Rattus norvegicus

21 known processes

Slc21a4

kidney specific organic anion transporter

(Aliases: OAT-K2,rOAT-K1,rOAT-K3,OAT-K1,rOAT-K5,rOAT-K7,rOAT-K6,rOAT-K9,rOAT-K14,rOAT-K11,rOAT-K13,rOAT-K2,Slco1a3,rOAT-K8)

Slc21a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.173
cation transmembrane transport GO:0098655 263 0.127
ion transmembrane transport GO:0034220 365 0.069
Rat
response to metal ion GO:0010038 253 0.065
regulation of programmed cell death GO:0043067 341 0.058
response to nutrient levels GO:0031667 370 0.058
forebrain development GO:0030900 98 0.052
regulation of phosphorylation GO:0042325 248 0.052
blood circulation GO:0008015 183 0.047
response to extracellular stimulus GO:0009991 380 0.047
response to glucocorticoid GO:0051384 223 0.046
Rat
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.044
organonitrogen compound catabolic process GO:1901565 179 0.044
response to transition metal nanoparticle GO:1990267 122 0.043
glycosyl compound metabolic process GO:1901657 182 0.042
tube development GO:0035295 89 0.042
small molecule biosynthetic process GO:0044283 124 0.041
aromatic compound catabolic process GO:0019439 168 0.041
nucleoside triphosphate metabolic process GO:0009141 144 0.040
choline transport GO:0015871 4 0.040
nucleoside metabolic process GO:0009116 179 0.040
cellular catabolic process GO:0044248 295 0.039
response to corticosteroid GO:0031960 235 0.039
Rat
anion transport GO:0006820 178 0.037
regulation of cell proliferation GO:0042127 359 0.037
vesicle mediated transport GO:0016192 181 0.035
organic substance catabolic process GO:1901575 316 0.035
single organism catabolic process GO:0044712 283 0.034
regulation of catalytic activity GO:0050790 304 0.033
inorganic cation transmembrane transport GO:0098662 202 0.032
response to cytokine GO:0034097 215 0.031
Rat
ossification GO:0001503 70 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
cation transport GO:0006812 382 0.030
regulation of tube size GO:0035150 89 0.029
circulatory system process GO:0003013 183 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.028
regulation of neurogenesis GO:0050767 247 0.028
circadian rhythm GO:0007623 88 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.028
chemical homeostasis GO:0048878 292 0.028
single organism biosynthetic process GO:0044711 342 0.028
cellular response to lipid GO:0071396 201 0.027
intracellular signal transduction GO:0035556 314 0.027
nitrogen compound transport GO:0071705 229 0.027
protein homooligomerization GO:0051260 91 0.027
sodium ion transport GO:0006814 82 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
purine nucleoside metabolic process GO:0042278 169 0.024
heterocycle catabolic process GO:0046700 167 0.024
nucleoside catabolic process GO:0009164 126 0.023
protein complex subunit organization GO:0071822 302 0.023
positive regulation of nervous system development GO:0051962 178 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.022
response to inorganic substance GO:0010035 377 0.022
homeostatic process GO:0042592 331 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
negative regulation of neuron death GO:1901215 69 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
positive regulation of cell death GO:0010942 184 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
catabolic process GO:0009056 351 0.020
metal ion transport GO:0030001 289 0.020
vasoconstriction GO:0042310 54 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
renal system development GO:0072001 67 0.020
organic anion transport GO:0015711 132 0.020
regulation of cell projection organization GO:0031344 175 0.019
cellular component biogenesis GO:0044085 368 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
parturition GO:0007567 10 0.019
organic acid transport GO:0015849 116 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
positive regulation of developmental process GO:0051094 283 0.018
actin filament based process GO:0030029 86 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
positive regulation of cell communication GO:0010647 271 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
regulation of neuron differentiation GO:0045664 208 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
response to peptide GO:1901652 292 0.018
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
regulation of metal ion transport GO:0010959 118 0.017
hormone biosynthetic process GO:0042446 25 0.017
regulation of nervous system development GO:0051960 264 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
macromolecular complex assembly GO:0065003 273 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
positive regulation of ion transport GO:0043270 94 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
aging GO:0007568 241 0.016
rhythmic process GO:0048511 156 0.016
lipid biosynthetic process GO:0008610 128 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
reproduction GO:0000003 245 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
regulation of anatomical structure size GO:0090066 135 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.015
response to estradiol GO:0032355 164 0.015
respiratory system development GO:0060541 45 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
appendage morphogenesis GO:0035107 4 0.015
protein complex assembly GO:0006461 263 0.015
cellular chemical homeostasis GO:0055082 247 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of growth GO:0040008 105 0.015
hormone metabolic process GO:0042445 69 0.015
Rat
regulation of cell differentiation GO:0045595 320 0.015
regulation of blood pressure GO:0008217 83 0.014
single organism cell adhesion GO:0098602 46 0.014
transmembrane transport GO:0055085 412 0.014
Rat
regulation of cellular component organization GO:0051128 368 0.014
multicellular organismal signaling GO:0035637 44 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
proteolysis GO:0006508 175 0.014
negative regulation of innate immune response GO:0045824 4 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of signal transduction GO:0009966 318 0.014
amino acid transport GO:0006865 70 0.013
Rat
negative regulation of cell death GO:0060548 229 0.013
l glutamate import GO:0051938 2 0.013
organophosphate catabolic process GO:0046434 148 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
programmed cell death GO:0012501 392 0.013
cellular component movement GO:0006928 248 0.013
response to blue light GO:0009637 1 0.013
activation of janus kinase activity GO:0042976 5 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
regulation of cellular component movement GO:0051270 150 0.013
response to peptide hormone GO:0043434 278 0.012
Rat
immune system process GO:0002376 204 0.012
insecticide metabolic process GO:0017143 4 0.012
cellular component assembly GO:0022607 360 0.012
purine containing compound metabolic process GO:0072521 253 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
regulation of secretion by cell GO:1903530 208 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
response to estrogen GO:0043627 232 0.012
multicellular organism growth GO:0035264 1 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
regulation of neuron projection development GO:0010975 161 0.012
purine containing compound catabolic process GO:0072523 138 0.012
biological adhesion GO:0022610 110 0.012
monocarboxylic acid transport GO:0015718 52 0.012
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
cell adhesion GO:0007155 110 0.012
protein oligomerization GO:0051259 191 0.012
cellular response to hormone stimulus GO:0032870 247 0.011
neuron projection development GO:0031175 273 0.011
hepaticobiliary system development GO:0061008 90 0.011
Rat
regulation of cellular localization GO:0060341 263 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
regulation of muscle system process GO:0090257 79 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
growth GO:0040007 165 0.011
neuron development GO:0048666 286 0.011
ras protein signal transduction GO:0007265 29 0.011
carboxylic acid transport GO:0046942 115 0.011
urogenital system development GO:0001655 78 0.011
peptide transport GO:0015833 97 0.011
Rat
epithelial cell proliferation GO:0050673 54 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
regulation of cell growth GO:0001558 85 0.011
protein complex biogenesis GO:0070271 263 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
secretion GO:0046903 307 0.011
muscle system process GO:0003012 115 0.011
regulation of immune system process GO:0002682 123 0.011
defense response to gram positive bacterium GO:0050830 2 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
cell type specific apoptotic process GO:0097285 134 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
neuron differentiation GO:0030182 368 0.010
negative regulation of metabolic process GO:0009892 331 0.010
regulation of phosphate metabolic process GO:0019220 349 0.010
regulation of system process GO:0044057 208 0.010
cytoskeleton organization GO:0007010 111 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
multi multicellular organism process GO:0044706 138 0.010
negative regulation of cell development GO:0010721 82 0.010
respiratory tube development GO:0030323 43 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
response to bacterium GO:0009617 200 0.010
Rat
intracellular transport GO:0046907 185 0.010
neuron death GO:0070997 127 0.010
cellular homeostasis GO:0019725 252 0.010
response to vitamin GO:0033273 131 0.010
cellular response to monosaccharide stimulus GO:0071326 67 0.010
modified amino acid transport GO:0072337 12 0.010
Rat

Slc21a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
central nervous system disease DOID:331 0 0.014
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
brain disease DOID:936 0 0.012