Rattus norvegicus

49 known processes

Tg

thyroglobulin

(Aliases: Tgn)

Tg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external biotic stimulus GO:0043207 221 0.227
reproductive process GO:0022414 372 0.215
response to biotic stimulus GO:0009607 226 0.204
response to other organism GO:0051707 220 0.189
response to carbohydrate GO:0009743 183 0.180
response to lipopolysaccharide GO:0032496 191 0.177
response to extracellular stimulus GO:0009991 380 0.139
regulation of signal transduction GO:0009966 318 0.138
homeostatic process GO:0042592 331 0.128
immune response GO:0006955 104 0.126
response to cytokine GO:0034097 215 0.119
response to monosaccharide GO:0034284 159 0.116
response to bacterium GO:0009617 200 0.112
response to organophosphorus GO:0046683 102 0.111
response to nutrient levels GO:0031667 370 0.100
cellular response to organonitrogen compound GO:0071417 197 0.100
multicellular organism reproduction GO:0032504 233 0.099
carbohydrate derivative metabolic process GO:1901135 346 0.094
response to hexose GO:0009746 144 0.092
regulation of molecular function GO:0065009 398 0.085
regulation of transcription dna templated GO:0006355 374 0.082
response to molecule of bacterial origin GO:0002237 194 0.082
cellular homeostasis GO:0019725 252 0.082
response to oxygen levels GO:0070482 265 0.082
regulation of phosphate metabolic process GO:0019220 349 0.078
positive regulation of molecular function GO:0044093 230 0.071
response to ketone GO:1901654 182 0.070
response to activity GO:0014823 73 0.068
regulation of apoptotic process GO:0042981 335 0.068
sensory perception GO:0007600 101 0.068
mapk cascade GO:0000165 140 0.067
transmembrane transport GO:0055085 412 0.064
response to hypoxia GO:0001666 231 0.063
steroid biosynthetic process GO:0006694 48 0.063
cellular ion homeostasis GO:0006873 184 0.063
rhythmic process GO:0048511 156 0.061
regulation of system process GO:0044057 208 0.059
cellular response to oxygen containing compound GO:1901701 386 0.059
secretion by cell GO:0032940 248 0.059
positive regulation of phosphate metabolic process GO:0045937 262 0.058
programmed cell death GO:0012501 392 0.057
calcium ion import GO:0070509 22 0.057
negative regulation of gene expression GO:0010629 199 0.057
response to decreased oxygen levels GO:0036293 237 0.056
divalent metal ion transport GO:0070838 132 0.056
response to retinoic acid GO:0032526 63 0.056
metal ion transport GO:0030001 289 0.055
cation homeostasis GO:0055080 195 0.055
nucleobase containing small molecule metabolic process GO:0055086 316 0.054
regulation of rna biosynthetic process GO:2001141 381 0.054
cation transport GO:0006812 382 0.054
reproduction GO:0000003 245 0.054
multi organism reproductive process GO:0044703 262 0.053
protein phosphorylation GO:0006468 345 0.053
cellular response to organic cyclic compound GO:0071407 202 0.052
divalent inorganic cation homeostasis GO:0072507 165 0.051
chemical homeostasis GO:0048878 292 0.051
negative regulation of metabolic process GO:0009892 331 0.051
regulation of phosphorylation GO:0042325 248 0.051
signal transduction by phosphorylation GO:0023014 144 0.050
regulation of ion transport GO:0043269 245 0.050
growth GO:0040007 165 0.050
positive regulation of cell communication GO:0010647 271 0.050
rna metabolic process GO:0016070 406 0.050
positive regulation of biosynthetic process GO:0009891 319 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
immune system process GO:0002376 204 0.048
aging GO:0007568 241 0.048
cellular response to steroid hormone stimulus GO:0071383 93 0.048
regulation of cellular localization GO:0060341 263 0.046
negative regulation of molecular function GO:0044092 133 0.046
apoptotic process GO:0006915 381 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
signal release GO:0023061 145 0.043
metal ion homeostasis GO:0055065 186 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.043
cellular response to external stimulus GO:0071496 118 0.043
cellular chemical homeostasis GO:0055082 247 0.043
regulation of protein kinase activity GO:0045859 105 0.042
transcription dna templated GO:0006351 377 0.042
response to peptide GO:1901652 292 0.041
reproductive system development GO:0061458 128 0.041
single organism biosynthetic process GO:0044711 342 0.040
negative regulation of transport GO:0051051 136 0.040
response to estradiol GO:0032355 164 0.040
regulation of secretion GO:0051046 224 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.038
protein homooligomerization GO:0051260 91 0.037
regulation of mapk cascade GO:0043408 116 0.037
cellular divalent inorganic cation homeostasis GO:0072503 162 0.037
regulation of protein phosphorylation GO:0001932 183 0.037
regulation of programmed cell death GO:0043067 341 0.037
response to camp GO:0051591 91 0.037
response to acid chemical GO:0001101 222 0.036
carboxylic acid transport GO:0046942 115 0.036
regulation of catalytic activity GO:0050790 304 0.036
positive regulation of phosphorylation GO:0042327 177 0.036
cellular cation homeostasis GO:0030003 180 0.036
neuron differentiation GO:0030182 368 0.035
inorganic cation transmembrane transport GO:0098662 202 0.035
positive regulation of neurogenesis GO:0050769 165 0.035
purine nucleotide biosynthetic process GO:0006164 83 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
positive regulation of mapk cascade GO:0043410 92 0.035
detection of visible light GO:0009584 3 0.033
negative regulation of apoptotic process GO:0043066 181 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.032
protein oligomerization GO:0051259 191 0.032
single organism reproductive process GO:0044702 297 0.032
ion homeostasis GO:0050801 212 0.032
negative regulation of transcription dna templated GO:0045892 116 0.031
hormone metabolic process GO:0042445 69 0.031
calcium ion homeostasis GO:0055074 162 0.031
positive regulation of intracellular signal transduction GO:1902533 138 0.030
intracellular signal transduction GO:0035556 314 0.030
vascular process in circulatory system GO:0003018 96 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
calcitriol biosynthetic process from calciol GO:0036378 2 0.029
response to glucose GO:0009749 136 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
positive regulation of transport GO:0051050 245 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
calcium ion transport GO:0006816 131 0.027
response to corticosteroid GO:0031960 235 0.027
organic acid transport GO:0015849 116 0.027
organic hydroxy compound metabolic process GO:1901615 115 0.027
cation transmembrane transport GO:0098655 263 0.027
multi multicellular organism process GO:0044706 138 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
negative regulation of cell proliferation GO:0008285 119 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
regulation of cell differentiation GO:0045595 320 0.026
positive regulation of cell development GO:0010720 176 0.026
cell cell signaling GO:0007267 335 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
response to starvation GO:0042594 59 0.026
response to inorganic substance GO:0010035 377 0.026
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.025
single organism catabolic process GO:0044712 283 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
spermatogenesis GO:0007283 99 0.025
negative regulation of cell death GO:0060548 229 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.025
single organism intracellular transport GO:1902582 166 0.025
neurological system process GO:0050877 219 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
cellular amine metabolic process GO:0044106 38 0.025
negative regulation of signaling GO:0023057 157 0.024
regulation of nervous system development GO:0051960 264 0.024
Mouse
response to light stimulus GO:0009416 52 0.024
synaptic transmission GO:0007268 235 0.024
cellular response to stress GO:0033554 269 0.024
regulation of rna metabolic process GO:0051252 391 0.023
intracellular transport GO:0046907 185 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
cellular response to alkaloid GO:0071312 25 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of signal transduction GO:0009967 175 0.023
response to vitamin GO:0033273 131 0.023
regulation of camp biosynthetic process GO:0030817 38 0.023
rna biosynthetic process GO:0032774 380 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of calcium ion transport GO:0051924 77 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
positive regulation of protein metabolic process GO:0051247 178 0.022
developmental process involved in reproduction GO:0003006 159 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
cellular component biogenesis GO:0044085 368 0.022
response to reactive oxygen species GO:0000302 120 0.022
macromolecule catabolic process GO:0009057 58 0.022
regulation of tube size GO:0035150 89 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
cellular component movement GO:0006928 248 0.021
regulation of growth GO:0040008 105 0.021
regulation of synaptic plasticity GO:0048167 70 0.021
response to temperature stimulus GO:0009266 94 0.021
positive regulation of protein modification process GO:0031401 142 0.021
female pregnancy GO:0007565 122 0.021
divalent inorganic cation transport GO:0072511 134 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
Mouse
ion transmembrane transport GO:0034220 365 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
secretion GO:0046903 307 0.020
cellular ketone metabolic process GO:0042180 51 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
regulation of metal ion transport GO:0010959 118 0.020
positive regulation of signaling GO:0023056 270 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
neurotransmitter transport GO:0006836 42 0.020
purine ribonucleotide biosynthetic process GO:0009152 81 0.020
defense response GO:0006952 194 0.019
head development GO:0060322 247 0.019
brain development GO:0007420 247 0.019
response to insulin GO:0032868 133 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of ion transmembrane transport GO:0034765 121 0.019
steroid metabolic process GO:0008202 73 0.019
response to glucocorticoid GO:0051384 223 0.019
catabolic process GO:0009056 351 0.019
circadian rhythm GO:0007623 88 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
cellular response to lipid GO:0071396 201 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
regulation of anatomical structure size GO:0090066 135 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
response to estrogen GO:0043627 232 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of kinase activity GO:0043549 117 0.018
sensory perception of light stimulus GO:0050953 3 0.018
response to hydrogen peroxide GO:0042542 89 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
protein complex biogenesis GO:0070271 263 0.018
regulation of muscle system process GO:0090257 79 0.018
regulation of vesicle mediated transport GO:0060627 81 0.017
response to radiation GO:0009314 137 0.017
regulation of hormone levels GO:0010817 187 0.017
positive regulation of secretion GO:0051047 140 0.017
sensory perception of pain GO:0019233 73 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
positive regulation of protein kinase activity GO:0045860 73 0.017
organic substance catabolic process GO:1901575 316 0.017
negative regulation of signal transduction GO:0009968 83 0.017
regulation of transferase activity GO:0051338 123 0.017
nucleic acid templated transcription GO:0097659 379 0.017
reproductive structure development GO:0048608 128 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
protein tetramerization GO:0051262 38 0.016
circulatory system process GO:0003013 183 0.016
positive regulation of nervous system development GO:0051962 178 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
regulation of protein metabolic process GO:0051246 289 0.016
positive regulation of developmental process GO:0051094 283 0.016
positive regulation of kinase activity GO:0033674 77 0.016
vesicle mediated transport GO:0016192 181 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
cell type specific apoptotic process GO:0097285 134 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
regulation of neurogenesis GO:0050767 247 0.016
regulation of homeostatic process GO:0032844 101 0.016
neuron development GO:0048666 286 0.016
cellular component assembly GO:0022607 360 0.015
development of primary sexual characteristics GO:0045137 107 0.015
cell activation GO:0001775 97 0.015
synapse organization GO:0050808 46 0.015
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to growth factor GO:0070848 189 0.015
protein complex subunit organization GO:0071822 302 0.015
gamete generation GO:0007276 124 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
male gamete generation GO:0048232 99 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
anion transport GO:0006820 178 0.014
Mouse
organic acid metabolic process GO:0006082 292 0.014
isoprenoid metabolic process GO:0006720 45 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
protein complex assembly GO:0006461 263 0.014
developmental growth GO:0048589 100 0.014
purine containing compound metabolic process GO:0072521 253 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
macromolecule localization GO:0033036 252 0.014
defense response to gram negative bacterium GO:0050829 3 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of ion transport GO:0043270 94 0.013
regulation of transmembrane transport GO:0034762 122 0.013
defense response to gram positive bacterium GO:0050830 2 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
lipid storage GO:0019915 1 0.013
single organism behavior GO:0044708 130 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
response to nutrient GO:0007584 248 0.013
immune effector process GO:0002252 53 0.013
detection of external stimulus GO:0009581 13 0.013
development of primary male sexual characteristics GO:0046546 59 0.013
regulation of immune system process GO:0002682 123 0.013
negative regulation of dopamine secretion GO:0033602 4 0.013
gonad development GO:0008406 104 0.013
regulation of secretion by cell GO:1903530 208 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
behavior GO:0007610 205 0.012
vitamin d metabolic process GO:0042359 4 0.012
regulation of membrane potential GO:0042391 110 0.012
response to peptide hormone GO:0043434 278 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
somatostatin receptor signaling pathway GO:0038169 4 0.012
nucleotide metabolic process GO:0009117 279 0.012
response to alkaloid GO:0043279 132 0.012
oxidation reduction process GO:0055114 304 0.012
cellular response to histamine GO:0071420 3 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.012
regulation of cellular component organization GO:0051128 368 0.012
sex differentiation GO:0007548 113 0.012
positive regulation of synaptic transmission GO:0050806 62 0.012
regulation of chronic inflammatory response GO:0002676 3 0.012
positive regulation of immune system process GO:0002684 90 0.011
response to toxic substance GO:0009636 133 0.011
ovulation cycle GO:0042698 67 0.011
response to wounding GO:0009611 254 0.011
negative regulation of proteolysis GO:0045861 41 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
alcohol metabolic process GO:0006066 77 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
response to food GO:0032094 27 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
sexual reproduction GO:0019953 148 0.011
organelle organization GO:0006996 266 0.011
cellular response to ketone GO:1901655 51 0.011
somatostatin signaling pathway GO:0038170 4 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
amine metabolic process GO:0009308 38 0.011
regulation of protein modification process GO:0031399 194 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
dna metabolic process GO:0006259 96 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
axis specification GO:0009798 4 0.011
detection of stimulus involved in sensory perception GO:0050906 16 0.010
sensory perception of bitter taste GO:0050913 4 0.010
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
cell growth GO:0016049 104 0.010
response to electrical stimulus GO:0051602 56 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
response to testosterone GO:0033574 55 0.010
negative regulation of cell communication GO:0010648 158 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.010
salivary gland development GO:0007431 3 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
nitrogen compound transport GO:0071705 229 0.010
blood circulation GO:0008015 183 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
coronary vasculature morphogenesis GO:0060977 3 0.010
visual perception GO:0007601 3 0.010
protein autophosphorylation GO:0046777 66 0.010

Tg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.137
sensory system disease DOID:0050155 0 0.137
disease of anatomical entity DOID:7 0 0.137
eye and adnexa disease DOID:1492 0 0.137
nervous system disease DOID:863 0 0.137
eye disease DOID:5614 0 0.137
kidney disease DOID:557 0 0.035
urinary system disease DOID:18 0 0.035
night blindness DOID:8499 0 0.011