Rattus norvegicus

0 known processes

RGD1562378

histone H4 variant H4-v.1

RGD1562378 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.188
single organism biosynthetic process GO:0044711 342 0.175
cellular response to oxygen containing compound GO:1901701 386 0.126
regulation of nervous system development GO:0051960 264 0.115
response to inorganic substance GO:0010035 377 0.086
positive regulation of response to stimulus GO:0048584 285 0.084
regulation of multicellular organismal development GO:2000026 376 0.082
regulation of cellular component organization GO:0051128 368 0.081
intracellular signal transduction GO:0035556 314 0.077
positive regulation of cell communication GO:0010647 271 0.074
signal release GO:0023061 145 0.073
carbohydrate derivative metabolic process GO:1901135 346 0.073
response to wounding GO:0009611 254 0.073
regulation of rna metabolic process GO:0051252 391 0.071
positive regulation of cell proliferation GO:0008284 249 0.070
regulation of phosphorus metabolic process GO:0051174 349 0.069
regulation of cell differentiation GO:0045595 320 0.068
transcription dna templated GO:0006351 377 0.068
carboxylic acid metabolic process GO:0019752 289 0.067
programmed cell death GO:0012501 392 0.066
homeostatic process GO:0042592 331 0.066
regulation of protein metabolic process GO:0051246 289 0.064
positive regulation of signaling GO:0023056 270 0.063
regulation of transcription dna templated GO:0006355 374 0.062
cell cell signaling GO:0007267 335 0.062
anion transport GO:0006820 178 0.062
nucleic acid templated transcription GO:0097659 379 0.061
regulation of intracellular signal transduction GO:1902531 218 0.061
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
secretion by cell GO:0032940 248 0.060
positive regulation of biosynthetic process GO:0009891 319 0.059
negative regulation of macromolecule metabolic process GO:0010605 260 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.057
positive regulation of nervous system development GO:0051962 178 0.057
response to nutrient levels GO:0031667 370 0.056
cellular response to stress GO:0033554 269 0.056
organophosphate metabolic process GO:0019637 370 0.055
cellular lipid metabolic process GO:0044255 208 0.055
lipid biosynthetic process GO:0008610 128 0.054
single organism reproductive process GO:0044702 297 0.052
cellular chemical homeostasis GO:0055082 247 0.052
response to peptide GO:1901652 292 0.052
negative regulation of gene expression GO:0010629 199 0.052
cell projection organization GO:0030030 302 0.051
positive regulation of phosphorus metabolic process GO:0010562 262 0.051
regulation of nucleic acid templated transcription GO:1903506 380 0.049
organelle organization GO:0006996 266 0.049
regulation of cell development GO:0060284 263 0.048
lipid metabolic process GO:0006629 283 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
response to metal ion GO:0010038 253 0.047
negative regulation of cellular metabolic process GO:0031324 281 0.047
positive regulation of neurogenesis GO:0050769 165 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.047
rna biosynthetic process GO:0032774 380 0.047
cellular ion homeostasis GO:0006873 184 0.046
positive regulation of cell development GO:0010720 176 0.046
response to oxygen levels GO:0070482 265 0.044
positive regulation of gene expression GO:0010628 244 0.043
regulation of hormone levels GO:0010817 187 0.043
metal ion transport GO:0030001 289 0.043
regulation of molecular function GO:0065009 398 0.043
neuron differentiation GO:0030182 368 0.042
protein phosphorylation GO:0006468 345 0.041
central nervous system development GO:0007417 311 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.041
regulation of catalytic activity GO:0050790 304 0.040
macromolecule localization GO:0033036 252 0.040
purine containing compound metabolic process GO:0072521 253 0.040
organic acid metabolic process GO:0006082 292 0.040
oxoacid metabolic process GO:0043436 290 0.040
response to biotic stimulus GO:0009607 226 0.039
positive regulation of transcription dna templated GO:0045893 197 0.038
hormone secretion GO:0046879 115 0.038
cellular divalent inorganic cation homeostasis GO:0072503 162 0.038
head development GO:0060322 247 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
cellular component assembly GO:0022607 360 0.038
regulation of rna biosynthetic process GO:2001141 381 0.037
multicellular organism reproduction GO:0032504 233 0.037
positive regulation of developmental process GO:0051094 283 0.037
chemical homeostasis GO:0048878 292 0.037
response to peptide hormone GO:0043434 278 0.037
neuron development GO:0048666 286 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.037
negative regulation of biosynthetic process GO:0009890 168 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
cation transport GO:0006812 382 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
cellular homeostasis GO:0019725 252 0.036
positive regulation of secretion GO:0051047 140 0.036
regulation of transferase activity GO:0051338 123 0.036
response to decreased oxygen levels GO:0036293 237 0.036
regulation of neurogenesis GO:0050767 247 0.036
secretion GO:0046903 307 0.035
neurological system process GO:0050877 219 0.035
neuron projection development GO:0031175 273 0.035
rna metabolic process GO:0016070 406 0.034
negative regulation of cell death GO:0060548 229 0.034
organic acid transport GO:0015849 116 0.034
response to mechanical stimulus GO:0009612 134 0.034
mapk cascade GO:0000165 140 0.034
tissue development GO:0009888 252 0.033
reproduction GO:0000003 245 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
negative regulation of metabolic process GO:0009892 331 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
response to glucose GO:0009749 136 0.032
signal transduction by phosphorylation GO:0023014 144 0.032
regulation of signal transduction GO:0009966 318 0.032
fatty acid metabolic process GO:0006631 99 0.032
response to ketone GO:1901654 182 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
cation homeostasis GO:0055080 195 0.031
response to growth factor GO:0070848 189 0.031
negative regulation of signaling GO:0023057 157 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
regulation of protein modification process GO:0031399 194 0.031
metal ion homeostasis GO:0055065 186 0.031
regulation of growth GO:0040008 105 0.030
response to carbohydrate GO:0009743 183 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
response to nutrient GO:0007584 248 0.030
cellular component biogenesis GO:0044085 368 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
ion homeostasis GO:0050801 212 0.030
regulation of cellular localization GO:0060341 263 0.029
response to hexose GO:0009746 144 0.029
cellular cation homeostasis GO:0030003 180 0.029
response to monosaccharide GO:0034284 159 0.029
regulation of apoptotic process GO:0042981 335 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
regulation of cell proliferation GO:0042127 359 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
hormone transport GO:0009914 121 0.028
reproductive process GO:0022414 372 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
response to external biotic stimulus GO:0043207 221 0.028
cellular response to acid chemical GO:0071229 75 0.028
regulation of programmed cell death GO:0043067 341 0.028
cellular response to endogenous stimulus GO:0071495 377 0.027
negative regulation of cell proliferation GO:0008285 119 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
development of primary sexual characteristics GO:0045137 107 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
transmembrane transport GO:0055085 412 0.027
regulation of nucleotide metabolic process GO:0006140 117 0.026
cellular ketone metabolic process GO:0042180 51 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
response to corticosteroid GO:0031960 235 0.026
regulation of neuron differentiation GO:0045664 208 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
apoptotic process GO:0006915 381 0.026
gonad development GO:0008406 104 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
regulation of homeostatic process GO:0032844 101 0.026
response to cytokine GO:0034097 215 0.026
cellular response to hormone stimulus GO:0032870 247 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
response to estradiol GO:0032355 164 0.025
response to estrogen GO:0043627 232 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
positive regulation of molecular function GO:0044093 230 0.025
regeneration GO:0031099 163 0.024
nitrogen compound transport GO:0071705 229 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
brain development GO:0007420 247 0.024
negative regulation of cell communication GO:0010648 158 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
regulation of mapk cascade GO:0043408 116 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
behavior GO:0007610 205 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
ion transmembrane transport GO:0034220 365 0.023
phospholipid metabolic process GO:0006644 61 0.023
regulation of secretion by cell GO:1903530 208 0.023
cellular amine metabolic process GO:0044106 38 0.023
reproductive system development GO:0061458 128 0.023
positive regulation of signal transduction GO:0009967 175 0.023
protein oligomerization GO:0051259 191 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
cellular calcium ion homeostasis GO:0006874 160 0.022
sensory organ development GO:0007423 74 0.022
protein localization GO:0008104 191 0.022
single organism catabolic process GO:0044712 283 0.022
growth GO:0040007 165 0.022
carboxylic acid transport GO:0046942 115 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
regulation of phosphorylation GO:0042325 248 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
response to hypoxia GO:0001666 231 0.022
regulation of response to stress GO:0080134 126 0.022
response to oxidative stress GO:0006979 186 0.022
regulation of secretion GO:0051046 224 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
response to lipopolysaccharide GO:0032496 191 0.021
cellular response to peptide GO:1901653 133 0.021
protein complex subunit organization GO:0071822 302 0.021
protein complex assembly GO:0006461 263 0.021
regulation of kinase activity GO:0043549 117 0.021
regulation of response to wounding GO:1903034 69 0.021
regulation of response to external stimulus GO:0032101 106 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
wound healing GO:0042060 122 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
tube development GO:0035295 89 0.021
single organism organelle organization GO:1902589 180 0.021
macromolecular complex assembly GO:0065003 273 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
amide transport GO:0042886 105 0.021
small molecule biosynthetic process GO:0044283 124 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
nucleotide metabolic process GO:0009117 279 0.020
neuron death GO:0070997 127 0.020
response to acid chemical GO:0001101 222 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
gliogenesis GO:0042063 93 0.020
response to hydrogen peroxide GO:0042542 89 0.020
positive regulation of protein modification process GO:0031401 142 0.020
single organism behavior GO:0044708 130 0.019
regulation of synaptic transmission GO:0050804 141 0.019
multi organism reproductive process GO:0044703 262 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of system process GO:0044057 208 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
anterior posterior pattern specification GO:0009952 1 0.019
response to reactive oxygen species GO:0000302 120 0.019
cellular metal ion homeostasis GO:0006875 172 0.018
sequestering of metal ion GO:0051238 9 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
circadian rhythm GO:0007623 88 0.018
organic substance catabolic process GO:1901575 316 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
eye morphogenesis GO:0048592 4 0.018
response to temperature stimulus GO:0009266 94 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
response to retinoic acid GO:0032526 63 0.017
protein complex biogenesis GO:0070271 263 0.017
intracellular transport GO:0046907 185 0.017
neurotransmitter secretion GO:0007269 33 0.017
hormone metabolic process GO:0042445 69 0.017
rhythmic process GO:0048511 156 0.017
regulation of dna metabolic process GO:0051052 60 0.016
peptidyl amino acid modification GO:0018193 126 0.016
epithelium development GO:0060429 96 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
muscle system process GO:0003012 115 0.016
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.016
synaptic transmission GO:0007268 235 0.016
negative regulation of molecular function GO:0044092 133 0.016
localization of cell GO:0051674 202 0.016
aging GO:0007568 241 0.016
regulation of cellular component movement GO:0051270 150 0.016
cellular response to lipid GO:0071396 201 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
cellular catabolic process GO:0044248 295 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
positive regulation of transport GO:0051050 245 0.016
maintenance of location GO:0051235 17 0.016
amine metabolic process GO:0009308 38 0.016
response to glucocorticoid GO:0051384 223 0.016
lipid transport GO:0006869 61 0.016
cellular response to organic cyclic compound GO:0071407 202 0.015
sequestering of calcium ion GO:0051208 8 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
muscle contraction GO:0006936 88 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
cell growth GO:0016049 104 0.015
regulation of cell projection organization GO:0031344 175 0.015
circulatory system process GO:0003013 183 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
defense response GO:0006952 194 0.015
vesicle mediated transport GO:0016192 181 0.015
regulation of neuron projection development GO:0010975 161 0.015
small gtpase mediated signal transduction GO:0007264 36 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
regulation of hydrolase activity GO:0051336 143 0.014
proteolysis GO:0006508 175 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
cellular component movement GO:0006928 248 0.014
cellular protein localization GO:0034613 122 0.014
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
regulation of cell motility GO:2000145 131 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
axis specification GO:0009798 4 0.014
lipid localization GO:0010876 62 0.014
peptide secretion GO:0002790 86 0.014
regulation of organelle organization GO:0033043 80 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
olfactory learning GO:0008355 1 0.014
gland development GO:0048732 155 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
response to radiation GO:0009314 137 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
establishment of protein localization GO:0045184 141 0.013
regulation of hormone secretion GO:0046883 106 0.013
aromatic compound catabolic process GO:0019439 168 0.013
sodium ion transport GO:0006814 82 0.013
response to vitamin GO:0033273 131 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cell type specific apoptotic process GO:0097285 134 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
unsaturated fatty acid biosynthetic process GO:0006636 21 0.013
multicellular organismal signaling GO:0035637 44 0.013
sex differentiation GO:0007548 113 0.013
regulation of ion transport GO:0043269 245 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
protein homooligomerization GO:0051260 91 0.013
heterocycle catabolic process GO:0046700 167 0.013
single organism intracellular transport GO:1902582 166 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
multi multicellular organism process GO:0044706 138 0.013
locomotion GO:0040011 237 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
bmp signaling pathway GO:0030509 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
cytoplasmic transport GO:0016482 115 0.012
catabolic process GO:0009056 351 0.012
organic acid biosynthetic process GO:0016053 83 0.012
positive regulation of kinase activity GO:0033674 77 0.012
protein autophosphorylation GO:0046777 66 0.012
protein transport GO:0015031 132 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
positive regulation of transferase activity GO:0051347 81 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
chemosensory behavior GO:0007635 2 0.012
regulation of cell cycle GO:0051726 73 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
female pregnancy GO:0007565 122 0.012
protein heterooligomerization GO:0051291 89 0.012
embryonic pattern specification GO:0009880 1 0.012
olfactory behavior GO:0042048 2 0.012
regulation of synapse organization GO:0050807 19 0.012
spermatogenesis GO:0007283 99 0.012
regulation of cell migration GO:0030334 128 0.012
carbohydrate metabolic process GO:0005975 130 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
cellular response to external stimulus GO:0071496 118 0.011
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
male gonad development GO:0008584 59 0.011
inflammatory response GO:0006954 150 0.011
response to insulin GO:0032868 133 0.011
peptide hormone secretion GO:0030072 84 0.011
forebrain development GO:0030900 98 0.011
ras protein signal transduction GO:0007265 29 0.011
transmission of nerve impulse GO:0019226 42 0.011
response to toxic substance GO:0009636 133 0.011
regulation of protein kinase activity GO:0045859 105 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
regulation of locomotion GO:0040012 148 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
negative regulation of developmental process GO:0051093 125 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
positive regulation of catabolic process GO:0009896 78 0.011
protein maturation GO:0051604 68 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
respiratory system development GO:0060541 45 0.011
response to other organism GO:0051707 220 0.011
reproductive structure development GO:0048608 128 0.011
eye development GO:0001654 50 0.011
action potential GO:0001508 54 0.011
glucose homeostasis GO:0042593 75 0.011
monocarboxylic acid transport GO:0015718 52 0.011
salivary gland development GO:0007431 3 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
heart process GO:0003015 57 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
mesoderm development GO:0007498 2 0.010
regulation of catabolic process GO:0009894 113 0.010
positive regulation of cell motility GO:2000147 97 0.010
negative regulation of nervous system development GO:0051961 79 0.010
gamete generation GO:0007276 124 0.010
learning or memory GO:0007611 90 0.010
cell adhesion GO:0007155 110 0.010
activation of protein kinase activity GO:0032147 47 0.010
nucleoside metabolic process GO:0009116 179 0.010
monosaccharide metabolic process GO:0005996 61 0.010
response to ammonium ion GO:0060359 71 0.010
male sex differentiation GO:0046661 64 0.010
neuronal action potential GO:0019228 35 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
positive regulation of peptide hormone secretion GO:0090277 50 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
organic anion transport GO:0015711 132 0.010

RGD1562378 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.012