Rattus norvegicus

45 known processes

Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

(Aliases: raPIT5a,PI-12)

Serpini1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 302 0.114
Rat
response to peptide hormone GO:0043434 278 0.112
Rat
regulation of cellular component organization GO:0051128 368 0.108
Rat
macromolecular complex subunit organization GO:0043933 339 0.098
neuron development GO:0048666 286 0.094
Rat
regulation of cell differentiation GO:0045595 320 0.092
Rat
positive regulation of nervous system development GO:0051962 178 0.091
Rat
response to inorganic substance GO:0010035 377 0.077
Rat
regulation of nervous system development GO:0051960 264 0.076
Rat
nucleotide metabolic process GO:0009117 279 0.073
neuron projection development GO:0031175 273 0.071
Rat
neuron differentiation GO:0030182 368 0.071
Rat
positive regulation of cellular component organization GO:0051130 200 0.068
Rat
central nervous system development GO:0007417 311 0.067
nucleobase containing small molecule metabolic process GO:0055086 316 0.066
intracellular signal transduction GO:0035556 314 0.065
single organism biosynthetic process GO:0044711 342 0.065
single organism reproductive process GO:0044702 297 0.064
Rat
protein complex biogenesis GO:0070271 263 0.064
cellular component biogenesis GO:0044085 368 0.064
Rat
macromolecular complex assembly GO:0065003 273 0.063
organic acid metabolic process GO:0006082 292 0.063
oxoacid metabolic process GO:0043436 290 0.062
nucleoside phosphate metabolic process GO:0006753 283 0.061
organic substance catabolic process GO:1901575 316 0.060
Rat
regulation of neuron differentiation GO:0045664 208 0.059
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.059
positive regulation of neuron projection development GO:0010976 99 0.058
Rat
purine containing compound metabolic process GO:0072521 253 0.058
catabolic process GO:0009056 351 0.056
Rat
positive regulation of cell projection organization GO:0031346 111 0.054
Rat
transmembrane transport GO:0055085 412 0.053
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.050
protein complex assembly GO:0006461 263 0.049
regulation of cell projection organization GO:0031344 175 0.049
Rat
regulation of cell development GO:0060284 263 0.049
Rat
cellular component assembly GO:0022607 360 0.049
cellular amino acid metabolic process GO:0006520 107 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
anion transport GO:0006820 178 0.046
response to extracellular stimulus GO:0009991 380 0.044
Rat
carboxylic acid metabolic process GO:0019752 289 0.044
protein oligomerization GO:0051259 191 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
multi organism reproductive process GO:0044703 262 0.043
Rat
single organism intracellular transport GO:1902582 166 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
positive regulation of developmental process GO:0051094 283 0.043
Rat
cellular catabolic process GO:0044248 295 0.043
purine nucleotide metabolic process GO:0006163 229 0.042
response to nutrient levels GO:0031667 370 0.042
Rat
positive regulation of response to stimulus GO:0048584 285 0.042
cation transport GO:0006812 382 0.042
Rat
regulation of multicellular organismal development GO:2000026 376 0.042
Rat
reproductive process GO:0022414 372 0.041
Rat
regulation of molecular function GO:0065009 398 0.039
negative regulation of metabolic process GO:0009892 331 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
regulation of protein metabolic process GO:0051246 289 0.039
regulation of catalytic activity GO:0050790 304 0.039
regulation of phosphate metabolic process GO:0019220 349 0.038
single organism catabolic process GO:0044712 283 0.038
protein complex subunit organization GO:0071822 302 0.037
organic acid transport GO:0015849 116 0.036
response to peptide GO:1901652 292 0.036
Rat
ribose phosphate metabolic process GO:0019693 235 0.035
organophosphate metabolic process GO:0019637 370 0.035
regulation of cellular localization GO:0060341 263 0.035
regulation of hydrolase activity GO:0051336 143 0.034
cellular response to stress GO:0033554 269 0.034
Rat
vesicle mediated transport GO:0016192 181 0.034
Rat
brain development GO:0007420 247 0.034
response to metal ion GO:0010038 253 0.034
Rat
positive regulation of gene expression GO:0010628 244 0.034
Rat
protein homooligomerization GO:0051260 91 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
Rat
nucleoside metabolic process GO:0009116 179 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
response to oxygen levels GO:0070482 265 0.033
Rat
organophosphate catabolic process GO:0046434 148 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.032
ribonucleotide metabolic process GO:0009259 231 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
Rat
regulation of transcription dna templated GO:0006355 374 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
cellular amine metabolic process GO:0044106 38 0.030
neuron apoptotic process GO:0051402 88 0.030
head development GO:0060322 247 0.030
regulation of phosphorylation GO:0042325 248 0.030
purine nucleoside metabolic process GO:0042278 169 0.030
programmed cell death GO:0012501 392 0.030
positive regulation of neuron differentiation GO:0045666 126 0.030
Rat
cellular response to oxygen containing compound GO:1901701 386 0.030
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
Rat
regulation of signal transduction GO:0009966 318 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
Rat
positive regulation of cell development GO:0010720 176 0.028
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
apoptotic process GO:0006915 381 0.028
ribonucleoside metabolic process GO:0009119 174 0.028
regulation of rna metabolic process GO:0051252 391 0.027
neurological system process GO:0050877 219 0.027
multi multicellular organism process GO:0044706 138 0.027
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.027
response to wounding GO:0009611 254 0.027
Rat
regulation of cell proliferation GO:0042127 359 0.027
Rat
regulation of secretion by cell GO:1903530 208 0.027
nucleotide catabolic process GO:0009166 139 0.027
secretion GO:0046903 307 0.026
Rat
multicellular organism reproduction GO:0032504 233 0.026
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
behavior GO:0007610 205 0.026
regulation of neurogenesis GO:0050767 247 0.026
Rat
amine metabolic process GO:0009308 38 0.026
regulation of programmed cell death GO:0043067 341 0.026
reproduction GO:0000003 245 0.026
Rat
regulation of protein kinase activity GO:0045859 105 0.026
cellular component movement GO:0006928 248 0.026
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.025
cellular ketone metabolic process GO:0042180 51 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of purine nucleotide metabolic process GO:1900542 115 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
positive regulation of molecular function GO:0044093 230 0.025
negative regulation of gene expression GO:0010629 199 0.024
regulation of secretion GO:0051046 224 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
cognition GO:0050890 92 0.023
proteolysis GO:0006508 175 0.023
transcription dna templated GO:0006351 377 0.023
regulation of nucleotide metabolic process GO:0006140 117 0.023
purine containing compound catabolic process GO:0072523 138 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
nucleic acid templated transcription GO:0097659 379 0.023
response to vitamin GO:0033273 131 0.023
macromolecule localization GO:0033036 252 0.023
protein phosphorylation GO:0006468 345 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
response to carbohydrate GO:0009743 183 0.023
Rat
protein localization GO:0008104 191 0.023
regulation of membrane potential GO:0042391 110 0.022
positive regulation of cell communication GO:0010647 271 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
organelle organization GO:0006996 266 0.022
Rat
response to oxidative stress GO:0006979 186 0.022
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.022
ion homeostasis GO:0050801 212 0.022
regulation of catabolic process GO:0009894 113 0.022
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.021
positive regulation of cell death GO:0010942 184 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
response to estrogen GO:0043627 232 0.021
Rat
organophosphate biosynthetic process GO:0090407 143 0.021
cellular lipid metabolic process GO:0044255 208 0.021
cell migration GO:0016477 197 0.021
Rat
homeostatic process GO:0042592 331 0.021
Rat
positive regulation of transport GO:0051050 245 0.021
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
secretion by cell GO:0032940 248 0.020
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.020
localization of cell GO:0051674 202 0.020
Rat
rna metabolic process GO:0016070 406 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
regulation of neuron projection development GO:0010975 161 0.020
Rat
intracellular protein transport GO:0006886 79 0.020
positive regulation of cellular component biogenesis GO:0044089 55 0.019
regulation of apoptotic process GO:0042981 335 0.019
aging GO:0007568 241 0.019
regulation of gtpase activity GO:0043087 57 0.019
rhythmic process GO:0048511 156 0.019
ion transmembrane transport GO:0034220 365 0.019
Rat
organonitrogen compound catabolic process GO:1901565 179 0.019
response to decreased oxygen levels GO:0036293 237 0.019
Rat
response to growth factor GO:0070848 189 0.019
Rat
response to hypoxia GO:0001666 231 0.019
Rat
regulation of locomotion GO:0040012 148 0.019
Rat
female pregnancy GO:0007565 122 0.019
Rat
positive regulation of protein metabolic process GO:0051247 178 0.019
cellular macromolecule localization GO:0070727 122 0.019
cellular response to peptide GO:1901653 133 0.019
Rat
nucleotide biosynthetic process GO:0009165 98 0.019
cell motility GO:0048870 202 0.019
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
heterocycle catabolic process GO:0046700 167 0.018
aromatic compound catabolic process GO:0019439 168 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
lipid metabolic process GO:0006629 283 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
cellular component morphogenesis GO:0032989 155 0.018
response to acid chemical GO:0001101 222 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
Rat
regulation of rna biosynthetic process GO:2001141 381 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
synaptic transmission GO:0007268 235 0.018
response to estradiol GO:0032355 164 0.018
rna biosynthetic process GO:0032774 380 0.018
response to bacterium GO:0009617 200 0.018
Rat
cellular response to organonitrogen compound GO:0071417 197 0.018
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
locomotion GO:0040011 237 0.017
Rat
chemical homeostasis GO:0048878 292 0.017
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.017
cell part morphogenesis GO:0032990 123 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
immune system process GO:0002376 204 0.017
Rat
monovalent inorganic cation transport GO:0015672 172 0.017
response to nutrient GO:0007584 248 0.017
divalent inorganic cation transport GO:0072511 134 0.017
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
regulation of system process GO:0044057 208 0.017
purine nucleotide biosynthetic process GO:0006164 83 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
Rat
cellular metal ion homeostasis GO:0006875 172 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of cell motility GO:2000145 131 0.016
Rat
positive regulation of apoptotic process GO:0043065 154 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
male gamete generation GO:0048232 99 0.016
response to alkaloid GO:0043279 132 0.016
Rat
positive regulation of transcription dna templated GO:0045893 197 0.016
inflammatory response to antigenic stimulus GO:0002437 18 0.016
negative regulation of molecular function GO:0044092 133 0.016
response to hydrogen peroxide GO:0042542 89 0.016
Rat
cellular response to abiotic stimulus GO:0071214 85 0.015
Rat
mapk cascade GO:0000165 140 0.015
regulation of ion transport GO:0043269 245 0.015
Rat
negative regulation of cell death GO:0060548 229 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
Rat
response to ketone GO:1901654 182 0.015
Rat
oxidation reduction process GO:0055114 304 0.015
positive regulation of protein modification process GO:0031401 142 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
neuron projection morphogenesis GO:0048812 122 0.015
regulation of protein transport GO:0051223 68 0.015
ribose phosphate biosynthetic process GO:0046390 87 0.015
response to corticosteroid GO:0031960 235 0.015
Rat
response to glucose GO:0009749 136 0.015
Rat
guanosine containing compound metabolic process GO:1901068 74 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
Rat
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
Rat
inorganic ion transmembrane transport GO:0098660 229 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
Rat
cellular cation homeostasis GO:0030003 180 0.015
transmission of nerve impulse GO:0019226 42 0.015
response to molecule of bacterial origin GO:0002237 194 0.014
Rat
sexual reproduction GO:0019953 148 0.014
response to toxic substance GO:0009636 133 0.014
response to hexose GO:0009746 144 0.014
Rat
protein transport GO:0015031 132 0.014
organ regeneration GO:0031100 101 0.014
ras protein signal transduction GO:0007265 29 0.014
carboxylic acid catabolic process GO:0046395 49 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
positive regulation of signaling GO:0023056 270 0.014
dna metabolic process GO:0006259 96 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
positive regulation of secretion GO:0051047 140 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
regeneration GO:0031099 163 0.014
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.014
regulation of hormone levels GO:0010817 187 0.014
cellular homeostasis GO:0019725 252 0.014
Rat
exocytosis GO:0006887 60 0.014
calcium ion transport GO:0006816 131 0.014
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.014
developmental process involved in reproduction GO:0003006 159 0.014
Rat
response to cytokine GO:0034097 215 0.014
Rat
eye morphogenesis GO:0048592 4 0.014
wound healing GO:0042060 122 0.014
Rat
negative regulation of cellular component organization GO:0051129 83 0.014
gamete generation GO:0007276 124 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
small molecule catabolic process GO:0044282 59 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of signal transduction GO:0009967 175 0.013
carboxylic acid transport GO:0046942 115 0.013
gtp catabolic process GO:0006184 71 0.013
nucleosome organization GO:0034728 1 0.013
neuron neuron synaptic transmission GO:0007270 60 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
protein tetramerization GO:0051262 38 0.013
regulation of protein localization GO:0032880 81 0.013
chromatin assembly or disassembly GO:0006333 1 0.013
response to glucocorticoid GO:0051384 223 0.013
Rat
cellular protein localization GO:0034613 122 0.013
bmp signaling pathway GO:0030509 4 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to external biotic stimulus GO:0043207 221 0.013
Rat
regulation of anatomical structure size GO:0090066 135 0.013
gtp metabolic process GO:0046039 72 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
regulation of exocytosis GO:0017157 37 0.012
response to ammonium ion GO:0060359 71 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of kinase activity GO:0043549 117 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
response to biotic stimulus GO:0009607 226 0.012
Rat
positive regulation of rna metabolic process GO:0051254 203 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
Rat
negative regulation of developmental process GO:0051093 125 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
regulation of body fluid levels GO:0050878 90 0.012
Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
spermatogenesis GO:0007283 99 0.012
nucleoside catabolic process GO:0009164 126 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of organelle organization GO:0033043 80 0.012
metal ion transport GO:0030001 289 0.012
Rat
posttranscriptional regulation of gene expression GO:0010608 37 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of amine transport GO:0051952 54 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
regulation of cellular component biogenesis GO:0044087 86 0.011
embryonic skeletal system development GO:0048706 3 0.011
cell morphogenesis GO:0000902 142 0.011
potassium ion transport GO:0006813 97 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
cytoplasmic transport GO:0016482 115 0.011
cation homeostasis GO:0055080 195 0.011
anion transmembrane transport GO:0098656 77 0.011
dna packaging GO:0006323 4 0.011
response to reactive oxygen species GO:0000302 120 0.011
Rat
protein targeting GO:0006605 61 0.011
intracellular transport GO:0046907 185 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to other organism GO:0051707 220 0.011
Rat
reactive nitrogen species metabolic process GO:2001057 1 0.011
positive regulation of ion transport GO:0043270 94 0.011
Rat
establishment of protein localization GO:0045184 141 0.011
single organism behavior GO:0044708 130 0.011
gliogenesis GO:0042063 93 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
response to insulin GO:0032868 133 0.010
Rat
cellular calcium ion homeostasis GO:0006874 160 0.010
protein processing GO:0016485 68 0.010
Rat
cell growth GO:0016049 104 0.010
negative regulation of transport GO:0051051 136 0.010
cell type specific apoptotic process GO:0097285 134 0.010
regulation of protein modification process GO:0031399 194 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
protein localization to organelle GO:0033365 57 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
axis specification GO:0009798 4 0.010
negative regulation of neurogenesis GO:0050768 78 0.010

Serpini1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
Human
nervous system disease DOID:863 0 0.029
Human