Rattus norvegicus

0 known processes

Crim1

cysteine rich transmembrane BMP regulator 1 (chordin like)

Crim1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.115
anatomical structure morphogenesis GO:0009653 298 0.101
nucleic acid templated transcription GO:0097659 379 0.087
protein phosphorylation GO:0006468 345 0.086
regulation of nucleic acid templated transcription GO:1903506 380 0.086
programmed cell death GO:0012501 392 0.085
rna metabolic process GO:0016070 406 0.084
single organism reproductive process GO:0044702 297 0.080
regulation of transcription dna templated GO:0006355 374 0.076
regulation of apoptotic process GO:0042981 335 0.074
apoptotic process GO:0006915 381 0.072
positive regulation of molecular function GO:0044093 230 0.071
transcription dna templated GO:0006351 377 0.070
neuron differentiation GO:0030182 368 0.068
Rat
intracellular signal transduction GO:0035556 314 0.067
tissue development GO:0009888 252 0.065
regulation of protein modification process GO:0031399 194 0.065
regulation of cell proliferation GO:0042127 359 0.062
regulation of signal transduction GO:0009966 318 0.062
cell projection organization GO:0030030 302 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
regulation of cellular component movement GO:0051270 150 0.061
negative regulation of metabolic process GO:0009892 331 0.060
rna biosynthetic process GO:0032774 380 0.060
regulation of phosphorus metabolic process GO:0051174 349 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
positive regulation of locomotion GO:0040017 102 0.057
positive regulation of gene expression GO:0010628 244 0.056
regulation of protein metabolic process GO:0051246 289 0.056
cellular component movement GO:0006928 248 0.055
positive regulation of rna biosynthetic process GO:1902680 197 0.054
regulation of molecular function GO:0065009 398 0.053
regulation of cell differentiation GO:0045595 320 0.053
locomotion GO:0040011 237 0.052
reproduction GO:0000003 245 0.052
positive regulation of biosynthetic process GO:0009891 319 0.051
regulation of phosphate metabolic process GO:0019220 349 0.051
positive regulation of cellular biosynthetic process GO:0031328 295 0.050
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
regulation of phosphorylation GO:0042325 248 0.049
regulation of protein phosphorylation GO:0001932 183 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
positive regulation of cell death GO:0010942 184 0.047
neuron development GO:0048666 286 0.046
response to estrogen GO:0043627 232 0.046
oxoacid metabolic process GO:0043436 290 0.046
regulation of rna biosynthetic process GO:2001141 381 0.045
cellular response to oxygen containing compound GO:1901701 386 0.045
regulation of cell motility GO:2000145 131 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.043
regulation of intracellular signal transduction GO:1902531 218 0.042
response to inorganic substance GO:0010035 377 0.042
cell motility GO:0048870 202 0.041
regulation of catalytic activity GO:0050790 304 0.041
cellular ketone metabolic process GO:0042180 51 0.041
circulatory system development GO:0072359 134 0.040
multicellular organism reproduction GO:0032504 233 0.039
cell morphogenesis GO:0000902 142 0.039
reproductive process GO:0022414 372 0.039
negative regulation of cell proliferation GO:0008285 119 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
cardiovascular system development GO:0072358 134 0.037
positive regulation of cell proliferation GO:0008284 249 0.036
rhythmic process GO:0048511 156 0.036
positive regulation of programmed cell death GO:0043068 157 0.036
cell type specific apoptotic process GO:0097285 134 0.036
carboxylic acid metabolic process GO:0019752 289 0.035
positive regulation of phosphorus metabolic process GO:0010562 262 0.035
amine metabolic process GO:0009308 38 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
negative regulation of apoptotic process GO:0043066 181 0.034
positive regulation of cell differentiation GO:0045597 217 0.034
neuron projection development GO:0031175 273 0.034
negative regulation of gene expression GO:0010629 199 0.034
positive regulation of response to stimulus GO:0048584 285 0.034
gland development GO:0048732 155 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.033
cell migration GO:0016477 197 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.033
response to wounding GO:0009611 254 0.033
regulation of rna metabolic process GO:0051252 391 0.033
positive regulation of rna metabolic process GO:0051254 203 0.033
cellular response to stress GO:0033554 269 0.032
cell cell signaling GO:0007267 335 0.032
cellular response to organic cyclic compound GO:0071407 202 0.032
central nervous system development GO:0007417 311 0.032
regulation of mapk cascade GO:0043408 116 0.032
response to acid chemical GO:0001101 222 0.032
cell part morphogenesis GO:0032990 123 0.031
response to peptide GO:1901652 292 0.031
regulation of cell development GO:0060284 263 0.031
cell morphogenesis involved in differentiation GO:0000904 119 0.031
cell cycle GO:0007049 101 0.031
positive regulation of signaling GO:0023056 270 0.031
negative regulation of biosynthetic process GO:0009890 168 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
cell projection morphogenesis GO:0048858 123 0.030
taxis GO:0042330 67 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
positive regulation of developmental process GO:0051094 283 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
positive regulation of cell migration GO:0030335 96 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
cellular component biogenesis GO:0044085 368 0.029
multi organism reproductive process GO:0044703 262 0.029
negative regulation of cell communication GO:0010648 158 0.029
positive regulation of cell development GO:0010720 176 0.029
secretion GO:0046903 307 0.029
cellular response to lipid GO:0071396 201 0.029
cellular component morphogenesis GO:0032989 155 0.028
organic acid metabolic process GO:0006082 292 0.028
developmental process involved in reproduction GO:0003006 159 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
regulation of system process GO:0044057 208 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
cellular amine metabolic process GO:0044106 38 0.028
head development GO:0060322 247 0.028
signal transduction by phosphorylation GO:0023014 144 0.027
negative regulation of signaling GO:0023057 157 0.027
negative regulation of cell death GO:0060548 229 0.027
response to growth factor GO:0070848 189 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
response to nutrient levels GO:0031667 370 0.027
regulation of locomotion GO:0040012 148 0.027
neuron apoptotic process GO:0051402 88 0.027
brain development GO:0007420 247 0.027
ras protein signal transduction GO:0007265 29 0.027
positive regulation of cellular component movement GO:0051272 102 0.026
heart development GO:0007507 72 0.026
positive regulation of apoptotic process GO:0043065 154 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
chemical homeostasis GO:0048878 292 0.025
lipid metabolic process GO:0006629 283 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
response to monosaccharide GO:0034284 159 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
axon development GO:0061564 96 0.025
response to extracellular stimulus GO:0009991 380 0.025
positive regulation of cell communication GO:0010647 271 0.025
positive regulation of protein metabolic process GO:0051247 178 0.024
metal ion transport GO:0030001 289 0.024
negative regulation of developmental process GO:0051093 125 0.024
cellular component assembly GO:0022607 360 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
homeostatic process GO:0042592 331 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
regulation of establishment of planar polarity GO:0090175 2 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
response to bacterium GO:0009617 200 0.023
reproductive system development GO:0061458 128 0.023
regulation of secretion by cell GO:1903530 208 0.023
neuron projection morphogenesis GO:0048812 122 0.023
response to carbohydrate GO:0009743 183 0.023
regulation of nervous system development GO:0051960 264 0.023
reproductive structure development GO:0048608 128 0.023
macromolecule localization GO:0033036 252 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cellular homeostasis GO:0019725 252 0.022
heart morphogenesis GO:0003007 3 0.022
mapk cascade GO:0000165 140 0.022
positive regulation of protein modification process GO:0031401 142 0.022
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
biological adhesion GO:0022610 110 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.021
positive regulation of signal transduction GO:0009967 175 0.021
regeneration GO:0031099 163 0.021
establishment of tissue polarity GO:0007164 2 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
regulation of membrane potential GO:0042391 110 0.021
positive regulation of nervous system development GO:0051962 178 0.021
catabolic process GO:0009056 351 0.021
localization of cell GO:0051674 202 0.021
regulation of protein kinase activity GO:0045859 105 0.020
regulation of cell migration GO:0030334 128 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
response to external biotic stimulus GO:0043207 221 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
response to other organism GO:0051707 220 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
response to hexose GO:0009746 144 0.020
regulation of hormone levels GO:0010817 187 0.020
transmembrane transport GO:0055085 412 0.020
organ morphogenesis GO:0009887 75 0.019
aging GO:0007568 241 0.019
response to peptide hormone GO:0043434 278 0.019
response to lipopolysaccharide GO:0032496 191 0.019
metal ion homeostasis GO:0055065 186 0.019
development of primary sexual characteristics GO:0045137 107 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
single organism biosynthetic process GO:0044711 342 0.019
macromolecular complex assembly GO:0065003 273 0.019
mesenchymal cell proliferation GO:0010463 4 0.019
regulation of neurogenesis GO:0050767 247 0.019
calcium ion homeostasis GO:0055074 162 0.019
protein complex biogenesis GO:0070271 263 0.019
cellular ion homeostasis GO:0006873 184 0.018
regulation of transferase activity GO:0051338 123 0.018
muscle system process GO:0003012 115 0.018
circulatory system process GO:0003013 183 0.018
response to metal ion GO:0010038 253 0.018
ion transmembrane transport GO:0034220 365 0.018
cellular lipid metabolic process GO:0044255 208 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
protein complex assembly GO:0006461 263 0.018
response to cytokine GO:0034097 215 0.018
response to glucose GO:0009749 136 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
regulation of cellular localization GO:0060341 263 0.018
anion transport GO:0006820 178 0.018
regulation of neuron differentiation GO:0045664 208 0.018
negative regulation of molecular function GO:0044092 133 0.018
response to ketone GO:1901654 182 0.018
ion homeostasis GO:0050801 212 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
response to decreased oxygen levels GO:0036293 237 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
protein complex subunit organization GO:0071822 302 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of cell projection organization GO:0031344 175 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
secretion by cell GO:0032940 248 0.017
organic substance catabolic process GO:1901575 316 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
calcium ion transport GO:0006816 131 0.016
regulation of secretion GO:0051046 224 0.016
sexual reproduction GO:0019953 148 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
cation transport GO:0006812 382 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
response to reactive oxygen species GO:0000302 120 0.016
eye morphogenesis GO:0048592 4 0.016
single organism catabolic process GO:0044712 283 0.016
divalent metal ion transport GO:0070838 132 0.016
regulation of ion transport GO:0043269 245 0.016
regulation of cell cycle GO:0051726 73 0.016
axonogenesis GO:0007409 71 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
response to interleukin 1 GO:0070555 55 0.016
gamete generation GO:0007276 124 0.016
anterior posterior pattern specification GO:0009952 1 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
immune system process GO:0002376 204 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
protein oligomerization GO:0051259 191 0.015
growth GO:0040007 165 0.015
response to estradiol GO:0032355 164 0.015
regulation of cellular component organization GO:0051128 368 0.015
sex differentiation GO:0007548 113 0.015
organophosphate metabolic process GO:0019637 370 0.015
negative regulation of signal transduction GO:0009968 83 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
response to radiation GO:0009314 137 0.015
regulation of response to stress GO:0080134 126 0.015
morphogenesis of a polarized epithelium GO:0001738 1 0.015
response to glucocorticoid GO:0051384 223 0.015
regulation of neuron death GO:1901214 115 0.015
positive regulation of secretion GO:0051047 140 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
cellular response to oxidative stress GO:0034599 76 0.014
regulation of kinase activity GO:0043549 117 0.014
negative regulation of transport GO:0051051 136 0.014
response to vitamin GO:0033273 131 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.014
axis specification GO:0009798 4 0.014
response to oxidative stress GO:0006979 186 0.014
response to mechanical stimulus GO:0009612 134 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
cell adhesion GO:0007155 110 0.014
muscle contraction GO:0006936 88 0.014
regulation of catabolic process GO:0009894 113 0.014
bmp signaling pathway GO:0030509 4 0.014
muscle structure development GO:0061061 87 0.014
establishment of planar polarity GO:0001736 1 0.014
regulation of response to external stimulus GO:0032101 106 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
nucleotide metabolic process GO:0009117 279 0.014
gonad development GO:0008406 104 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
salivary gland development GO:0007431 3 0.014
positive regulation of cell projection organization GO:0031346 111 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
proteolysis GO:0006508 175 0.013
positive regulation of catabolic process GO:0009896 78 0.013
neuron death GO:0070997 127 0.013
wound healing GO:0042060 122 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
cellular cation homeostasis GO:0030003 180 0.013
ovulation cycle GO:0042698 67 0.013
regulation of synaptic transmission GO:0050804 141 0.013
epithelium development GO:0060429 96 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
regulation of neuron projection development GO:0010975 161 0.013
chemotaxis GO:0006935 66 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of growth GO:0040008 105 0.013
blood circulation GO:0008015 183 0.012
response to oxygen levels GO:0070482 265 0.012
regulation of cell adhesion GO:0030155 52 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
motor neuron axon guidance GO:0008045 1 0.012
cell activation GO:0001775 97 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
response to toxic substance GO:0009636 133 0.012
female pregnancy GO:0007565 122 0.012
lipid storage GO:0019915 1 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
negative regulation of secretion GO:0051048 82 0.012
defense response GO:0006952 194 0.012
oxidation reduction process GO:0055114 304 0.012
response to corticosteroid GO:0031960 235 0.012
cellular response to alcohol GO:0097306 87 0.012
protein transport GO:0015031 132 0.012
behavior GO:0007610 205 0.012
response to hypoxia GO:0001666 231 0.012
embryonic pattern specification GO:0009880 1 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
organelle organization GO:0006996 266 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of transmembrane transport GO:0034762 122 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
response to hydrogen peroxide GO:0042542 89 0.012
tube development GO:0035295 89 0.012
regulation of muscle system process GO:0090257 79 0.012
response to nutrient GO:0007584 248 0.012
regulation of cellular component biogenesis GO:0044087 86 0.011
organic acid transport GO:0015849 116 0.011
dendrite development GO:0016358 72 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
regulation of protein localization GO:0032880 81 0.011
nucleotide catabolic process GO:0009166 139 0.011
action potential GO:0001508 54 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
hormone secretion GO:0046879 115 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
synaptic transmission GO:0007268 235 0.011
purine containing compound metabolic process GO:0072521 253 0.011
transmission of nerve impulse GO:0019226 42 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
spermatogenesis GO:0007283 99 0.011
ovulation cycle process GO:0022602 50 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
cell cycle checkpoint GO:0000075 2 0.011
response to ethanol GO:0045471 162 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
female gonad development GO:0008585 53 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
multi multicellular organism process GO:0044706 138 0.011
regulation of metal ion transport GO:0010959 118 0.011
female sex differentiation GO:0046660 59 0.011
forebrain development GO:0030900 98 0.011
neuromuscular process GO:0050905 2 0.011
immune response GO:0006955 104 0.011
urinary tract smooth muscle contraction GO:0014848 4 0.011
nitrogen compound transport GO:0071705 229 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
multicellular organism growth GO:0035264 1 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
muscle tissue development GO:0060537 58 0.011
glucose homeostasis GO:0042593 75 0.010
response to tumor necrosis factor GO:0034612 56 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
muscle cell proliferation GO:0033002 84 0.010
response to calcium ion GO:0051592 59 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
positive regulation of transport GO:0051050 245 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
respiratory system development GO:0060541 45 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
establishment of protein localization GO:0045184 141 0.010
regulation of homeostatic process GO:0032844 101 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
hepaticobiliary system development GO:0061008 90 0.010
positive regulation of kinase activity GO:0033674 77 0.010
regulation of saliva secretion GO:0046877 3 0.010

Crim1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.011
sensory system disease DOID:0050155 0 0.011