organism cellular localization GO:1902580 102 0.013
posttranscriptional regulation of gene expression GO:0010608 37 0.013
secretion GO:0046903 307 0.013
regulation of programmed cell death GO:0043067 341 0.013
regulation of membrane potential GO:0042391 110 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
membrane organization GO:0061024 94 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
retinal cell programmed cell death GO:0046666 1 0.013
ras protein signal transduction GO:0007265 29 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
regulation of response to external stimulus GO:0032101 106 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
cell part morphogenesis GO:0032990 123 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
protein localization to membrane GO:0072657 36 0.013
transcription dna templated GO:0006351 377 0.013
regulation of organelle organization GO:0033043 80 0.013
inflammatory response GO:0006954 150 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
male sex differentiation GO:0046661 64 0.012
nucleoside catabolic process GO:0009164 126 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
epithelium development GO:0060429 96 0.012
cell cycle GO:0007049 101 0.012
regulation of peptidase activity GO:0052547 55 0.012
male gamete generation GO:0048232 99 0.012
anion transport GO:0006820 178 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
gtp metabolic process GO:0046039 72 0.012
macromolecule catabolic process GO:0009057 58 0.012
single organism membrane organization GO:0044802 74 0.012
axon development GO:0061564 96 0.012
glomerular mesangium development GO:0072109 4 0.012
regulation of neuron projection development GO:0010975 161 0.012
exocytosis GO:0006887 60 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
phenylpropanoid catabolic process GO:0046271 3 0.012
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
neuromuscular process GO:0050905 2 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
cell migration GO:0016477 197 0.012
cardiovascular system development GO:0072358 134 0.011
neuron fate commitment GO:0048663 4 0.011
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.011
cellular response to lipid GO:0071396 201 0.011
purine containing compound catabolic process GO:0072523 138 0.011
response to insulin GO:0032868 133 0.011
regulation of neurogenesis GO:0050767 247 0.011
response to radiation GO:0009314 137 0.011
cellular amine metabolic process GO:0044106 38 0.011
cell cycle process GO:0022402 57 0.011
amino acid transport GO:0006865 70 0.011
regulation of cell differentiation GO:0045595 320 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
positive regulation of catabolic process GO:0009896 78 0.011
negative regulation of molecular function GO:0044092 133 0.011
protein complex assembly GO:0006461 263 0.011
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.011
regulation of tolerance induction to nonself antigen GO:0002655 1 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
forebrain development GO:0030900 98 0.011
axonogenesis GO:0007409 71 0.011
fertilization GO:0009566 3 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
adult locomotory behavior GO:0008344 4 0.011
cell junction assembly GO:0034329 18 0.011
single organism membrane fusion GO:0044801 17 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
response to toxic substance GO:0009636 133 0.011
organelle organization GO:0006996 266 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
negative regulation of secretion GO:0051048 82 0.010
cell morphogenesis GO:0000902 142 0.010
cell type specific apoptotic process GO:0097285 134 0.010
regulation of nervous system development GO:0051960 264 0.010
response to decreased oxygen levels GO:0036293 237 0.010
gtp catabolic process GO:0006184 71 0.010
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
regulation of actin cytoskeleton organization GO:0032956 30 0.010
synaptic transmission GO:0007268 235 0.010
positive regulation of cell communication GO:0010647 271 0.010
response to oxygen levels GO:0070482 265 0.010
organelle inheritance GO:0048308 2 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
protein complex subunit organization GO:0071822 302 0.010
homeostatic process GO:0042592 331 0.010
response to oxidative stress GO:0006979 186 0.010
transmembrane transport GO:0055085 412 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
spermatogenesis GO:0007283 99 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
reproductive structure development GO:0048608 128 0.010
single fertilization GO:0007338 3 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
response to hexose GO:0009746 144 0.010
mitotic dna damage checkpoint GO:0044773 1 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010

Leprot disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
central nervous system disease DOID:331 0 0.010
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010