Rattus norvegicus

0 known processes

Dscr6

Down syndrome critical region homolog 6 (human)

Dscr6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to oxygen containing compound GO:1901701 386 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
nucleic acid templated transcription GO:0097659 379 0.047
rna biosynthetic process GO:0032774 380 0.047
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.046
transcription dna templated GO:0006351 377 0.046
rna metabolic process GO:0016070 406 0.042
positive regulation of biosynthetic process GO:0009891 319 0.040
macromolecular complex assembly GO:0065003 273 0.039
protein complex subunit organization GO:0071822 302 0.039
positive regulation of molecular function GO:0044093 230 0.038
regulation of rna metabolic process GO:0051252 391 0.037
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.036
protein complex biogenesis GO:0070271 263 0.036
macromolecular complex subunit organization GO:0043933 339 0.036
metal ion transport GO:0030001 289 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.034
transmembrane transport GO:0055085 412 0.034
negative regulation of biosynthetic process GO:0009890 168 0.033
central nervous system development GO:0007417 311 0.032
cellular response to stress GO:0033554 269 0.032
cellular component assembly GO:0022607 360 0.031
regulation of cell differentiation GO:0045595 320 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
regulation of cell proliferation GO:0042127 359 0.031
cellular component biogenesis GO:0044085 368 0.030
protein complex assembly GO:0006461 263 0.030
response to nutrient levels GO:0031667 370 0.030
regulation of transcription dna templated GO:0006355 374 0.029
cellular chemical homeostasis GO:0055082 247 0.029
response to extracellular stimulus GO:0009991 380 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
brain development GO:0007420 247 0.029
cellular catabolic process GO:0044248 295 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
negative regulation of metabolic process GO:0009892 331 0.028
cation transport GO:0006812 382 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
catabolic process GO:0009056 351 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
anterior posterior pattern specification GO:0009952 1 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
alpha amino acid metabolic process GO:1901605 71 0.026
protein oligomerization GO:0051259 191 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.026
organic substance catabolic process GO:1901575 316 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
cellular amino acid metabolic process GO:0006520 107 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
response to inorganic substance GO:0010035 377 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
response to oxygen levels GO:0070482 265 0.024
oxoacid metabolic process GO:0043436 290 0.023
ion homeostasis GO:0050801 212 0.023
response to peptide hormone GO:0043434 278 0.023
response to hypoxia GO:0001666 231 0.023
single organism catabolic process GO:0044712 283 0.023
tissue development GO:0009888 252 0.023
cellular amine metabolic process GO:0044106 38 0.022
amine metabolic process GO:0009308 38 0.022
heterocycle catabolic process GO:0046700 167 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.022
purine containing compound metabolic process GO:0072521 253 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
regulation of protein metabolic process GO:0051246 289 0.022
response to biotic stimulus GO:0009607 226 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
response to peptide GO:1901652 292 0.021
response to estradiol GO:0032355 164 0.021
neuron development GO:0048666 286 0.021
regulation of cellular component organization GO:0051128 368 0.021
response to monosaccharide GO:0034284 159 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
cellular homeostasis GO:0019725 252 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
regulation of catalytic activity GO:0050790 304 0.021
negative regulation of gene expression GO:0010629 199 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
response to decreased oxygen levels GO:0036293 237 0.021
organic acid metabolic process GO:0006082 292 0.021
response to ketone GO:1901654 182 0.020
neuron projection development GO:0031175 273 0.020
regulation of molecular function GO:0065009 398 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.020
organelle organization GO:0006996 266 0.020
positive regulation of gene expression GO:0010628 244 0.020
response to other organism GO:0051707 220 0.020
response to carbohydrate GO:0009743 183 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
response to external biotic stimulus GO:0043207 221 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
protein phosphorylation GO:0006468 345 0.019
anion transport GO:0006820 178 0.019
programmed cell death GO:0012501 392 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
single organism biosynthetic process GO:0044711 342 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.018
response to hexose GO:0009746 144 0.018
neuron differentiation GO:0030182 368 0.018
epithelium development GO:0060429 96 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
intracellular signal transduction GO:0035556 314 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
cellular ion homeostasis GO:0006873 184 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cell communication involved in cardiac conduction GO:0086065 2 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
organ morphogenesis GO:0009887 75 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
calcium ion homeostasis GO:0055074 162 0.017
chemical homeostasis GO:0048878 292 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
neuron projection morphogenesis GO:0048812 122 0.017
positive regulation of developmental process GO:0051094 283 0.016
regulation of signal transduction GO:0009966 318 0.016
response to metal ion GO:0010038 253 0.016
single organism intracellular transport GO:1902582 166 0.016
nucleotide metabolic process GO:0009117 279 0.016
circulatory system process GO:0003013 183 0.016
nucleotide catabolic process GO:0009166 139 0.016
cellular cation homeostasis GO:0030003 180 0.016
response to glucose GO:0009749 136 0.016
secretion by cell GO:0032940 248 0.016
aromatic compound catabolic process GO:0019439 168 0.016
cell projection organization GO:0030030 302 0.016
chemosensory behavior GO:0007635 2 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.015
regulation of metal ion transport GO:0010959 118 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
positive regulation of protein modification process GO:0031401 142 0.015
regulation of cell development GO:0060284 263 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of membrane potential GO:0042391 110 0.015
positive regulation of signaling GO:0023056 270 0.015
axis specification GO:0009798 4 0.015
reproductive process GO:0022414 372 0.015
developmental process involved in reproduction GO:0003006 159 0.015
proteolysis GO:0006508 175 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of system process GO:0044057 208 0.014
circulatory system development GO:0072359 134 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
localization of cell GO:0051674 202 0.014
protein localization GO:0008104 191 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
response to ethanol GO:0045471 162 0.014
regulation of cell projection organization GO:0031344 175 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
response to oxidative stress GO:0006979 186 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
defense response GO:0006952 194 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
cardiovascular system development GO:0072358 134 0.013
response to nutrient GO:0007584 248 0.013
apoptotic process GO:0006915 381 0.013
cell cell signaling GO:0007267 335 0.013
positive regulation of cell development GO:0010720 176 0.013
eye morphogenesis GO:0048592 4 0.013
cytoskeleton organization GO:0007010 111 0.013
secretion GO:0046903 307 0.013
intracellular transport GO:0046907 185 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
heart morphogenesis GO:0003007 3 0.012
single organism organelle organization GO:1902589 180 0.012
regulation of nervous system development GO:0051960 264 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
negative regulation of cell communication GO:0010648 158 0.012
cellular ketone metabolic process GO:0042180 51 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
response to cytokine GO:0034097 215 0.012
cytoplasmic transport GO:0016482 115 0.012
tube development GO:0035295 89 0.012
negative regulation of cell death GO:0060548 229 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
regulation of protein modification process GO:0031399 194 0.012
organophosphate metabolic process GO:0019637 370 0.012
response to estrogen GO:0043627 232 0.012
blood circulation GO:0008015 183 0.012
epithelial cell differentiation GO:0030855 71 0.012
regulation of immune system process GO:0002682 123 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
single organism reproductive process GO:0044702 297 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.012
response to acid chemical GO:0001101 222 0.012
cardiac conduction GO:0061337 2 0.012
neurological system process GO:0050877 219 0.012
reproductive structure development GO:0048608 128 0.012
positive regulation of nervous system development GO:0051962 178 0.012
urogenital system development GO:0001655 78 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
head development GO:0060322 247 0.012
divalent inorganic cation transport GO:0072511 134 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
ion transmembrane transport GO:0034220 365 0.012
regulation of ion transport GO:0043269 245 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
regulation of neurogenesis GO:0050767 247 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of protein kinase activity GO:0045859 105 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of transport GO:0051050 245 0.011
regulation of apoptotic process GO:0042981 335 0.011
purine containing compound catabolic process GO:0072523 138 0.011
regulation of programmed cell death GO:0043067 341 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
response to fatty acid GO:0070542 65 0.011
aging GO:0007568 241 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
gliogenesis GO:0042063 93 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
behavior GO:0007610 205 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cellular component movement GO:0006928 248 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of kinase activity GO:0043549 117 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of signal transduction GO:0009967 175 0.011
growth GO:0040007 165 0.011
regulation of cell cycle GO:0051726 73 0.011
negative regulation of innate immune response GO:0045824 4 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
second messenger mediated signaling GO:0019932 51 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
mesoderm development GO:0007498 2 0.011
response to vitamin GO:0033273 131 0.011
macromolecule catabolic process GO:0009057 58 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
macromolecule localization GO:0033036 252 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
homeostatic process GO:0042592 331 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
reproduction GO:0000003 245 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
organophosphate catabolic process GO:0046434 148 0.011
cell fate determination GO:0001709 2 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
innate immune response GO:0045087 35 0.010
development of primary sexual characteristics GO:0045137 107 0.010
nitrogen compound transport GO:0071705 229 0.010
lipid metabolic process GO:0006629 283 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
positive regulation of cell death GO:0010942 184 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
single organism cellular localization GO:1902580 102 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
chromosome segregation GO:0007059 2 0.010
response to radiation GO:0009314 137 0.010
olfactory behavior GO:0042048 2 0.010
tube formation GO:0035148 3 0.010
epithelial cell proliferation GO:0050673 54 0.010
sex differentiation GO:0007548 113 0.010
cation homeostasis GO:0055080 195 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
response to wounding GO:0009611 254 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
nucleoside metabolic process GO:0009116 179 0.010
response to toxic substance GO:0009636 133 0.010
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.010

Dscr6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
urinary system disease DOID:18 0 0.010