Rattus norvegicus

0 known processes

Krt12

keratin 12

(Aliases: Krt1-12,Ka12)

Krt12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular cation homeostasis GO:0030003 180 0.261
programmed cell death GO:0012501 392 0.172
cellular divalent inorganic cation homeostasis GO:0072503 162 0.144
cellular calcium ion homeostasis GO:0006874 160 0.139
homeostatic process GO:0042592 331 0.129
transmembrane transport GO:0055085 412 0.128
divalent inorganic cation homeostasis GO:0072507 165 0.122
response to inorganic substance GO:0010035 377 0.121
Rat
metal ion transport GO:0030001 289 0.116
cellular metal ion homeostasis GO:0006875 172 0.090
cellular response to lipid GO:0071396 201 0.088
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.087
positive regulation of response to stimulus GO:0048584 285 0.087
regulation of multicellular organismal development GO:2000026 376 0.085
positive regulation of multicellular organismal process GO:0051240 387 0.081
ion homeostasis GO:0050801 212 0.078
response to nutrient levels GO:0031667 370 0.076
cytosolic calcium ion homeostasis GO:0051480 140 0.075
circulatory system process GO:0003013 183 0.074
g protein coupled receptor signaling pathway GO:0007186 242 0.072
tissue development GO:0009888 252 0.068
Mouse Rat
positive regulation of cellular component organization GO:0051130 200 0.065
positive regulation of developmental process GO:0051094 283 0.063
inflammatory response GO:0006954 150 0.063
immune system process GO:0002376 204 0.061
protein phosphorylation GO:0006468 345 0.060
cation transport GO:0006812 382 0.059
metal ion homeostasis GO:0055065 186 0.058
organelle organization GO:0006996 266 0.054
apoptotic process GO:0006915 381 0.054
response to hypoxia GO:0001666 231 0.053
reproductive process GO:0022414 372 0.053
Rat
oxoacid metabolic process GO:0043436 290 0.051
cation homeostasis GO:0055080 195 0.051
cellular ion homeostasis GO:0006873 184 0.050
regulation of protein phosphorylation GO:0001932 183 0.048
anatomical structure morphogenesis GO:0009653 298 0.048
Rat
carboxylic acid metabolic process GO:0019752 289 0.048
cellular chemical homeostasis GO:0055082 247 0.048
nucleic acid templated transcription GO:0097659 379 0.048
negative regulation of programmed cell death GO:0043069 183 0.048
sodium ion transport GO:0006814 82 0.048
sodium ion transmembrane transport GO:0035725 67 0.047
positive regulation of cell communication GO:0010647 271 0.047
macromolecule localization GO:0033036 252 0.047
monovalent inorganic cation transport GO:0015672 172 0.046
potassium ion transport GO:0006813 97 0.046
head development GO:0060322 247 0.046
secretion by cell GO:0032940 248 0.045
signal transduction by phosphorylation GO:0023014 144 0.045
signal release GO:0023061 145 0.045
divalent inorganic cation transport GO:0072511 134 0.045
response to decreased oxygen levels GO:0036293 237 0.044
defense response GO:0006952 194 0.044
inorganic ion transmembrane transport GO:0098660 229 0.044
response to biotic stimulus GO:0009607 226 0.044
macromolecular complex subunit organization GO:0043933 339 0.042
growth GO:0040007 165 0.042
cellular component movement GO:0006928 248 0.042
positive regulation of mapk cascade GO:0043410 92 0.042
regulation of apoptotic process GO:0042981 335 0.040
response to oxygen levels GO:0070482 265 0.039
response to external biotic stimulus GO:0043207 221 0.039
reproductive system development GO:0061458 128 0.039
regulation of membrane potential GO:0042391 110 0.038
regulation of response to external stimulus GO:0032101 106 0.038
cation transmembrane transport GO:0098655 263 0.038
sensory perception of pain GO:0019233 73 0.038
wound healing GO:0042060 122 0.038
response to extracellular stimulus GO:0009991 380 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
regulation of protein metabolic process GO:0051246 289 0.037
cellular homeostasis GO:0019725 252 0.037
cellular response to hormone stimulus GO:0032870 247 0.037
response to molecule of bacterial origin GO:0002237 194 0.037
negative regulation of cell death GO:0060548 229 0.036
chemical homeostasis GO:0048878 292 0.036
calcium ion homeostasis GO:0055074 162 0.036
neuron death GO:0070997 127 0.035
intracellular signal transduction GO:0035556 314 0.035
male sex differentiation GO:0046661 64 0.034
response to metal ion GO:0010038 253 0.034
Rat
localization of cell GO:0051674 202 0.034
positive regulation of secretion by cell GO:1903532 128 0.034
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
regulation of anatomical structure size GO:0090066 135 0.034
regulation of behavior GO:0050795 61 0.034
regulation of programmed cell death GO:0043067 341 0.034
secretion GO:0046903 307 0.034
regulation of cellular component organization GO:0051128 368 0.033
regulation of transcription dna templated GO:0006355 374 0.033
cell migration GO:0016477 197 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.032
positive regulation of signaling GO:0023056 270 0.032
regulation of metal ion transport GO:0010959 118 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
rna biosynthetic process GO:0032774 380 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
biological adhesion GO:0022610 110 0.032
response to transition metal nanoparticle GO:1990267 122 0.031
Rat
positive regulation of secretion GO:0051047 140 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
regulation of protein modification process GO:0031399 194 0.031
transcription dna templated GO:0006351 377 0.031
positive regulation of immune system process GO:0002684 90 0.031
reproductive structure development GO:0048608 128 0.030
response to growth factor GO:0070848 189 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
regulation of growth GO:0040008 105 0.030
multi organism reproductive process GO:0044703 262 0.030
Rat
regulation of cell migration GO:0030334 128 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
regulation of cell differentiation GO:0045595 320 0.029
protein oligomerization GO:0051259 191 0.029
response to bacterium GO:0009617 200 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
sexual reproduction GO:0019953 148 0.029
Rat
cell motility GO:0048870 202 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.028
hormone secretion GO:0046879 115 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
developmental growth GO:0048589 100 0.028
response to oxidative stress GO:0006979 186 0.027
cell matrix adhesion GO:0007160 19 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
response to estrogen GO:0043627 232 0.027
regulation of cellular localization GO:0060341 263 0.027
ion transmembrane transport GO:0034220 365 0.027
negative regulation of cell communication GO:0010648 158 0.027
regulation of homeostatic process GO:0032844 101 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.027
regeneration GO:0031099 163 0.026
protein complex biogenesis GO:0070271 263 0.026
brain development GO:0007420 247 0.026
amine metabolic process GO:0009308 38 0.026
organic acid metabolic process GO:0006082 292 0.025
neuron differentiation GO:0030182 368 0.025
cellular catabolic process GO:0044248 295 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
developmental process involved in reproduction GO:0003006 159 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
regulation of mapk cascade GO:0043408 116 0.024
single organism catabolic process GO:0044712 283 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
rna metabolic process GO:0016070 406 0.024
membrane organization GO:0061024 94 0.024
cellular component biogenesis GO:0044085 368 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
positive regulation of defense response GO:0031349 37 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
single organism reproductive process GO:0044702 297 0.024
Rat
protein heterooligomerization GO:0051291 89 0.023
protein complex subunit organization GO:0071822 302 0.023
regulation of protein kinase activity GO:0045859 105 0.023
regulation of cell motility GO:2000145 131 0.023
nucleoside metabolic process GO:0009116 179 0.023
positive regulation of molecular function GO:0044093 230 0.023
gonad development GO:0008406 104 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
gland development GO:0048732 155 0.022
regulation of system process GO:0044057 208 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
immune response GO:0006955 104 0.022
response to peptide GO:1901652 292 0.022
regulation of rna metabolic process GO:0051252 391 0.022
development of primary sexual characteristics GO:0045137 107 0.022
oxidation reduction process GO:0055114 304 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
regulation of cellular component movement GO:0051270 150 0.021
positive regulation of protein modification process GO:0031401 142 0.021
negative regulation of gene expression GO:0010629 199 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
Rat
positive regulation of synaptic transmission GO:0050806 62 0.021
cell cell signaling GO:0007267 335 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
sex differentiation GO:0007548 113 0.020
cellular amine metabolic process GO:0044106 38 0.020
heart contraction GO:0060047 57 0.020
regulation of catalytic activity GO:0050790 304 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
positive regulation of cell death GO:0010942 184 0.020
mapk cascade GO:0000165 140 0.020
positive regulation of cell migration GO:0030335 96 0.020
single organism intracellular transport GO:1902582 166 0.020
aging GO:0007568 241 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of locomotion GO:0040012 148 0.020
organophosphate metabolic process GO:0019637 370 0.020
response to vitamin GO:0033273 131 0.020
cellular response to molecule of bacterial origin GO:0071219 56 0.019
macromolecular complex assembly GO:0065003 273 0.019
multicellular organism reproduction GO:0032504 233 0.019
Rat
regulation of hydrolase activity GO:0051336 143 0.019
regulation of organelle organization GO:0033043 80 0.019
response to other organism GO:0051707 220 0.019
regulation of synaptic transmission GO:0050804 141 0.019
response to organophosphorus GO:0046683 102 0.019
rhythmic process GO:0048511 156 0.019
response to wounding GO:0009611 254 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
cardiovascular system development GO:0072358 134 0.019
cell adhesion GO:0007155 110 0.018
synaptic transmission GO:0007268 235 0.018
positive regulation of transport GO:0051050 245 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
regulation of transferase activity GO:0051338 123 0.018
sensory perception GO:0007600 101 0.018
vasculature development GO:0001944 70 0.018
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.018
single organism biosynthetic process GO:0044711 342 0.018
regulation of neuron death GO:1901214 115 0.018
regulation of molecular function GO:0065009 398 0.018
cellular response to mechanical stimulus GO:0071260 48 0.017
regulation of neurogenesis GO:0050767 247 0.017
multicellular organism growth GO:0035264 1 0.017
regulation of heart contraction GO:0008016 48 0.017
cell projection organization GO:0030030 302 0.017
cellular response to lipopolysaccharide GO:0071222 55 0.017
positive regulation of cell development GO:0010720 176 0.017
cell type specific apoptotic process GO:0097285 134 0.017
positive regulation of gene expression GO:0010628 244 0.017
regulation of hormone secretion GO:0046883 106 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
leukocyte migration GO:0050900 38 0.017
response to hydrogen peroxide GO:0042542 89 0.017
positive regulation of protein kinase activity GO:0045860 73 0.017
regulation of ion transport GO:0043269 245 0.017
nucleotide metabolic process GO:0009117 279 0.017
peptidyl amino acid modification GO:0018193 126 0.017
cellular amino acid metabolic process GO:0006520 107 0.016
response to mechanical stimulus GO:0009612 134 0.016
response to radiation GO:0009314 137 0.016
Rat
positive regulation of phosphorylation GO:0042327 177 0.016
single organism organelle organization GO:1902589 180 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
regulation of cell growth GO:0001558 85 0.016
female gonad development GO:0008585 53 0.016
response to nutrient GO:0007584 248 0.016
cell growth GO:0016049 104 0.016
cellular ketone metabolic process GO:0042180 51 0.016
cellular response to external stimulus GO:0071496 118 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
negative regulation of signal transduction GO:0009968 83 0.015
divalent metal ion transport GO:0070838 132 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
positive regulation of kinase activity GO:0033674 77 0.015
single organism membrane organization GO:0044802 74 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
urogenital system development GO:0001655 78 0.015
regulation of cell adhesion GO:0030155 52 0.015
calcium mediated signaling GO:0019722 23 0.015
cellular macromolecule localization GO:0070727 122 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of vasculature development GO:1901342 44 0.015
regulation of cell proliferation GO:0042127 359 0.015
muscle system process GO:0003012 115 0.015
cellular response to stress GO:0033554 269 0.014
central nervous system development GO:0007417 311 0.014
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.014
intracellular transport GO:0046907 185 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
action potential GO:0001508 54 0.014
lymphocyte migration GO:0072676 3 0.014
protein complex assembly GO:0006461 263 0.014
vascular process in circulatory system GO:0003018 96 0.014
purine containing compound metabolic process GO:0072521 253 0.014
catabolic process GO:0009056 351 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
glomerular mesangial cell proliferation GO:0072110 4 0.014
cellular component assembly GO:0022607 360 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
Rat
regulation of secretion by cell GO:1903530 208 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
regulation of map kinase activity GO:0043405 53 0.014
positive regulation of response to external stimulus GO:0032103 51 0.013
cell cycle GO:0007049 101 0.013
positive regulation of locomotion GO:0040017 102 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
cell substrate adhesion GO:0031589 29 0.013
regulation of secretion GO:0051046 224 0.013
regulation of response to stress GO:0080134 126 0.013
ovulation cycle process GO:0022602 50 0.013
regulation of phosphorylation GO:0042325 248 0.013
dephosphorylation GO:0016311 98 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of cytokine biosynthetic process GO:0042035 3 0.013
proteolysis GO:0006508 175 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of transferase activity GO:0051347 81 0.013
positive regulation of nervous system development GO:0051962 178 0.013
angioblast cell migration GO:0035476 1 0.013
response to ketone GO:1901654 182 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
blood circulation GO:0008015 183 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
gamete generation GO:0007276 124 0.012
Rat
fatty acid metabolic process GO:0006631 99 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
nitrogen compound transport GO:0071705 229 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
response to temperature stimulus GO:0009266 94 0.012
cardiac conduction GO:0061337 2 0.012
neuron projection development GO:0031175 273 0.012
response to heat GO:0009408 60 0.012
organic substance catabolic process GO:1901575 316 0.012
cytokine biosynthetic process GO:0042089 3 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
negative regulation of metabolic process GO:0009892 331 0.012
regulation of protein maturation GO:1903317 50 0.012
reproduction GO:0000003 245 0.012
Rat
response to monosaccharide GO:0034284 159 0.012
positive regulation of cell motility GO:2000147 97 0.012
cell cycle process GO:0022402 57 0.012
female sex differentiation GO:0046660 59 0.012
hormone transport GO:0009914 121 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.012
neuron development GO:0048666 286 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of protein processing GO:0010955 47 0.011
protein maturation GO:0051604 68 0.011
single organism cell adhesion GO:0098602 46 0.011
response to insulin GO:0032868 133 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
locomotion GO:0040011 237 0.011
neuronal action potential GO:0019228 35 0.011
response to reactive oxygen species GO:0000302 120 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
positive regulation of signal transduction GO:0009967 175 0.011
regulation of cell development GO:0060284 263 0.011
acid secretion GO:0046717 48 0.011
regulation of calcium ion transport GO:0051924 77 0.011
multicellular organismal signaling GO:0035637 44 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of protein processing GO:0070613 50 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of blood circulation GO:1903522 110 0.011
regulation of nervous system development GO:0051960 264 0.011
regulation of dna metabolic process GO:0051052 60 0.011
positive regulation of growth GO:0045927 55 0.011
negative regulation of protein maturation GO:1903318 47 0.011
ras protein signal transduction GO:0007265 29 0.011
positive regulation of map kinase activity GO:0043406 46 0.011
regulation of cytokine production GO:0001817 56 0.011
vesicle mediated transport GO:0016192 181 0.011
negative regulation of homeostatic process GO:0032845 47 0.011
regulation of cellular component biogenesis GO:0044087 86 0.010
negative regulation of response to external stimulus GO:0032102 37 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
response to cgmp GO:0070305 3 0.010
organ regeneration GO:0031100 101 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
establishment of protein localization GO:0045184 141 0.010
response to acid chemical GO:0001101 222 0.010
Rat
regulation of body fluid levels GO:0050878 90 0.010
cellular response to metal ion GO:0071248 55 0.010
positive regulation of catalytic activity GO:0043085 184 0.010

Krt12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.103
disease of anatomical entity DOID:7 0 0.103
nervous system disease DOID:863 0 0.103
eye and adnexa disease DOID:1492 0 0.074
eye disease DOID:5614 0 0.074
retinal disease DOID:5679 0 0.066
urinary system disease DOID:18 0 0.022
renal tubular transport disease DOID:447 0 0.012
kidney disease DOID:557 0 0.012