Rattus norvegicus

0 known processes

Alms1

Alstrom syndrome 1 homolog (human)

Alms1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.035
oxoacid metabolic process GO:0043436 290 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.034
rna metabolic process GO:0016070 406 0.033
protein phosphorylation GO:0006468 345 0.032
regulation of rna biosynthetic process GO:2001141 381 0.031
organophosphate metabolic process GO:0019637 370 0.031
organic acid metabolic process GO:0006082 292 0.031
rna biosynthetic process GO:0032774 380 0.029
intracellular signal transduction GO:0035556 314 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
nucleic acid templated transcription GO:0097659 379 0.027
transcription dna templated GO:0006351 377 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
amine metabolic process GO:0009308 38 0.027
nucleotide metabolic process GO:0009117 279 0.027
reproductive process GO:0022414 372 0.026
cellular amine metabolic process GO:0044106 38 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
regulation of transcription dna templated GO:0006355 374 0.026
negative regulation of metabolic process GO:0009892 331 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
cellular ketone metabolic process GO:0042180 51 0.025
cellular component biogenesis GO:0044085 368 0.025
neuron differentiation GO:0030182 368 0.025
response to inorganic substance GO:0010035 377 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
cellular component assembly GO:0022607 360 0.025
single organism biosynthetic process GO:0044711 342 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
catabolic process GO:0009056 351 0.024
positive regulation of developmental process GO:0051094 283 0.024
regulation of rna metabolic process GO:0051252 391 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
regulation of cellular component organization GO:0051128 368 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of molecular function GO:0065009 398 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
multi organism reproductive process GO:0044703 262 0.023
programmed cell death GO:0012501 392 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
single organism reproductive process GO:0044702 297 0.023
regulation of catalytic activity GO:0050790 304 0.023
regulation of cellular localization GO:0060341 263 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of cell differentiation GO:0045595 320 0.022
homeostatic process GO:0042592 331 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
protein complex assembly GO:0006461 263 0.021
macromolecular complex assembly GO:0065003 273 0.021
protein complex subunit organization GO:0071822 302 0.021
macromolecule localization GO:0033036 252 0.021
response to extracellular stimulus GO:0009991 380 0.021
negative regulation of cell death GO:0060548 229 0.021
response to nutrient levels GO:0031667 370 0.020
central nervous system development GO:0007417 311 0.020
reproduction GO:0000003 245 0.020
cellular component movement GO:0006928 248 0.020
apoptotic process GO:0006915 381 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
positive regulation of nervous system development GO:0051962 178 0.020
protein complex biogenesis GO:0070271 263 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
response to metal ion GO:0010038 253 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
cell projection organization GO:0030030 302 0.020
secretion GO:0046903 307 0.020
positive regulation of signaling GO:0023056 270 0.020
regulation of phosphorylation GO:0042325 248 0.019
cellular catabolic process GO:0044248 295 0.019
organelle organization GO:0006996 266 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of signal transduction GO:0009966 318 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
neuron projection development GO:0031175 273 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
positive regulation of gene expression GO:0010628 244 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
regulation of cell development GO:0060284 263 0.019
regulation of neurogenesis GO:0050767 247 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
positive regulation of neurogenesis GO:0050769 165 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
neuron development GO:0048666 286 0.018
organic substance catabolic process GO:1901575 316 0.018
positive regulation of cell development GO:0010720 176 0.018
regulation of apoptotic process GO:0042981 335 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
single organism catabolic process GO:0044712 283 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of programmed cell death GO:0043067 341 0.018
multicellular organism reproduction GO:0032504 233 0.018
regulation of protein metabolic process GO:0051246 289 0.018
secretion by cell GO:0032940 248 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
positive regulation of cell communication GO:0010647 271 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
chemical homeostasis GO:0048878 292 0.017
neurological system process GO:0050877 219 0.017
regulation of neuron differentiation GO:0045664 208 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
aging GO:0007568 241 0.017
nitrogen compound transport GO:0071705 229 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
response to peptide GO:1901652 292 0.017
head development GO:0060322 247 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
positive regulation of molecular function GO:0044093 230 0.017
anterior posterior pattern specification GO:0009952 1 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
cation transport GO:0006812 382 0.016
cellular homeostasis GO:0019725 252 0.016
lipid metabolic process GO:0006629 283 0.016
response to nutrient GO:0007584 248 0.016
single organism organelle organization GO:1902589 180 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
transmembrane transport GO:0055085 412 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
heterocycle catabolic process GO:0046700 167 0.016
response to hypoxia GO:0001666 231 0.016
intracellular transport GO:0046907 185 0.016
ion transmembrane transport GO:0034220 365 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
regulation of secretion GO:0051046 224 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
locomotion GO:0040011 237 0.015
negative regulation of gene expression GO:0010629 199 0.015
response to monosaccharide GO:0034284 159 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
negative regulation of innate immune response GO:0045824 4 0.015
regulation of protein modification process GO:0031399 194 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
vesicle mediated transport GO:0016192 181 0.015
proteolysis GO:0006508 175 0.015
single organism intracellular transport GO:1902582 166 0.015
cellular response to stress GO:0033554 269 0.014
response to growth factor GO:0070848 189 0.014
metal ion transport GO:0030001 289 0.014
brain development GO:0007420 247 0.014
regulation of hormone levels GO:0010817 187 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
response to oxygen levels GO:0070482 265 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of cell projection organization GO:0031344 175 0.014
sexual reproduction GO:0019953 148 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
response to carbohydrate GO:0009743 183 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of system process GO:0044057 208 0.014
behavior GO:0007610 205 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
response to acid chemical GO:0001101 222 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
response to oxidative stress GO:0006979 186 0.014
positive regulation of transport GO:0051050 245 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
nucleoside metabolic process GO:0009116 179 0.014
response to decreased oxygen levels GO:0036293 237 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cell migration GO:0016477 197 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
signal release GO:0023061 145 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
protein oligomerization GO:0051259 191 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
negative regulation of signaling GO:0023057 157 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
metal ion homeostasis GO:0055065 186 0.013
response to peptide hormone GO:0043434 278 0.013
ras protein signal transduction GO:0007265 29 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
blood circulation GO:0008015 183 0.013
negative regulation of cell communication GO:0010648 158 0.013
cellular lipid metabolic process GO:0044255 208 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
cell cell signaling GO:0007267 335 0.013
ion homeostasis GO:0050801 212 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
response to glucose GO:0009749 136 0.013
regulation of secretion by cell GO:1903530 208 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.013
organophosphate catabolic process GO:0046434 148 0.013
anion transport GO:0006820 178 0.013
cation transmembrane transport GO:0098655 263 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
nucleotide catabolic process GO:0009166 139 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
response to radiation GO:0009314 137 0.013
axis specification GO:0009798 4 0.013
response to glucocorticoid GO:0051384 223 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
chromosome segregation GO:0007059 2 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
response to ethanol GO:0045471 162 0.012
regulation of neuron projection development GO:0010975 161 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
protein localization GO:0008104 191 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of signal transduction GO:0009967 175 0.012
tissue development GO:0009888 252 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
embryonic pattern specification GO:0009880 1 0.012
negative regulation of transport GO:0051051 136 0.012
single organism cellular localization GO:1902580 102 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.012
cellular component morphogenesis GO:0032989 155 0.012
gamete generation GO:0007276 124 0.012
lipid storage GO:0019915 1 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
hormone transport GO:0009914 121 0.012
response to corticosteroid GO:0031960 235 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cell motility GO:0048870 202 0.012
eye morphogenesis GO:0048592 4 0.012
lipid biosynthetic process GO:0008610 128 0.012
cellular chemical homeostasis GO:0055082 247 0.012
localization of cell GO:0051674 202 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
single organism membrane organization GO:0044802 74 0.012
regulation of neuron death GO:1901214 115 0.012
cation homeostasis GO:0055080 195 0.011
regulation of transferase activity GO:0051338 123 0.011
response to hexose GO:0009746 144 0.011
cellular macromolecule localization GO:0070727 122 0.011
protein transport GO:0015031 132 0.011
spermatogenesis GO:0007283 99 0.011
male gamete generation GO:0048232 99 0.011
response to wounding GO:0009611 254 0.011
synaptic transmission GO:0007268 235 0.011
circulatory system process GO:0003013 183 0.011
multi multicellular organism process GO:0044706 138 0.011
cell morphogenesis GO:0000902 142 0.011
cytoplasmic transport GO:0016482 115 0.011
purine containing compound catabolic process GO:0072523 138 0.011
response to estrogen GO:0043627 232 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
developmental growth GO:0048589 100 0.011
peptidyl amino acid modification GO:0018193 126 0.011
establishment of protein localization GO:0045184 141 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
neuron death GO:0070997 127 0.011
hormone secretion GO:0046879 115 0.011
heart morphogenesis GO:0003007 3 0.011
response to biotic stimulus GO:0009607 226 0.011
developmental process involved in reproduction GO:0003006 159 0.011
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.011
aromatic compound catabolic process GO:0019439 168 0.011
dephosphorylation GO:0016311 98 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cell part morphogenesis GO:0032990 123 0.011
carbohydrate metabolic process GO:0005975 130 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
spindle organization GO:0007051 2 0.011
amide transport GO:0042886 105 0.011
rna localization GO:0006403 4 0.011
response to vitamin GO:0033273 131 0.011
regulation of hormone secretion GO:0046883 106 0.011
membrane organization GO:0061024 94 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
regulation of hydrolase activity GO:0051336 143 0.010
response to bacterium GO:0009617 200 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
neuron projection morphogenesis GO:0048812 122 0.010
gastrulation GO:0007369 2 0.010
alternative mrna splicing via spliceosome GO:0000380 4 0.010
positive regulation of cell death GO:0010942 184 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
response to cytokine GO:0034097 215 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
cellular protein localization GO:0034613 122 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
maintenance of location GO:0051235 17 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
cellular cation homeostasis GO:0030003 180 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
peptide transport GO:0015833 97 0.010
regulation of kinase activity GO:0043549 117 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
regeneration GO:0031099 163 0.010
growth GO:0040007 165 0.010

Alms1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
central nervous system disease DOID:331 0 0.016
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.012