Rattus norvegicus

0 known processes

Cdc42ep3

CDC42 effector protein (Rho GTPase binding) 3

Cdc42ep3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 281 0.104
nucleic acid templated transcription GO:0097659 379 0.103
cellular amino acid metabolic process GO:0006520 107 0.101
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.094
regulation of signal transduction GO:0009966 318 0.094
regulation of transcription dna templated GO:0006355 374 0.091
response to growth factor GO:0070848 189 0.086
positive regulation of cell differentiation GO:0045597 217 0.085
negative regulation of macromolecule metabolic process GO:0010605 260 0.084
regulation of nucleic acid templated transcription GO:1903506 380 0.083
rna metabolic process GO:0016070 406 0.081
regulation of rna metabolic process GO:0051252 391 0.075
positive regulation of cell communication GO:0010647 271 0.074
organic acid metabolic process GO:0006082 292 0.071
carboxylic acid metabolic process GO:0019752 289 0.066
response to inorganic substance GO:0010035 377 0.066
regulation of rna biosynthetic process GO:2001141 381 0.063
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.063
cellular response to organic cyclic compound GO:0071407 202 0.062
negative regulation of cellular biosynthetic process GO:0031327 161 0.060
positive regulation of biosynthetic process GO:0009891 319 0.060
rna biosynthetic process GO:0032774 380 0.059
regulation of molecular function GO:0065009 398 0.059
transcription dna templated GO:0006351 377 0.059
oxoacid metabolic process GO:0043436 290 0.059
regulation of programmed cell death GO:0043067 341 0.056
cellular response to endogenous stimulus GO:0071495 377 0.055
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
apoptotic process GO:0006915 381 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.053
programmed cell death GO:0012501 392 0.052
central nervous system development GO:0007417 311 0.052
regulation of cellular amino acid metabolic process GO:0006521 2 0.051
regulation of cellular protein metabolic process GO:0032268 267 0.050
cellular response to growth factor stimulus GO:0071363 162 0.050
response to cytokine GO:0034097 215 0.048
regulation of protein metabolic process GO:0051246 289 0.046
negative regulation of gene expression GO:0010629 199 0.046
cellular response to oxygen containing compound GO:1901701 386 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.046
transcription from rna polymerase ii promoter GO:0006366 252 0.045
response to nutrient levels GO:0031667 370 0.044
amine metabolic process GO:0009308 38 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
regulation of cell differentiation GO:0045595 320 0.043
intracellular signal transduction GO:0035556 314 0.042
protein phosphorylation GO:0006468 345 0.042
negative regulation of cell death GO:0060548 229 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
positive regulation of multicellular organismal process GO:0051240 387 0.042
positive regulation of developmental process GO:0051094 283 0.042
regulation of intracellular signal transduction GO:1902531 218 0.042
regulation of multicellular organismal development GO:2000026 376 0.041
negative regulation of apoptotic process GO:0043066 181 0.041
regulation of cell proliferation GO:0042127 359 0.040
cellular amine metabolic process GO:0044106 38 0.040
regulation of neurogenesis GO:0050767 247 0.040
cellular response to nitrogen compound GO:1901699 210 0.040
neuron differentiation GO:0030182 368 0.039
regulation of cellular component organization GO:0051128 368 0.039
positive regulation of cell proliferation GO:0008284 249 0.038
positive regulation of response to stimulus GO:0048584 285 0.038
cellular ketone metabolic process GO:0042180 51 0.038
cellular response to lipid GO:0071396 201 0.038
carbohydrate metabolic process GO:0005975 130 0.037
positive regulation of rna metabolic process GO:0051254 203 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.036
cellular component biogenesis GO:0044085 368 0.036
response to extracellular stimulus GO:0009991 380 0.036
cation transport GO:0006812 382 0.036
carbohydrate derivative biosynthetic process GO:1901137 124 0.036
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
regulation of cellular localization GO:0060341 263 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
negative regulation of rna metabolic process GO:0051253 123 0.034
cellular component assembly GO:0022607 360 0.034
negative regulation of signaling GO:0023057 157 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
positive regulation of cell death GO:0010942 184 0.034
regulation of apoptotic process GO:0042981 335 0.034
protein complex subunit organization GO:0071822 302 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
regulation of canonical wnt signaling pathway GO:0060828 4 0.033
positive regulation of signal transduction GO:0009967 175 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
muscle system process GO:0003012 115 0.033
regulation of protein phosphorylation GO:0001932 183 0.032
regulation of neuron differentiation GO:0045664 208 0.032
cell migration GO:0016477 197 0.031
neuron projection development GO:0031175 273 0.031
regulation of cell development GO:0060284 263 0.031
response to oxygen levels GO:0070482 265 0.031
cellular response to stress GO:0033554 269 0.031
cell cell signaling GO:0007267 335 0.031
positive regulation of cellular amine metabolic process GO:0033240 3 0.031
response to acid chemical GO:0001101 222 0.030
cellular component movement GO:0006928 248 0.030
response to other organism GO:0051707 220 0.030
response to retinoic acid GO:0032526 63 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
negative regulation of rna biosynthetic process GO:1902679 118 0.030
positive regulation of nervous system development GO:0051962 178 0.029
positive regulation of transcription dna templated GO:0045893 197 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
response to metal ion GO:0010038 253 0.029
positive regulation of cellular component organization GO:0051130 200 0.028
regulation of protein modification process GO:0031399 194 0.028
regulation of mapk cascade GO:0043408 116 0.028
single organism organelle organization GO:1902589 180 0.028
positive regulation of gene expression GO:0010628 244 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
positive regulation of signaling GO:0023056 270 0.027
muscle structure development GO:0061061 87 0.027
protein complex biogenesis GO:0070271 263 0.027
cellular lipid metabolic process GO:0044255 208 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
cardiovascular system development GO:0072358 134 0.027
neurological system process GO:0050877 219 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
regulation of phosphorylation GO:0042325 248 0.026
cellular response to cytokine stimulus GO:0071345 127 0.026
neuron development GO:0048666 286 0.026
regulation of stem cell differentiation GO:2000736 2 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
response to temperature stimulus GO:0009266 94 0.025
negative regulation of programmed cell death GO:0043069 183 0.024
cell projection organization GO:0030030 302 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
organophosphate metabolic process GO:0019637 370 0.024
metal ion transport GO:0030001 289 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
secretion GO:0046903 307 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
protein complex assembly GO:0006461 263 0.023
positive regulation of cell development GO:0010720 176 0.022
response to oxidative stress GO:0006979 186 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
negative regulation of cell communication GO:0010648 158 0.022
regulation of catalytic activity GO:0050790 304 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
response to decreased oxygen levels GO:0036293 237 0.021
cellular catabolic process GO:0044248 295 0.021
response to wounding GO:0009611 254 0.021
proteolysis GO:0006508 175 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
negative regulation of developmental process GO:0051093 125 0.021
inorganic cation transmembrane transport GO:0098662 202 0.021
cell motility GO:0048870 202 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
negative regulation of metabolic process GO:0009892 331 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
positive regulation of cellular component movement GO:0051272 102 0.021
positive regulation of molecular function GO:0044093 230 0.020
regulation of synaptic transmission GO:0050804 141 0.020
response to peptide hormone GO:0043434 278 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
lipid metabolic process GO:0006629 283 0.020
regulation of system process GO:0044057 208 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
cellular chemical homeostasis GO:0055082 247 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
response to hypoxia GO:0001666 231 0.020
behavior GO:0007610 205 0.020
regulation of cell projection organization GO:0031344 175 0.019
regulation of neuron projection development GO:0010975 161 0.019
macromolecule localization GO:0033036 252 0.019
mapk cascade GO:0000165 140 0.019
regulation of nervous system development GO:0051960 264 0.019
catabolic process GO:0009056 351 0.019
nitrogen compound transport GO:0071705 229 0.019
ion homeostasis GO:0050801 212 0.019
single organism biosynthetic process GO:0044711 342 0.019
response to bacterium GO:0009617 200 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
blood circulation GO:0008015 183 0.019
divalent metal ion transport GO:0070838 132 0.019
response to ethanol GO:0045471 162 0.019
organelle organization GO:0006996 266 0.019
synaptic transmission GO:0007268 235 0.019
ion transmembrane transport GO:0034220 365 0.019
erk1 and erk2 cascade GO:0070371 48 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
peptidyl amino acid modification GO:0018193 126 0.018
response to toxic substance GO:0009636 133 0.018
cell morphogenesis GO:0000902 142 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
transmembrane transport GO:0055085 412 0.018
cellular response to acid chemical GO:0071229 75 0.018
action potential GO:0001508 54 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
intracellular transport GO:0046907 185 0.018
behavioral response to ethanol GO:0048149 1 0.018
single organism intracellular transport GO:1902582 166 0.018
organic substance catabolic process GO:1901575 316 0.018
brain development GO:0007420 247 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
gastrulation GO:0007369 2 0.017
response to amine GO:0014075 46 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
regulation of cytokine production GO:0001817 56 0.017
head development GO:0060322 247 0.017
positive regulation of cytokine production GO:0001819 42 0.017
regulation of ion transport GO:0043269 245 0.017
cellular homeostasis GO:0019725 252 0.017
cation transmembrane transport GO:0098655 263 0.017
homeostatic process GO:0042592 331 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
nucleotide metabolic process GO:0009117 279 0.017
circulatory system development GO:0072359 134 0.017
response to estradiol GO:0032355 164 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
metal ion homeostasis GO:0055065 186 0.017
cellular protein localization GO:0034613 122 0.016
positive regulation of protein modification process GO:0031401 142 0.016
circulatory system process GO:0003013 183 0.016
cellular macromolecule localization GO:0070727 122 0.016
regulation of cellular component movement GO:0051270 150 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
glycosaminoglycan biosynthetic process GO:0006024 4 0.016
single organism reproductive process GO:0044702 297 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
gliogenesis GO:0042063 93 0.016
macromolecular complex assembly GO:0065003 273 0.016
response to lipopolysaccharide GO:0032496 191 0.016
response to alkaloid GO:0043279 132 0.016
regulation of cell migration GO:0030334 128 0.016
cellular ion homeostasis GO:0006873 184 0.016
response to hexose GO:0009746 144 0.016
response to external biotic stimulus GO:0043207 221 0.016
response to glucocorticoid GO:0051384 223 0.015
secretion by cell GO:0032940 248 0.015
response to purine containing compound GO:0014074 126 0.015
localization of cell GO:0051674 202 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
anion transport GO:0006820 178 0.015
cell cycle checkpoint GO:0000075 2 0.015
glial cell differentiation GO:0010001 65 0.015
embryonic pattern specification GO:0009880 1 0.015
regulation of membrane potential GO:0042391 110 0.015
cellular component morphogenesis GO:0032989 155 0.015
response to nutrient GO:0007584 248 0.015
regulation of erk1 and erk2 cascade GO:0070372 41 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
gland development GO:0048732 155 0.015
response to estrogen GO:0043627 232 0.015
cellular response to oxidative stress GO:0034599 76 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
response to glucose GO:0009749 136 0.014
multicellular organismal signaling GO:0035637 44 0.014
ras protein signal transduction GO:0007265 29 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
calcium ion homeostasis GO:0055074 162 0.014
response to monosaccharide GO:0034284 159 0.014
tube development GO:0035295 89 0.014
regulation of kinase activity GO:0043549 117 0.014
cation homeostasis GO:0055080 195 0.014
neuron death GO:0070997 127 0.014
single organism behavior GO:0044708 130 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
regulation of locomotion GO:0040012 148 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to reactive oxygen species GO:0000302 120 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.014
protein localization GO:0008104 191 0.014
single organism catabolic process GO:0044712 283 0.014
response to amino acid GO:0043200 75 0.014
response to carbohydrate GO:0009743 183 0.014
aging GO:0007568 241 0.014
multicellular organism reproduction GO:0032504 233 0.014
response to peptide GO:1901652 292 0.014
growth GO:0040007 165 0.014
locomotion GO:0040011 237 0.014
regulation of dendrite development GO:0050773 59 0.013
positive regulation of transport GO:0051050 245 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
single organism cellular localization GO:1902580 102 0.013
positive regulation of cell motility GO:2000147 97 0.013
reproductive process GO:0022414 372 0.013
regulation of blood circulation GO:1903522 110 0.013
positive regulation of cell migration GO:0030335 96 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of hormone levels GO:0010817 187 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
cytokine production GO:0001816 61 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
chemical homeostasis GO:0048878 292 0.013
cellular cation homeostasis GO:0030003 180 0.013
response to insulin GO:0032868 133 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
response to biotic stimulus GO:0009607 226 0.013
neuron apoptotic process GO:0051402 88 0.012
regulation of secretion GO:0051046 224 0.012
regulation of transferase activity GO:0051338 123 0.012
muscle cell migration GO:0014812 36 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
regulation of cell motility GO:2000145 131 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
response to nicotine GO:0035094 51 0.012
negative regulation of molecular function GO:0044092 133 0.012
regeneration GO:0031099 163 0.012
organic acid transport GO:0015849 116 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
divalent inorganic cation transport GO:0072511 134 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
muscle contraction GO:0006936 88 0.012
peptide hormone secretion GO:0030072 84 0.012
dendrite development GO:0016358 72 0.012
salivary gland development GO:0007431 3 0.012
chromosome segregation GO:0007059 2 0.012
heart process GO:0003015 57 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of ion transport GO:0043270 94 0.012
neuronal action potential GO:0019228 35 0.012
cellular response to peptide GO:1901653 133 0.012
muscle organ development GO:0007517 50 0.012
tissue development GO:0009888 252 0.012
regulation of response to external stimulus GO:0032101 106 0.012
protein oligomerization GO:0051259 191 0.011
regulation of muscle system process GO:0090257 79 0.011
cardiac chamber development GO:0003205 1 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
regulation of homeostatic process GO:0032844 101 0.011
fatty acid metabolic process GO:0006631 99 0.011
sensory perception GO:0007600 101 0.011
reproduction GO:0000003 245 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
establishment of protein localization GO:0045184 141 0.011
spermatogenesis GO:0007283 99 0.011
response to catecholamine GO:0071869 16 0.011
dna metabolic process GO:0006259 96 0.011
regulation of neuron death GO:1901214 115 0.011
striated muscle tissue development GO:0014706 58 0.011
rhythmic process GO:0048511 156 0.011
axis specification GO:0009798 4 0.011
calcium ion transport GO:0006816 131 0.011
response to tumor necrosis factor GO:0034612 56 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
glycoprotein biosynthetic process GO:0009101 19 0.011
muscle tissue development GO:0060537 58 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
hormone secretion GO:0046879 115 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.010
small molecule biosynthetic process GO:0044283 124 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
vasculature development GO:0001944 70 0.010
regulation of tube size GO:0035150 89 0.010
wound healing GO:0042060 122 0.010
signal release GO:0023061 145 0.010
aromatic compound catabolic process GO:0019439 168 0.010
male gamete generation GO:0048232 99 0.010
cytoplasmic transport GO:0016482 115 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
circadian rhythm GO:0007623 88 0.010
regulation of peptide transport GO:0090087 87 0.010
positive regulation of transferase activity GO:0051347 81 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010

Cdc42ep3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.012
musculoskeletal system disease DOID:17 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011