Rattus norvegicus

0 known processes

Wrap53

WD repeat containing, antisense to TP53

(Aliases: Wdr79,MGC94565)

Wrap53 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.095
cellular response to stress GO:0033554 269 0.085
positive regulation of phosphate metabolic process GO:0045937 262 0.077
catabolic process GO:0009056 351 0.068
single organism catabolic process GO:0044712 283 0.065
neuron differentiation GO:0030182 368 0.064
organic acid metabolic process GO:0006082 292 0.063
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.062
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
Human
cell projection organization GO:0030030 302 0.055
regulation of molecular function GO:0065009 398 0.055
Human
oxoacid metabolic process GO:0043436 290 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
regulation of multicellular organismal development GO:2000026 376 0.053
regulation of rna biosynthetic process GO:2001141 381 0.053
cellular catabolic process GO:0044248 295 0.052
apoptotic process GO:0006915 381 0.052
organelle organization GO:0006996 266 0.051
Human Fly
regulation of protein modification process GO:0031399 194 0.051
response to nutrient levels GO:0031667 370 0.048
carbohydrate derivative catabolic process GO:1901136 147 0.048
regulation of protein metabolic process GO:0051246 289 0.047
intracellular signal transduction GO:0035556 314 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.045
cellular component assembly GO:0022607 360 0.044
Human
regulation of rna metabolic process GO:0051252 391 0.044
regulation of signal transduction GO:0009966 318 0.044
response to extracellular stimulus GO:0009991 380 0.044
negative regulation of metabolic process GO:0009892 331 0.043
rna biosynthetic process GO:0032774 380 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
regulation of protein phosphorylation GO:0001932 183 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
protein phosphorylation GO:0006468 345 0.042
transcription dna templated GO:0006351 377 0.042
cellular response to endogenous stimulus GO:0071495 377 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.041
positive regulation of biosynthetic process GO:0009891 319 0.040
Human
macromolecule localization GO:0033036 252 0.040
cellular component biogenesis GO:0044085 368 0.040
Human
regulation of transcription dna templated GO:0006355 374 0.040
response to inorganic substance GO:0010035 377 0.039
regulation of cell proliferation GO:0042127 359 0.039
cellular amino acid metabolic process GO:0006520 107 0.039
response to hexose GO:0009746 144 0.038
cellular response to oxygen containing compound GO:1901701 386 0.038
organophosphate metabolic process GO:0019637 370 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.037
rna metabolic process GO:0016070 406 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.036
response to nutrient GO:0007584 248 0.036
protein complex assembly GO:0006461 263 0.035
organonitrogen compound catabolic process GO:1901565 179 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
cell cell signaling GO:0007267 335 0.034
nucleoside phosphate metabolic process GO:0006753 283 0.034
regulation of cellular component organization GO:0051128 368 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
reproductive process GO:0022414 372 0.033
gastrulation GO:0007369 2 0.033
heterocycle catabolic process GO:0046700 167 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.033
organic cyclic compound catabolic process GO:1901361 175 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
cellular amine metabolic process GO:0044106 38 0.033
macromolecular complex subunit organization GO:0043933 339 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
growth GO:0040007 165 0.032
protein complex biogenesis GO:0070271 263 0.032
amine metabolic process GO:0009308 38 0.032
regulation of programmed cell death GO:0043067 341 0.031
regulation of apoptotic process GO:0042981 335 0.031
purine nucleoside metabolic process GO:0042278 169 0.031
regulation of catalytic activity GO:0050790 304 0.031
Human
regulation of cellular amine metabolic process GO:0033238 8 0.031
ribonucleoside metabolic process GO:0009119 174 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
ribonucleoside catabolic process GO:0042454 126 0.031
regulation of cell projection organization GO:0031344 175 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
response to oxidative stress GO:0006979 186 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
protein localization GO:0008104 191 0.030
nucleoside triphosphate metabolic process GO:0009141 144 0.029
response to peptide GO:1901652 292 0.029
double strand break repair GO:0006302 1 0.029
regulation of nervous system development GO:0051960 264 0.029
positive regulation of molecular function GO:0044093 230 0.028
Human
positive regulation of cell death GO:0010942 184 0.028
response to cytokine GO:0034097 215 0.028
organophosphate catabolic process GO:0046434 148 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
response to monosaccharide GO:0034284 159 0.028
tissue development GO:0009888 252 0.028
regulation of phosphorylation GO:0042325 248 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
neuron projection development GO:0031175 273 0.027
aromatic compound catabolic process GO:0019439 168 0.027
protein complex subunit organization GO:0071822 302 0.027
aging GO:0007568 241 0.027
neuron development GO:0048666 286 0.026
response to carbohydrate GO:0009743 183 0.026
nucleobase containing compound catabolic process GO:0034655 152 0.026
reproduction GO:0000003 245 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
Human
cellular ketone metabolic process GO:0042180 51 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
negative regulation of gene expression GO:0010629 199 0.025
homeostatic process GO:0042592 331 0.025
synaptic transmission GO:0007268 235 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
regulation of kinase activity GO:0043549 117 0.025
programmed cell death GO:0012501 392 0.025
cellular protein localization GO:0034613 122 0.025
positive regulation of gene expression GO:0010628 244 0.025
ribonucleotide catabolic process GO:0009261 136 0.024
positive regulation of protein modification process GO:0031401 142 0.024
multi organism reproductive process GO:0044703 262 0.024
response to peptide hormone GO:0043434 278 0.024
protein transport GO:0015031 132 0.024
nucleoside metabolic process GO:0009116 179 0.024
small molecule biosynthetic process GO:0044283 124 0.024
cellular macromolecule localization GO:0070727 122 0.024
proteolysis GO:0006508 175 0.024
establishment of protein localization GO:0045184 141 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
response to hypoxia GO:0001666 231 0.023
purine ribonucleotide catabolic process GO:0009154 136 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
positive regulation of cell communication GO:0010647 271 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
response to oxygen levels GO:0070482 265 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
protein oligomerization GO:0051259 191 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
response to glucose GO:0009749 136 0.022
macromolecular complex assembly GO:0065003 273 0.022
single organism reproductive process GO:0044702 297 0.022
nucleic acid templated transcription GO:0097659 379 0.022
nucleoside catabolic process GO:0009164 126 0.022
response to organophosphorus GO:0046683 102 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
regulation of neurogenesis GO:0050767 247 0.022
cellular response to cytokine stimulus GO:0071345 127 0.021
intracellular transport GO:0046907 185 0.021
response to decreased oxygen levels GO:0036293 237 0.021
regulation of cell differentiation GO:0045595 320 0.021
cellular lipid metabolic process GO:0044255 208 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.020
mapk cascade GO:0000165 140 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
lipid biosynthetic process GO:0008610 128 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
single organism organelle organization GO:1902589 180 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
cellular component movement GO:0006928 248 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
central nervous system development GO:0007417 311 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of cell communication GO:0010648 158 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
response to estrogen GO:0043627 232 0.018
purine containing compound metabolic process GO:0072521 253 0.018
dna metabolic process GO:0006259 96 0.018
Human
regulation of cellular localization GO:0060341 263 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
eye morphogenesis GO:0048592 4 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
single organism intracellular transport GO:1902582 166 0.018
regulation of intracellular signal transduction GO:1902531 218 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
response to glucocorticoid GO:0051384 223 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
negative regulation of cell death GO:0060548 229 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
regulation of secretion by cell GO:1903530 208 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
transmembrane transport GO:0055085 412 0.017
single organism biosynthetic process GO:0044711 342 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
regulation of neuron differentiation GO:0045664 208 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.017
cellular response to peptide GO:1901653 133 0.017
positive regulation of cell development GO:0010720 176 0.017
response to wounding GO:0009611 254 0.017
purine containing compound catabolic process GO:0072523 138 0.017
heart morphogenesis GO:0003007 3 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
peptidyl amino acid modification GO:0018193 126 0.017
chemical homeostasis GO:0048878 292 0.016
cation transport GO:0006812 382 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
regulation of transferase activity GO:0051338 123 0.016
Human
negative regulation of transcription dna templated GO:0045892 116 0.016
response to purine containing compound GO:0014074 126 0.016
response to acid chemical GO:0001101 222 0.016
nitrogen compound transport GO:0071705 229 0.016
regulation of mapk cascade GO:0043408 116 0.016
brain development GO:0007420 247 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
secretion GO:0046903 307 0.016
cell cycle GO:0007049 101 0.016
vesicle mediated transport GO:0016192 181 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
regulation of hydrolase activity GO:0051336 143 0.015
axis specification GO:0009798 4 0.015
response to external biotic stimulus GO:0043207 221 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
organic acid biosynthetic process GO:0016053 83 0.015
cardiovascular system development GO:0072358 134 0.015
response to biotic stimulus GO:0009607 226 0.015
nucleotide catabolic process GO:0009166 139 0.015
lipid metabolic process GO:0006629 283 0.015
regulation of anatomical structure size GO:0090066 135 0.015
developmental growth GO:0048589 100 0.015
negative regulation of signaling GO:0023057 157 0.015
adult locomotory behavior GO:0008344 4 0.014
vasculature development GO:0001944 70 0.014
regulation of system process GO:0044057 208 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.014
synaptic vesicle endocytosis GO:0048488 4 0.014
response to vitamin GO:0033273 131 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
multicellular organism growth GO:0035264 1 0.014
developmental process involved in reproduction GO:0003006 159 0.014
immune system process GO:0002376 204 0.014
response to temperature stimulus GO:0009266 94 0.014
regulation of cell growth GO:0001558 85 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
circulatory system development GO:0072359 134 0.014
positive regulation of signaling GO:0023056 270 0.014
positive regulation of apoptotic process GO:0043065 154 0.013
response to metal ion GO:0010038 253 0.013
cellular component morphogenesis GO:0032989 155 0.013
immune response GO:0006955 104 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
regulation of cell development GO:0060284 263 0.013
positive regulation of nervous system development GO:0051962 178 0.013
cellular chemical homeostasis GO:0055082 247 0.013
positive regulation of transport GO:0051050 245 0.013
positive regulation of developmental process GO:0051094 283 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
regulation of catabolic process GO:0009894 113 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
multi multicellular organism process GO:0044706 138 0.013
response to reactive oxygen species GO:0000302 120 0.013
response to lipopolysaccharide GO:0032496 191 0.013
negative regulation of molecular function GO:0044092 133 0.013
tube formation GO:0035148 3 0.013
intracellular protein transport GO:0006886 79 0.013
response to estradiol GO:0032355 164 0.013
response to corticosteroid GO:0031960 235 0.013
actin filament based process GO:0030029 86 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
response to radiation GO:0009314 137 0.012
carbohydrate homeostasis GO:0033500 75 0.012
female pregnancy GO:0007565 122 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.012
fatty acid metabolic process GO:0006631 99 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
negative regulation of developmental process GO:0051093 125 0.012
epithelial cell proliferation GO:0050673 54 0.012
sexual reproduction GO:0019953 148 0.012
anterior posterior pattern specification GO:0009952 1 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
Human
cellular response to growth factor stimulus GO:0071363 162 0.012
response to bacterium GO:0009617 200 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
localization of cell GO:0051674 202 0.012
jak stat cascade GO:0007259 26 0.012
protein maturation GO:0051604 68 0.012
microtubule organizing center organization GO:0031023 1 0.012
positive regulation of kinase activity GO:0033674 77 0.012
regulation of growth GO:0040008 105 0.012
signal release GO:0023061 145 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.011
regulation of membrane potential GO:0042391 110 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
head development GO:0060322 247 0.011
cellular homeostasis GO:0019725 252 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of protein kinase activity GO:0045859 105 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
secretion by cell GO:0032940 248 0.011
dephosphorylation GO:0016311 98 0.011
tube development GO:0035295 89 0.011
mesoderm development GO:0007498 2 0.011
cytoplasmic transport GO:0016482 115 0.011
formation of primary germ layer GO:0001704 1 0.011
multicellular organism reproduction GO:0032504 233 0.011
protein homooligomerization GO:0051260 91 0.011
cell growth GO:0016049 104 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
inflammatory response GO:0006954 150 0.011
protein targeting GO:0006605 61 0.011
cellular response to lipid GO:0071396 201 0.011
centrosome organization GO:0051297 1 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cell morphogenesis GO:0000902 142 0.011
embryonic pattern specification GO:0009880 1 0.011
nucleotide metabolic process GO:0009117 279 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of secretion GO:0051046 224 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
response to ethanol GO:0045471 162 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of neuron projection development GO:0010975 161 0.010
blood vessel morphogenesis GO:0048514 58 0.010
locomotion GO:0040011 237 0.010
positive regulation of signal transduction GO:0009967 175 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
cellular response to tumor necrosis factor GO:0071356 46 0.010
neurotransmitter uptake GO:0001504 3 0.010
single organism membrane organization GO:0044802 74 0.010
cofactor metabolic process GO:0051186 95 0.010
response to other organism GO:0051707 220 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
negative regulation of transport GO:0051051 136 0.010
ion homeostasis GO:0050801 212 0.010
spindle organization GO:0007051 2 0.010
negative regulation of response to stimulus GO:0048585 155 0.010

Wrap53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of cellular proliferation DOID:14566 0 0.013
musculoskeletal system disease DOID:17 0 0.012
central nervous system disease DOID:331 0 0.011