Rattus norvegicus

0 known processes

Flcn

folliculin

(Aliases: MGC94558,Bhd)

Flcn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.126
catabolic process GO:0009056 351 0.120
intracellular signal transduction GO:0035556 314 0.096
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.095
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.092
Mouse
response to extracellular stimulus GO:0009991 380 0.084
response to nutrient levels GO:0031667 370 0.081
regulation of protein metabolic process GO:0051246 289 0.078
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.077
Mouse
regulation of molecular function GO:0065009 398 0.071
single organism catabolic process GO:0044712 283 0.070
regulation of cellular protein metabolic process GO:0032268 267 0.065
Mouse
organelle organization GO:0006996 266 0.062
Mouse
neuron differentiation GO:0030182 368 0.061
negative regulation of metabolic process GO:0009892 331 0.058
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.058
Mouse
regulation of signal transduction GO:0009966 318 0.055
Mouse
regulation of cellular catabolic process GO:0031329 101 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
regulation of catalytic activity GO:0050790 304 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.044
Mouse
protein phosphorylation GO:0006468 345 0.044
Mouse
regulation of catabolic process GO:0009894 113 0.042
cellular amine metabolic process GO:0044106 38 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.042
Mouse
organophosphate metabolic process GO:0019637 370 0.042
Mouse
regulation of protein phosphorylation GO:0001932 183 0.041
Mouse
organic acid metabolic process GO:0006082 292 0.041
regulation of phosphorylation GO:0042325 248 0.041
Mouse
macromolecular complex assembly GO:0065003 273 0.039
regulation of transferase activity GO:0051338 123 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
apoptotic process GO:0006915 381 0.036
Mouse
macromolecular complex subunit organization GO:0043933 339 0.036
Mouse
protein complex assembly GO:0006461 263 0.036
response to nutrient GO:0007584 248 0.035
cellular response to stress GO:0033554 269 0.035
response to peptide GO:1901652 292 0.034
nucleoside phosphate metabolic process GO:0006753 283 0.034
Mouse
organic anion transport GO:0015711 132 0.033
cellular component biogenesis GO:0044085 368 0.033
Mouse
organic substance catabolic process GO:1901575 316 0.033
organic acid transport GO:0015849 116 0.033
negative regulation of cell death GO:0060548 229 0.032
multicellular organism growth GO:0035264 1 0.032
positive regulation of gene expression GO:0010628 244 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
Mouse
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.031
Mouse
positive regulation of molecular function GO:0044093 230 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.029
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
rna biosynthetic process GO:0032774 380 0.029
Mouse
cellular ketone metabolic process GO:0042180 51 0.029
neuron projection development GO:0031175 273 0.028
regulation of cell differentiation GO:0045595 320 0.028
Mouse
carboxylic acid metabolic process GO:0019752 289 0.028
cellular response to oxygen containing compound GO:1901701 386 0.027
regulation of cellular component organization GO:0051128 368 0.027
Mouse
programmed cell death GO:0012501 392 0.027
Mouse
regulation of cell development GO:0060284 263 0.027
anterior posterior pattern specification GO:0009952 1 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
Mouse
single organism reproductive process GO:0044702 297 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
Mouse
regulation of programmed cell death GO:0043067 341 0.025
Mouse
nucleotide metabolic process GO:0009117 279 0.025
Mouse
negative regulation of programmed cell death GO:0043069 183 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
amine metabolic process GO:0009308 38 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
Mouse
organophosphate catabolic process GO:0046434 148 0.024
intracellular transport GO:0046907 185 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
Mouse
negative regulation of gene expression GO:0010629 199 0.024
Mouse
carbohydrate derivative catabolic process GO:1901136 147 0.024
response to decreased oxygen levels GO:0036293 237 0.024
response to hypoxia GO:0001666 231 0.024
regulation of neurogenesis GO:0050767 247 0.024
reproductive process GO:0022414 372 0.023
cellular lipid metabolic process GO:0044255 208 0.023
protein complex subunit organization GO:0071822 302 0.023
nucleic acid templated transcription GO:0097659 379 0.023
Mouse
response to peptide hormone GO:0043434 278 0.023
positive regulation of cell development GO:0010720 176 0.023
response to starvation GO:0042594 59 0.023
single organism organelle organization GO:1902589 180 0.023
Mouse
regulation of protein kinase activity GO:0045859 105 0.022
positive regulation of protein modification process GO:0031401 142 0.022
Mouse
macromolecule localization GO:0033036 252 0.022
regulation of kinase activity GO:0043549 117 0.022
ribonucleoside triphosphate metabolic process GO:0009199 141 0.022
Mouse
regulation of protein modification process GO:0031399 194 0.022
Mouse
negative regulation of cell communication GO:0010648 158 0.022
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.022
Mouse
regulation of nervous system development GO:0051960 264 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
Mouse
regulation of rna metabolic process GO:0051252 391 0.021
Mouse
transcription dna templated GO:0006351 377 0.021
Mouse
positive regulation of phosphorylation GO:0042327 177 0.021
Mouse
response to oxygen levels GO:0070482 265 0.021
carboxylic acid transport GO:0046942 115 0.021
regulation of neuron differentiation GO:0045664 208 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
single organism biosynthetic process GO:0044711 342 0.021
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
Mouse
cell projection organization GO:0030030 302 0.021
cell cycle GO:0007049 101 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
Mouse
anion transport GO:0006820 178 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
positive regulation of cellular catabolic process GO:0031331 71 0.021
regulation of apoptotic process GO:0042981 335 0.021
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.021
cation transport GO:0006812 382 0.020
monocarboxylic acid transport GO:0015718 52 0.020
protein complex biogenesis GO:0070271 263 0.020
homeostatic process GO:0042592 331 0.020
Mouse
regulation of cell proliferation GO:0042127 359 0.020
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.019
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
response to growth factor GO:0070848 189 0.019
Mouse
cellular component assembly GO:0022607 360 0.019
Mouse
positive regulation of developmental process GO:0051094 283 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
Mouse
multicellular organismal reproductive process GO:0048609 233 0.019
aromatic compound catabolic process GO:0019439 168 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.018
lipid metabolic process GO:0006629 283 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
Mouse
nucleotide catabolic process GO:0009166 139 0.018
central nervous system development GO:0007417 311 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
Mouse
response to hexose GO:0009746 144 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
Mouse
regulation of transcription dna templated GO:0006355 374 0.018
Mouse
oxoacid metabolic process GO:0043436 290 0.018
purine containing compound metabolic process GO:0072521 253 0.017
Mouse
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
Mouse
cellular response to nitrogen compound GO:1901699 210 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
positive regulation of nervous system development GO:0051962 178 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
mapk cascade GO:0000165 140 0.017
Mouse
nucleoside catabolic process GO:0009164 126 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
Mouse
positive regulation of catalytic activity GO:0043085 184 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
axis specification GO:0009798 4 0.017
single organism intracellular transport GO:1902582 166 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
Mouse
positive regulation of catabolic process GO:0009896 78 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
Mouse
response to ethanol GO:0045471 162 0.016
amide transport GO:0042886 105 0.016
chemical homeostasis GO:0048878 292 0.016
reproduction GO:0000003 245 0.016
ras protein signal transduction GO:0007265 29 0.016
cellular response to lipid GO:0071396 201 0.016
regulation of mapk cascade GO:0043408 116 0.016
Mouse
positive regulation of protein kinase activity GO:0045860 73 0.016
rhythmic process GO:0048511 156 0.016
organonitrogen compound catabolic process GO:1901565 179 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
Mouse
protein localization GO:0008104 191 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
transmembrane transport GO:0055085 412 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
Mouse
protein oligomerization GO:0051259 191 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cell morphogenesis GO:0000902 142 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
Mouse
metal ion transport GO:0030001 289 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.015
Mouse
purine containing compound catabolic process GO:0072523 138 0.015
response to acid chemical GO:0001101 222 0.015
positive regulation of signaling GO:0023056 270 0.015
Mouse
regulation of anatomical structure size GO:0090066 135 0.015
chromatin modification GO:0016568 33 0.015
Mouse
peptidyl amino acid modification GO:0018193 126 0.014
Mouse
heterocycle catabolic process GO:0046700 167 0.014
nucleoside metabolic process GO:0009116 179 0.014
Mouse
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
Mouse
regulation of growth GO:0040008 105 0.014
autophagy GO:0006914 19 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
response to ketone GO:1901654 182 0.014
aging GO:0007568 241 0.014
chromatin organization GO:0006325 34 0.014
Mouse
multi organism reproductive process GO:0044703 262 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
cytoplasmic transport GO:0016482 115 0.014
glycosyl compound catabolic process GO:1901658 126 0.013
brain development GO:0007420 247 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
Mouse
response to carbohydrate GO:0009743 183 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of neuron projection development GO:0010975 161 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
growth GO:0040007 165 0.013
negative regulation of transport GO:0051051 136 0.013
gastrulation GO:0007369 2 0.013
rna metabolic process GO:0016070 406 0.013
Mouse
positive regulation of kinase activity GO:0033674 77 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
protein heterooligomerization GO:0051291 89 0.013
cation transmembrane transport GO:0098655 263 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
Mouse
small molecule biosynthetic process GO:0044283 124 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
Mouse
ribonucleoside catabolic process GO:0042454 126 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
Mouse
response to inorganic substance GO:0010035 377 0.013
positive regulation of neuron projection development GO:0010976 99 0.012
spermatogenesis GO:0007283 99 0.012
cellular protein localization GO:0034613 122 0.012
chromosome organization GO:0051276 36 0.012
Mouse
organic hydroxy compound metabolic process GO:1901615 115 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
Mouse
oxidation reduction process GO:0055114 304 0.012
Mouse
glycerolipid metabolic process GO:0046486 67 0.012
regulation of cell projection organization GO:0031344 175 0.012
neuron development GO:0048666 286 0.012
regulation of hydrolase activity GO:0051336 143 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
proteolysis GO:0006508 175 0.012
neuron projection morphogenesis GO:0048812 122 0.012
gamete generation GO:0007276 124 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of response to stress GO:0080134 126 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
cellular response to external stimulus GO:0071496 118 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
Mouse
regulation of lipid metabolic process GO:0019216 68 0.011
phospholipid metabolic process GO:0006644 61 0.011
secretion GO:0046903 307 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
Mouse
response to oxidative stress GO:0006979 186 0.011
hepaticobiliary system development GO:0061008 90 0.011
response to purine containing compound GO:0014074 126 0.011
response to glucose GO:0009749 136 0.011
positive regulation of cell death GO:0010942 184 0.011
Mouse
macroautophagy GO:0016236 4 0.011
negative regulation of signaling GO:0023057 157 0.011
Mouse
cation homeostasis GO:0055080 195 0.011
developmental growth GO:0048589 100 0.011
cardiovascular system development GO:0072358 134 0.011
gland development GO:0048732 155 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
regulation of system process GO:0044057 208 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
cell projection morphogenesis GO:0048858 123 0.010
circulatory system process GO:0003013 183 0.010
cellular response to peptide GO:1901653 133 0.010
regulation of membrane potential GO:0042391 110 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
lipid biosynthetic process GO:0008610 128 0.010
cellular response to alcohol GO:0097306 87 0.010
negative regulation of developmental process GO:0051093 125 0.010
Mouse
response to insulin GO:0032868 133 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
Mouse
ion transmembrane transport GO:0034220 365 0.010

Flcn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.013
nervous system disease DOID:863 0 0.013
myopathy DOID:423 0 0.013