Rattus norvegicus

0 known processes

Traf4

Tnf receptor associated factor 4

Traf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.183
intracellular signal transduction GO:0035556 314 0.180
Fly
regulation of rna biosynthetic process GO:2001141 381 0.133
regulation of transcription dna templated GO:0006355 374 0.118
nucleic acid templated transcription GO:0097659 379 0.111
regulation of nucleic acid templated transcription GO:1903506 380 0.110
transcription dna templated GO:0006351 377 0.107
neuron development GO:0048666 286 0.094
negative regulation of cellular metabolic process GO:0031324 281 0.091
cation transport GO:0006812 382 0.083
cell projection organization GO:0030030 302 0.082
rna metabolic process GO:0016070 406 0.081
regulation of protein metabolic process GO:0051246 289 0.078
rna biosynthetic process GO:0032774 380 0.075
negative regulation of macromolecule metabolic process GO:0010605 260 0.073
negative regulation of nucleic acid templated transcription GO:1903507 117 0.071
transcription from rna polymerase ii promoter GO:0006366 252 0.070
response to nutrient levels GO:0031667 370 0.070
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.067
negative regulation of metabolic process GO:0009892 331 0.067
neuron differentiation GO:0030182 368 0.067
regulation of cellular protein metabolic process GO:0032268 267 0.063
regulation of phosphorus metabolic process GO:0051174 349 0.062
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.061
regulation of phosphate metabolic process GO:0019220 349 0.061
Fly
regulation of molecular function GO:0065009 398 0.059
negative regulation of gene expression GO:0010629 199 0.058
regulation of catalytic activity GO:0050790 304 0.058
negative regulation of transcription dna templated GO:0045892 116 0.057
regulation of signal transduction GO:0009966 318 0.057
Fly
regulation of neuron differentiation GO:0045664 208 0.057
negative regulation of cellular biosynthetic process GO:0031327 161 0.056
cellular component morphogenesis GO:0032989 155 0.054
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.053
regulation of cellular component organization GO:0051128 368 0.053
positive regulation of signaling GO:0023056 270 0.052
Fly
central nervous system development GO:0007417 311 0.052
regulation of nervous system development GO:0051960 264 0.052
positive regulation of phosphate metabolic process GO:0045937 262 0.051
Fly
cellular response to stress GO:0033554 269 0.051
Fly
organelle organization GO:0006996 266 0.050
negative regulation of biosynthetic process GO:0009890 168 0.049
programmed cell death GO:0012501 392 0.049
Fly
protein localization GO:0008104 191 0.049
Fly
macromolecule localization GO:0033036 252 0.049
Fly
regulation of cell proliferation GO:0042127 359 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
macromolecular complex subunit organization GO:0043933 339 0.045
cellular amino acid metabolic process GO:0006520 107 0.044
positive regulation of apoptotic process GO:0043065 154 0.044
Fly
positive regulation of cell communication GO:0010647 271 0.044
Fly
cellular response to oxygen containing compound GO:1901701 386 0.044
regulation of cell differentiation GO:0045595 320 0.043
response to wounding GO:0009611 254 0.043
apoptotic process GO:0006915 381 0.043
Fly
positive regulation of programmed cell death GO:0043068 157 0.042
Fly
purine ribonucleotide metabolic process GO:0009150 227 0.041
regulation of protein modification process GO:0031399 194 0.041
regulation of cell projection organization GO:0031344 175 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
protein complex biogenesis GO:0070271 263 0.040
single organism reproductive process GO:0044702 297 0.040
cellular component biogenesis GO:0044085 368 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
positive regulation of gene expression GO:0010628 244 0.038
brain development GO:0007420 247 0.038
cellular amine metabolic process GO:0044106 38 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
Fly
amine metabolic process GO:0009308 38 0.038
negative regulation of rna biosynthetic process GO:1902679 118 0.037
positive regulation of cellular protein metabolic process GO:0032270 167 0.037
cellular catabolic process GO:0044248 295 0.037
regulation of neurogenesis GO:0050767 247 0.037
positive regulation of protein metabolic process GO:0051247 178 0.037
microvillus assembly GO:0030033 2 0.037
protein phosphorylation GO:0006468 345 0.036
protein complex subunit organization GO:0071822 302 0.036
response to peptide GO:1901652 292 0.035
response to extracellular stimulus GO:0009991 380 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.035
neuron projection development GO:0031175 273 0.035
cellular component assembly GO:0022607 360 0.035
regulation of intracellular signal transduction GO:1902531 218 0.034
Fly
regulation of cell development GO:0060284 263 0.034
regulation of apoptotic process GO:0042981 335 0.034
Fly
positive regulation of nervous system development GO:0051962 178 0.034
regulation of phosphorylation GO:0042325 248 0.034
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
response to acid chemical GO:0001101 222 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
Fly
response to hypoxia GO:0001666 231 0.033
sensory organ development GO:0007423 74 0.033
Fly
response to nutrient GO:0007584 248 0.033
protein complex assembly GO:0006461 263 0.032
carboxylic acid metabolic process GO:0019752 289 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
response to peptide hormone GO:0043434 278 0.031
macromolecular complex assembly GO:0065003 273 0.031
response to inorganic substance GO:0010035 377 0.030
regulation of catabolic process GO:0009894 113 0.030
reproductive process GO:0022414 372 0.030
organic substance catabolic process GO:1901575 316 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
single organism organelle organization GO:1902589 180 0.029
coenzyme metabolic process GO:0006732 86 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
head development GO:0060322 247 0.029
ion transmembrane transport GO:0034220 365 0.028
regulation of programmed cell death GO:0043067 341 0.028
Fly
nucleoside phosphate metabolic process GO:0006753 283 0.028
regulation of neuron projection development GO:0010975 161 0.028
tissue development GO:0009888 252 0.028
Fly
regulation of proteasomal protein catabolic process GO:0061136 4 0.028
response to oxygen levels GO:0070482 265 0.027
multicellular organism reproduction GO:0032504 233 0.027
regulation of cellular catabolic process GO:0031329 101 0.027
establishment of tissue polarity GO:0007164 2 0.027
response to metal ion GO:0010038 253 0.026
nucleotide metabolic process GO:0009117 279 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.026
Fly
positive regulation of protein modification process GO:0031401 142 0.026
regulation of protein kinase activity GO:0045859 105 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
positive regulation of cellular component organization GO:0051130 200 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
gland development GO:0048732 155 0.025
Fly
cellular ketone metabolic process GO:0042180 51 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
Fly
regulation of protein phosphorylation GO:0001932 183 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
positive regulation of neuron projection development GO:0010976 99 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
purine containing compound metabolic process GO:0072521 253 0.024
cell migration GO:0016477 197 0.024
response to carbohydrate GO:0009743 183 0.024
multi organism reproductive process GO:0044703 262 0.023
regulation of organelle organization GO:0033043 80 0.023
cell morphogenesis GO:0000902 142 0.023
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of cellular localization GO:0060341 263 0.023
protein oligomerization GO:0051259 191 0.022
regulation of cellular response to stress GO:0080135 49 0.022
Fly
positive regulation of cell differentiation GO:0045597 217 0.022
cellular component movement GO:0006928 248 0.022
Fly
proteolysis GO:0006508 175 0.022
cell adhesion GO:0007155 110 0.022
catabolic process GO:0009056 351 0.022
organ morphogenesis GO:0009887 75 0.021
Fly
ras protein signal transduction GO:0007265 29 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
Fly
positive regulation of molecular function GO:0044093 230 0.021
cell cycle checkpoint GO:0000075 2 0.021
locomotion GO:0040011 237 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
cellular response to endogenous stimulus GO:0071495 377 0.020
positive regulation of developmental process GO:0051094 283 0.020
female pregnancy GO:0007565 122 0.020
chromosome segregation GO:0007059 2 0.020
cell motility GO:0048870 202 0.020
organic acid metabolic process GO:0006082 292 0.020
heterocycle catabolic process GO:0046700 167 0.020
response to decreased oxygen levels GO:0036293 237 0.019
negative regulation of signaling GO:0023057 157 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
negative regulation of molecular function GO:0044092 133 0.019
regulation of transferase activity GO:0051338 123 0.019
cellular protein localization GO:0034613 122 0.019
negative regulation of cell communication GO:0010648 158 0.019
organophosphate metabolic process GO:0019637 370 0.019
response to vitamin GO:0033273 131 0.018
response to estradiol GO:0032355 164 0.018
cellular response to external stimulus GO:0071496 118 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
cell cycle GO:0007049 101 0.018
positive regulation of cell development GO:0010720 176 0.018
cell projection morphogenesis GO:0048858 123 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
epithelial cell differentiation GO:0030855 71 0.017
Fly
cellular response to nitrogen compound GO:1901699 210 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
dna metabolic process GO:0006259 96 0.017
reproduction GO:0000003 245 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
anion transport GO:0006820 178 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
homeostatic process GO:0042592 331 0.017
regulation of membrane potential GO:0042391 110 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of catalytic activity GO:0043085 184 0.016
single organism biosynthetic process GO:0044711 342 0.016
cell junction organization GO:0034330 21 0.016
Fly
response to estrogen GO:0043627 232 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
chemical homeostasis GO:0048878 292 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
cation transmembrane transport GO:0098655 263 0.016
nucleoside metabolic process GO:0009116 179 0.016
metal ion transport GO:0030001 289 0.016
biological adhesion GO:0022610 110 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
regulation of dendrite development GO:0050773 59 0.015
response to transforming growth factor beta GO:0071559 46 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
aging GO:0007568 241 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
cellular homeostasis GO:0019725 252 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
epithelium development GO:0060429 96 0.015
Fly
single organism membrane organization GO:0044802 74 0.015
mapk cascade GO:0000165 140 0.015
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
rhythmic process GO:0048511 156 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
oxidation reduction process GO:0055114 304 0.014
embryonic pattern specification GO:0009880 1 0.014
inner ear morphogenesis GO:0042472 1 0.014
response to glucocorticoid GO:0051384 223 0.014
cell cycle process GO:0022402 57 0.014
glial cell differentiation GO:0010001 65 0.014
cellular chemical homeostasis GO:0055082 247 0.014
cell part morphogenesis GO:0032990 123 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
lipid storage GO:0019915 1 0.014
oxoacid metabolic process GO:0043436 290 0.014
negative regulation of developmental process GO:0051093 125 0.014
gastrulation GO:0007369 2 0.014
Fly
ion homeostasis GO:0050801 212 0.014
intracellular transport GO:0046907 185 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
mechanoreceptor differentiation GO:0042490 2 0.014
mesoderm development GO:0007498 2 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
tube development GO:0035295 89 0.014
Fly
response to growth factor GO:0070848 189 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of anatomical structure size GO:0090066 135 0.013
single organism catabolic process GO:0044712 283 0.013
response to organophosphorus GO:0046683 102 0.013
regulation of cell cycle GO:0051726 73 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
tissue morphogenesis GO:0048729 22 0.013
positive regulation of cell death GO:0010942 184 0.013
Fly
purine ribonucleoside metabolic process GO:0046128 168 0.013
localization of cell GO:0051674 202 0.013
positive regulation of mitochondrion organization GO:0010822 4 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.013
regulation of response to stress GO:0080134 126 0.013
Fly
defense response GO:0006952 194 0.013
Fly
response to purine containing compound GO:0014074 126 0.013
neurological system process GO:0050877 219 0.013
actin filament based process GO:0030029 86 0.013
Fly
anterior posterior pattern specification GO:0009952 1 0.013
response to axon injury GO:0048678 59 0.013
heart morphogenesis GO:0003007 3 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
nucleotide catabolic process GO:0009166 139 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
developmental process involved in reproduction GO:0003006 159 0.013
cellular macromolecule localization GO:0070727 122 0.013
positive regulation of signal transduction GO:0009967 175 0.012
Fly
purine nucleotide metabolic process GO:0006163 229 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
regulation of mapk cascade GO:0043408 116 0.012
Fly
gtp catabolic process GO:0006184 71 0.012
transmembrane transport GO:0055085 412 0.012
cellular cation homeostasis GO:0030003 180 0.012
histone h3 acetylation GO:0043966 2 0.012
dna integrity checkpoint GO:0031570 2 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cell cell signaling GO:0007267 335 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
gliogenesis GO:0042063 93 0.012
purine containing compound catabolic process GO:0072523 138 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
regeneration GO:0031099 163 0.012
sexual reproduction GO:0019953 148 0.012
carbohydrate metabolic process GO:0005975 130 0.011
positive regulation of transferase activity GO:0051347 81 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
response to ketone GO:1901654 182 0.011
response to hexose GO:0009746 144 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
circadian rhythm GO:0007623 88 0.011
folic acid containing compound metabolic process GO:0006760 10 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
response to camp GO:0051591 91 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
response to corticosteroid GO:0031960 235 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of intracellular transport GO:0032386 65 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of catabolic process GO:0009896 78 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
jak stat cascade GO:0007259 26 0.011
peptidyl amino acid modification GO:0018193 126 0.011
dna packaging GO:0006323 4 0.011
morphogenesis of a polarized epithelium GO:0001738 1 0.011
cell substrate adhesion GO:0031589 29 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
response to alkaloid GO:0043279 132 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
response to toxic substance GO:0009636 133 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
chromatin assembly or disassembly GO:0006333 1 0.011
organic acid transport GO:0015849 116 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.010
protein homooligomerization GO:0051260 91 0.010
sulfur compound metabolic process GO:0006790 70 0.010
synaptic transmission GO:0007268 235 0.010
action potential GO:0001508 54 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
Fly
morphogenesis of embryonic epithelium GO:0016331 3 0.010
axis specification GO:0009798 4 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
dendrite development GO:0016358 72 0.010
muscle cell proliferation GO:0033002 84 0.010
inner ear receptor cell differentiation GO:0060113 2 0.010
negative regulation of transport GO:0051051 136 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
single organism intracellular transport GO:1902582 166 0.010
glucose metabolic process GO:0006006 52 0.010
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.010
anion transmembrane transport GO:0098656 77 0.010

Traf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
nervous system disease DOID:863 0 0.015
large intestine cancer DOID:5672 0 0.013
colon cancer DOID:219 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
colorectal cancer DOID:9256 0 0.013
colon carcinoma DOID:1520 0 0.011