Rattus norvegicus

0 known processes

Krt18

keratin 18

(Aliases: Krt1-18,MGC109143)

Krt18 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.730
cellular response to tumor necrosis factor GO:0071356 46 0.539
cytokine mediated signaling pathway GO:0019221 43 0.423
wound healing GO:0042060 122 0.412
regeneration GO:0031099 163 0.385
response to inorganic substance GO:0010035 377 0.374
response to tumor necrosis factor GO:0034612 56 0.325
response to acid chemical GO:0001101 222 0.301
reproductive process GO:0022414 372 0.286
cell type specific apoptotic process GO:0097285 134 0.285
sarcomere organization GO:0045214 6 0.277
placenta development GO:0001890 22 0.266
reproductive structure development GO:0048608 128 0.264
cellular response to cytokine stimulus GO:0071345 127 0.260
single organism reproductive process GO:0044702 297 0.250
tissue regeneration GO:0042246 36 0.246
response to wounding GO:0009611 254 0.229
response to other organism GO:0051707 220 0.221
developmental growth GO:0048589 100 0.184
embryonic placenta development GO:0001892 1 0.180
programmed cell death GO:0012501 392 0.177
tissue development GO:0009888 252 0.169
response to cytokine GO:0034097 215 0.169
organelle assembly GO:0070925 22 0.165
single organism organelle organization GO:1902589 180 0.160
reproductive system development GO:0061458 128 0.149
cellular component assembly GO:0022607 360 0.148
apoptotic signaling pathway GO:0097190 27 0.146
response to external biotic stimulus GO:0043207 221 0.143
cellular component morphogenesis GO:0032989 155 0.140
muscle structure development GO:0061061 87 0.138
apoptotic process GO:0006915 381 0.134
cellular component biogenesis GO:0044085 368 0.132
neuron differentiation GO:0030182 368 0.122
anatomical structure formation involved in morphogenesis GO:0048646 83 0.120
anatomical structure morphogenesis GO:0009653 298 0.108
actin filament based process GO:0030029 86 0.107
regulation of cellular component organization GO:0051128 368 0.095
growth GO:0040007 165 0.084
cytoskeleton organization GO:0007010 111 0.080
response to glucocorticoid GO:0051384 223 0.077
response to corticosteroid GO:0031960 235 0.075
regulation of phosphate metabolic process GO:0019220 349 0.068
regulation of molecular function GO:0065009 398 0.067
response to monosaccharide GO:0034284 159 0.062
actin cytoskeleton organization GO:0030036 73 0.062
actomyosin structure organization GO:0031032 22 0.061
muscle cell differentiation GO:0042692 52 0.061
aging GO:0007568 241 0.060
response to extracellular stimulus GO:0009991 380 0.060
response to nutrient levels GO:0031667 370 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.057
cell morphogenesis GO:0000902 142 0.056
muscle cell development GO:0055001 26 0.055
positive regulation of response to stimulus GO:0048584 285 0.055
intracellular signal transduction GO:0035556 314 0.054
rna biosynthetic process GO:0032774 380 0.054
response to metal ion GO:0010038 253 0.052
cellular component assembly involved in morphogenesis GO:0010927 17 0.052
response to carbohydrate GO:0009743 183 0.052
embryo development GO:0009790 49 0.051
organic acid metabolic process GO:0006082 292 0.050
positive regulation of cell communication GO:0010647 271 0.048
regulation of transcription dna templated GO:0006355 374 0.048
response to hypoxia GO:0001666 231 0.047
macromolecule localization GO:0033036 252 0.047
nitrogen compound transport GO:0071705 229 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.043
protein phosphorylation GO:0006468 345 0.042
locomotion GO:0040011 237 0.041
chordate embryonic development GO:0043009 18 0.041
organelle organization GO:0006996 266 0.040
macromolecular complex subunit organization GO:0043933 339 0.038
ureteric bud development GO:0001657 14 0.037
positive regulation of protein metabolic process GO:0051247 178 0.037
regulation of multicellular organismal development GO:2000026 376 0.035
regulation of protein metabolic process GO:0051246 289 0.035
regulation of hydrolase activity GO:0051336 143 0.035
positive regulation of protein phosphorylation GO:0001934 135 0.035
cellular response to stress GO:0033554 269 0.034
cellular response to endogenous stimulus GO:0071495 377 0.034
neuron development GO:0048666 286 0.034
response to decreased oxygen levels GO:0036293 237 0.034
positive regulation of molecular function GO:0044093 230 0.033
regulation of protein phosphorylation GO:0001932 183 0.033
cellular amine metabolic process GO:0044106 38 0.033
cell motility GO:0048870 202 0.032
developmental process involved in reproduction GO:0003006 159 0.032
nucleic acid templated transcription GO:0097659 379 0.032
regulation of signal transduction GO:0009966 318 0.031
positive regulation of cellular amine metabolic process GO:0033240 3 0.031
cellular response to lipid GO:0071396 201 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
regulation of cell differentiation GO:0045595 320 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.031
regulation of cell proliferation GO:0042127 359 0.031
amine metabolic process GO:0009308 38 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
response to hexose GO:0009746 144 0.030
regulation of cellular localization GO:0060341 263 0.030
regulation of system process GO:0044057 208 0.030
transmembrane transport GO:0055085 412 0.030
response to oxygen levels GO:0070482 265 0.030
response to estrogen GO:0043627 232 0.030
carboxylic acid metabolic process GO:0019752 289 0.029
localization of cell GO:0051674 202 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
positive regulation of gene expression GO:0010628 244 0.028
macromolecular complex assembly GO:0065003 273 0.028
myofibril assembly GO:0030239 6 0.027
cellular amino acid metabolic process GO:0006520 107 0.026
response to ketone GO:1901654 182 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
positive regulation of developmental process GO:0051094 283 0.026
cellular ketone metabolic process GO:0042180 51 0.026
protein localization GO:0008104 191 0.026
secretion by cell GO:0032940 248 0.026
regulation of catalytic activity GO:0050790 304 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
response to toxic substance GO:0009636 133 0.025
response to oxidative stress GO:0006979 186 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
multicellular organism reproduction GO:0032504 233 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
regulation of phosphorylation GO:0042325 248 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
organic substance catabolic process GO:1901575 316 0.025
negative regulation of cell communication GO:0010648 158 0.025
regulation of nervous system development GO:0051960 264 0.024
regulation of peptide transport GO:0090087 87 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
cellular response to external stimulus GO:0071496 118 0.024
metal ion homeostasis GO:0055065 186 0.024
protein complex biogenesis GO:0070271 263 0.024
ion homeostasis GO:0050801 212 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
single organism intracellular transport GO:1902582 166 0.024
transcription dna templated GO:0006351 377 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
regulation of programmed cell death GO:0043067 341 0.024
positive regulation of transport GO:0051050 245 0.024
regulation of membrane potential GO:0042391 110 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
cellular chemical homeostasis GO:0055082 247 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
rna metabolic process GO:0016070 406 0.023
cell migration GO:0016477 197 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of response to stress GO:0080134 126 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
lipid metabolic process GO:0006629 283 0.023
regulation of hormone levels GO:0010817 187 0.023
peptidyl amino acid modification GO:0018193 126 0.023
secretion GO:0046903 307 0.023
cell cycle GO:0007049 101 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
neuron projection development GO:0031175 273 0.022
reproduction GO:0000003 245 0.022
regulation of cell development GO:0060284 263 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
female pregnancy GO:0007565 122 0.022
negative regulation of metabolic process GO:0009892 331 0.022
regulation of blood circulation GO:1903522 110 0.022
regulation of kinase activity GO:0043549 117 0.022
response to peptide hormone GO:0043434 278 0.022
signal release GO:0023061 145 0.022
regulation of apoptotic process GO:0042981 335 0.022
regulation of neuron projection development GO:0010975 161 0.022
cell differentiation involved in embryonic placenta development GO:0060706 1 0.022
positive regulation of signal transduction GO:0009967 175 0.022
cellular metal ion homeostasis GO:0006875 172 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
striated muscle cell differentiation GO:0051146 39 0.021
metal ion transport GO:0030001 289 0.021
response to estradiol GO:0032355 164 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
cell growth GO:0016049 104 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
oxoacid metabolic process GO:0043436 290 0.021
sensory organ development GO:0007423 74 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
cell cell signaling GO:0007267 335 0.021
organ regeneration GO:0031100 101 0.021
multi organism reproductive process GO:0044703 262 0.021
negative regulation of cell death GO:0060548 229 0.021
divalent inorganic cation transport GO:0072511 134 0.021
response to lipopolysaccharide GO:0032496 191 0.021
cation homeostasis GO:0055080 195 0.020
chemical homeostasis GO:0048878 292 0.020
regulation of cell cell adhesion GO:0022407 14 0.020
response to ethanol GO:0045471 162 0.020
hepaticobiliary system development GO:0061008 90 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
amide transport GO:0042886 105 0.020
regulation of rna metabolic process GO:0051252 391 0.020
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
response to growth factor GO:0070848 189 0.020
negative regulation of molecular function GO:0044092 133 0.020
renal system development GO:0072001 67 0.020
chromosome segregation GO:0007059 2 0.020
cellular ion homeostasis GO:0006873 184 0.020
regulation of neuron differentiation GO:0045664 208 0.020
cellular cation homeostasis GO:0030003 180 0.019
hormone secretion GO:0046879 115 0.019
intracellular transport GO:0046907 185 0.019
negative regulation of gene expression GO:0010629 199 0.019
single organism biosynthetic process GO:0044711 342 0.019
response to nutrient GO:0007584 248 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.019
cation transport GO:0006812 382 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
circulatory system process GO:0003013 183 0.019
regulation of cell motility GO:2000145 131 0.019
gastrulation GO:0007369 2 0.019
peptide transport GO:0015833 97 0.019
inflammatory response GO:0006954 150 0.019
response to reactive oxygen species GO:0000302 120 0.019
cellular response to corticosteroid stimulus GO:0071384 69 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
homeostatic process GO:0042592 331 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
cation transmembrane transport GO:0098655 263 0.018
regulation of protein modification process GO:0031399 194 0.018
regulation of neurogenesis GO:0050767 247 0.018
hormone transport GO:0009914 121 0.018
muscle tissue development GO:0060537 58 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
protein complex assembly GO:0006461 263 0.018
positive regulation of protein modification process GO:0031401 142 0.018
divalent metal ion transport GO:0070838 132 0.018
response to glucose GO:0009749 136 0.018
small molecule biosynthetic process GO:0044283 124 0.017
ion transmembrane transport GO:0034220 365 0.017
positive regulation of signaling GO:0023056 270 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of ion transport GO:0043269 245 0.017
regulation of ion transmembrane transport GO:0034765 121 0.017
cell activation GO:0001775 97 0.017
response to mechanical stimulus GO:0009612 134 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of cell development GO:0010720 176 0.017
response to radiation GO:0009314 137 0.017
negative regulation of developmental process GO:0051093 125 0.017
reactive oxygen species metabolic process GO:0072593 37 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
proteolysis GO:0006508 175 0.016
mesonephric tubule development GO:0072164 14 0.016
response to peptide GO:1901652 292 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
cellular catabolic process GO:0044248 295 0.016
response to biotic stimulus GO:0009607 226 0.016
tube development GO:0035295 89 0.016
immune system process GO:0002376 204 0.016
protein transport GO:0015031 132 0.016
embryo development ending in birth or egg hatching GO:0009792 22 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
regulation of transferase activity GO:0051338 123 0.015
mesonephric epithelium development GO:0072163 14 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
regulation of homotypic cell cell adhesion GO:0034110 4 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
regulation of muscle system process GO:0090257 79 0.015
anterior posterior pattern specification GO:0009952 1 0.015
regulation of calcium ion transport GO:0051924 77 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
sexual reproduction GO:0019953 148 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
regulation of peptide secretion GO:0002791 82 0.015
salivary gland development GO:0007431 3 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
leukocyte activation GO:0045321 76 0.015
gamete generation GO:0007276 124 0.015
sex differentiation GO:0007548 113 0.015
tongue morphogenesis GO:0043587 3 0.015
negative regulation of transport GO:0051051 136 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.014
response to vitamin GO:0033273 131 0.014
regulation of cellular component movement GO:0051270 150 0.014
multi multicellular organism process GO:0044706 138 0.014
regulation of hormone secretion GO:0046883 106 0.014
intracellular protein transport GO:0006886 79 0.014
male gamete generation GO:0048232 99 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
regulation of catabolic process GO:0009894 113 0.014
regulation of protein kinase activity GO:0045859 105 0.014
regulation of response to external stimulus GO:0032101 106 0.014
establishment of protein localization GO:0045184 141 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
regulation of body fluid levels GO:0050878 90 0.014
cell communication involved in cardiac conduction GO:0086065 2 0.014
cell part morphogenesis GO:0032990 123 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
cellular response to peptide GO:1901653 133 0.014
regulation of actin filament based process GO:0032970 42 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
cellular lipid metabolic process GO:0044255 208 0.014
rhythmic process GO:0048511 156 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
striated muscle cell development GO:0055002 26 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
cytoplasmic transport GO:0016482 115 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
ras protein signal transduction GO:0007265 29 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
organic acid biosynthetic process GO:0016053 83 0.013
regulation of mapk cascade GO:0043408 116 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
response to alkaloid GO:0043279 132 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
spindle organization GO:0007051 2 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
cellular macromolecular complex assembly GO:0034622 58 0.013
response to temperature stimulus GO:0009266 94 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
neuron projection morphogenesis GO:0048812 122 0.013
central nervous system development GO:0007417 311 0.013
regulation of protein transport GO:0051223 68 0.013
muscle contraction GO:0006936 88 0.013
single organismal cell cell adhesion GO:0016337 42 0.013
cellular calcium ion homeostasis GO:0006874 160 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
calcium ion homeostasis GO:0055074 162 0.012
sequestering of calcium ion GO:0051208 8 0.012
positive regulation of cell death GO:0010942 184 0.012
catabolic process GO:0009056 351 0.012
protein homooligomerization GO:0051260 91 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
axon development GO:0061564 96 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
cell adhesion GO:0007155 110 0.012
cellular response to hypoxia GO:0071456 51 0.012
mapk cascade GO:0000165 140 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
peptide hormone secretion GO:0030072 84 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
action potential GO:0001508 54 0.012
negative regulation of cell development GO:0010721 82 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of secretion by cell GO:1903530 208 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of secretion GO:0051046 224 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
muscle system process GO:0003012 115 0.012
head development GO:0060322 247 0.011
biological adhesion GO:0022610 110 0.011
development of primary sexual characteristics GO:0045137 107 0.011
defense response GO:0006952 194 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
cellular component movement GO:0006928 248 0.011
regulation of transmembrane transport GO:0034762 122 0.011
calcium ion transport GO:0006816 131 0.011
erythrocyte aggregation GO:0034117 1 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of protein localization GO:0032880 81 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
hepatocyte apoptotic process GO:0097284 3 0.011
gonad development GO:0008406 104 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
protein oligomerization GO:0051259 191 0.011
spermatogenesis GO:0007283 99 0.011
sensory perception GO:0007600 101 0.011
axis specification GO:0009798 4 0.011
salivary gland morphogenesis GO:0007435 1 0.011
regulation of cellular response to stress GO:0080135 49 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
cellular protein localization GO:0034613 122 0.011
single organism catabolic process GO:0044712 283 0.011
positive regulation of transferase activity GO:0051347 81 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
vesicle mediated transport GO:0016192 181 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
regulation of organelle organization GO:0033043 80 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
gland development GO:0048732 155 0.010
heterocycle catabolic process GO:0046700 167 0.010
brain development GO:0007420 247 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
regulation of cell projection organization GO:0031344 175 0.010
positive regulation of locomotion GO:0040017 102 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010

Krt18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.010
myopathy DOID:423 0 0.010
muscle tissue disease DOID:66 0 0.010