Rattus norvegicus

0 known processes

Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

(Aliases: MGC95068)

Arhgef2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate metabolic process GO:0019637 370 0.059
Human Mouse
regulation of molecular function GO:0065009 398 0.054
Human Mouse Rat
negative regulation of metabolic process GO:0009892 331 0.050
organic substance catabolic process GO:1901575 316 0.040
Human Mouse
intracellular signal transduction GO:0035556 314 0.040
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.040
Human
cellular component biogenesis GO:0044085 368 0.038
regulation of programmed cell death GO:0043067 341 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
Human Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
Human Mouse
response to oxygen levels GO:0070482 265 0.035
cellular component assembly GO:0022607 360 0.035
rna biosynthetic process GO:0032774 380 0.035
Human
positive regulation of gene expression GO:0010628 244 0.034
Human
chemical homeostasis GO:0048878 292 0.034
response to peptide GO:1901652 292 0.033
Human
regulation of signal transduction GO:0009966 318 0.033
Human Mouse
regulation of transcription dna templated GO:0006355 374 0.033
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
Human
homeostatic process GO:0042592 331 0.032
regulation of catalytic activity GO:0050790 304 0.031
Human Mouse Rat
cellular ketone metabolic process GO:0042180 51 0.031
apoptotic process GO:0006915 381 0.031
nucleic acid templated transcription GO:0097659 379 0.031
Human
macromolecular complex subunit organization GO:0043933 339 0.030
Human Mouse
positive regulation of cell death GO:0010942 184 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
Human
regulation of apoptotic process GO:0042981 335 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
programmed cell death GO:0012501 392 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
Human
neuron differentiation GO:0030182 368 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
Human
response to acid chemical GO:0001101 222 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
Human Mouse
positive regulation of rna metabolic process GO:0051254 203 0.027
Human
protein complex subunit organization GO:0071822 302 0.027
Human Mouse
regulation of cellular component organization GO:0051128 368 0.027
Human
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
amine metabolic process GO:0009308 38 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
Human
cellular response to oxygen containing compound GO:1901701 386 0.026
Human
transcription dna templated GO:0006351 377 0.025
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
protein complex assembly GO:0006461 263 0.025
transmembrane transport GO:0055085 412 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
Human
positive regulation of cellular component organization GO:0051130 200 0.025
locomotion GO:0040011 237 0.025
response to decreased oxygen levels GO:0036293 237 0.025
regulation of protein metabolic process GO:0051246 289 0.025
Human Rat
positive regulation of response to stimulus GO:0048584 285 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
organic acid metabolic process GO:0006082 292 0.024
central nervous system development GO:0007417 311 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
protein localization GO:0008104 191 0.024
regulation of rna biosynthetic process GO:2001141 381 0.023
Human
positive regulation of transcription dna templated GO:0045893 197 0.023
Human
positive regulation of apoptotic process GO:0043065 154 0.023
single organism biosynthetic process GO:0044711 342 0.023
regulation of vesicle mediated transport GO:0060627 81 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
Human Rat
cation transport GO:0006812 382 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.022
Human Mouse
regulation of cell projection organization GO:0031344 175 0.022
lipid metabolic process GO:0006629 283 0.022
macromolecular complex assembly GO:0065003 273 0.022
cellular component movement GO:0006928 248 0.022
reproductive process GO:0022414 372 0.022
nucleotide metabolic process GO:0009117 279 0.022
Human Mouse
negative regulation of gene expression GO:0010629 199 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
Human Mouse
positive regulation of molecular function GO:0044093 230 0.022
Human Mouse
protein phosphorylation GO:0006468 345 0.021
Human Rat
regulation of cell differentiation GO:0045595 320 0.021
Mouse
negative regulation of response to stimulus GO:0048585 155 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
ion transmembrane transport GO:0034220 365 0.021
neuron development GO:0048666 286 0.021
secretion by cell GO:0032940 248 0.021
response to inorganic substance GO:0010035 377 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
Human Mouse
nucleoside metabolic process GO:0009116 179 0.020
Human Mouse
regulation of cellular localization GO:0060341 263 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
purine containing compound metabolic process GO:0072521 253 0.020
Human Mouse
organelle organization GO:0006996 266 0.020
Human Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.020
Human
cellular amine metabolic process GO:0044106 38 0.020
cellular catabolic process GO:0044248 295 0.020
Human Mouse
oxoacid metabolic process GO:0043436 290 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
Human Mouse
cellular response to hormone stimulus GO:0032870 247 0.020
cellular homeostasis GO:0019725 252 0.020
positive regulation of developmental process GO:0051094 283 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
Human Mouse
organic cyclic compound catabolic process GO:1901361 175 0.019
Human Mouse
positive regulation of transport GO:0051050 245 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
Human
ras protein signal transduction GO:0007265 29 0.019
Mouse
response to hypoxia GO:0001666 231 0.019
cellular chemical homeostasis GO:0055082 247 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.018
Human Mouse Rat
regulation of hydrolase activity GO:0051336 143 0.018
Human Mouse
positive regulation of cell communication GO:0010647 271 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
Human Mouse
regulation of secretion by cell GO:1903530 208 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
chromosome segregation GO:0007059 2 0.018
brain development GO:0007420 247 0.018
aging GO:0007568 241 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
Mouse
organophosphate catabolic process GO:0046434 148 0.018
Human Mouse
actin filament based process GO:0030029 86 0.018
Human Mouse
carbohydrate derivative catabolic process GO:1901136 147 0.017
Human Mouse
regulation of cellular catabolic process GO:0031329 101 0.017
Human Mouse
regulation of rna metabolic process GO:0051252 391 0.017
Human
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
Human Mouse
positive regulation of programmed cell death GO:0043068 157 0.017
cell projection organization GO:0030030 302 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
Mouse
secretion GO:0046903 307 0.017
eye morphogenesis GO:0048592 4 0.017
negative regulation of biosynthetic process GO:0009890 168 0.016
response to extracellular stimulus GO:0009991 380 0.016
protein oligomerization GO:0051259 191 0.016
cellular response to stress GO:0033554 269 0.016
cellular lipid metabolic process GO:0044255 208 0.016
aromatic compound catabolic process GO:0019439 168 0.016
Human Mouse
positive regulation of cell proliferation GO:0008284 249 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
Human
purine ribonucleotide metabolic process GO:0009150 227 0.016
Human Mouse
catabolic process GO:0009056 351 0.016
Human Mouse
head development GO:0060322 247 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
Human Mouse
purine containing compound catabolic process GO:0072523 138 0.016
Human Mouse
positive regulation of cell differentiation GO:0045597 217 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
mitotic spindle organization GO:0007052 2 0.016
tissue development GO:0009888 252 0.016
neuron projection development GO:0031175 273 0.016
metal ion transport GO:0030001 289 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
Human Mouse
negative regulation of cell death GO:0060548 229 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
regulation of membrane potential GO:0042391 110 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
Human Mouse
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
Human Mouse
proteolysis GO:0006508 175 0.015
response to oxidative stress GO:0006979 186 0.015
rna metabolic process GO:0016070 406 0.015
Human
cation homeostasis GO:0055080 195 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
Human Mouse
single organism organelle organization GO:1902589 180 0.015
Human Mouse
growth GO:0040007 165 0.015
ion homeostasis GO:0050801 212 0.015
spindle organization GO:0007051 2 0.015
multi organism reproductive process GO:0044703 262 0.014
negative regulation of cell communication GO:0010648 158 0.014
heterocycle catabolic process GO:0046700 167 0.014
Human Mouse
developmental growth GO:0048589 100 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
Human Mouse
multicellular organism growth GO:0035264 1 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
Human Mouse
negative regulation of signaling GO:0023057 157 0.014
macromolecule localization GO:0033036 252 0.014
regulation of nervous system development GO:0051960 264 0.014
Mouse
regulation of phosphorylation GO:0042325 248 0.014
Human Rat
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
protein complex biogenesis GO:0070271 263 0.014
regulation of protein modification process GO:0031399 194 0.014
Human Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.014
Human
monovalent inorganic cation transport GO:0015672 172 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
Human
regulation of growth GO:0040008 105 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
Human Mouse
regulation of transferase activity GO:0051338 123 0.013
Rat
reproduction GO:0000003 245 0.013
carbohydrate metabolic process GO:0005975 130 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
Human Mouse
positive regulation of nervous system development GO:0051962 178 0.013
neuron death GO:0070997 127 0.013
neuromuscular process GO:0050905 2 0.013
cell type specific apoptotic process GO:0097285 134 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
Human Mouse
positive regulation of signaling GO:0023056 270 0.013
cell morphogenesis GO:0000902 142 0.013
Human Mouse
response to wounding GO:0009611 254 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
negative regulation of molecular function GO:0044092 133 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
Human Mouse
vesicle mediated transport GO:0016192 181 0.013
dephosphorylation GO:0016311 98 0.013
cellular macromolecule localization GO:0070727 122 0.013
cell cell signaling GO:0007267 335 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
Human
regulation of secretion GO:0051046 224 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
Human Mouse
rho protein signal transduction GO:0007266 11 0.013
Mouse
regulation of cell proliferation GO:0042127 359 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
Human Mouse
nucleotide catabolic process GO:0009166 139 0.012
Human Mouse
anatomical structure morphogenesis GO:0009653 298 0.012
Human Mouse
cellular component morphogenesis GO:0032989 155 0.012
Human Mouse
organic hydroxy compound metabolic process GO:1901615 115 0.012
cell projection morphogenesis GO:0048858 123 0.012
multicellular organism reproduction GO:0032504 233 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
Human Mouse
immune response GO:0006955 104 0.012
single organism catabolic process GO:0044712 283 0.012
Human Mouse
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
Human Mouse
male gamete generation GO:0048232 99 0.012
glycerolipid metabolic process GO:0046486 67 0.012
positive regulation of catabolic process GO:0009896 78 0.012
Human Mouse
regulation of neuron projection development GO:0010975 161 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
Human Mouse
negative regulation of rna metabolic process GO:0051253 123 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of neuron differentiation GO:0045664 208 0.011
regulation of anatomical structure size GO:0090066 135 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
spermatogenesis GO:0007283 99 0.011
regulation of neuron death GO:1901214 115 0.011
metal ion homeostasis GO:0055065 186 0.011
cell cycle checkpoint GO:0000075 2 0.011
response to toxic substance GO:0009636 133 0.011
cellular response to peptide GO:1901653 133 0.011
Human
cellular response to growth factor stimulus GO:0071363 162 0.011
regulation of endocytosis GO:0030100 42 0.011
cytoskeleton organization GO:0007010 111 0.011
Human Mouse
muscle system process GO:0003012 115 0.011
Rat
single organism reproductive process GO:0044702 297 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
Human Rat
positive regulation of neuron differentiation GO:0045666 126 0.011
response to nutrient GO:0007584 248 0.011
calcium ion transport GO:0006816 131 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
Human Mouse
intracellular transport GO:0046907 185 0.011
Rat
response to insulin GO:0032868 133 0.011
oxidation reduction process GO:0055114 304 0.011
neuron projection morphogenesis GO:0048812 122 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
negative regulation of innate immune response GO:0045824 4 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
cell part morphogenesis GO:0032990 123 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
Human Mouse
sexual reproduction GO:0019953 148 0.011
establishment of protein localization GO:0045184 141 0.011
negative regulation of signal transduction GO:0009968 83 0.011
divalent inorganic cation transport GO:0072511 134 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
Human Mouse
response to carbohydrate GO:0009743 183 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.010
response to nutrient levels GO:0031667 370 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
positive regulation of cell development GO:0010720 176 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
Human
axis specification GO:0009798 4 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
Human Mouse
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
Human Mouse
protein transport GO:0015031 132 0.010
positive regulation of signal transduction GO:0009967 175 0.010
response to biotic stimulus GO:0009607 226 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
cellular ion homeostasis GO:0006873 184 0.010
response to hydrogen peroxide GO:0042542 89 0.010
mapk cascade GO:0000165 140 0.010
regulation of neurogenesis GO:0050767 247 0.010
Mouse
gastrulation GO:0007369 2 0.010
regulation of system process GO:0044057 208 0.010
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.010

Arhgef2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.012
retinal disease DOID:5679 0 0.010