Rattus norvegicus

133 known processes

Mbd2

methyl-CpG binding domain protein 2

(Aliases: MGC188552)

Mbd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.119
cellular amino acid metabolic process GO:0006520 107 0.106
regulation of signal transduction GO:0009966 318 0.102
regulation of protein modification process GO:0031399 194 0.081
programmed cell death GO:0012501 392 0.080
enzyme linked receptor protein signaling pathway GO:0007167 116 0.079
carboxylic acid metabolic process GO:0019752 289 0.078
protein phosphorylation GO:0006468 345 0.077
cellular response to endogenous stimulus GO:0071495 377 0.075
neuron projection development GO:0031175 273 0.070
regulation of nucleic acid templated transcription GO:1903506 380 0.068
negative regulation of macromolecule metabolic process GO:0010605 260 0.067
oxoacid metabolic process GO:0043436 290 0.065
negative regulation of biosynthetic process GO:0009890 168 0.061
regulation of protein phosphorylation GO:0001932 183 0.060
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.059
rna metabolic process GO:0016070 406 0.059
organic acid metabolic process GO:0006082 292 0.059
negative regulation of rna biosynthetic process GO:1902679 118 0.056
negative regulation of metabolic process GO:0009892 331 0.056
cellular response to insulin stimulus GO:0032869 81 0.055
regulation of phosphorus metabolic process GO:0051174 349 0.055
cellular response to cytokine stimulus GO:0071345 127 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.054
regulation of rna biosynthetic process GO:2001141 381 0.054
negative regulation of cellular metabolic process GO:0031324 281 0.054
cellular response to oxygen containing compound GO:1901701 386 0.054
regulation of molecular function GO:0065009 398 0.052
regulation of phosphorylation GO:0042325 248 0.052
intracellular signal transduction GO:0035556 314 0.052
regulation of multicellular organismal development GO:2000026 376 0.051
regulation of apoptotic process GO:0042981 335 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.050
circulatory system development GO:0072359 134 0.049
central nervous system development GO:0007417 311 0.048
negative regulation of nucleic acid templated transcription GO:1903507 117 0.048
transcription from rna polymerase ii promoter GO:0006366 252 0.048
regulation of transcription dna templated GO:0006355 374 0.046
regulation of cellular localization GO:0060341 263 0.046
regulation of cellular protein metabolic process GO:0032268 267 0.045
regulation of cellular amine metabolic process GO:0033238 8 0.045
regulation of cellular component organization GO:0051128 368 0.044
regulation of cellular ketone metabolic process GO:0010565 27 0.043
apoptotic process GO:0006915 381 0.043
cardiovascular system development GO:0072358 134 0.042
cellular ketone metabolic process GO:0042180 51 0.040
positive regulation of biosynthetic process GO:0009891 319 0.039
defense response GO:0006952 194 0.039
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
negative regulation of signaling GO:0023057 157 0.038
positive regulation of phosphorylation GO:0042327 177 0.038
response to cytokine GO:0034097 215 0.038
regulation of intracellular signal transduction GO:1902531 218 0.037
locomotion GO:0040011 237 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.036
nucleic acid templated transcription GO:0097659 379 0.036
regulation of mapk cascade GO:0043408 116 0.036
cellular component biogenesis GO:0044085 368 0.036
regulation of protein metabolic process GO:0051246 289 0.035
positive regulation of developmental process GO:0051094 283 0.035
regulation of cell differentiation GO:0045595 320 0.035
organic substance catabolic process GO:1901575 316 0.035
endocytosis GO:0006897 84 0.035
response to other organism GO:0051707 220 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.034
cell projection organization GO:0030030 302 0.034
cellular catabolic process GO:0044248 295 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
negative regulation of protein metabolic process GO:0051248 114 0.033
mesoderm development GO:0007498 2 0.033
small gtpase mediated signal transduction GO:0007264 36 0.033
cellular component morphogenesis GO:0032989 155 0.032
ras protein signal transduction GO:0007265 29 0.032
regulation of cell proliferation GO:0042127 359 0.032
cellular response to peptide hormone stimulus GO:0071375 120 0.031
transcription dna templated GO:0006351 377 0.031
cytoplasmic transport GO:0016482 115 0.031
amine metabolic process GO:0009308 38 0.031
negative regulation of transport GO:0051051 136 0.031
negative regulation of cellular protein metabolic process GO:0032269 106 0.031
regulation of cell projection organization GO:0031344 175 0.031
rna biosynthetic process GO:0032774 380 0.030
single organism catabolic process GO:0044712 283 0.030
brain development GO:0007420 247 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
positive regulation of cell communication GO:0010647 271 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
neuron development GO:0048666 286 0.029
response to nutrient levels GO:0031667 370 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
immune system process GO:0002376 204 0.029
intracellular transport GO:0046907 185 0.029
neuron differentiation GO:0030182 368 0.028
negative regulation of response to stimulus GO:0048585 155 0.028
homeostatic process GO:0042592 331 0.028
regulation of rna metabolic process GO:0051252 391 0.028
positive regulation of transport GO:0051050 245 0.028
regulation of catabolic process GO:0009894 113 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
nucleotide metabolic process GO:0009117 279 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
regulation of neurogenesis GO:0050767 247 0.027
regulation of vesicle mediated transport GO:0060627 81 0.027
regulation of nervous system development GO:0051960 264 0.027
positive regulation of protein modification process GO:0031401 142 0.027
transmembrane transport GO:0055085 412 0.027
response to extracellular stimulus GO:0009991 380 0.027
negative regulation of rna metabolic process GO:0051253 123 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
response to peptide GO:1901652 292 0.026
regulation of programmed cell death GO:0043067 341 0.026
cellular response to peptide GO:1901653 133 0.026
cellular response to stress GO:0033554 269 0.026
metaphase anaphase transition of cell cycle GO:0044784 1 0.025
neurological system process GO:0050877 219 0.025
peptidyl tyrosine modification GO:0018212 72 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
catabolic process GO:0009056 351 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
ribonucleotide metabolic process GO:0009259 231 0.024
positive regulation of signaling GO:0023056 270 0.024
response to insulin GO:0032868 133 0.024
regulation of cell development GO:0060284 263 0.024
negative regulation of cell communication GO:0010648 158 0.024
proteolysis GO:0006508 175 0.024
cellular amine metabolic process GO:0044106 38 0.024
vasculature development GO:0001944 70 0.024
embryonic pattern specification GO:0009880 1 0.024
multi organism reproductive process GO:0044703 262 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
regulation of response to stress GO:0080134 126 0.023
organophosphate metabolic process GO:0019637 370 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.023
lipid transport GO:0006869 61 0.023
biological adhesion GO:0022610 110 0.023
cellular protein localization GO:0034613 122 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
taxis GO:0042330 67 0.022
single organism intracellular transport GO:1902582 166 0.022
dephosphorylation GO:0016311 98 0.022
response to estrogen GO:0043627 232 0.022
reproductive process GO:0022414 372 0.022
nitrogen compound transport GO:0071705 229 0.021
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.021
cell cell signaling GO:0007267 335 0.021
chemical homeostasis GO:0048878 292 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
cellular component movement GO:0006928 248 0.021
regulation of protein kinase activity GO:0045859 105 0.021
cell migration GO:0016477 197 0.021
response to external biotic stimulus GO:0043207 221 0.021
response to wounding GO:0009611 254 0.021
positive regulation of immune system process GO:0002684 90 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
cell growth GO:0016049 104 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
negative regulation of gene expression GO:0010629 199 0.020
aromatic compound catabolic process GO:0019439 168 0.020
regulation of chromosome segregation GO:0051983 1 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
macromolecule localization GO:0033036 252 0.020
localization of cell GO:0051674 202 0.020
heart development GO:0007507 72 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
reproduction GO:0000003 245 0.019
lipid metabolic process GO:0006629 283 0.019
response to biotic stimulus GO:0009607 226 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
positive regulation of cell development GO:0010720 176 0.019
regulation of kinase activity GO:0043549 117 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
mapk cascade GO:0000165 140 0.019
head development GO:0060322 247 0.019
cellular component assembly GO:0022607 360 0.018
cellular lipid metabolic process GO:0044255 208 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
regulation of mitotic sister chromatid separation GO:0010965 1 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of catalytic activity GO:0050790 304 0.018
anterior posterior pattern specification GO:0009952 1 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
cell cycle checkpoint GO:0000075 2 0.018
regulation of transferase activity GO:0051338 123 0.018
growth GO:0040007 165 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
synaptic transmission GO:0007268 235 0.017
establishment of protein localization GO:0045184 141 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
response to nutrient GO:0007584 248 0.017
rhythmic process GO:0048511 156 0.017
cell projection morphogenesis GO:0048858 123 0.017
response to peptide hormone GO:0043434 278 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of developmental process GO:0051093 125 0.017
angiogenesis GO:0001525 53 0.017
protein complex subunit organization GO:0071822 302 0.017
cation transport GO:0006812 382 0.017
single organism reproductive process GO:0044702 297 0.016
nuclear transport GO:0051169 49 0.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.016
peptidyl amino acid modification GO:0018193 126 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.016
ubiquitin dependent protein catabolic process GO:0006511 14 0.016
axis specification GO:0009798 4 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
anion transport GO:0006820 178 0.016
regulation of neuron projection development GO:0010975 161 0.016
modification dependent macromolecule catabolic process GO:0043632 14 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
single organism biosynthetic process GO:0044711 342 0.016
mitotic sister chromatid segregation GO:0000070 1 0.016
carbohydrate metabolic process GO:0005975 130 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
oxidation reduction process GO:0055114 304 0.015
regulation of sister chromatid segregation GO:0033045 1 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
salivary gland development GO:0007431 3 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
positive regulation of cell death GO:0010942 184 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
positive regulation of nervous system development GO:0051962 178 0.015
metal ion transport GO:0030001 289 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
mitotic sister chromatid separation GO:0051306 1 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
protein autophosphorylation GO:0046777 66 0.015
secretion by cell GO:0032940 248 0.015
organelle localization GO:0051640 55 0.014
single organism cellular localization GO:1902580 102 0.014
multicellular organism reproduction GO:0032504 233 0.014
cellular chemical homeostasis GO:0055082 247 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
negative regulation of signal transduction GO:0009968 83 0.014
tissue development GO:0009888 252 0.014
aging GO:0007568 241 0.014
positive regulation of gene expression GO:0010628 244 0.014
purine containing compound metabolic process GO:0072521 253 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
cation transmembrane transport GO:0098655 263 0.014
lipid biosynthetic process GO:0008610 128 0.014
response to lipopolysaccharide GO:0032496 191 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
cellular macromolecule localization GO:0070727 122 0.014
regulation of mitotic sister chromatid segregation GO:0033047 1 0.014
ion transmembrane transport GO:0034220 365 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
establishment of organelle localization GO:0051656 37 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
blood vessel development GO:0001568 69 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
regulation of neuron differentiation GO:0045664 208 0.013
phosphatidylinositol dephosphorylation GO:0046856 4 0.013
cell part morphogenesis GO:0032990 123 0.013
positive regulation of kinase activity GO:0033674 77 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.013
protein localization GO:0008104 191 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
glucose homeostasis GO:0042593 75 0.013
chemotaxis GO:0006935 66 0.013
regulation of ion transport GO:0043269 245 0.013
b cell differentiation GO:0030183 2 0.013
regulation of locomotion GO:0040012 148 0.013
lipid localization GO:0010876 62 0.013
maintenance of location GO:0051235 17 0.013
muscle structure development GO:0061061 87 0.013
regulation of neuron death GO:1901214 115 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of transmembrane transport GO:0034762 122 0.013
neuron projection morphogenesis GO:0048812 122 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
blood vessel morphogenesis GO:0048514 58 0.013
positive regulation of catalytic activity GO:0043085 184 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
cell morphogenesis GO:0000902 142 0.012
behavior GO:0007610 205 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of molecular function GO:0044093 230 0.012
negative regulation of protein modification process GO:0031400 52 0.012
peptide secretion GO:0002790 86 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
cell adhesion GO:0007155 110 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
cellular macromolecule catabolic process GO:0044265 29 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
regulation of cell cycle GO:0051726 73 0.012
protein heterooligomerization GO:0051291 89 0.012
cell motility GO:0048870 202 0.012
circulatory system process GO:0003013 183 0.012
response to estradiol GO:0032355 164 0.012
protein maturation GO:0051604 68 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
macromolecule catabolic process GO:0009057 58 0.012
protein import into nucleus GO:0006606 35 0.012
regulation of protein maturation GO:1903317 50 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
embryonic axis specification GO:0000578 1 0.012
regulation of vasculature development GO:1901342 44 0.012
developmental process involved in reproduction GO:0003006 159 0.012
adult locomotory behavior GO:0008344 4 0.011
regulation of endocytosis GO:0030100 42 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of hormone levels GO:0010817 187 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of intracellular transport GO:0032386 65 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
ion homeostasis GO:0050801 212 0.011
protein transport GO:0015031 132 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
response to glucose GO:0009749 136 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of immune system process GO:0002682 123 0.011
cellular homeostasis GO:0019725 252 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
rna localization GO:0006403 4 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
carbohydrate homeostasis GO:0033500 75 0.011
positive regulation of transferase activity GO:0051347 81 0.011
negative regulation of secretion GO:0051048 82 0.010
regulation of embryonic development GO:0045995 2 0.010
rho protein signal transduction GO:0007266 11 0.010
erbb signaling pathway GO:0038127 23 0.010
organelle organization GO:0006996 266 0.010
regulation of cell adhesion GO:0030155 52 0.010
single organism membrane organization GO:0044802 74 0.010
protein complex biogenesis GO:0070271 263 0.010
regulation of transporter activity GO:0032409 50 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
negative regulation of protein maturation GO:1903318 47 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
gtp metabolic process GO:0046039 72 0.010
muscle cell proliferation GO:0033002 84 0.010
positive regulation of signal transduction GO:0009967 175 0.010
divalent inorganic cation transport GO:0072511 134 0.010
amide transport GO:0042886 105 0.010
establishment of tissue polarity GO:0007164 2 0.010
protein dephosphorylation GO:0006470 38 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
response to growth factor GO:0070848 189 0.010
intracellular protein transport GO:0006886 79 0.010
divalent metal ion transport GO:0070838 132 0.010
gastrulation GO:0007369 2 0.010
carboxylic acid transport GO:0046942 115 0.010

Mbd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
central nervous system disease DOID:331 0 0.010
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010