Rattus norvegicus

0 known processes

Wfdc15b

WAP four-disulfide core domain 15B

(Aliases: Serpina1c,Pi3,Wfdc14,Skalp)

Wfdc15b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.046
response to extracellular stimulus GO:0009991 380 0.044
single organism reproductive process GO:0044702 297 0.043
response to inorganic substance GO:0010035 377 0.042
reproductive process GO:0022414 372 0.039
positive regulation of cell proliferation GO:0008284 249 0.036
negative regulation of metabolic process GO:0009892 331 0.036
neuron differentiation GO:0030182 368 0.035
regulation of cell proliferation GO:0042127 359 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
organic acid metabolic process GO:0006082 292 0.033
cation homeostasis GO:0055080 195 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
lipid metabolic process GO:0006629 283 0.032
homeostatic process GO:0042592 331 0.032
intracellular signal transduction GO:0035556 314 0.030
regulation of cellular component organization GO:0051128 368 0.030
cation transport GO:0006812 382 0.030
ion homeostasis GO:0050801 212 0.030
chemical homeostasis GO:0048878 292 0.030
regulation of multicellular organismal development GO:2000026 376 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
multi organism reproductive process GO:0044703 262 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
central nervous system development GO:0007417 311 0.029
cell cell signaling GO:0007267 335 0.028
metal ion transport GO:0030001 289 0.028
multicellular organism reproduction GO:0032504 233 0.028
single organism biosynthetic process GO:0044711 342 0.028
brain development GO:0007420 247 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
response to nutrient GO:0007584 248 0.027
regulation of molecular function GO:0065009 398 0.027
oxoacid metabolic process GO:0043436 290 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
negative regulation of cell death GO:0060548 229 0.026
protein phosphorylation GO:0006468 345 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
neuron projection development GO:0031175 273 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
cellular amine metabolic process GO:0044106 38 0.026
cellular response to hormone stimulus GO:0032870 247 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of catalytic activity GO:0050790 304 0.025
regulation of cell differentiation GO:0045595 320 0.025
catabolic process GO:0009056 351 0.025
response to peptide GO:1901652 292 0.025
positive regulation of transport GO:0051050 245 0.025
cellular response to stress GO:0033554 269 0.025
cellular ketone metabolic process GO:0042180 51 0.024
rna biosynthetic process GO:0032774 380 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
head development GO:0060322 247 0.024
regulation of apoptotic process GO:0042981 335 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
cellular component biogenesis GO:0044085 368 0.024
rna metabolic process GO:0016070 406 0.023
response to oxygen levels GO:0070482 265 0.023
reproduction GO:0000003 245 0.023
apoptotic process GO:0006915 381 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
positive regulation of cell communication GO:0010647 271 0.023
metal ion homeostasis GO:0055065 186 0.023
amine metabolic process GO:0009308 38 0.023
response to peptide hormone GO:0043434 278 0.023
cellular metal ion homeostasis GO:0006875 172 0.023
response to estrogen GO:0043627 232 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
cell projection organization GO:0030030 302 0.022
programmed cell death GO:0012501 392 0.022
regulation of cell development GO:0060284 263 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
cellular cation homeostasis GO:0030003 180 0.022
neuron development GO:0048666 286 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
developmental process involved in reproduction GO:0003006 159 0.022
positive regulation of signaling GO:0023056 270 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
cellular catabolic process GO:0044248 295 0.021
response to corticosteroid GO:0031960 235 0.021
regulation of rna metabolic process GO:0051252 391 0.021
calcium ion homeostasis GO:0055074 162 0.021
cellular ion homeostasis GO:0006873 184 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
regulation of phosphorylation GO:0042325 248 0.021
cellular component movement GO:0006928 248 0.021
regulation of signal transduction GO:0009966 318 0.021
regulation of protein metabolic process GO:0051246 289 0.021
response to glucocorticoid GO:0051384 223 0.021
growth GO:0040007 165 0.020
positive regulation of developmental process GO:0051094 283 0.020
cellular chemical homeostasis GO:0055082 247 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
transmembrane transport GO:0055085 412 0.020
response to metal ion GO:0010038 253 0.020
secretion GO:0046903 307 0.020
cellular response to lipid GO:0071396 201 0.020
defense response GO:0006952 194 0.019
macromolecule localization GO:0033036 252 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
circulatory system process GO:0003013 183 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of ion transport GO:0043269 245 0.019
protein complex assembly GO:0006461 263 0.019
regulation of hormone levels GO:0010817 187 0.019
regulation of system process GO:0044057 208 0.019
sexual reproduction GO:0019953 148 0.019
blood circulation GO:0008015 183 0.019
organic substance catabolic process GO:1901575 316 0.019
signal release GO:0023061 145 0.019
transcription dna templated GO:0006351 377 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
nucleic acid templated transcription GO:0097659 379 0.018
purine containing compound metabolic process GO:0072521 253 0.018
ion transmembrane transport GO:0034220 365 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of cellular localization GO:0060341 263 0.018
organophosphate metabolic process GO:0019637 370 0.018
response to acid chemical GO:0001101 222 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of transcription dna templated GO:0006355 374 0.018
response to hypoxia GO:0001666 231 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
reproductive structure development GO:0048608 128 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
immune system process GO:0002376 204 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
macromolecular complex assembly GO:0065003 273 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
nucleotide metabolic process GO:0009117 279 0.018
regulation of programmed cell death GO:0043067 341 0.018
cellular component assembly GO:0022607 360 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to ketone GO:1901654 182 0.017
aging GO:0007568 241 0.017
synaptic transmission GO:0007268 235 0.017
regulation of secretion GO:0051046 224 0.017
secretion by cell GO:0032940 248 0.017
locomotion GO:0040011 237 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
anion transport GO:0006820 178 0.017
positive regulation of molecular function GO:0044093 230 0.017
single organism organelle organization GO:1902589 180 0.017
multi multicellular organism process GO:0044706 138 0.017
regulation of nervous system development GO:0051960 264 0.017
regulation of response to stress GO:0080134 126 0.017
protein complex biogenesis GO:0070271 263 0.017
regulation of protein modification process GO:0031399 194 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
positive regulation of cell differentiation GO:0045597 217 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
regulation of secretion by cell GO:1903530 208 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
organelle organization GO:0006996 266 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
muscle system process GO:0003012 115 0.016
reproductive system development GO:0061458 128 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
protein complex subunit organization GO:0071822 302 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
regulation of neuron differentiation GO:0045664 208 0.016
single organism catabolic process GO:0044712 283 0.015
divalent metal ion transport GO:0070838 132 0.015
inflammatory response GO:0006954 150 0.015
response to ethanol GO:0045471 162 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
response to decreased oxygen levels GO:0036293 237 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
gamete generation GO:0007276 124 0.015
regulation of cell projection organization GO:0031344 175 0.015
response to biotic stimulus GO:0009607 226 0.015
proteolysis GO:0006508 175 0.015
regulation of homeostatic process GO:0032844 101 0.015
regeneration GO:0031099 163 0.015
nitrogen compound transport GO:0071705 229 0.015
response to wounding GO:0009611 254 0.015
regulation of membrane potential GO:0042391 110 0.015
small molecule biosynthetic process GO:0044283 124 0.015
neurological system process GO:0050877 219 0.015
axis specification GO:0009798 4 0.015
calcium ion transport GO:0006816 131 0.014
response to cytokine GO:0034097 215 0.014
cell motility GO:0048870 202 0.014
oxidation reduction process GO:0055114 304 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
intracellular transport GO:0046907 185 0.014
localization of cell GO:0051674 202 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
tissue development GO:0009888 252 0.014
positive regulation of gene expression GO:0010628 244 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
divalent inorganic cation transport GO:0072511 134 0.014
response to estradiol GO:0032355 164 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of signal transduction GO:0009967 175 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
gland development GO:0048732 155 0.014
sex differentiation GO:0007548 113 0.014
female pregnancy GO:0007565 122 0.014
regulation of growth GO:0040008 105 0.013
negative regulation of molecular function GO:0044092 133 0.013
mapk cascade GO:0000165 140 0.013
response to oxidative stress GO:0006979 186 0.013
response to vitamin GO:0033273 131 0.013
cell growth GO:0016049 104 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
cell migration GO:0016477 197 0.013
negative regulation of gene expression GO:0010629 199 0.013
organ regeneration GO:0031100 101 0.013
establishment of tissue polarity GO:0007164 2 0.013
spermatogenesis GO:0007283 99 0.013
hormone secretion GO:0046879 115 0.013
salivary gland development GO:0007431 3 0.013
regulation of neuron projection development GO:0010975 161 0.013
regulation of metal ion transport GO:0010959 118 0.013
response to insulin GO:0032868 133 0.013
gastrulation GO:0007369 2 0.013
response to radiation GO:0009314 137 0.013
organic anion transport GO:0015711 132 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
cation transmembrane transport GO:0098655 263 0.013
nucleoside metabolic process GO:0009116 179 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
response to molecule of bacterial origin GO:0002237 194 0.012
cellular response to external stimulus GO:0071496 118 0.012
development of primary sexual characteristics GO:0045137 107 0.012
peptidyl amino acid modification GO:0018193 126 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
vesicle mediated transport GO:0016192 181 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of ion homeostasis GO:2000021 63 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
regulation of hormone secretion GO:0046883 106 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
heart morphogenesis GO:0003007 3 0.012
response to growth factor GO:0070848 189 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
positive regulation of cell development GO:0010720 176 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
response to alkaloid GO:0043279 132 0.012
regulation of synaptic transmission GO:0050804 141 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
negative regulation of innate immune response GO:0045824 4 0.012
protein localization GO:0008104 191 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
sequestering of metal ion GO:0051238 9 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.012
embryonic pattern specification GO:0009880 1 0.012
chromosome segregation GO:0007059 2 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of secretion GO:0051047 140 0.012
male gamete generation GO:0048232 99 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
ras protein signal transduction GO:0007265 29 0.012
response to toxic substance GO:0009636 133 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
gonad development GO:0008406 104 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
response to other organism GO:0051707 220 0.011
circadian rhythm GO:0007623 88 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
cellular lipid metabolic process GO:0044255 208 0.011
protein oligomerization GO:0051259 191 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
cellular response to peptide GO:1901653 133 0.011
fatty acid metabolic process GO:0006631 99 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
anterior posterior pattern specification GO:0009952 1 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to monosaccharide GO:0034284 159 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
hormone transport GO:0009914 121 0.011
cell adhesion GO:0007155 110 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
behavior GO:0007610 205 0.011
regulation of cell motility GO:2000145 131 0.011
response to external biotic stimulus GO:0043207 221 0.011
single organism intracellular transport GO:1902582 166 0.011
organic acid transport GO:0015849 116 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to hexose GO:0009746 144 0.011
regulation of cellular component movement GO:0051270 150 0.011
carboxylic acid transport GO:0046942 115 0.011
response to carbohydrate GO:0009743 183 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
maintenance of location GO:0051235 17 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
response to mechanical stimulus GO:0009612 134 0.011
negative regulation of transport GO:0051051 136 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of blood circulation GO:1903522 110 0.011
meiotic cell cycle process GO:1903046 3 0.011
lipid biosynthetic process GO:0008610 128 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
lipid storage GO:0019915 1 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
transmission of nerve impulse GO:0019226 42 0.010
regulation of calcium ion transport GO:0051924 77 0.010
muscle cell proliferation GO:0033002 84 0.010
response to lipopolysaccharide GO:0032496 191 0.010
muscle contraction GO:0006936 88 0.010
wound healing GO:0042060 122 0.010
positive regulation of blood circulation GO:1903524 65 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
positive regulation of locomotion GO:0040017 102 0.010
action potential GO:0001508 54 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
response to reactive oxygen species GO:0000302 120 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
regulation of hydrolase activity GO:0051336 143 0.010
regulation of body fluid levels GO:0050878 90 0.010
regulation of muscle system process GO:0090257 79 0.010
sodium ion transmembrane transport GO:0035725 67 0.010
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
aromatic compound catabolic process GO:0019439 168 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
forebrain development GO:0030900 98 0.010
immune response GO:0006955 104 0.010
positive regulation of cell migration GO:0030335 96 0.010
response to bacterium GO:0009617 200 0.010
regulation of blood pressure GO:0008217 83 0.010
hepaticobiliary system development GO:0061008 90 0.010
cell activation GO:0001775 97 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
positive regulation of cell death GO:0010942 184 0.010

Wfdc15b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.015
musculoskeletal system disease DOID:17 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
central nervous system disease DOID:331 0 0.010