Rattus norvegicus

35 known processes

Pax2

paired box 2

Pax2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.057
Fly
regulation of neurogenesis GO:0050767 247 0.051
Fly
regulation of multicellular organismal development GO:2000026 376 0.045
Fly
cellular component assembly GO:0022607 360 0.044
cellular component biogenesis GO:0044085 368 0.043
regulation of cellular component organization GO:0051128 368 0.042
regulation of cell differentiation GO:0045595 320 0.041
Fly
chemical homeostasis GO:0048878 292 0.041
neuron projection development GO:0031175 273 0.040
Fly
positive regulation of multicellular organismal process GO:0051240 387 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
Human
cellular response to oxygen containing compound GO:1901701 386 0.039
cell projection organization GO:0030030 302 0.038
Fly
regulation of nervous system development GO:0051960 264 0.037
Fly
neuron development GO:0048666 286 0.036
Fly
anatomical structure morphogenesis GO:0009653 298 0.035
Human Fly
homeostatic process GO:0042592 331 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
regulation of cell development GO:0060284 263 0.035
Fly
protein phosphorylation GO:0006468 345 0.034
response to extracellular stimulus GO:0009991 380 0.033
cellular homeostasis GO:0019725 252 0.033
oxoacid metabolic process GO:0043436 290 0.033
protein complex biogenesis GO:0070271 263 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
macromolecular complex assembly GO:0065003 273 0.032
organic acid metabolic process GO:0006082 292 0.032
cellular chemical homeostasis GO:0055082 247 0.032
single organism biosynthetic process GO:0044711 342 0.032
reproductive process GO:0022414 372 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
Human
regulation of neuron differentiation GO:0045664 208 0.032
Fly
response to inorganic substance GO:0010035 377 0.032
cation transport GO:0006812 382 0.032
regulation of rna biosynthetic process GO:2001141 381 0.031
Human Rat Fly
protein complex subunit organization GO:0071822 302 0.031
negative regulation of metabolic process GO:0009892 331 0.031
Human
regulation of protein metabolic process GO:0051246 289 0.031
Human
response to peptide GO:1901652 292 0.031
regulation of transcription dna templated GO:0006355 374 0.031
Human Rat Fly
protein complex assembly GO:0006461 263 0.030
regulation of cellular localization GO:0060341 263 0.030
amine metabolic process GO:0009308 38 0.030
cellular response to stress GO:0033554 269 0.030
regulation of programmed cell death GO:0043067 341 0.029
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
Human Rat Fly
positive regulation of developmental process GO:0051094 283 0.029
response to peptide hormone GO:0043434 278 0.028
rna metabolic process GO:0016070 406 0.028
Human Rat Fly
negative regulation of cellular metabolic process GO:0031324 281 0.028
Human
regulation of signal transduction GO:0009966 318 0.028
ion transmembrane transport GO:0034220 365 0.028
cation transmembrane transport GO:0098655 263 0.028
cellular amine metabolic process GO:0044106 38 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
Human Rat Fly
positive regulation of biosynthetic process GO:0009891 319 0.027
Human Rat Fly
ion homeostasis GO:0050801 212 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
metal ion transport GO:0030001 289 0.026
regulation of cell proliferation GO:0042127 359 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
transmembrane transport GO:0055085 412 0.026
intracellular signal transduction GO:0035556 314 0.026
programmed cell death GO:0012501 392 0.026
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
Human Rat Fly
apoptotic process GO:0006915 381 0.026
Human
response to nutrient levels GO:0031667 370 0.026
secretion GO:0046903 307 0.026
organelle organization GO:0006996 266 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
reproduction GO:0000003 245 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
cell cell signaling GO:0007267 335 0.025
regulation of rna metabolic process GO:0051252 391 0.025
Human Rat Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
Human Rat Fly
multicellular organism reproduction GO:0032504 233 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
rna biosynthetic process GO:0032774 380 0.025
Human Rat Fly
cellular response to organic cyclic compound GO:0071407 202 0.025
positive regulation of response to stimulus GO:0048584 285 0.024
response to carbohydrate GO:0009743 183 0.024
nucleic acid templated transcription GO:0097659 379 0.024
Human Rat Fly
positive regulation of transport GO:0051050 245 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
secretion by cell GO:0032940 248 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
Human Rat Fly
cellular catabolic process GO:0044248 295 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
regulation of apoptotic process GO:0042981 335 0.024
Human
regulation of cellular amine metabolic process GO:0033238 8 0.024
catabolic process GO:0009056 351 0.024
single organism reproductive process GO:0044702 297 0.024
cellular divalent inorganic cation homeostasis GO:0072503 162 0.024
central nervous system development GO:0007417 311 0.024
regulation of secretion GO:0051046 224 0.023
metal ion homeostasis GO:0055065 186 0.023
regulation of cell projection organization GO:0031344 175 0.023
cellular ketone metabolic process GO:0042180 51 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
Human Rat Fly
cellular response to hormone stimulus GO:0032870 247 0.023
circulatory system process GO:0003013 183 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
positive regulation of nervous system development GO:0051962 178 0.023
nucleotide metabolic process GO:0009117 279 0.023
nitrogen compound transport GO:0071705 229 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
regulation of molecular function GO:0065009 398 0.022
Human
macromolecule localization GO:0033036 252 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
Human Rat Fly
response to external biotic stimulus GO:0043207 221 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
regulation of protein modification process GO:0031399 194 0.022
transcription dna templated GO:0006351 377 0.022
Human Rat Fly
cellular component movement GO:0006928 248 0.022
blood circulation GO:0008015 183 0.022
cellular cation homeostasis GO:0030003 180 0.022
protein oligomerization GO:0051259 191 0.021
positive regulation of cell communication GO:0010647 271 0.021
calcium ion homeostasis GO:0055074 162 0.021
neurological system process GO:0050877 219 0.021
regulation of catalytic activity GO:0050790 304 0.021
Human
cellular response to growth factor stimulus GO:0071363 162 0.021
signal release GO:0023061 145 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
negative regulation of cell communication GO:0010648 158 0.021
cation homeostasis GO:0055080 195 0.021
regulation of secretion by cell GO:1903530 208 0.021
positive regulation of molecular function GO:0044093 230 0.021
lipid metabolic process GO:0006629 283 0.021
organophosphate metabolic process GO:0019637 370 0.021
regulation of hormone levels GO:0010817 187 0.021
multicellular organismal reproductive process GO:0048609 233 0.020
response to growth factor GO:0070848 189 0.020
response to cytokine GO:0034097 215 0.020
response to metal ion GO:0010038 253 0.020
response to corticosteroid GO:0031960 235 0.020
response to glucocorticoid GO:0051384 223 0.020
single organism catabolic process GO:0044712 283 0.020
regulation of neuron projection development GO:0010975 161 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of gene expression GO:0010628 244 0.020
Human Rat Fly
regulation of ion transport GO:0043269 245 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
response to nutrient GO:0007584 248 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
Human Rat Fly
protein localization GO:0008104 191 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
Human Rat Fly
response to estrogen GO:0043627 232 0.019
cellular response to lipid GO:0071396 201 0.019
response to decreased oxygen levels GO:0036293 237 0.019
neuron projection morphogenesis GO:0048812 122 0.019
Fly
positive regulation of cell development GO:0010720 176 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
negative regulation of gene expression GO:0010629 199 0.019
Human
regulation of system process GO:0044057 208 0.019
cell projection morphogenesis GO:0048858 123 0.019
Fly
locomotion GO:0040011 237 0.019
head development GO:0060322 247 0.019
multi organism reproductive process GO:0044703 262 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
Human
single organism intracellular transport GO:1902582 166 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
regulation of phosphorylation GO:0042325 248 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.018
synaptic transmission GO:0007268 235 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
response to oxygen levels GO:0070482 265 0.018
regulation of membrane potential GO:0042391 110 0.018
negative regulation of signaling GO:0023057 157 0.018
single organism organelle organization GO:1902589 180 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
defense response GO:0006952 194 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of rna metabolic process GO:0051254 203 0.017
Human Rat Fly
response to monosaccharide GO:0034284 159 0.017
cell part morphogenesis GO:0032990 123 0.017
Fly
brain development GO:0007420 247 0.017
localization of cell GO:0051674 202 0.017
anterior posterior pattern specification GO:0009952 1 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
response to hypoxia GO:0001666 231 0.017
proteolysis GO:0006508 175 0.017
Human
purine containing compound metabolic process GO:0072521 253 0.017
cellular ion homeostasis GO:0006873 184 0.017
negative regulation of cell death GO:0060548 229 0.017
Human
intracellular transport GO:0046907 185 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of anatomical structure size GO:0090066 135 0.017
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
positive regulation of signaling GO:0023056 270 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
Human
negative regulation of apoptotic process GO:0043066 181 0.017
Human
response to hexose GO:0009746 144 0.016
response to other organism GO:0051707 220 0.016
response to ketone GO:1901654 182 0.016
immune system process GO:0002376 204 0.016
response to bacterium GO:0009617 200 0.016
regeneration GO:0031099 163 0.016
positive regulation of protein modification process GO:0031401 142 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
cellular component morphogenesis GO:0032989 155 0.016
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
response to acid chemical GO:0001101 222 0.016
amide transport GO:0042886 105 0.016
cytoskeleton organization GO:0007010 111 0.016
positive regulation of protein metabolic process GO:0051247 178 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
Human
aging GO:0007568 241 0.015
negative regulation of transport GO:0051051 136 0.015
organic substance catabolic process GO:1901575 316 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Human
protein transport GO:0015031 132 0.015
response to biotic stimulus GO:0009607 226 0.015
coenzyme metabolic process GO:0006732 86 0.015
regulation of hormone secretion GO:0046883 106 0.015
divalent metal ion transport GO:0070838 132 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
Human
positive regulation of secretion by cell GO:1903532 128 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
Human
positive regulation of secretion GO:0051047 140 0.015
positive regulation of cell death GO:0010942 184 0.015
calcium ion transport GO:0006816 131 0.015
response to alkaloid GO:0043279 132 0.015
establishment of protein localization GO:0045184 141 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
Fly
response to lipopolysaccharide GO:0032496 191 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
ras protein signal transduction GO:0007265 29 0.015
muscle system process GO:0003012 115 0.015
small molecule biosynthetic process GO:0044283 124 0.014
gamete generation GO:0007276 124 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
axis specification GO:0009798 4 0.014
axon development GO:0061564 96 0.014
cellular lipid metabolic process GO:0044255 208 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
Human Rat Fly
positive regulation of neuron differentiation GO:0045666 126 0.014
chromosome segregation GO:0007059 2 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
hormone secretion GO:0046879 115 0.014
positive regulation of ion transport GO:0043270 94 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
Fly
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
Human Rat Fly
hormone transport GO:0009914 121 0.014
regulation of body fluid levels GO:0050878 90 0.014
peptide secretion GO:0002790 86 0.014
cell motility GO:0048870 202 0.014
developmental process involved in reproduction GO:0003006 159 0.014
epithelium development GO:0060429 96 0.013
Human
anion transport GO:0006820 178 0.013
sexual reproduction GO:0019953 148 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
sensory perception GO:0007600 101 0.013
cellular macromolecule localization GO:0070727 122 0.013
divalent inorganic cation transport GO:0072511 134 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of peptide transport GO:0090087 87 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
gastrulation GO:0007369 2 0.013
response to oxidative stress GO:0006979 186 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
regulation of peptide secretion GO:0002791 82 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
cellular protein localization GO:0034613 122 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
response to vitamin GO:0033273 131 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
Human
regulation of catabolic process GO:0009894 113 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
Fly
response to wounding GO:0009611 254 0.013
response to estradiol GO:0032355 164 0.012
regulation of transmembrane transport GO:0034762 122 0.012
cell morphogenesis GO:0000902 142 0.012
Fly
gland development GO:0048732 155 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
response to radiation GO:0009314 137 0.012
regulation of response to stress GO:0080134 126 0.012
regulation of blood pressure GO:0008217 83 0.012
cell migration GO:0016477 197 0.012
peptide hormone secretion GO:0030072 84 0.012
growth GO:0040007 165 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
regulation of locomotion GO:0040012 148 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
rhythmic process GO:0048511 156 0.012
peptide transport GO:0015833 97 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
cellular response to alcohol GO:0097306 87 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of metal ion transport GO:0010959 118 0.012
positive regulation of signal transduction GO:0009967 175 0.012
negative regulation of innate immune response GO:0045824 4 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of organelle organization GO:0033043 80 0.012
oxidation reduction process GO:0055114 304 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
developmental growth GO:0048589 100 0.012
nucleoside metabolic process GO:0009116 179 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of synaptic transmission GO:0050804 141 0.012
response to toxic substance GO:0009636 133 0.012
regulation of cellular component movement GO:0051270 150 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
Human
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
Human
regulation of tube size GO:0035150 89 0.012
carbohydrate homeostasis GO:0033500 75 0.012
embryonic pattern specification GO:0009880 1 0.012
tissue development GO:0009888 252 0.012
Human Fly
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
negative regulation of developmental process GO:0051093 125 0.011
peptidyl amino acid modification GO:0018193 126 0.011
cellular response to external stimulus GO:0071496 118 0.011
single organism cellular localization GO:1902580 102 0.011
carboxylic acid transport GO:0046942 115 0.011
response to ethanol GO:0045471 162 0.011
negative regulation of signal transduction GO:0009968 83 0.011
response to reactive oxygen species GO:0000302 120 0.011
sequestering of calcium ion GO:0051208 8 0.011
wound healing GO:0042060 122 0.011
regulation of response to external stimulus GO:0032101 106 0.011
vascular process in circulatory system GO:0003018 96 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
spermatogenesis GO:0007283 99 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
cellular response to peptide GO:1901653 133 0.011
behavior GO:0007610 205 0.011
organic acid transport GO:0015849 116 0.011
heart morphogenesis GO:0003007 3 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of blood vessel size GO:0050880 89 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
reproductive system development GO:0061458 128 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
regulation of blood circulation GO:1903522 110 0.011
lipid biosynthetic process GO:0008610 128 0.011
male gamete generation GO:0048232 99 0.011
muscle contraction GO:0006936 88 0.011
reproductive structure development GO:0048608 128 0.011
regulation of hydrolase activity GO:0051336 143 0.011
Human
regulation of cellular catabolic process GO:0031329 101 0.011
sequestering of metal ion GO:0051238 9 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
Human
maintenance of location GO:0051235 17 0.011
cell adhesion GO:0007155 110 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
positive regulation of cell migration GO:0030335 96 0.011
eye morphogenesis GO:0048592 4 0.011
Fly
potassium ion transport GO:0006813 97 0.011
regulation of protein kinase activity GO:0045859 105 0.011
regulation of growth GO:0040008 105 0.011
cofactor metabolic process GO:0051186 95 0.011
cellular response to acid chemical GO:0071229 75 0.011
cell cycle GO:0007049 101 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of nervous system development GO:0051961 79 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
response to insulin GO:0032868 133 0.011
transmission of nerve impulse GO:0019226 42 0.011
negative regulation of secretion GO:0051048 82 0.010
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.010
salivary gland development GO:0007431 3 0.010
chemosensory behavior GO:0007635 2 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
regulation of kinase activity GO:0043549 117 0.010
positive regulation of locomotion GO:0040017 102 0.010
actin filament based process GO:0030029 86 0.010
hepaticobiliary system development GO:0061008 90 0.010
negative regulation of cell development GO:0010721 82 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
regulation of cell migration GO:0030334 128 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
Human
biological adhesion GO:0022610 110 0.010
organic acid biosynthetic process GO:0016053 83 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
sex differentiation GO:0007548 113 0.010
cell growth GO:0016049 104 0.010
negative regulation of molecular function GO:0044092 133 0.010
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
tube development GO:0035295 89 0.010
Human
rna localization GO:0006403 4 0.010
lipid storage GO:0019915 1 0.010
neuronal action potential GO:0019228 35 0.010
regulation of calcium ion transport GO:0051924 77 0.010
single organism behavior GO:0044708 130 0.010
carbohydrate metabolic process GO:0005975 130 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
mapk cascade GO:0000165 140 0.010

Pax2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
Human
nervous system disease DOID:863 0 0.041
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.012