Rattus norvegicus

0 known processes

Cldn12

claudin 12

(Aliases: RGD1561053)

Cldn12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.068
carboxylic acid metabolic process GO:0019752 289 0.062
organic acid metabolic process GO:0006082 292 0.059
cell cell signaling GO:0007267 335 0.055
cellular amino acid metabolic process GO:0006520 107 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
neuron development GO:0048666 286 0.039
regulation of phosphate metabolic process GO:0019220 349 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
cellular response to stress GO:0033554 269 0.036
response to inorganic substance GO:0010035 377 0.035
neuron differentiation GO:0030182 368 0.035
negative regulation of metabolic process GO:0009892 331 0.035
intracellular signal transduction GO:0035556 314 0.034
cellular amine metabolic process GO:0044106 38 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
regulation of cellular component organization GO:0051128 368 0.033
regulation of catalytic activity GO:0050790 304 0.033
rna biosynthetic process GO:0032774 380 0.032
single organism biosynthetic process GO:0044711 342 0.032
nucleic acid templated transcription GO:0097659 379 0.032
protein phosphorylation GO:0006468 345 0.031
purine containing compound metabolic process GO:0072521 253 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
amine metabolic process GO:0009308 38 0.030
transcription dna templated GO:0006351 377 0.030
cellular ketone metabolic process GO:0042180 51 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
homeostatic process GO:0042592 331 0.029
cellular response to endogenous stimulus GO:0071495 377 0.028
regulation of cell differentiation GO:0045595 320 0.028
catabolic process GO:0009056 351 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
rna metabolic process GO:0016070 406 0.028
single organism catabolic process GO:0044712 283 0.027
central nervous system development GO:0007417 311 0.027
regulation of programmed cell death GO:0043067 341 0.027
regulation of signal transduction GO:0009966 318 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
regulation of rna metabolic process GO:0051252 391 0.026
response to growth factor GO:0070848 189 0.026
response to nutrient levels GO:0031667 370 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
regulation of molecular function GO:0065009 398 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
positive regulation of molecular function GO:0044093 230 0.025
cellular component biogenesis GO:0044085 368 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
organelle organization GO:0006996 266 0.025
neurological system process GO:0050877 219 0.025
neuron projection development GO:0031175 273 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
transmembrane transport GO:0055085 412 0.024
aging GO:0007568 241 0.024
negative regulation of cell communication GO:0010648 158 0.024
organic substance catabolic process GO:1901575 316 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
cell projection organization GO:0030030 302 0.024
synaptic transmission GO:0007268 235 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
ion transmembrane transport GO:0034220 365 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
response to extracellular stimulus GO:0009991 380 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
organophosphate metabolic process GO:0019637 370 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.022
cellular component morphogenesis GO:0032989 155 0.022
regulation of transcription dna templated GO:0006355 374 0.022
cellular catabolic process GO:0044248 295 0.022
response to metal ion GO:0010038 253 0.022
nucleotide metabolic process GO:0009117 279 0.022
regulation of protein metabolic process GO:0051246 289 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
cellular response to hormone stimulus GO:0032870 247 0.021
nucleoside metabolic process GO:0009116 179 0.021
positive regulation of developmental process GO:0051094 283 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
regulation of phosphorylation GO:0042325 248 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
cation transport GO:0006812 382 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
intracellular transport GO:0046907 185 0.020
positive regulation of gene expression GO:0010628 244 0.020
programmed cell death GO:0012501 392 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
negative regulation of gene expression GO:0010629 199 0.020
cell projection morphogenesis GO:0048858 123 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
macromolecule localization GO:0033036 252 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
cellular homeostasis GO:0019725 252 0.020
negative regulation of signaling GO:0023057 157 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
regulation of apoptotic process GO:0042981 335 0.020
response to wounding GO:0009611 254 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
multi organism reproductive process GO:0044703 262 0.019
cellular component assembly GO:0022607 360 0.019
response to acid chemical GO:0001101 222 0.019
protein localization GO:0008104 191 0.019
regulation of proteasomal protein catabolic process GO:0061136 4 0.019
regulation of cell projection organization GO:0031344 175 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
reproductive process GO:0022414 372 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
secretion GO:0046903 307 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
regulation of cell development GO:0060284 263 0.018
regulation of system process GO:0044057 208 0.018
alpha amino acid metabolic process GO:1901605 71 0.018
cell morphogenesis GO:0000902 142 0.018
single organism intracellular transport GO:1902582 166 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
apoptotic process GO:0006915 381 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
chemical homeostasis GO:0048878 292 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
regulation of protein modification process GO:0031399 194 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
regulation of neuron differentiation GO:0045664 208 0.018
response to ketone GO:1901654 182 0.018
regulation of nervous system development GO:0051960 264 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
multicellular organism growth GO:0035264 1 0.017
heterocycle catabolic process GO:0046700 167 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
gland development GO:0048732 155 0.017
positive regulation of transport GO:0051050 245 0.017
ras protein signal transduction GO:0007265 29 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
ion homeostasis GO:0050801 212 0.017
regulation of neurogenesis GO:0050767 247 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
head development GO:0060322 247 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.016
response to peptide GO:1901652 292 0.016
organophosphate catabolic process GO:0046434 148 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
response to monosaccharide GO:0034284 159 0.016
rhythmic process GO:0048511 156 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
regulation of neuron projection development GO:0010975 161 0.016
aromatic compound catabolic process GO:0019439 168 0.016
anion transport GO:0006820 178 0.016
cell part morphogenesis GO:0032990 123 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
lipid metabolic process GO:0006629 283 0.015
regulation of cell proliferation GO:0042127 359 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
cellular ion homeostasis GO:0006873 184 0.015
brain development GO:0007420 247 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
metal ion homeostasis GO:0055065 186 0.015
metal ion transport GO:0030001 289 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
protein autophosphorylation GO:0046777 66 0.015
purine containing compound catabolic process GO:0072523 138 0.015
response to corticosteroid GO:0031960 235 0.015
nucleoside catabolic process GO:0009164 126 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
regulation of hormone levels GO:0010817 187 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
protein complex subunit organization GO:0071822 302 0.015
developmental process involved in reproduction GO:0003006 159 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of signaling GO:0023056 270 0.015
cellular response to external stimulus GO:0071496 118 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
defense response GO:0006952 194 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
reproduction GO:0000003 245 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
response to estrogen GO:0043627 232 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
response to decreased oxygen levels GO:0036293 237 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
positive regulation of nervous system development GO:0051962 178 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
cellular cation homeostasis GO:0030003 180 0.014
response to carbohydrate GO:0009743 183 0.014
macromolecular complex assembly GO:0065003 273 0.014
positive regulation of cell development GO:0010720 176 0.014
cellular response to vitamin e GO:0071306 3 0.014
response to hexose GO:0009746 144 0.014
response to glucocorticoid GO:0051384 223 0.013
response to toxic substance GO:0009636 133 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
multicellular organism reproduction GO:0032504 233 0.013
response to radiation GO:0009314 137 0.013
regulation of synaptic transmission GO:0050804 141 0.013
cellular component movement GO:0006928 248 0.013
protein complex biogenesis GO:0070271 263 0.013
cellular chemical homeostasis GO:0055082 247 0.013
vesicle mediated transport GO:0016192 181 0.013
axis specification GO:0009798 4 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
circulatory system process GO:0003013 183 0.013
positive regulation of secretion GO:0051047 140 0.013
protein complex assembly GO:0006461 263 0.013
dna metabolic process GO:0006259 96 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
eye morphogenesis GO:0048592 4 0.013
response to hypoxia GO:0001666 231 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
reproductive structure development GO:0048608 128 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of secretion GO:0051046 224 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
regulation of cellular localization GO:0060341 263 0.013
response to glucose GO:0009749 136 0.013
locomotion GO:0040011 237 0.013
cation transmembrane transport GO:0098655 263 0.013
establishment of protein localization GO:0045184 141 0.013
protein oligomerization GO:0051259 191 0.013
regulation of kinase activity GO:0043549 117 0.013
female pregnancy GO:0007565 122 0.013
oxidation reduction process GO:0055114 304 0.013
circulatory system development GO:0072359 134 0.013
secretion by cell GO:0032940 248 0.012
cellular response to lipid GO:0071396 201 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
single organism reproductive process GO:0044702 297 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
cellular lipid metabolic process GO:0044255 208 0.012
positive regulation of protein modification process GO:0031401 142 0.012
gastrulation GO:0007369 2 0.012
multi multicellular organism process GO:0044706 138 0.012
cation homeostasis GO:0055080 195 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of protein kinase activity GO:0045859 105 0.012
anterior posterior pattern specification GO:0009952 1 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
nucleotide catabolic process GO:0009166 139 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
behavior GO:0007610 205 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
negative regulation of cell death GO:0060548 229 0.012
response to nutrient GO:0007584 248 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of transferase activity GO:0051338 123 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
growth GO:0040007 165 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
small molecule biosynthetic process GO:0044283 124 0.012
reproductive system development GO:0061458 128 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
negative regulation of molecular function GO:0044092 133 0.012
mapk cascade GO:0000165 140 0.012
positive regulation of cell communication GO:0010647 271 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
cardiovascular system development GO:0072358 134 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of mapk cascade GO:0043408 116 0.012
heart morphogenesis GO:0003007 3 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
tissue development GO:0009888 252 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
cellular response to peptide GO:1901653 133 0.012
peptidyl amino acid modification GO:0018193 126 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
positive regulation of cell death GO:0010942 184 0.011
response to vitamin GO:0033273 131 0.011
muscle system process GO:0003012 115 0.011
regulation of secretion by cell GO:1903530 208 0.011
lipid biosynthetic process GO:0008610 128 0.011
neuron death GO:0070997 127 0.011
peptide transport GO:0015833 97 0.011
response to peptide hormone GO:0043434 278 0.011
embryonic pattern specification GO:0009880 1 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
single organism organelle organization GO:1902589 180 0.011
regulation of membrane potential GO:0042391 110 0.011
circadian rhythm GO:0007623 88 0.011
immune system process GO:0002376 204 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of response to stress GO:0080134 126 0.011
response to alkaloid GO:0043279 132 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
blood circulation GO:0008015 183 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
sex differentiation GO:0007548 113 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
cellular macromolecule localization GO:0070727 122 0.010
response to cytokine GO:0034097 215 0.010
axon development GO:0061564 96 0.010
response to purine containing compound GO:0014074 126 0.010
protein localization to organelle GO:0033365 57 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
mesoderm development GO:0007498 2 0.010
negative regulation of transport GO:0051051 136 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of catabolic process GO:0009894 113 0.010
glial cell differentiation GO:0010001 65 0.010
cytoplasmic transport GO:0016482 115 0.010
single organism behavior GO:0044708 130 0.010
regulation of neuron death GO:1901214 115 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
gliogenesis GO:0042063 93 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010

Cldn12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.012
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.011
cardiovascular system disease DOID:1287 0 0.011
cancer DOID:162 0 0.011
sensory system disease DOID:0050155 0 0.010
organ system cancer DOID:0050686 0 0.010