Rattus norvegicus

56 known processes

Nisch

nischarin

(Aliases: I-1)

Nisch biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
synaptic growth at neuromuscular junction GO:0051124 1 0.174
regulation of cell development GO:0060284 263 0.150
neuron projection development GO:0031175 273 0.132
response to potassium ion GO:0035864 9 0.128
cellular component biogenesis GO:0044085 368 0.116
axon cargo transport GO:0008088 1 0.108
regulation of multicellular organismal development GO:2000026 376 0.101
regulation of cellular component movement GO:0051270 150 0.082
Mouse
cell motility GO:0048870 202 0.076
Mouse
synaptic transmission GO:0007268 235 0.074
positive regulation of multicellular organismal process GO:0051240 387 0.073
cellular component movement GO:0006928 248 0.066
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.052
single organism biosynthetic process GO:0044711 342 0.051
regulation of cell proliferation GO:0042127 359 0.051
neuron differentiation GO:0030182 368 0.051
axonogenesis GO:0007409 71 0.050
positive regulation of cellular component organization GO:0051130 200 0.049
regulation of nervous system development GO:0051960 264 0.049
chemical homeostasis GO:0048878 292 0.049
macromolecular complex assembly GO:0065003 273 0.049
programmed cell death GO:0012501 392 0.047
insulin like growth factor receptor signaling pathway GO:0048009 3 0.047
protein complex subunit organization GO:0071822 302 0.044
cellular response to lipid GO:0071396 201 0.044
positive regulation of cell differentiation GO:0045597 217 0.043
cellular component assembly GO:0022607 360 0.042
protein complex assembly GO:0006461 263 0.042
response to extracellular stimulus GO:0009991 380 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
organelle organization GO:0006996 266 0.040
Mouse
negative regulation of metabolic process GO:0009892 331 0.040
negative regulation of multicellular organismal process GO:0051241 203 0.039
response to inorganic substance GO:0010035 377 0.039
regulation of synapse assembly GO:0051963 15 0.039
catabolic process GO:0009056 351 0.038
cellular amine metabolic process GO:0044106 38 0.037
positive regulation of developmental process GO:0051094 283 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.035
ion transmembrane transport GO:0034220 365 0.035
neuron development GO:0048666 286 0.033
cell migration GO:0016477 197 0.033
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
growth GO:0040007 165 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.032
head development GO:0060322 247 0.032
transcription dna templated GO:0006351 377 0.032
regulation of neuron projection development GO:0010975 161 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.031
localization of cell GO:0051674 202 0.030
Mouse
regulation of cellular component organization GO:0051128 368 0.030
ras protein signal transduction GO:0007265 29 0.030
Mouse
heart contraction GO:0060047 57 0.029
regulation of cell differentiation GO:0045595 320 0.029
cellular homeostasis GO:0019725 252 0.029
cell cell signaling GO:0007267 335 0.029
positive regulation of cell proliferation GO:0008284 249 0.028
central nervous system development GO:0007417 311 0.028
cation homeostasis GO:0055080 195 0.028
nucleotide metabolic process GO:0009117 279 0.028
positive regulation of nervous system development GO:0051962 178 0.028
cell projection organization GO:0030030 302 0.028
macromolecular complex subunit organization GO:0043933 339 0.027
amine metabolic process GO:0009308 38 0.027
spindle organization GO:0007051 2 0.026
single organism cellular localization GO:1902580 102 0.026
protein dna complex disassembly GO:0032986 1 0.026
protein complex biogenesis GO:0070271 263 0.026
metal ion homeostasis GO:0055065 186 0.025
regulation of cell projection organization GO:0031344 175 0.025
response to metal ion GO:0010038 253 0.024
rna biosynthetic process GO:0032774 380 0.024
brain development GO:0007420 247 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
divalent inorganic cation homeostasis GO:0072507 165 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
positive regulation of gene expression GO:0010628 244 0.023
regulation of transmembrane transport GO:0034762 122 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
response to hydrogen peroxide GO:0042542 89 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
nucleoside phosphate biosynthetic process GO:1901293 102 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
cardiovascular system development GO:0072358 134 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
cell morphogenesis GO:0000902 142 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
response to oxygen levels GO:0070482 265 0.020
oxoacid metabolic process GO:0043436 290 0.020
cellular chemical homeostasis GO:0055082 247 0.020
response to growth factor GO:0070848 189 0.020
response to reactive oxygen species GO:0000302 120 0.020
positive regulation of cell projection organization GO:0031346 111 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
Mouse
response to nutrient levels GO:0031667 370 0.019
organic acid metabolic process GO:0006082 292 0.019
regulation of neurogenesis GO:0050767 247 0.019
cell fate determination GO:0001709 2 0.019
cell part morphogenesis GO:0032990 123 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
regulation of synapse structure and activity GO:0050803 21 0.018
positive regulation of signaling GO:0023056 270 0.018
positive regulation of cell motility GO:2000147 97 0.018
calcium ion homeostasis GO:0055074 162 0.017
glucose homeostasis GO:0042593 75 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
synapse organization GO:0050808 46 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
defense response GO:0006952 194 0.017
secretion by cell GO:0032940 248 0.017
intracellular signal transduction GO:0035556 314 0.017
Mouse
neuromuscular process GO:0050905 2 0.017
response to carbohydrate GO:0009743 183 0.017
protein localization to membrane GO:0072657 36 0.016
generation of precursor metabolites and energy GO:0006091 62 0.016
cellular ion homeostasis GO:0006873 184 0.016
cellular ketone metabolic process GO:0042180 51 0.016
single organism catabolic process GO:0044712 283 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
homeostatic process GO:0042592 331 0.015
developmental growth GO:0048589 100 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
ion homeostasis GO:0050801 212 0.015
regulation of phosphorylation GO:0042325 248 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
regulation of cell growth GO:0001558 85 0.015
regulation of molecular function GO:0065009 398 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
regulation of anatomical structure size GO:0090066 135 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of transporter activity GO:0032409 50 0.014
regulation of cell migration GO:0030334 128 0.014
Mouse
axon development GO:0061564 96 0.014
regulation of growth GO:0040008 105 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
regulation of neuron differentiation GO:0045664 208 0.014
cellular lipid metabolic process GO:0044255 208 0.014
transmembrane transport GO:0055085 412 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
epithelial cell proliferation GO:0050673 54 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
dendrite morphogenesis GO:0048813 43 0.013
glycerophospholipid metabolic process GO:0006650 47 0.013
negative regulation of cell death GO:0060548 229 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
response to peptide GO:1901652 292 0.013
positive regulation of locomotion GO:0040017 102 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
rna metabolic process GO:0016070 406 0.013
immune system process GO:0002376 204 0.013
rna localization GO:0006403 4 0.013
regulation of apoptotic process GO:0042981 335 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
nitrogen compound transport GO:0071705 229 0.012
tissue development GO:0009888 252 0.012
response to external biotic stimulus GO:0043207 221 0.012
regulation of rna metabolic process GO:0051252 391 0.012
organophosphate metabolic process GO:0019637 370 0.012
regulation of blood vessel endothelial cell migration GO:0043535 4 0.012
regulation of cell motility GO:2000145 131 0.012
Mouse
response to toxic substance GO:0009636 133 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
blood vessel development GO:0001568 69 0.012
regulation of membrane potential GO:0042391 110 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
apoptotic process GO:0006915 381 0.012
circulatory system development GO:0072359 134 0.012
molting cycle GO:0042303 3 0.012
negative regulation of innate immune response GO:0045824 4 0.012
positive regulation of cell development GO:0010720 176 0.012
cellular response to potassium ion GO:0035865 3 0.011
blood vessel morphogenesis GO:0048514 58 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
regulation of locomotion GO:0040012 148 0.011
Mouse
circadian rhythm GO:0007623 88 0.011
protein oligomerization GO:0051259 191 0.011
regulation of system process GO:0044057 208 0.011
regulation of metal ion transport GO:0010959 118 0.011
response to glucose GO:0009749 136 0.011
negative regulation of lipid biosynthetic process GO:0051055 2 0.011
negative regulation of gene expression GO:0010629 199 0.011
mitotic cell cycle process GO:1903047 35 0.011
mitotic spindle organization GO:0007052 2 0.011
vasculature development GO:0001944 70 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
calcium mediated signaling using intracellular calcium source GO:0035584 1 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
cytoplasmic transport GO:0016482 115 0.011
positive regulation of cell communication GO:0010647 271 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
regulation of neuron death GO:1901214 115 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
regulation of receptor activity GO:0010469 29 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
neuron projection guidance GO:0097485 24 0.010
hexose metabolic process GO:0019318 58 0.010
positive regulation of transport GO:0051050 245 0.010
cellular response to acid chemical GO:0071229 75 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
purine containing compound metabolic process GO:0072521 253 0.010
salivary gland development GO:0007431 3 0.010
secretion GO:0046903 307 0.010
cell growth GO:0016049 104 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
cellular response to monosaccharide stimulus GO:0071326 67 0.010
muscle cell proliferation GO:0033002 84 0.010
apoptotic mitochondrial changes GO:0008637 10 0.010
protein phosphorylation GO:0006468 345 0.010
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.010

Nisch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
cardiovascular system disease DOID:1287 0 0.038
central nervous system disease DOID:331 0 0.017
nervous system disease DOID:863 0 0.017
hypertension DOID:10763 0 0.011
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
essential hypertension DOID:10825 0 0.011