Rattus norvegicus

64 known processes

Ptma

prothymosin alpha

Ptma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell type specific apoptotic process GO:0097285 134 0.501
cell migration GO:0016477 197 0.410
positive regulation of cellular biosynthetic process GO:0031328 295 0.361
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.322
actin filament based process GO:0030029 86 0.290
negative regulation of rna metabolic process GO:0051253 123 0.285
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.274
rna metabolic process GO:0016070 406 0.236
positive regulation of gene expression GO:0010628 244 0.208
nucleic acid templated transcription GO:0097659 379 0.203
negative regulation of biosynthetic process GO:0009890 168 0.201
regulation of mesenchymal cell proliferation GO:0010464 4 0.195
actin cytoskeleton organization GO:0030036 73 0.190
cytoskeleton organization GO:0007010 111 0.188
positive regulation of neurogenesis GO:0050769 165 0.182
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.175
brain development GO:0007420 247 0.167
head development GO:0060322 247 0.161
central nervous system development GO:0007417 311 0.155
positive regulation of biosynthetic process GO:0009891 319 0.155
mesenchymal cell proliferation GO:0010463 4 0.147
negative regulation of cellular biosynthetic process GO:0031327 161 0.147
cell cycle GO:0007049 101 0.142
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.136
negative regulation of rna splicing GO:0033119 3 0.135
regulation of rna metabolic process GO:0051252 391 0.135
organelle organization GO:0006996 266 0.134
regulation of cell development GO:0060284 263 0.130
rna biosynthetic process GO:0032774 380 0.128
cell motility GO:0048870 202 0.119
organ regeneration GO:0031100 101 0.116
multi organism reproductive process GO:0044703 262 0.116
dna conformation change GO:0071103 10 0.116
regulation of nucleic acid templated transcription GO:1903506 380 0.114
regulation of multicellular organismal development GO:2000026 376 0.113
regulation of apoptotic process GO:0042981 335 0.113
positive regulation of actin filament polymerization GO:0030838 5 0.109
taxis GO:0042330 67 0.103
negative regulation of macromolecule metabolic process GO:0010605 260 0.100
striated muscle cell development GO:0055002 26 0.099
negative regulation of cellular metabolic process GO:0031324 281 0.097
negative regulation of gene expression GO:0010629 199 0.093
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.093
multicellular organism reproduction GO:0032504 233 0.092
positive regulation of nucleic acid templated transcription GO:1903508 197 0.090
neuron projection development GO:0031175 273 0.088
positive regulation of catalytic activity GO:0043085 184 0.088
single organism organelle organization GO:1902589 180 0.087
tissue development GO:0009888 252 0.086
chemotaxis GO:0006935 66 0.086
cellular component biogenesis GO:0044085 368 0.085
positive regulation of cell differentiation GO:0045597 217 0.084
neuron development GO:0048666 286 0.083
transcription from rna polymerase ii promoter GO:0006366 252 0.082
cellular component movement GO:0006928 248 0.081
hair cycle process GO:0022405 2 0.080
localization of cell GO:0051674 202 0.078
regulation of cell proliferation GO:0042127 359 0.077
response to other organism GO:0051707 220 0.077
reproduction GO:0000003 245 0.076
sexual reproduction GO:0019953 148 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.075
striated muscle tissue development GO:0014706 58 0.075
response to insulin GO:0032868 133 0.074
cellular protein localization GO:0034613 122 0.073
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.071
inflammatory response GO:0006954 150 0.070
cell projection organization GO:0030030 302 0.068
negative regulation of transcription dna templated GO:0045892 116 0.068
positive regulation of cellular component movement GO:0051272 102 0.065
posttranscriptional regulation of gene expression GO:0010608 37 0.065
arp2 3 complex mediated actin nucleation GO:0034314 2 0.065
response to peptide hormone GO:0043434 278 0.065
circadian rhythm GO:0007623 88 0.064
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.059
regulation of rna biosynthetic process GO:2001141 381 0.059
reproductive process GO:0022414 372 0.057
positive regulation of transcription dna templated GO:0045893 197 0.057
positive regulation of cell proliferation GO:0008284 249 0.057
positive regulation of rna biosynthetic process GO:1902680 197 0.055
immune system process GO:0002376 204 0.053
cellular component morphogenesis GO:0032989 155 0.053
aging GO:0007568 241 0.052
nitrogen compound transport GO:0071705 229 0.052
regulation of translation GO:0006417 27 0.052
cellular response to hormone stimulus GO:0032870 247 0.050
response to decreased oxygen levels GO:0036293 237 0.050
dna metabolic process GO:0006259 96 0.049
regulation of dna metabolic process GO:0051052 60 0.048
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.048
macromolecule localization GO:0033036 252 0.047
neuron differentiation GO:0030182 368 0.046
response to biotic stimulus GO:0009607 226 0.045
positive regulation of neuron differentiation GO:0045666 126 0.045
muscle structure development GO:0061061 87 0.044
response to external biotic stimulus GO:0043207 221 0.044
positive regulation of response to external stimulus GO:0032103 51 0.043
programmed cell death GO:0012501 392 0.043
regulation of actin filament based process GO:0032970 42 0.043
negative regulation of metabolic process GO:0009892 331 0.043
negative regulation of rna biosynthetic process GO:1902679 118 0.042
negative regulation of nucleic acid templated transcription GO:1903507 117 0.042
response to interleukin 1 GO:0070555 55 0.042
negative regulation of mrna splicing via spliceosome GO:0048025 2 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
multicellular organismal reproductive process GO:0048609 233 0.041
response to extracellular stimulus GO:0009991 380 0.041
positive regulation of cell migration GO:0030335 96 0.040
regeneration GO:0031099 163 0.040
positive regulation of apoptotic process GO:0043065 154 0.040
positive regulation of developmental process GO:0051094 283 0.039
protein localization to organelle GO:0033365 57 0.039
establishment of protein localization GO:0045184 141 0.039
protein localization GO:0008104 191 0.039
transcription dna templated GO:0006351 377 0.039
response to cytokine GO:0034097 215 0.039
regulation of programmed cell death GO:0043067 341 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.037
multicellular organism growth GO:0035264 1 0.037
regulation of anatomical structure size GO:0090066 135 0.036
positive regulation of cell death GO:0010942 184 0.036
apoptotic process GO:0006915 381 0.036
response to glucose GO:0009749 136 0.036
regulation of endocytosis GO:0030100 42 0.035
regulation of neuron projection development GO:0010975 161 0.035
positive regulation of behavior GO:0048520 38 0.034
circulatory system development GO:0072359 134 0.034
behavior GO:0007610 205 0.033
response to carbohydrate GO:0009743 183 0.033
positive regulation of rna metabolic process GO:0051254 203 0.033
regulation of cell migration GO:0030334 128 0.032
neurotransmitter uptake GO:0001504 3 0.032
motor neuron axon guidance GO:0008045 1 0.032
regulation of organelle organization GO:0033043 80 0.032
locomotion GO:0040011 237 0.032
protein targeting GO:0006605 61 0.032
actin filament depolymerization GO:0030042 3 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.031
growth GO:0040007 165 0.031
muscle cell development GO:0055001 26 0.030
myeloid cell apoptotic process GO:0033028 6 0.030
neurological system process GO:0050877 219 0.030
cell junction organization GO:0034330 21 0.030
protein complex assembly GO:0006461 263 0.029
neuron apoptotic process GO:0051402 88 0.029
developmental process involved in reproduction GO:0003006 159 0.029
receptor metabolic process GO:0043112 18 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.028
immune response GO:0006955 104 0.028
mrna stabilization GO:0048255 2 0.028
cellular response to cytokine stimulus GO:0071345 127 0.028
negative regulation of signaling GO:0023057 157 0.028
rna splicing GO:0008380 11 0.027
cellular component assembly GO:0022607 360 0.027
fertilization GO:0009566 3 0.027
skeletal muscle organ development GO:0060538 33 0.027
protein transport GO:0015031 132 0.027
positive regulation of smooth muscle cell migration GO:0014911 27 0.027
regulation of neuron differentiation GO:0045664 208 0.027
single organism reproductive process GO:0044702 297 0.026
regulation of immune system process GO:0002682 123 0.026
nucleobase containing compound catabolic process GO:0034655 152 0.026
regulation of actin filament length GO:0030832 12 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
response to peptide GO:1901652 292 0.025
cell cell signaling GO:0007267 335 0.025
cellular response to lipid GO:0071396 201 0.025
spermatogenesis GO:0007283 99 0.025
regulation of response to wounding GO:1903034 69 0.025
regulation of response to external stimulus GO:0032101 106 0.025
positive regulation of nervous system development GO:0051962 178 0.025
cellular response to insulin stimulus GO:0032869 81 0.024
male gamete generation GO:0048232 99 0.024
positive regulation of cell motility GO:2000147 97 0.024
macromolecular complex assembly GO:0065003 273 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
homeostatic process GO:0042592 331 0.023
regulation of meiotic cell cycle GO:0051445 3 0.023
regulation of cell differentiation GO:0045595 320 0.022
regulation of molecular function GO:0065009 398 0.022
liver development GO:0001889 90 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
signal release GO:0023061 145 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
regulation of ion transport GO:0043269 245 0.021
skeletal muscle tissue development GO:0007519 31 0.021
actin nucleation GO:0045010 2 0.021
mrna metabolic process GO:0016071 20 0.021
calcium ion homeostasis GO:0055074 162 0.021
hemidesmosome assembly GO:0031581 1 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
regulation of response to stress GO:0080134 126 0.021
histamine secretion involved in inflammatory response GO:0002441 3 0.020
gonad development GO:0008406 104 0.020
regulation of cellular component movement GO:0051270 150 0.020
negative regulation of transport GO:0051051 136 0.019
intracellular protein transport GO:0006886 79 0.019
smooth muscle cell migration GO:0014909 36 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
meiotic chromosome segregation GO:0045132 1 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
response to hexose GO:0009746 144 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
single fertilization GO:0007338 3 0.019
intracellular signal transduction GO:0035556 314 0.019
muscle tissue development GO:0060537 58 0.019
cell chemotaxis GO:0060326 31 0.018
neuron death GO:0070997 127 0.018
cation transport GO:0006812 382 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
neuromuscular process GO:0050905 2 0.018
cellular catabolic process GO:0044248 295 0.018
protein polymerization GO:0051258 22 0.018
meiotic cell cycle process GO:1903046 3 0.018
response to interferon gamma GO:0034341 20 0.018
regulation of signal transduction GO:0009966 318 0.018
cell projection assembly GO:0030031 21 0.018
regulation of chemotaxis GO:0050920 29 0.017
cellular macromolecular complex assembly GO:0034622 58 0.017
reproductive system development GO:0061458 128 0.017
nucleotide catabolic process GO:0009166 139 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
actin myosin filament sliding GO:0033275 2 0.017
positive regulation of locomotion GO:0040017 102 0.017
epithelial cell differentiation GO:0030855 71 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
gland development GO:0048732 155 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
protein complex biogenesis GO:0070271 263 0.017
cell junction assembly GO:0034329 18 0.017
chemical homeostasis GO:0048878 292 0.016
response to monosaccharide GO:0034284 159 0.016
regulation of transcription dna templated GO:0006355 374 0.016
cellular macromolecule localization GO:0070727 122 0.016
positive regulation of molecular function GO:0044093 230 0.016
regulation of locomotion GO:0040012 148 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
positive chemotaxis GO:0050918 9 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
cell cycle process GO:0022402 57 0.016
protein oligomerization GO:0051259 191 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
protein complex subunit organization GO:0071822 302 0.016
positive regulation of cytoskeleton organization GO:0051495 26 0.016
histamine production involved in inflammatory response GO:0002349 3 0.016
regulation of cell activation GO:0050865 50 0.015
regulation of growth GO:0040008 105 0.015
translation GO:0006412 35 0.015
regulation of cytoskeleton organization GO:0051493 49 0.015
regulation of muscle tissue development GO:1901861 25 0.015
rhythmic process GO:0048511 156 0.015
amine metabolic process GO:0009308 38 0.015
muscle cell differentiation GO:0042692 52 0.015
striated muscle cell differentiation GO:0051146 39 0.015
regulation of body fluid levels GO:0050878 90 0.015
heterocycle catabolic process GO:0046700 167 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
skin morphogenesis GO:0043589 2 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
positive regulation of dna metabolic process GO:0051054 39 0.014
regulation of protein polymerization GO:0032271 19 0.014
regulation of muscle cell differentiation GO:0051147 22 0.014
cellular ion homeostasis GO:0006873 184 0.014
response to wounding GO:0009611 254 0.014
protein homooligomerization GO:0051260 91 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
dna replication GO:0006260 37 0.014
actin filament polymerization GO:0030041 11 0.014
eye morphogenesis GO:0048592 4 0.014
regulation of membrane potential GO:0042391 110 0.014
cellular amine metabolic process GO:0044106 38 0.013
reproductive structure development GO:0048608 128 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
vasculature development GO:0001944 70 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
cell part morphogenesis GO:0032990 123 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
rna stabilization GO:0043489 2 0.013
regulation of inflammatory response GO:0050727 48 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
cell projection morphogenesis GO:0048858 123 0.012
regulation of actin polymerization or depolymerization GO:0008064 12 0.012
defense response GO:0006952 194 0.012
innate immune response GO:0045087 35 0.012
response to bacterium GO:0009617 200 0.012
endocytosis GO:0006897 84 0.012
actin polymerization or depolymerization GO:0008154 14 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
reproductive behavior GO:0019098 10 0.011
rna localization GO:0006403 4 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
catabolic process GO:0009056 351 0.011
alternative mrna splicing via spliceosome GO:0000380 4 0.011
response to nutrient levels GO:0031667 370 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
regulation of mrna stability GO:0043488 3 0.011
production of molecular mediator involved in inflammatory response GO:0002532 5 0.011
regulation of muscle organ development GO:0048634 26 0.011
axonogenesis GO:0007409 71 0.011
sex differentiation GO:0007548 113 0.011
immune effector process GO:0002252 53 0.011
actin filament organization GO:0007015 42 0.011
lipid metabolic process GO:0006629 283 0.011
regulation of neuron death GO:1901214 115 0.011
positive regulation of cell development GO:0010720 176 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
activation of phospholipase d activity GO:0031584 2 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
sex determination GO:0007530 2 0.010
developmental growth GO:0048589 100 0.010
regulation of microtubule based process GO:0032886 14 0.010
negative regulation of protein modification by small protein conjugation or removal GO:1903321 4 0.010
response to lipopolysaccharide GO:0032496 191 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
dendrite development GO:0016358 72 0.010
regulation of smooth muscle cell migration GO:0014910 36 0.010
chemosensory behavior GO:0007635 2 0.010
regulation of mrna processing GO:0050684 5 0.010
hair follicle development GO:0001942 2 0.010

Ptma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org