Rattus norvegicus

8 known processes

Unc13d

unc-13 homolog D (C. elegans)

(Aliases: Munc13-4,Unc13h4)

Unc13d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein phosphorylation GO:0006468 345 0.217
regulation of immune system process GO:0002682 123 0.172
Human
cellular response to lipid GO:0071396 201 0.122
immune response GO:0006955 104 0.121
Human Mouse
protein complex subunit organization GO:0071822 302 0.109
negative regulation of metabolic process GO:0009892 331 0.101
response to extracellular stimulus GO:0009991 380 0.091
negative regulation of neuron differentiation GO:0045665 62 0.084
response to biotic stimulus GO:0009607 226 0.081
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.078
cell migration GO:0016477 197 0.078
regulation of cellular component organization GO:0051128 368 0.069
response to cytokine GO:0034097 215 0.065
cell projection organization GO:0030030 302 0.065
intracellular signal transduction GO:0035556 314 0.062
localization of cell GO:0051674 202 0.060
neuron differentiation GO:0030182 368 0.060
positive regulation of cell death GO:0010942 184 0.060
regulation of multicellular organismal development GO:2000026 376 0.060
regulation of response to stress GO:0080134 126 0.059
regulation of response to external stimulus GO:0032101 106 0.058
cation transport GO:0006812 382 0.056
cell motility GO:0048870 202 0.056
lipid metabolic process GO:0006629 283 0.055
aging GO:0007568 241 0.054
regulation of protein phosphorylation GO:0001932 183 0.053
positive regulation of cell proliferation GO:0008284 249 0.051
regulation of phosphorylation GO:0042325 248 0.048
head development GO:0060322 247 0.047
regulation of phosphorus metabolic process GO:0051174 349 0.046
positive regulation of protein modification process GO:0031401 142 0.045
transcription dna templated GO:0006351 377 0.045
organic cyclic compound catabolic process GO:1901361 175 0.044
response to wounding GO:0009611 254 0.044
regulation of molecular function GO:0065009 398 0.044
lymphocyte activation GO:0046649 43 0.043
Mouse
regulation of synaptic transmission GO:0050804 141 0.043
response to nutrient levels GO:0031667 370 0.043
response to oxygen levels GO:0070482 265 0.042
cell chemotaxis GO:0060326 31 0.042
positive regulation of multicellular organismal process GO:0051240 387 0.041
positive regulation of immune system process GO:0002684 90 0.041
Human
regulation of phosphate metabolic process GO:0019220 349 0.040
response to temperature stimulus GO:0009266 94 0.039
cellular response to acid chemical GO:0071229 75 0.039
cellular component assembly GO:0022607 360 0.039
positive regulation of cellular component movement GO:0051272 102 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.038
cell activation GO:0001775 97 0.038
Human Mouse
regulation of protein modification process GO:0031399 194 0.037
rna biosynthetic process GO:0032774 380 0.036
cellular response to organic cyclic compound GO:0071407 202 0.036
leukocyte activation GO:0045321 76 0.035
Human Mouse
response to acid chemical GO:0001101 222 0.034
regulation of transcription dna templated GO:0006355 374 0.034
positive regulation of developmental process GO:0051094 283 0.034
cellular component movement GO:0006928 248 0.033
cellular ketone metabolic process GO:0042180 51 0.033
guanosine containing compound metabolic process GO:1901068 74 0.033
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.033
cellular component biogenesis GO:0044085 368 0.032
negative regulation of immune system process GO:0002683 39 0.032
immune effector process GO:0002252 53 0.032
Human Mouse
positive regulation of cellular component organization GO:0051130 200 0.032
calcium ion homeostasis GO:0055074 162 0.032
single organism reproductive process GO:0044702 297 0.032
positive regulation of phosphorylation GO:0042327 177 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
central nervous system development GO:0007417 311 0.031
purine nucleotide metabolic process GO:0006163 229 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
brain development GO:0007420 247 0.030
regulation of ion transport GO:0043269 245 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
regulation of neurogenesis GO:0050767 247 0.030
neuron projection development GO:0031175 273 0.029
anterior posterior pattern specification GO:0009952 1 0.029
transmembrane transport GO:0055085 412 0.029
divalent metal ion transport GO:0070838 132 0.028
innate immune response GO:0045087 35 0.028
Mouse
neuron neuron synaptic transmission GO:0007270 60 0.028
leukocyte migration GO:0050900 38 0.028
positive regulation of cell differentiation GO:0045597 217 0.027
negative regulation of cell communication GO:0010648 158 0.027
response to inorganic substance GO:0010035 377 0.027
endocytosis GO:0006897 84 0.027
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.027
cellular catabolic process GO:0044248 295 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
purine containing compound catabolic process GO:0072523 138 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.026
catabolic process GO:0009056 351 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
neuron development GO:0048666 286 0.026
regulation of nervous system development GO:0051960 264 0.026
reproductive process GO:0022414 372 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
eye morphogenesis GO:0048592 4 0.026
regulation of cytokine production GO:0001817 56 0.026
response to external biotic stimulus GO:0043207 221 0.026
Mouse
axis specification GO:0009798 4 0.026
metal ion transport GO:0030001 289 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
negative regulation of nervous system development GO:0051961 79 0.025
regulation of defense response GO:0031347 68 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
cellular response to stress GO:0033554 269 0.025
response to decreased oxygen levels GO:0036293 237 0.025
response to peptide hormone GO:0043434 278 0.025
organophosphate metabolic process GO:0019637 370 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
regulation of response to wounding GO:1903034 69 0.024
ras protein signal transduction GO:0007265 29 0.024
memory GO:0007613 54 0.024
negative regulation of cell development GO:0010721 82 0.024
positive regulation of transport GO:0051050 245 0.024
Human
cellular response to hormone stimulus GO:0032870 247 0.023
negative regulation of innate immune response GO:0045824 4 0.023
transmission of nerve impulse GO:0019226 42 0.023
immune system process GO:0002376 204 0.023
Human Mouse
multi organism reproductive process GO:0044703 262 0.023
negative regulation of cell differentiation GO:0045596 99 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
cell growth GO:0016049 104 0.022
positive regulation of cell development GO:0010720 176 0.022
regulation of cell motility GO:2000145 131 0.022
regulation of cell differentiation GO:0045595 320 0.022
action potential GO:0001508 54 0.022
programmed cell death GO:0012501 392 0.022
interleukin 18 production GO:0032621 1 0.021
regeneration GO:0031099 163 0.021
cellular response to glucocorticoid stimulus GO:0071385 68 0.021
cell cycle GO:0007049 101 0.021
regulation of hydrolase activity GO:0051336 143 0.021
positive regulation of protein kinase activity GO:0045860 73 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
regulation of cell projection organization GO:0031344 175 0.021
single organism biosynthetic process GO:0044711 342 0.021
gtp catabolic process GO:0006184 71 0.021
aromatic compound catabolic process GO:0019439 168 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
behavior GO:0007610 205 0.021
organelle organization GO:0006996 266 0.020
defense response to gram positive bacterium GO:0050830 2 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
apoptotic process GO:0006915 381 0.020
response to corticosteroid GO:0031960 235 0.020
cellular homeostasis GO:0019725 252 0.020
gtp metabolic process GO:0046039 72 0.020
establishment of protein localization GO:0045184 141 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
positive regulation of nervous system development GO:0051962 178 0.020
mononuclear cell proliferation GO:0032943 29 0.020
nucleic acid templated transcription GO:0097659 379 0.020
regulation of catabolic process GO:0009894 113 0.020
homeostatic process GO:0042592 331 0.020
response to estradiol GO:0032355 164 0.020
positive regulation of cell migration GO:0030335 96 0.020
liver development GO:0001889 90 0.020
regulation of cell development GO:0060284 263 0.019
response to hypoxia GO:0001666 231 0.019
positive regulation of gene expression GO:0010628 244 0.019
regulation of locomotion GO:0040012 148 0.019
regulation of cell migration GO:0030334 128 0.019
protein complex assembly GO:0006461 263 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
positive regulation of response to external stimulus GO:0032103 51 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
regulation of catalytic activity GO:0050790 304 0.019
regulation of nucleotide catabolic process GO:0030811 65 0.019
macromolecular complex assembly GO:0065003 273 0.019
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
response to lipopolysaccharide GO:0032496 191 0.019
regulation of ras gtpase activity GO:0032318 32 0.018
positive regulation of gtp catabolic process GO:0033126 48 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
cytoskeleton organization GO:0007010 111 0.018
cytokine production GO:0001816 61 0.018
taxis GO:0042330 67 0.018
sexual reproduction GO:0019953 148 0.018
muscle system process GO:0003012 115 0.018
chemical homeostasis GO:0048878 292 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
oxidation reduction process GO:0055114 304 0.018
regulation of protein metabolic process GO:0051246 289 0.018
gland development GO:0048732 155 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.017
multicellular organism reproduction GO:0032504 233 0.017
hepaticobiliary system development GO:0061008 90 0.017
peptidyl tyrosine phosphorylation GO:0018108 72 0.017
lymphocyte proliferation GO:0046651 29 0.017
macromolecule localization GO:0033036 252 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
protein localization GO:0008104 191 0.017
learning or memory GO:0007611 90 0.017
regulation of cytoskeleton organization GO:0051493 49 0.017
nucleoside catabolic process GO:0009164 126 0.017
regulation of apoptotic process GO:0042981 335 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
positive regulation of defense response GO:0031349 37 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.016
rna metabolic process GO:0016070 406 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
purine containing compound metabolic process GO:0072521 253 0.016
vesicle mediated transport GO:0016192 181 0.016
Human Mouse
small gtpase mediated signal transduction GO:0007264 36 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
heterocycle catabolic process GO:0046700 167 0.016
nucleotide metabolic process GO:0009117 279 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
axon development GO:0061564 96 0.016
sensory perception of pain GO:0019233 73 0.016
mesoderm development GO:0007498 2 0.016
negative regulation of signaling GO:0023057 157 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of jnk cascade GO:0046330 13 0.015
inflammatory response GO:0006954 150 0.015
Mouse
single organism organelle organization GO:1902589 180 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
guanosine containing compound catabolic process GO:1901069 71 0.015
regulation of cell adhesion GO:0030155 52 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
response to metal ion GO:0010038 253 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
regulation of gtpase activity GO:0043087 57 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
regulation of protein kinase activity GO:0045859 105 0.014
calcium ion transport GO:0006816 131 0.014
response to heat GO:0009408 60 0.014
hemopoiesis GO:0030097 34 0.014
response to oxidative stress GO:0006979 186 0.014
cell adhesion GO:0007155 110 0.014
regulation of secretion by cell GO:1903530 208 0.014
Human
telencephalon development GO:0021537 62 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
growth GO:0040007 165 0.014
axonogenesis GO:0007409 71 0.014
regulation of behavior GO:0050795 61 0.014
response to mechanical stimulus GO:0009612 134 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
secretion by cell GO:0032940 248 0.014
Human Mouse
response to bacterium GO:0009617 200 0.014
response to estrogen GO:0043627 232 0.014
regulation of calcium ion transport GO:0051924 77 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
regulation of signal transduction GO:0009966 318 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of immune response GO:0050776 55 0.014
Human
cellular protein localization GO:0034613 122 0.014
cellular response to corticosteroid stimulus GO:0071384 69 0.013
regulation of mononuclear cell proliferation GO:0032944 26 0.013
regulation of gtp catabolic process GO:0033124 58 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
protein transport GO:0015031 132 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
cellular lipid metabolic process GO:0044255 208 0.013
oxoacid metabolic process GO:0043436 290 0.013
negative regulation of transport GO:0051051 136 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
negative regulation of neuron projection development GO:0010977 46 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
neurological system process GO:0050877 219 0.013
response to nutrient GO:0007584 248 0.013
protein complex biogenesis GO:0070271 263 0.013
response to hexose GO:0009746 144 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
organic substance catabolic process GO:1901575 316 0.013
gastrulation GO:0007369 2 0.013
regulation of organic acid transport GO:0032890 35 0.013
nucleoside metabolic process GO:0009116 179 0.013
phasic smooth muscle contraction GO:0014821 3 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
regulation of kinase activity GO:0043549 117 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
myeloid cell differentiation GO:0030099 22 0.013
neuron projection morphogenesis GO:0048812 122 0.013
morphogenesis of an epithelium GO:0002009 20 0.013
regulation of epithelial to mesenchymal transition GO:0010717 2 0.013
circadian rhythm GO:0007623 88 0.012
cellular chemical homeostasis GO:0055082 247 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
erythrocyte differentiation GO:0030218 1 0.012
retinal ganglion cell axon guidance GO:0031290 1 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
lipid storage GO:0019915 1 0.012
positive regulation of ras gtpase activity GO:0032320 28 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
positive regulation of gtpase activity GO:0043547 47 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
eye development GO:0001654 50 0.012
cell type specific apoptotic process GO:0097285 134 0.012
organophosphate catabolic process GO:0046434 148 0.012
kidney morphogenesis GO:0060993 13 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
regulation of membrane potential GO:0042391 110 0.012
response to other organism GO:0051707 220 0.012
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.012
embryonic pattern specification GO:0009880 1 0.012
response to axon injury GO:0048678 59 0.012
single organism behavior GO:0044708 130 0.011
reproduction GO:0000003 245 0.011
regulation of endocytosis GO:0030100 42 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
response to insulin GO:0032868 133 0.011
regulation of leukocyte proliferation GO:0070663 26 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
activation of protein kinase activity GO:0032147 47 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of programmed cell death GO:0043067 341 0.011
organ regeneration GO:0031100 101 0.011
inflammatory response to antigenic stimulus GO:0002437 18 0.011
cellular response to oxygen levels GO:0071453 60 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of cell projection organization GO:0031345 50 0.011
response to ketone GO:1901654 182 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cognition GO:0050890 92 0.011
regulation of actin cytoskeleton organization GO:0032956 30 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of rna metabolic process GO:0051252 391 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
interferon gamma production GO:0032609 3 0.010
regulation of protein transport GO:0051223 68 0.010
ion transmembrane transport GO:0034220 365 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
positive regulation of kinase activity GO:0033674 77 0.010
regulation of growth GO:0040008 105 0.010
cell cycle checkpoint GO:0000075 2 0.010
dephosphorylation GO:0016311 98 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
regulation of transferase activity GO:0051338 123 0.010
response to radiation GO:0009314 137 0.010
neuron death GO:0070997 127 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
negative regulation of gene expression GO:0010629 199 0.010
rho protein signal transduction GO:0007266 11 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
secretion GO:0046903 307 0.010
metanephric renal vesicle morphogenesis GO:0072283 3 0.010

Unc13d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org