Rattus norvegicus

73 known processes

Mat1a

methionine adenosyltransferase I, alpha

(Aliases: SAS,MGC108563,SADE,AdoMet)

Mat1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 71 0.284
carboxylic acid metabolic process GO:0019752 289 0.231
response to nutrient GO:0007584 248 0.176
serine family amino acid metabolic process GO:0009069 12 0.168
aromatic amino acid family catabolic process GO:0009074 7 0.133
response to inorganic substance GO:0010035 377 0.129
gland development GO:0048732 155 0.112
regulation of apoptotic process GO:0042981 335 0.106
alpha amino acid catabolic process GO:1901606 20 0.101
organic acid metabolic process GO:0006082 292 0.099
catabolic process GO:0009056 351 0.094
apoptotic process GO:0006915 381 0.093
reproductive process GO:0022414 372 0.081
cellular component assembly GO:0022607 360 0.071
oxoacid metabolic process GO:0043436 290 0.069
defense response GO:0006952 194 0.062
cellular amino acid metabolic process GO:0006520 107 0.062
coenzyme metabolic process GO:0006732 86 0.060
hepaticobiliary system development GO:0061008 90 0.057
glycine metabolic process GO:0006544 7 0.057
reproductive system development GO:0061458 128 0.055
cell type specific apoptotic process GO:0097285 134 0.054
monocarboxylic acid metabolic process GO:0032787 152 0.053
protein complex assembly GO:0006461 263 0.052
cellular response to oxygen containing compound GO:1901701 386 0.051
regulation of programmed cell death GO:0043067 341 0.050
protein oligomerization GO:0051259 191 0.049
response to peptide hormone GO:0043434 278 0.049
cofactor metabolic process GO:0051186 95 0.049
programmed cell death GO:0012501 392 0.048
response to metal ion GO:0010038 253 0.047
chemical homeostasis GO:0048878 292 0.046
positive regulation of cell death GO:0010942 184 0.046
negative regulation of gene expression GO:0010629 199 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.045
response to peptide GO:1901652 292 0.045
cation transmembrane transport GO:0098655 263 0.043
response to extracellular stimulus GO:0009991 380 0.043
proteolysis GO:0006508 175 0.042
response to purine containing compound GO:0014074 126 0.042
regeneration GO:0031099 163 0.041
positive regulation of programmed cell death GO:0043068 157 0.041
response to acid chemical GO:0001101 222 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
fatty acid metabolic process GO:0006631 99 0.038
urea cycle GO:0000050 5 0.038
single organism catabolic process GO:0044712 283 0.037
organic acid biosynthetic process GO:0016053 83 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
liver development GO:0001889 90 0.035
single organism reproductive process GO:0044702 297 0.033
regulation of cellular component organization GO:0051128 368 0.033
central nervous system development GO:0007417 311 0.032
cellular catabolic process GO:0044248 295 0.031
cellular response to stress GO:0033554 269 0.031
heart morphogenesis GO:0003007 3 0.031
cellular amino acid biosynthetic process GO:0008652 32 0.030
positive regulation of apoptotic process GO:0043065 154 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
response to nutrient levels GO:0031667 370 0.030
small molecule catabolic process GO:0044282 59 0.029
acylglycerol metabolic process GO:0006639 21 0.029
response to oxygen levels GO:0070482 265 0.029
response to hexose GO:0009746 144 0.029
response to estrogen GO:0043627 232 0.028
cellular amino acid catabolic process GO:0009063 21 0.028
macromolecular complex assembly GO:0065003 273 0.028
regulation of nervous system development GO:0051960 264 0.028
protein complex subunit organization GO:0071822 302 0.027
neuron projection development GO:0031175 273 0.027
organic substance catabolic process GO:1901575 316 0.027
serine family amino acid biosynthetic process GO:0009070 4 0.026
response to ionizing radiation GO:0010212 59 0.026
positive regulation of transport GO:0051050 245 0.026
regulation of cell development GO:0060284 263 0.026
pteridine containing compound metabolic process GO:0042558 14 0.025
reproductive structure development GO:0048608 128 0.025
secretion GO:0046903 307 0.025
positive regulation of peptide secretion GO:0002793 52 0.025
regulation of molecular function GO:0065009 398 0.025
circulatory system development GO:0072359 134 0.024
response to insulin GO:0032868 133 0.024
cellular response to peptide GO:1901653 133 0.024
carboxylic acid catabolic process GO:0046395 49 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
protein complex biogenesis GO:0070271 263 0.023
regulation of system process GO:0044057 208 0.023
reactive oxygen species metabolic process GO:0072593 37 0.023
multi multicellular organism process GO:0044706 138 0.023
cellular component biogenesis GO:0044085 368 0.022
female pregnancy GO:0007565 122 0.022
neutral lipid metabolic process GO:0006638 21 0.022
response to cytokine GO:0034097 215 0.021
response to decreased oxygen levels GO:0036293 237 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
protein phosphorylation GO:0006468 345 0.021
reproduction GO:0000003 245 0.021
regulation of cell differentiation GO:0045595 320 0.021
regulation of defense response GO:0031347 68 0.020
inflammatory response GO:0006954 150 0.020
organic acid catabolic process GO:0016054 49 0.020
peptide transport GO:0015833 97 0.020
response to glucose GO:0009749 136 0.020
cardiac chamber development GO:0003205 1 0.020
response to oxidative stress GO:0006979 186 0.020
protein homooligomerization GO:0051260 91 0.020
regulation of peptide transport GO:0090087 87 0.020
response to wounding GO:0009611 254 0.020
response to radiation GO:0009314 137 0.019
regulation of neurogenesis GO:0050767 247 0.019
alpha amino acid biosynthetic process GO:1901607 23 0.019
vesicle mediated transport GO:0016192 181 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
negative regulation of innate immune response GO:0045824 4 0.019
gastrulation GO:0007369 2 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
regulation of response to stress GO:0080134 126 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
circulatory system process GO:0003013 183 0.018
response to interleukin 1 GO:0070555 55 0.018
regulation of cell proliferation GO:0042127 359 0.018
neurological system process GO:0050877 219 0.018
sulfur amino acid metabolic process GO:0000096 9 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
positive regulation of blood circulation GO:1903524 65 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
macromolecule localization GO:0033036 252 0.017
transmission of nerve impulse GO:0019226 42 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
cellular chemical homeostasis GO:0055082 247 0.016
secretion by cell GO:0032940 248 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
neuron differentiation GO:0030182 368 0.016
cellular homeostasis GO:0019725 252 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
negative regulation of metabolic process GO:0009892 331 0.016
regulation of hydrolase activity GO:0051336 143 0.016
response to vitamin GO:0033273 131 0.016
response to growth factor GO:0070848 189 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
cellular amine metabolic process GO:0044106 38 0.016
carbohydrate metabolic process GO:0005975 130 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
regulation of cell projection organization GO:0031344 175 0.016
heart development GO:0007507 72 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
cellular response to endogenous stimulus GO:0071495 377 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
developmental process involved in reproduction GO:0003006 159 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
aromatic amino acid family metabolic process GO:0009072 9 0.015
cellular ketone metabolic process GO:0042180 51 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
muscle cell apoptotic process GO:0010657 30 0.015
rna biosynthetic process GO:0032774 380 0.015
urea metabolic process GO:0019627 5 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
response to carbohydrate GO:0009743 183 0.015
amine metabolic process GO:0009308 38 0.015
response to monosaccharide GO:0034284 159 0.015
cellular response to insulin stimulus GO:0032869 81 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
aging GO:0007568 241 0.014
brain development GO:0007420 247 0.014
acute inflammatory response GO:0002526 58 0.014
regulation of rna metabolic process GO:0051252 391 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
homeostatic process GO:0042592 331 0.014
response to corticosteroid GO:0031960 235 0.014
oxidation reduction process GO:0055114 304 0.014
sulfur compound metabolic process GO:0006790 70 0.014
peptide secretion GO:0002790 86 0.014
establishment of tissue polarity GO:0007164 2 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
cell projection organization GO:0030030 302 0.014
cellular macromolecule localization GO:0070727 122 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
lipid storage GO:0019915 1 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
response to temperature stimulus GO:0009266 94 0.013
establishment of protein localization GO:0045184 141 0.013
response to ketone GO:1901654 182 0.013
acetyl coa metabolic process GO:0006084 17 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of gene expression GO:0010628 244 0.013
regulation of protein metabolic process GO:0051246 289 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
tetrahydrofolate metabolic process GO:0046653 9 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
triglyceride metabolic process GO:0006641 21 0.012
response to organophosphorus GO:0046683 102 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
protein transport GO:0015031 132 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
limb morphogenesis GO:0035108 4 0.012
cardiovascular system development GO:0072358 134 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of phosphorylation GO:0042325 248 0.012
tissue development GO:0009888 252 0.012
single organism biosynthetic process GO:0044711 342 0.012
response to retinoic acid GO:0032526 63 0.012
gonad development GO:0008406 104 0.012
blood circulation GO:0008015 183 0.012
regulation of muscle cell apoptotic process GO:0010660 26 0.012
organelle organization GO:0006996 266 0.012
regulation of tube size GO:0035150 89 0.011
positive regulation of extracellular matrix organization GO:1903055 4 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
glucose metabolic process GO:0006006 52 0.011
protein maturation GO:0051604 68 0.011
transcription dna templated GO:0006351 377 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
organophosphate metabolic process GO:0019637 370 0.011
regulation of neuron differentiation GO:0045664 208 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
fertilization GO:0009566 3 0.011
response to calcium ion GO:0051592 59 0.011
neuron development GO:0048666 286 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
negative regulation of cell death GO:0060548 229 0.011
response to increased oxygen levels GO:0036296 45 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
regulation of secretion GO:0051046 224 0.011
growth GO:0040007 165 0.011
midgut development GO:0007494 13 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of neuron projection development GO:0010975 161 0.011
immune system process GO:0002376 204 0.011
regulation of protein phosphorylation GO:0001932 183 0.010
regulation of body fluid levels GO:0050878 90 0.010
regulation of phosphate metabolic process GO:0019220 349 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
axis specification GO:0009798 4 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
monosaccharide metabolic process GO:0005996 61 0.010
regulation of peptide secretion GO:0002791 82 0.010
cellular component morphogenesis GO:0032989 155 0.010
regulation of transcription dna templated GO:0006355 374 0.010
neuronal action potential GO:0019228 35 0.010
mesoderm development GO:0007498 2 0.010
muscle contraction GO:0006936 88 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
organ regeneration GO:0031100 101 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
response to ethanol GO:0045471 162 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010

Mat1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.020
amino acid metabolic disorder DOID:9252 0 0.010