Rattus norvegicus

0 known processes

Cldn15

claudin 15

Cldn15 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.077
oxoacid metabolic process GO:0043436 290 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.068
cellular response to oxygen containing compound GO:1901701 386 0.068
cation homeostasis GO:0055080 195 0.064
regulation of neurogenesis GO:0050767 247 0.062
organic acid metabolic process GO:0006082 292 0.061
programmed cell death GO:0012501 392 0.061
rna biosynthetic process GO:0032774 380 0.060
anatomical structure morphogenesis GO:0009653 298 0.059
negative regulation of macromolecule metabolic process GO:0010605 260 0.058
carboxylic acid metabolic process GO:0019752 289 0.056
transcription from rna polymerase ii promoter GO:0006366 252 0.054
regulation of rna biosynthetic process GO:2001141 381 0.053
homeostatic process GO:0042592 331 0.051
single organism reproductive process GO:0044702 297 0.051
positive regulation of multicellular organismal process GO:0051240 387 0.050
apoptotic process GO:0006915 381 0.049
regulation of cell differentiation GO:0045595 320 0.049
response to inorganic substance GO:0010035 377 0.049
neurological system process GO:0050877 219 0.049
reproductive process GO:0022414 372 0.049
Rat
transcription dna templated GO:0006351 377 0.048
nucleic acid templated transcription GO:0097659 379 0.048
rna metabolic process GO:0016070 406 0.048
carbohydrate derivative metabolic process GO:1901135 346 0.048
chemical homeostasis GO:0048878 292 0.047
response to acid chemical GO:0001101 222 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.045
neuron differentiation GO:0030182 368 0.043
tissue development GO:0009888 252 0.042
regulation of molecular function GO:0065009 398 0.042
response to extracellular stimulus GO:0009991 380 0.042
regulation of rna metabolic process GO:0051252 391 0.041
cellular amino acid metabolic process GO:0006520 107 0.041
cellular response to stress GO:0033554 269 0.040
cellular amine metabolic process GO:0044106 38 0.040
regulation of multicellular organismal development GO:2000026 376 0.039
regulation of apoptotic process GO:0042981 335 0.039
cellular response to endogenous stimulus GO:0071495 377 0.039
regulation of neuron differentiation GO:0045664 208 0.038
transmembrane transport GO:0055085 412 0.038
locomotion GO:0040011 237 0.037
response to ketone GO:1901654 182 0.037
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
regulation of protein metabolic process GO:0051246 289 0.036
positive regulation of transcription dna templated GO:0045893 197 0.035
response to peptide GO:1901652 292 0.035
macromolecular complex assembly GO:0065003 273 0.035
single organism catabolic process GO:0044712 283 0.035
amine metabolic process GO:0009308 38 0.035
positive regulation of gene expression GO:0010628 244 0.034
regulation of cellular localization GO:0060341 263 0.034
regulation of signal transduction GO:0009966 318 0.034
regulation of programmed cell death GO:0043067 341 0.034
regulation of hormone levels GO:0010817 187 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
regulation of cell proliferation GO:0042127 359 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
regulation of cell development GO:0060284 263 0.033
organic substance catabolic process GO:1901575 316 0.033
positive regulation of catalytic activity GO:0043085 184 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
intracellular signal transduction GO:0035556 314 0.031
regulation of cellular component organization GO:0051128 368 0.031
cellular homeostasis GO:0019725 252 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
ribose phosphate metabolic process GO:0019693 235 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
neuron projection development GO:0031175 273 0.031
cellular cation homeostasis GO:0030003 180 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
cellular component biogenesis GO:0044085 368 0.031
response to oxygen levels GO:0070482 265 0.030
development of primary sexual characteristics GO:0045137 107 0.030
protein localization GO:0008104 191 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
reproductive structure development GO:0048608 128 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
cellular catabolic process GO:0044248 295 0.029
response to nutrient levels GO:0031667 370 0.029
response to peptide hormone GO:0043434 278 0.028
head development GO:0060322 247 0.028
epithelium development GO:0060429 96 0.028
regulation of transcription dna templated GO:0006355 374 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
positive regulation of transport GO:0051050 245 0.028
cellular chemical homeostasis GO:0055082 247 0.028
negative regulation of metabolic process GO:0009892 331 0.028
secretion GO:0046903 307 0.028
cell projection organization GO:0030030 302 0.027
ion transmembrane transport GO:0034220 365 0.027
regulation of nervous system development GO:0051960 264 0.027
regulation of secretion GO:0051046 224 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
neuron development GO:0048666 286 0.027
ion homeostasis GO:0050801 212 0.026
brain development GO:0007420 247 0.026
central nervous system development GO:0007417 311 0.026
catabolic process GO:0009056 351 0.026
hormone transport GO:0009914 121 0.026
developmental process involved in reproduction GO:0003006 159 0.026
response to nutrient GO:0007584 248 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
cellular response to lipid GO:0071396 201 0.026
cellular component assembly GO:0022607 360 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
nitrogen compound transport GO:0071705 229 0.025
regulation of catalytic activity GO:0050790 304 0.025
sensory perception GO:0007600 101 0.025
positive regulation of molecular function GO:0044093 230 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
protein phosphorylation GO:0006468 345 0.024
response to radiation GO:0009314 137 0.024
immune system process GO:0002376 204 0.024
cellular ketone metabolic process GO:0042180 51 0.024
eye morphogenesis GO:0048592 4 0.023
multi organism reproductive process GO:0044703 262 0.023
Rat
negative regulation of cell communication GO:0010648 158 0.023
protein complex biogenesis GO:0070271 263 0.023
reproduction GO:0000003 245 0.023
limb morphogenesis GO:0035108 4 0.023
protein oligomerization GO:0051259 191 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
metal ion homeostasis GO:0055065 186 0.022
nucleotide metabolic process GO:0009117 279 0.022
ras protein signal transduction GO:0007265 29 0.022
response to growth factor GO:0070848 189 0.021
signal release GO:0023061 145 0.021
cation transport GO:0006812 382 0.021
macromolecule localization GO:0033036 252 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
reproductive system development GO:0061458 128 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
regulation of protein modification process GO:0031399 194 0.021
purine containing compound catabolic process GO:0072523 138 0.021
organelle organization GO:0006996 266 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
organophosphate metabolic process GO:0019637 370 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.021
cellular macromolecule localization GO:0070727 122 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
protein complex subunit organization GO:0071822 302 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
sex differentiation GO:0007548 113 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
amide transport GO:0042886 105 0.020
response to decreased oxygen levels GO:0036293 237 0.020
response to alkaloid GO:0043279 132 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
axis specification GO:0009798 4 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
purine containing compound metabolic process GO:0072521 253 0.020
negative regulation of gene expression GO:0010629 199 0.020
response to external biotic stimulus GO:0043207 221 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
negative regulation of developmental process GO:0051093 125 0.019
positive regulation of developmental process GO:0051094 283 0.019
regulation of system process GO:0044057 208 0.019
response to glucocorticoid GO:0051384 223 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
membrane organization GO:0061024 94 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of canonical wnt signaling pathway GO:0060828 4 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
proteolysis GO:0006508 175 0.018
response to ethanol GO:0045471 162 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
gonad development GO:0008406 104 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
single organism intracellular transport GO:1902582 166 0.018
positive regulation of secretion GO:0051047 140 0.018
regulation of phosphorylation GO:0042325 248 0.018
aromatic compound catabolic process GO:0019439 168 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
regulation of neuron projection development GO:0010975 161 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
blood circulation GO:0008015 183 0.018
positive regulation of neurogenesis GO:0050769 165 0.017
anion transport GO:0006820 178 0.017
response to carbohydrate GO:0009743 183 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
single organism cellular localization GO:1902580 102 0.017
positive regulation of cell death GO:0010942 184 0.017
single organism organelle organization GO:1902589 180 0.017
single organism biosynthetic process GO:0044711 342 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
regulation of peptide transport GO:0090087 87 0.017
nucleoside metabolic process GO:0009116 179 0.017
regulation of growth GO:0040008 105 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
positive regulation of signal transduction GO:0009967 175 0.017
circulatory system process GO:0003013 183 0.017
embryonic skeletal system development GO:0048706 3 0.017
cell type specific apoptotic process GO:0097285 134 0.017
cellular calcium ion homeostasis GO:0006874 160 0.016
hormone secretion GO:0046879 115 0.016
regulation of anatomical structure size GO:0090066 135 0.016
positive regulation of nervous system development GO:0051962 178 0.016
immune response GO:0006955 104 0.016
regulation of secretion by cell GO:1903530 208 0.016
cellular response to acid chemical GO:0071229 75 0.016
cellular protein localization GO:0034613 122 0.016
chromosome segregation GO:0007059 2 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
lipid metabolic process GO:0006629 283 0.016
response to estrogen GO:0043627 232 0.016
dendrite development GO:0016358 72 0.016
response to oxidative stress GO:0006979 186 0.016
response to cytokine GO:0034097 215 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
response to hypoxia GO:0001666 231 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
peptide transport GO:0015833 97 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cellular component movement GO:0006928 248 0.015
cellular response to external stimulus GO:0071496 118 0.015
regulation of membrane potential GO:0042391 110 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
calcium ion homeostasis GO:0055074 162 0.015
response to mechanical stimulus GO:0009612 134 0.015
cell cell signaling GO:0007267 335 0.015
developmental growth GO:0048589 100 0.015
organic anion transport GO:0015711 132 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
nucleotide catabolic process GO:0009166 139 0.015
cellular ion homeostasis GO:0006873 184 0.015
cell morphogenesis GO:0000902 142 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
retina morphogenesis in camera type eye GO:0060042 1 0.015
protein transport GO:0015031 132 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
response to amino acid GO:0043200 75 0.014
tube formation GO:0035148 3 0.014
establishment of protein localization GO:0045184 141 0.014
protein complex assembly GO:0006461 263 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
cellular response to peptide GO:1901653 133 0.014
growth GO:0040007 165 0.014
sensory organ development GO:0007423 74 0.014
multicellular organism reproduction GO:0032504 233 0.014
multi multicellular organism process GO:0044706 138 0.014
Rat
divalent inorganic cation transport GO:0072511 134 0.014
organophosphate catabolic process GO:0046434 148 0.014
cytoplasmic transport GO:0016482 115 0.014
sexual reproduction GO:0019953 148 0.014
intracellular transport GO:0046907 185 0.014
oxidation reduction process GO:0055114 304 0.014
response to ionizing radiation GO:0010212 59 0.014
negative regulation of cell development GO:0010721 82 0.014
regulation of protein transport GO:0051223 68 0.014
localization of cell GO:0051674 202 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
negative regulation of cell differentiation GO:0045596 99 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
actin filament based process GO:0030029 86 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
calcium ion transport GO:0006816 131 0.013
regulation of hormone secretion GO:0046883 106 0.013
organ morphogenesis GO:0009887 75 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
cell motility GO:0048870 202 0.013
cell cycle GO:0007049 101 0.013
peptide hormone secretion GO:0030072 84 0.013
regulation of ion transport GO:0043269 245 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
regulation of cellular response to stress GO:0080135 49 0.013
peptidyl amino acid modification GO:0018193 126 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
synaptic transmission GO:0007268 235 0.013
secretion by cell GO:0032940 248 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
anterior posterior pattern specification GO:0009952 1 0.012
gland development GO:0048732 155 0.012
response to wounding GO:0009611 254 0.012
cell cycle checkpoint GO:0000075 2 0.012
aging GO:0007568 241 0.012
regulation of protein localization GO:0032880 81 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of catabolic process GO:0009894 113 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
rhythmic process GO:0048511 156 0.012
Rat
positive regulation of signaling GO:0023056 270 0.012
heterocycle catabolic process GO:0046700 167 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
regulation of peptide secretion GO:0002791 82 0.012
single organism membrane organization GO:0044802 74 0.012
negative regulation of cell death GO:0060548 229 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
regulation of cell projection organization GO:0031344 175 0.011
male sex differentiation GO:0046661 64 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
positive regulation of protein modification process GO:0031401 142 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of response to external stimulus GO:0032101 106 0.011
regulation of transferase activity GO:0051338 123 0.011
negative regulation of transport GO:0051051 136 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
regulation of blood pressure GO:0008217 83 0.011
response to monosaccharide GO:0034284 159 0.011
response to other organism GO:0051707 220 0.011
cellular response to oxygen levels GO:0071453 60 0.011
mitotic sister chromatid segregation GO:0000070 1 0.011
appendage morphogenesis GO:0035107 4 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of proteolysis GO:0030162 66 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
regulation of protein kinase activity GO:0045859 105 0.011
response to hexose GO:0009746 144 0.011
regulation of dna metabolic process GO:0051052 60 0.011
cellular component morphogenesis GO:0032989 155 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of organelle organization GO:0033043 80 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
cellular lipid metabolic process GO:0044255 208 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
regulation of fat cell differentiation GO:0045598 3 0.010
circadian rhythm GO:0007623 88 0.010
Rat
action potential GO:0001508 54 0.010
gamete generation GO:0007276 124 0.010
negative regulation of molecular function GO:0044092 133 0.010
heart development GO:0007507 72 0.010
spermatogenesis GO:0007283 99 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
defense response GO:0006952 194 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
male gamete generation GO:0048232 99 0.010
response to corticosteroid GO:0031960 235 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
regulation of dendrite development GO:0050773 59 0.010

Cldn15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010
sensory system disease DOID:0050155 0 0.010