Rattus norvegicus

0 known processes

Tbc1d2b

TBC1 domain family, member 2B

(Aliases: RGD1307436)

Tbc1d2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron death GO:0070997 127 0.159
regulation of nucleic acid templated transcription GO:1903506 380 0.135
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.116
cell type specific apoptotic process GO:0097285 134 0.114
nucleic acid templated transcription GO:0097659 379 0.111
circulatory system process GO:0003013 183 0.101
apoptotic process GO:0006915 381 0.084
regulation of neuron death GO:1901214 115 0.081
single organism biosynthetic process GO:0044711 342 0.081
transcription dna templated GO:0006351 377 0.074
regulation of apoptotic process GO:0042981 335 0.069
regulation of phosphorus metabolic process GO:0051174 349 0.066
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.062
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.059
programmed cell death GO:0012501 392 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
intracellular signal transduction GO:0035556 314 0.054
cellular response to endogenous stimulus GO:0071495 377 0.053
organic substance catabolic process GO:1901575 316 0.050
organic acid metabolic process GO:0006082 292 0.048
regulation of cell proliferation GO:0042127 359 0.048
positive regulation of cellular biosynthetic process GO:0031328 295 0.047
organophosphate metabolic process GO:0019637 370 0.046
positive regulation of transcription dna templated GO:0045893 197 0.046
positive regulation of biosynthetic process GO:0009891 319 0.045
regulation of phosphate metabolic process GO:0019220 349 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
rna metabolic process GO:0016070 406 0.044
negative regulation of cell death GO:0060548 229 0.043
positive regulation of phosphate metabolic process GO:0045937 262 0.043
positive regulation of gene expression GO:0010628 244 0.042
small gtpase mediated signal transduction GO:0007264 36 0.039
regeneration GO:0031099 163 0.039
rna biosynthetic process GO:0032774 380 0.039
regulation of cell differentiation GO:0045595 320 0.038
cellular component movement GO:0006928 248 0.038
positive regulation of rna biosynthetic process GO:1902680 197 0.038
regulation of neuron apoptotic process GO:0043523 83 0.037
negative regulation of apoptotic process GO:0043066 181 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.037
carboxylic acid metabolic process GO:0019752 289 0.036
positive regulation of neurogenesis GO:0050769 165 0.035
regulation of programmed cell death GO:0043067 341 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
oxoacid metabolic process GO:0043436 290 0.035
positive regulation of cell differentiation GO:0045597 217 0.035
positive regulation of hydrolase activity GO:0051345 86 0.034
response to peptide GO:1901652 292 0.033
negative regulation of programmed cell death GO:0043069 183 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
regulation of neuron differentiation GO:0045664 208 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
regulation of molecular function GO:0065009 398 0.033
regulation of cellular component movement GO:0051270 150 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
nucleotide metabolic process GO:0009117 279 0.032
cellular ketone metabolic process GO:0042180 51 0.031
negative regulation of rna metabolic process GO:0051253 123 0.031
amine metabolic process GO:0009308 38 0.031
cellular amine metabolic process GO:0044106 38 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.030
negative regulation of biosynthetic process GO:0009890 168 0.030
cellular response to cytokine stimulus GO:0071345 127 0.029
neuron apoptotic process GO:0051402 88 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
regulation of catalytic activity GO:0050790 304 0.029
regulation of cell projection organization GO:0031344 175 0.029
protein phosphorylation GO:0006468 345 0.029
reproduction GO:0000003 245 0.028
response to hypoxia GO:0001666 231 0.028
regulation of nervous system development GO:0051960 264 0.028
response to oxygen levels GO:0070482 265 0.028
neuron projection development GO:0031175 273 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
positive regulation of molecular function GO:0044093 230 0.027
ras protein signal transduction GO:0007265 29 0.027
positive regulation of rna metabolic process GO:0051254 203 0.026
positive regulation of cell projection organization GO:0031346 111 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
positive regulation of nervous system development GO:0051962 178 0.026
positive regulation of cell communication GO:0010647 271 0.026
regulation of multicellular organismal development GO:2000026 376 0.025
regulation of cellular localization GO:0060341 263 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
regulation of rna metabolic process GO:0051252 391 0.025
motor neuron axon guidance GO:0008045 1 0.025
nucleoside phosphate biosynthetic process GO:1901293 102 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
positive regulation of nucleotide metabolic process GO:0045981 91 0.024
response to inorganic substance GO:0010035 377 0.024
blood circulation GO:0008015 183 0.024
single organism reproductive process GO:0044702 297 0.024
anatomical structure morphogenesis GO:0009653 298 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
negative regulation of metabolic process GO:0009892 331 0.023
sexual reproduction GO:0019953 148 0.023
response to amino acid GO:0043200 75 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
response to extracellular stimulus GO:0009991 380 0.022
tumor necrosis factor production GO:0032640 13 0.022
positive regulation of developmental process GO:0051094 283 0.022
neuron differentiation GO:0030182 368 0.022
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.022
synaptic transmission GO:0007268 235 0.022
negative regulation of gene expression GO:0010629 199 0.022
regulation of cytokine production GO:0001817 56 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.021
regulation of cell development GO:0060284 263 0.021
lipid metabolic process GO:0006629 283 0.021
multicellular organism reproduction GO:0032504 233 0.021
response to decreased oxygen levels GO:0036293 237 0.021
response to biotic stimulus GO:0009607 226 0.021
response to insulin GO:0032868 133 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
regulation of hydrolase activity GO:0051336 143 0.021
purine containing compound metabolic process GO:0072521 253 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
rhythmic process GO:0048511 156 0.020
homeostatic process GO:0042592 331 0.020
vasculogenesis GO:0001570 3 0.020
regulation of signal transduction GO:0009966 318 0.020
single organism catabolic process GO:0044712 283 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
oxidation reduction process GO:0055114 304 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
carbohydrate metabolic process GO:0005975 130 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
behavior GO:0007610 205 0.019
regulation of neurogenesis GO:0050767 247 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
protein complex subunit organization GO:0071822 302 0.019
transmembrane transport GO:0055085 412 0.019
cellular component morphogenesis GO:0032989 155 0.018
positive regulation of cell death GO:0010942 184 0.018
b cell differentiation GO:0030183 2 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
response to growth factor GO:0070848 189 0.018
glycogen metabolic process GO:0005977 23 0.017
coronary vasculature morphogenesis GO:0060977 3 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
negative regulation of neuron apoptotic process GO:0043524 45 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
mapk cascade GO:0000165 140 0.017
negative regulation of signaling GO:0023057 157 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
cellular protein complex assembly GO:0043623 44 0.017
neuron projection morphogenesis GO:0048812 122 0.017
response to camp GO:0051591 91 0.017
cellular macromolecule localization GO:0070727 122 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
heterocycle catabolic process GO:0046700 167 0.017
cell morphogenesis GO:0000902 142 0.017
regulation of system process GO:0044057 208 0.017
positive regulation of signaling GO:0023056 270 0.017
negative regulation of developmental process GO:0051093 125 0.017
cellular component assembly GO:0022607 360 0.017
reproductive process GO:0022414 372 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
aromatic compound catabolic process GO:0019439 168 0.016
regulation of protein metabolic process GO:0051246 289 0.016
cellular response to stress GO:0033554 269 0.016
response to purine containing compound GO:0014074 126 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
cell cell signaling GO:0007267 335 0.016
axonogenesis GO:0007409 71 0.015
multi organism reproductive process GO:0044703 262 0.015
regulation of transcription dna templated GO:0006355 374 0.015
single organism organelle organization GO:1902589 180 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
response to organophosphorus GO:0046683 102 0.015
negative regulation of transport GO:0051051 136 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
neuron development GO:0048666 286 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
epithelial cell differentiation GO:0030855 71 0.015
cell activation GO:0001775 97 0.015
intracellular transport GO:0046907 185 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
membrane organization GO:0061024 94 0.015
cation transmembrane transport GO:0098655 263 0.014
peptidyl amino acid modification GO:0018193 126 0.014
regulation of response to wounding GO:1903034 69 0.014
cellular response to lipid GO:0071396 201 0.014
cellular catabolic process GO:0044248 295 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
regulation of nucleotide biosynthetic process GO:0030808 47 0.014
heart morphogenesis GO:0003007 3 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of metanephros development GO:0072215 4 0.014
response to estradiol GO:0032355 164 0.014
negative regulation of neuron death GO:1901215 69 0.014
rho protein signal transduction GO:0007266 11 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
cytokine biosynthetic process GO:0042089 3 0.014
protein maturation GO:0051604 68 0.013
response to hydrogen peroxide GO:0042542 89 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
cell projection organization GO:0030030 302 0.013
leukocyte differentiation GO:0002521 30 0.013
regulation of anatomical structure size GO:0090066 135 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
response to reactive oxygen species GO:0000302 120 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
response to estrogen GO:0043627 232 0.013
muscle system process GO:0003012 115 0.013
catabolic process GO:0009056 351 0.013
ion transmembrane transport GO:0034220 365 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
positive regulation of endothelial cell migration GO:0010595 4 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
cardiac ventricle development GO:0003231 1 0.013
cellular component biogenesis GO:0044085 368 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
cellular chemical homeostasis GO:0055082 247 0.013
proteolysis GO:0006508 175 0.013
growth GO:0040007 165 0.012
cellular homeostasis GO:0019725 252 0.012
epithelium development GO:0060429 96 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
vesicle mediated transport GO:0016192 181 0.012
response to peptide hormone GO:0043434 278 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
inflammatory response GO:0006954 150 0.012
sequestering of metal ion GO:0051238 9 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
organelle organization GO:0006996 266 0.012
regulation of mapk cascade GO:0043408 116 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
sex differentiation GO:0007548 113 0.012
regulation of protein modification process GO:0031399 194 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cellular protein localization GO:0034613 122 0.012
negative regulation of cell communication GO:0010648 158 0.012
cytokine production GO:0001816 61 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
nuclear transport GO:0051169 49 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
comma shaped body morphogenesis GO:0072049 2 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cell differentiation involved in kidney development GO:0061005 4 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
establishment of protein localization to organelle GO:0072594 44 0.011
positive regulation of blood coagulation GO:0030194 4 0.011
jak stat cascade GO:0007259 26 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
calcium ion homeostasis GO:0055074 162 0.011
negative regulation of osteoblast differentiation GO:0045668 2 0.011
regulation of cellular component organization GO:0051128 368 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
response to carbohydrate GO:0009743 183 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of catabolic process GO:0009894 113 0.011
heart process GO:0003015 57 0.011
response to other organism GO:0051707 220 0.011
regulation of body fluid levels GO:0050878 90 0.011
cell projection morphogenesis GO:0048858 123 0.011
ossification GO:0001503 70 0.011
stress activated mapk cascade GO:0051403 35 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cell proliferation involved in metanephros development GO:0072203 2 0.011
regulation of tumor necrosis factor production GO:0032680 13 0.011
macromolecule localization GO:0033036 252 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of embryonic development GO:0045995 2 0.011
response to epidermal growth factor GO:0070849 18 0.011
immune system development GO:0002520 41 0.011
aging GO:0007568 241 0.011
cellular ion homeostasis GO:0006873 184 0.011
cell growth GO:0016049 104 0.011
kidney development GO:0001822 67 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
vascular process in circulatory system GO:0003018 96 0.011
regulation of cellular response to stress GO:0080135 49 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
axon development GO:0061564 96 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
defense response to gram positive bacterium GO:0050830 2 0.010
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.010
localization of cell GO:0051674 202 0.010
male gamete generation GO:0048232 99 0.010
axis specification GO:0009798 4 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
regulation of establishment of planar polarity GO:0090175 2 0.010
muscle contraction GO:0006936 88 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
tube development GO:0035295 89 0.010
secretion GO:0046903 307 0.010
response to hyperoxia GO:0055093 45 0.010
cation homeostasis GO:0055080 195 0.010
regulation of ion transport GO:0043269 245 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.010
taxis GO:0042330 67 0.010
synaptic vesicle endocytosis GO:0048488 4 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
gamete generation GO:0007276 124 0.010

Tbc1d2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011