Rattus norvegicus

0 known processes

Shoc2

soc-2 (suppressor of clear) homolog (C. elegans)

Shoc2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.113
transcription dna templated GO:0006351 377 0.098
nucleic acid templated transcription GO:0097659 379 0.095
regulation of rna metabolic process GO:0051252 391 0.086
transcription from rna polymerase ii promoter GO:0006366 252 0.085
regulation of transcription dna templated GO:0006355 374 0.083
rna metabolic process GO:0016070 406 0.079
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.077
positive regulation of biosynthetic process GO:0009891 319 0.076
rna biosynthetic process GO:0032774 380 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.067
regulation of programmed cell death GO:0043067 341 0.067
regulation of nucleic acid templated transcription GO:1903506 380 0.064
apoptotic process GO:0006915 381 0.063
anatomical structure morphogenesis GO:0009653 298 0.061
regulation of catalytic activity GO:0050790 304 0.056
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
negative regulation of metabolic process GO:0009892 331 0.052
programmed cell death GO:0012501 392 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.048
positive regulation of transcription dna templated GO:0045893 197 0.048
regulation of phosphorus metabolic process GO:0051174 349 0.045
Fly
regulation of apoptotic process GO:0042981 335 0.045
regulation of molecular function GO:0065009 398 0.045
single organism reproductive process GO:0044702 297 0.045
positive regulation of gene expression GO:0010628 244 0.044
single organism organelle organization GO:1902589 180 0.043
anterior posterior pattern specification GO:0009952 1 0.043
cellular component morphogenesis GO:0032989 155 0.042
organelle organization GO:0006996 266 0.042
positive regulation of nucleic acid templated transcription GO:1903508 197 0.042
cell projection organization GO:0030030 302 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
Fly
cellular component movement GO:0006928 248 0.040
response to inorganic substance GO:0010035 377 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
Fly
reproduction GO:0000003 245 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
regulation of protein metabolic process GO:0051246 289 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
positive regulation of rna metabolic process GO:0051254 203 0.035
reproductive process GO:0022414 372 0.035
protein phosphorylation GO:0006468 345 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
locomotion GO:0040011 237 0.034
muscle system process GO:0003012 115 0.033
negative regulation of gene expression GO:0010629 199 0.033
regulation of protein modification process GO:0031399 194 0.033
positive regulation of signal transduction GO:0009967 175 0.033
Human Fly
regulation of cellular protein metabolic process GO:0032268 267 0.032
multicellular organism reproduction GO:0032504 233 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.031
regulation of protein phosphorylation GO:0001932 183 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
negative regulation of protein metabolic process GO:0051248 114 0.030
tissue development GO:0009888 252 0.030
organic acid metabolic process GO:0006082 292 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
organophosphate metabolic process GO:0019637 370 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
anatomical structure formation involved in morphogenesis GO:0048646 83 0.029
cellular component biogenesis GO:0044085 368 0.029
negative regulation of programmed cell death GO:0043069 183 0.028
cell morphogenesis GO:0000902 142 0.028
blood circulation GO:0008015 183 0.028
synaptic transmission GO:0007268 235 0.028
regulation of signal transduction GO:0009966 318 0.028
Human Fly
regulation of cell proliferation GO:0042127 359 0.027
head development GO:0060322 247 0.027
regulation of cellular component organization GO:0051128 368 0.027
homeostatic process GO:0042592 331 0.027
response to extracellular stimulus GO:0009991 380 0.027
cellular component assembly GO:0022607 360 0.027
amine metabolic process GO:0009308 38 0.026
intracellular transport GO:0046907 185 0.026
cellular response to stress GO:0033554 269 0.026
cellular amine metabolic process GO:0044106 38 0.026
cation transport GO:0006812 382 0.026
regulation of intracellular signal transduction GO:1902531 218 0.025
Human Fly
response to estrogen GO:0043627 232 0.025
neuron development GO:0048666 286 0.025
neuron differentiation GO:0030182 368 0.025
single organism intracellular transport GO:1902582 166 0.025
single organism catabolic process GO:0044712 283 0.025
cell type specific apoptotic process GO:0097285 134 0.025
response to nutrient levels GO:0031667 370 0.024
multi organism reproductive process GO:0044703 262 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
chemical homeostasis GO:0048878 292 0.024
brain development GO:0007420 247 0.024
positive regulation of molecular function GO:0044093 230 0.024
regulation of system process GO:0044057 208 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
metal ion transport GO:0030001 289 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
intracellular signal transduction GO:0035556 314 0.023
Human Fly
cellular ketone metabolic process GO:0042180 51 0.023
localization of cell GO:0051674 202 0.023
sexual reproduction GO:0019953 148 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of signaling GO:0023056 270 0.023
Human Fly
central nervous system development GO:0007417 311 0.023
response to metal ion GO:0010038 253 0.023
regulation of cell differentiation GO:0045595 320 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
circulatory system process GO:0003013 183 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.021
Human Fly
circulatory system development GO:0072359 134 0.021
neuron projection development GO:0031175 273 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
Fly
cellular response to oxygen containing compound GO:1901701 386 0.021
neurological system process GO:0050877 219 0.021
rhythmic process GO:0048511 156 0.021
cellular chemical homeostasis GO:0055082 247 0.021
metal ion homeostasis GO:0055065 186 0.021
regulation of cellular component movement GO:0051270 150 0.021
response to estradiol GO:0032355 164 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
Human Fly
regulation of phosphorylation GO:0042325 248 0.021
Fly
single organism biosynthetic process GO:0044711 342 0.021
catabolic process GO:0009056 351 0.021
positive regulation of protein metabolic process GO:0051247 178 0.020
cell cell signaling GO:0007267 335 0.020
positive regulation of cell communication GO:0010647 271 0.020
Human Fly
cell projection morphogenesis GO:0048858 123 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
Fly
oxoacid metabolic process GO:0043436 290 0.020
positive regulation of protein modification process GO:0031401 142 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
heart morphogenesis GO:0003007 3 0.020
axis specification GO:0009798 4 0.019
negative regulation of cell death GO:0060548 229 0.019
cellular homeostasis GO:0019725 252 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
membrane organization GO:0061024 94 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to cytokine GO:0034097 215 0.018
response to carbohydrate GO:0009743 183 0.018
cellular response to external stimulus GO:0071496 118 0.018
behavior GO:0007610 205 0.018
cell migration GO:0016477 197 0.018
cellular catabolic process GO:0044248 295 0.018
response to radiation GO:0009314 137 0.018
negative regulation of signaling GO:0023057 157 0.018
aging GO:0007568 241 0.018
negative regulation of cell communication GO:0010648 158 0.018
response to nutrient GO:0007584 248 0.018
ribose phosphate metabolic process GO:0019693 235 0.017
response to decreased oxygen levels GO:0036293 237 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
Fly
regulation of membrane potential GO:0042391 110 0.017
cellular ion homeostasis GO:0006873 184 0.017
protein complex assembly GO:0006461 263 0.017
neuron projection morphogenesis GO:0048812 122 0.017
wound healing GO:0042060 122 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
positive regulation of developmental process GO:0051094 283 0.017
macromolecular complex assembly GO:0065003 273 0.017
transmembrane transport GO:0055085 412 0.016
response to hexose GO:0009746 144 0.016
proteolysis GO:0006508 175 0.016
response to wounding GO:0009611 254 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
nucleotide catabolic process GO:0009166 139 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
regulation of locomotion GO:0040012 148 0.016
axon development GO:0061564 96 0.016
heterocycle catabolic process GO:0046700 167 0.016
cell motility GO:0048870 202 0.016
nucleotide metabolic process GO:0009117 279 0.016
positive regulation of cell death GO:0010942 184 0.016
neuron death GO:0070997 127 0.016
cell part morphogenesis GO:0032990 123 0.016
embryonic pattern specification GO:0009880 1 0.016
cardiovascular system development GO:0072358 134 0.016
ribonucleotide metabolic process GO:0009259 231 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
regulation of growth GO:0040008 105 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
negative regulation of molecular function GO:0044092 133 0.015
gland development GO:0048732 155 0.015
response to vitamin GO:0033273 131 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cation homeostasis GO:0055080 195 0.015
response to mechanical stimulus GO:0009612 134 0.015
protein complex biogenesis GO:0070271 263 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
regulation of cell development GO:0060284 263 0.015
regulation of neuron differentiation GO:0045664 208 0.015
secretion GO:0046903 307 0.015
vasculature development GO:0001944 70 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
regulation of cell projection organization GO:0031344 175 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
organophosphate catabolic process GO:0046434 148 0.014
nucleoside metabolic process GO:0009116 179 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of cell motility GO:2000145 131 0.014
ion homeostasis GO:0050801 212 0.014
regulation of nervous system development GO:0051960 264 0.014
response to acid chemical GO:0001101 222 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
chromosome segregation GO:0007059 2 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of catabolic process GO:0009894 113 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
ion transmembrane transport GO:0034220 365 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
purine containing compound metabolic process GO:0072521 253 0.014
cell cycle GO:0007049 101 0.014
response to oxidative stress GO:0006979 186 0.014
regulation of mapk cascade GO:0043408 116 0.013
Fly
organic substance catabolic process GO:1901575 316 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of neurogenesis GO:0050767 247 0.013
regulation of kinase activity GO:0043549 117 0.013
growth GO:0040007 165 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
response to oxygen levels GO:0070482 265 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular cation homeostasis GO:0030003 180 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
mapk cascade GO:0000165 140 0.013
Fly
macromolecule localization GO:0033036 252 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
eye morphogenesis GO:0048592 4 0.013
anion transport GO:0006820 178 0.013
response to peptide GO:1901652 292 0.013
cell cycle checkpoint GO:0000075 2 0.013
regulation of neuron death GO:1901214 115 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
response to corticosteroid GO:0031960 235 0.013
organ morphogenesis GO:0009887 75 0.012
protein complex subunit organization GO:0071822 302 0.012
response to glucose GO:0009749 136 0.012
response to peptide hormone GO:0043434 278 0.012
response to hypoxia GO:0001666 231 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
dna metabolic process GO:0006259 96 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
gamete generation GO:0007276 124 0.012
blood vessel development GO:0001568 69 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
negative regulation of transport GO:0051051 136 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
Human Fly
regulation of neuron projection development GO:0010975 161 0.012
muscle contraction GO:0006936 88 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
regulation of transferase activity GO:0051338 123 0.012
axonogenesis GO:0007409 71 0.012
regulation of secretion by cell GO:1903530 208 0.012
regulation of muscle system process GO:0090257 79 0.012
regulation of hormone levels GO:0010817 187 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of cell migration GO:0030334 128 0.011
cell growth GO:0016049 104 0.011
regeneration GO:0031099 163 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of cellular localization GO:0060341 263 0.011
chemotaxis GO:0006935 66 0.011
nitrogen compound transport GO:0071705 229 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
immune system process GO:0002376 204 0.011
protein transport GO:0015031 132 0.011
protein localization GO:0008104 191 0.011
lipid storage GO:0019915 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
single organism behavior GO:0044708 130 0.011
response to ketone GO:1901654 182 0.011
regulation of protein kinase activity GO:0045859 105 0.011
response to growth factor GO:0070848 189 0.011
regulation of embryonic development GO:0045995 2 0.011
muscle cell proliferation GO:0033002 84 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
actin mediated cell contraction GO:0070252 12 0.011
muscle structure development GO:0061061 87 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
multicellular organismal signaling GO:0035637 44 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
response to monosaccharide GO:0034284 159 0.011
response to organophosphorus GO:0046683 102 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
regulation of hydrolase activity GO:0051336 143 0.011
vesicle mediated transport GO:0016192 181 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
spermatogenesis GO:0007283 99 0.011
cellular protein localization GO:0034613 122 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
purine containing compound catabolic process GO:0072523 138 0.010
circadian rhythm GO:0007623 88 0.010
cellular response to lipid GO:0071396 201 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
developmental process involved in reproduction GO:0003006 159 0.010
positive regulation of cell motility GO:2000147 97 0.010
divalent metal ion transport GO:0070838 132 0.010
cytoplasmic transport GO:0016482 115 0.010
sulfur compound metabolic process GO:0006790 70 0.010

Shoc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.013