Rattus norvegicus

0 known processes

Cldn8

claudin 8

(Aliases: MGC124857)

Cldn8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.075
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
neuron development GO:0048666 286 0.058
growth GO:0040007 165 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.054
response to inorganic substance GO:0010035 377 0.051
positive regulation of rna metabolic process GO:0051254 203 0.050
positive regulation of biosynthetic process GO:0009891 319 0.050
positive regulation of cellular biosynthetic process GO:0031328 295 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.047
oxoacid metabolic process GO:0043436 290 0.046
regulation of nervous system development GO:0051960 264 0.046
positive regulation of cell proliferation GO:0008284 249 0.045
cellular response to oxygen containing compound GO:1901701 386 0.044
cellular amine metabolic process GO:0044106 38 0.044
regulation of transcription dna templated GO:0006355 374 0.044
brain development GO:0007420 247 0.043
multicellular organism reproduction GO:0032504 233 0.043
cellular amino acid metabolic process GO:0006520 107 0.043
cellular component movement GO:0006928 248 0.041
amine metabolic process GO:0009308 38 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.040
inorganic ion transmembrane transport GO:0098660 229 0.040
positive regulation of transcription dna templated GO:0045893 197 0.040
immune system process GO:0002376 204 0.040
regulation of signal transduction GO:0009966 318 0.039
positive regulation of rna biosynthetic process GO:1902680 197 0.038
rna biosynthetic process GO:0032774 380 0.038
positive regulation of developmental process GO:0051094 283 0.037
cell projection morphogenesis GO:0048858 123 0.037
organic acid metabolic process GO:0006082 292 0.036
neuron projection development GO:0031175 273 0.036
regulation of cell differentiation GO:0045595 320 0.035
response to extracellular stimulus GO:0009991 380 0.035
cellular component morphogenesis GO:0032989 155 0.035
cellular response to stress GO:0033554 269 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.033
apoptotic process GO:0006915 381 0.033
rna metabolic process GO:0016070 406 0.033
muscle system process GO:0003012 115 0.033
carboxylic acid metabolic process GO:0019752 289 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
transcription dna templated GO:0006351 377 0.031
neuron differentiation GO:0030182 368 0.031
cell projection organization GO:0030030 302 0.031
response to nutrient levels GO:0031667 370 0.031
central nervous system development GO:0007417 311 0.030
single organism biosynthetic process GO:0044711 342 0.030
cation homeostasis GO:0055080 195 0.030
nucleic acid templated transcription GO:0097659 379 0.030
response to cytokine GO:0034097 215 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
response to acid chemical GO:0001101 222 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
head development GO:0060322 247 0.028
cellular ketone metabolic process GO:0042180 51 0.028
transmembrane transport GO:0055085 412 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
response to wounding GO:0009611 254 0.027
reproductive process GO:0022414 372 0.027
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
cell morphogenesis GO:0000902 142 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
cellular component assembly GO:0022607 360 0.025
reproduction GO:0000003 245 0.025
defense response GO:0006952 194 0.025
axon development GO:0061564 96 0.025
single organism reproductive process GO:0044702 297 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
programmed cell death GO:0012501 392 0.024
tissue development GO:0009888 252 0.024
cell part morphogenesis GO:0032990 123 0.024
regulation of programmed cell death GO:0043067 341 0.024
regulation of cellular component organization GO:0051128 368 0.023
positive regulation of gene expression GO:0010628 244 0.023
homeostatic process GO:0042592 331 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
regulation of neurogenesis GO:0050767 247 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
response to mechanical stimulus GO:0009612 134 0.022
cell growth GO:0016049 104 0.022
response to oxidative stress GO:0006979 186 0.022
regulation of rna metabolic process GO:0051252 391 0.021
cellular response to peptide GO:1901653 133 0.021
cellular cation homeostasis GO:0030003 180 0.021
protein phosphorylation GO:0006468 345 0.021
negative regulation of metabolic process GO:0009892 331 0.021
neuron projection morphogenesis GO:0048812 122 0.021
blood circulation GO:0008015 183 0.021
regulation of cell projection organization GO:0031344 175 0.021
metal ion homeostasis GO:0055065 186 0.020
organelle organization GO:0006996 266 0.020
regulation of growth GO:0040008 105 0.020
positive regulation of protein modification process GO:0031401 142 0.020
cellular homeostasis GO:0019725 252 0.020
cellular lipid metabolic process GO:0044255 208 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
response to metal ion GO:0010038 253 0.020
positive regulation of signaling GO:0023056 270 0.019
response to estrogen GO:0043627 232 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
anion transport GO:0006820 178 0.019
anion transmembrane transport GO:0098656 77 0.019
locomotion GO:0040011 237 0.019
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
regulation of intracellular signal transduction GO:1902531 218 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
regulation of apoptotic process GO:0042981 335 0.018
intracellular signal transduction GO:0035556 314 0.018
nucleotide metabolic process GO:0009117 279 0.018
negative regulation of cell death GO:0060548 229 0.018
response to nutrient GO:0007584 248 0.017
regulation of establishment of planar polarity GO:0090175 2 0.017
regulation of membrane potential GO:0042391 110 0.017
positive regulation of cell communication GO:0010647 271 0.017
positive regulation of immunoglobulin production GO:0002639 4 0.017
neurological system process GO:0050877 219 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
calcium ion homeostasis GO:0055074 162 0.016
cellular response to reactive oxygen species GO:0034614 55 0.016
response to alkaloid GO:0043279 132 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
regulation of response to stress GO:0080134 126 0.016
regulation of cell growth GO:0001558 85 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
non canonical wnt signaling pathway GO:0035567 3 0.016
ion transmembrane transport GO:0034220 365 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
regulation of body fluid levels GO:0050878 90 0.016
circulatory system process GO:0003013 183 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
regulation of molecular function GO:0065009 398 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
response to oxygen levels GO:0070482 265 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
catabolic process GO:0009056 351 0.016
tube development GO:0035295 89 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
heart morphogenesis GO:0003007 3 0.015
ion homeostasis GO:0050801 212 0.015
response to vitamin GO:0033273 131 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of system process GO:0044057 208 0.015
regulation of cell development GO:0060284 263 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
female pregnancy GO:0007565 122 0.015
Rat
cellular response to endogenous stimulus GO:0071495 377 0.015
regulation of response to external stimulus GO:0032101 106 0.015
rhythmic process GO:0048511 156 0.015
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
establishment of tissue polarity GO:0007164 2 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
multi organism reproductive process GO:0044703 262 0.015
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cell motility GO:0048870 202 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
wound healing GO:0042060 122 0.014
organ morphogenesis GO:0009887 75 0.014
regulation of cellular localization GO:0060341 263 0.014
telencephalon development GO:0021537 62 0.014
inflammatory response GO:0006954 150 0.014
aging GO:0007568 241 0.014
regulation of neuron projection development GO:0010975 161 0.014
single organism catabolic process GO:0044712 283 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
response to corticosteroid GO:0031960 235 0.014
macromolecular complex assembly GO:0065003 273 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of cell death GO:0010942 184 0.014
cation transport GO:0006812 382 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
response to peptide hormone GO:0043434 278 0.013
macromolecule localization GO:0033036 252 0.013
regulation of tube size GO:0035150 89 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
regulation of anatomical structure size GO:0090066 135 0.013
cellular response to external stimulus GO:0071496 118 0.013
regulation of protein modification process GO:0031399 194 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.013
salivary gland development GO:0007431 3 0.013
regulation of protein metabolic process GO:0051246 289 0.013
sodium ion transport GO:0006814 82 0.013
response to ketone GO:1901654 182 0.013
Rat
action potential GO:0001508 54 0.013
axis specification GO:0009798 4 0.013
response to estradiol GO:0032355 164 0.013
chemotaxis GO:0006935 66 0.013
gliogenesis GO:0042063 93 0.013
response to decreased oxygen levels GO:0036293 237 0.013
cell activation GO:0001775 97 0.013
negative regulation of gene expression GO:0010629 199 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
sensory perception GO:0007600 101 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
immunoglobulin mediated immune response GO:0016064 4 0.012
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.012
vesicle mediated transport GO:0016192 181 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
single organism organelle organization GO:1902589 180 0.012
cellular chemical homeostasis GO:0055082 247 0.012
protein complex biogenesis GO:0070271 263 0.012
ras protein signal transduction GO:0007265 29 0.012
salivary gland morphogenesis GO:0007435 1 0.012
response to reactive oxygen species GO:0000302 120 0.012
gonad development GO:0008406 104 0.012
sensory perception of bitter taste GO:0050913 4 0.012
regulation of blood vessel size GO:0050880 89 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
response to growth factor GO:0070848 189 0.012
positive regulation of cell development GO:0010720 176 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
embryonic skeletal system development GO:0048706 3 0.012
secretion GO:0046903 307 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
small molecule biosynthetic process GO:0044283 124 0.012
response to biotic stimulus GO:0009607 226 0.012
protein localization GO:0008104 191 0.011
platelet derived growth factor production GO:0090360 2 0.011
organophosphate metabolic process GO:0019637 370 0.011
gamete generation GO:0007276 124 0.011
regulation of neuron differentiation GO:0045664 208 0.011
lipid metabolic process GO:0006629 283 0.011
developmental process involved in reproduction GO:0003006 159 0.011
proteolysis GO:0006508 175 0.011
regulation of locomotion GO:0040012 148 0.011
regulation of protein localization GO:0032880 81 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
morphogenesis of a polarized epithelium GO:0001738 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
response to glucocorticoid GO:0051384 223 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
sulfur compound metabolic process GO:0006790 70 0.011
cellular component biogenesis GO:0044085 368 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
reproductive system development GO:0061458 128 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
nitrogen compound transport GO:0071705 229 0.011
response to hypoxia GO:0001666 231 0.011
cellular catabolic process GO:0044248 295 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
cellular ion homeostasis GO:0006873 184 0.011
regulation of mesenchymal cell proliferation GO:0010464 4 0.011
developmental growth GO:0048589 100 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
cation transmembrane transport GO:0098655 263 0.011
response to bacterium GO:0009617 200 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
anterior posterior pattern specification GO:0009952 1 0.011
hepaticobiliary system development GO:0061008 90 0.011
response to hydrogen peroxide GO:0042542 89 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
localization of cell GO:0051674 202 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
response to other organism GO:0051707 220 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
b cell differentiation GO:0030183 2 0.010
sexual reproduction GO:0019953 148 0.010
embryonic pattern specification GO:0009880 1 0.010
purine containing compound metabolic process GO:0072521 253 0.010
regulation of ion transport GO:0043269 245 0.010
secretion by cell GO:0032940 248 0.010
axonogenesis GO:0007409 71 0.010
response to corticosterone GO:0051412 40 0.010
response to peptide GO:1901652 292 0.010
reproductive structure development GO:0048608 128 0.010
muscle contraction GO:0006936 88 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
positive regulation of growth GO:0045927 55 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
inorganic anion transport GO:0015698 41 0.010
regulation of protein transport GO:0051223 68 0.010
chemokine metabolic process GO:0050755 3 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
chemical homeostasis GO:0048878 292 0.010

Cldn8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
sensory system disease DOID:0050155 0 0.013